Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability.

PubWeight™: 7.11‹?› | Rank: Top 1%

🔗 View Article (PMC 2919168)

Published in Am J Psychiatry on June 01, 2003

Authors

R Andrew Chambers1, Jane R Taylor, Marc N Potenza

Author Affiliations

1: Connecticut Mental health Center, the Problem Grambling Clinic, Yale University School of Medicine, New Haven, CT 06508, USA. robert.chambers@yale.edu

Associated clinical trials:

Screening for Youth Alcohol and Drug Use: A Study of Primary Care Providers | NCT02408952

Articles citing this

(truncated to the top 100)

A Social Neuroscience Perspective on Adolescent Risk-Taking. Dev Rev (2008) 9.52

Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci (2008) 6.97

The triadic model perspective for the study of adolescent motivated behavior. Brain Cogn (2014) 4.16

The role of impulsive behavior in drug abuse. Psychopharmacology (Berl) (2008) 3.74

Triadic model of the neurobiology of motivated behavior in adolescence. Psychol Med (2006) 3.62

Compulsive features in behavioural addictions: the case of pathological gambling. Addiction (2011) 3.28

Behavioral and neuroeconomics of drug addiction: competing neural systems and temporal discounting processes. Drug Alcohol Depend (2006) 3.26

What has fMRI told us about the development of cognitive control through adolescence? Brain Cogn (2009) 3.08

Early-onset drug use and risk for drug dependence problems. Addict Behav (2008) 3.01

The dynamic effects of nicotine on the developing brain. Pharmacol Ther (2009) 3.01

A unified framework for addiction: vulnerabilities in the decision process. Behav Brain Sci (2008) 2.83

White matter development in adolescence: a DTI study. Cereb Cortex (2010) 2.44

Neural substrates of choice selection in adults and adolescents: development of the ventrolateral prefrontal and anterior cingulate cortices. Neuropsychologia (2006) 2.44

Review. The neurobiology of pathological gambling and drug addiction: an overview and new findings. Philos Trans R Soc Lond B Biol Sci (2008) 2.40

Immaturities in reward processing and its influence on inhibitory control in adolescence. Cereb Cortex (2009) 2.38

Impulsivity, attention, memory, and decision-making among adolescent marijuana users. Psychopharmacology (Berl) (2012) 2.36

Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study. Brain (2009) 2.35

The neurobiology and genetics of impulse control disorders: relationships to drug addictions. Biochem Pharmacol (2007) 2.22

Are adolescents more vulnerable to drug addiction than adults? Evidence from animal models. Psychopharmacology (Berl) (2009) 2.06

Cognitive dysfunction and anxious-impulsive personality traits are endophenotypes for drug dependence. Am J Psychiatry (2012) 2.05

Neurobiology of the adolescent brain and behavior: implications for substance use disorders. J Am Acad Child Adolesc Psychiatry (2010) 2.02

Probability and predictors of remission from life-time nicotine, alcohol, cannabis or cocaine dependence: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Addiction (2010) 1.99

A developmental neurobiological model of motivated behavior: anatomy, connectivity and ontogeny of the triadic nodes. Neurosci Biobehav Rev (2008) 1.95

Profile of executive deficits in cocaine and heroin polysubstance users: common and differential effects on separate executive components. Psychopharmacology (Berl) (2006) 1.92

Adolescent development of the reward system. Front Hum Neurosci (2010) 1.90

The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia. Behav Brain Res (2008) 1.84

Nonmedical Prescription Opioid Use in Childhood and Early Adolescence Predicts Transitions to Heroin Use in Young Adulthood: A National Study. J Pediatr (2015) 1.67

Transient D1 dopamine receptor expression on prefrontal cortex projection neurons: relationship to enhanced motivational salience of drug cues in adolescence. J Neurosci (2008) 1.66

Adolescent risk taking, impulsivity, and brain development: implications for prevention. Dev Psychobiol (2010) 1.66

Perceived harmfulness predicts nonmedical use of prescription drugs among college students: interactions with sensation-seeking. Prev Sci (2008) 1.65

The nonmedical use of prescription ADHD medications: results from a national Internet panel. Subst Abuse Treat Prev Policy (2007) 1.64

Rewards, aversions and affect in adolescence: emerging convergences across laboratory animal and human data. Dev Cogn Neurosci (2011) 1.61

Long-term effects of laws governing youth access to tobacco. Am J Public Health (2013) 1.60

Prediction of cannabis use disorder between boyhood and young adulthood: clarifying the phenotype and environtype. Am J Addict (2009) 1.58

Neuroscience of behavioral and pharmacological treatments for addictions. Neuron (2011) 1.57

The maturation of incentive processing and cognitive control. Pharmacol Biochem Behav (2009) 1.56

Heritability of delay discounting in adolescence: a longitudinal twin study. Behav Genet (2010) 1.52

Developmental changes in cognitive control through adolescence. Adv Child Dev Behav (2009) 1.48

Adolescents' performance on delay and probability discounting tasks: contributions of age, intelligence, executive functioning, and self-reported externalizing behavior. Pers Individ Dif (2007) 1.46

Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction. Psychopharmacology (Berl) (2006) 1.45

Developmental changes in dopamine neurotransmission in adolescence: behavioral implications and issues in assessment. Brain Cogn (2009) 1.44

Social anxiety disorder and alcohol use disorder co-morbidity in the National Epidemiologic Survey on Alcohol and Related Conditions. Psychol Med (2010) 1.44

Maturing thalamocortical functional connectivity across development. Front Syst Neurosci (2010) 1.43

Executive cognitive functions and impulsivity as correlates of risk taking and problem behavior in preadolescents. Neuropsychologia (2009) 1.43

Alcoholism is a disinhibitory disorder: neurophysiological evidence from a Go/No-Go task. Biol Psychol (2004) 1.42

Neurobehavioral evidence for changes in dopamine system activity during adolescence. Neurosci Biobehav Rev (2009) 1.41

Can adolescents learn self-control? Delay of gratification in the development of control over risk taking. Prev Sci (2010) 1.40

Parental-adolescent drug use discussions: physiological responses and associated outcomes. J Adolesc Health (2014) 1.39

Are executive function and impulsivity antipodes? A conceptual reconstruction with special reference to addiction. Psychopharmacology (Berl) (2012) 1.37

Development of eye-movement control. Brain Cogn (2008) 1.37

Children of addicted women. J Addict Dis (2010) 1.37

Ontogeny of fear-, anxiety- and depression-related behavior across adolescence in C57BL/6J mice. Behav Brain Res (2006) 1.37

Desperately driven and no brakes: developmental stress exposure and subsequent risk for substance abuse. Neurosci Biobehav Rev (2008) 1.37

A targeted review of the neurobiology and genetics of behavioural addictions: an emerging area of research. Can J Psychiatry (2013) 1.37

An investigation of the behavioral actions of ethanol across adolescence in mice. Psychopharmacology (Berl) (2007) 1.36

Substance use and related behaviors among suburban late adolescents: the importance of perceived parent containment. Dev Psychopathol (2008) 1.35

Adult and periadolescent rats differ in expression of nicotinic cholinergic receptor subtypes and in the response of these subtypes to chronic nicotine exposure. Brain Res (2008) 1.32

The emergence of gonadal hormone influences on dopaminergic function during puberty. Horm Behav (2009) 1.31

A role for synaptic plasticity in the adolescent development of executive function. Transl Psychiatry (2013) 1.27

Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons. Neuroscience (2006) 1.24

Long-term risk preference and suboptimal decision making following adolescent alcohol use. Proc Natl Acad Sci U S A (2009) 1.23

Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits. Nicotine Tob Res (2012) 1.22

Low dose nicotine treatment during early adolescence increases subsequent cocaine reward. Neurotoxicol Teratol (2006) 1.22

Pubertal changes in emotional information processing: pupillary, behavioral, and subjective evidence during emotional word identification. Dev Psychopathol (2009) 1.22

Physicians' Counseling of Adolescents Regarding E-Cigarette Use. J Adolesc Health (2015) 1.21

Affective decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in 10th grade Chinese adolescent binge drinkers. Neuropsychologia (2007) 1.20

Risk preference following adolescent alcohol use is associated with corrupted encoding of costs but not rewards by mesolimbic dopamine. Proc Natl Acad Sci U S A (2011) 1.19

Aberrant learning and memory in addiction. Neurobiol Learn Mem (2011) 1.19

Striatal dysfunction marks preexisting risk and medial prefrontal dysfunction is related to problem drinking in children of alcoholics. Biol Psychiatry (2010) 1.19

Monetary reward processing in obese individuals with and without binge eating disorder. Biol Psychiatry (2013) 1.19

Dopamine and impulse control disorders in Parkinson's disease. Ann Neurol (2008) 1.18

Impacts of age of onset of substance use disorders on risk of adult incarceration among disadvantaged urban youth: a propensity score matching approach. Drug Alcohol Depend (2008) 1.18

Hedonic sensitivity in adolescent and adult rats: taste reactivity and voluntary sucrose consumption. Pharmacol Biochem Behav (2009) 1.18

Short- and long-term consequences of nicotine exposure during adolescence for prefrontal cortex neuronal network function. Cold Spring Harb Perspect Med (2012) 1.17

Age-related differences in the blood alcohol levels of Wistar rats. Pharmacol Biochem Behav (2008) 1.17

Predicting response to opiate antagonists and placebo in the treatment of pathological gambling. Psychopharmacology (Berl) (2008) 1.16

Adolescent rats are protected from the conditioned aversive properties of cocaine and lithium chloride. Pharmacol Biochem Behav (2006) 1.16

Parent, peer, and executive function relationships to early adolescent e-cigarette use: a substance use pathway? Addict Behav (2014) 1.15

The enigmatic persistence of anorexia nervosa. Am J Psychiatry (2013) 1.15

Enhanced behavioral response to repeated-dose cocaine in adolescent rats. Psychopharmacology (Berl) (2005) 1.14

Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior. J Neurosci (2012) 1.14

Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. Behav Brain Res (2008) 1.14

Tract-Based Spatial Statistics (TBSS) of diffusion tensor imaging data in alcohol dependence: abnormalities of the motivational neurocircuitry. Psychiatry Res (2009) 1.13

Differential developmental trajectories for CB1 cannabinoid receptor expression in limbic/associative and sensorimotor cortical areas. Synapse (2011) 1.13

The neurobiology of adolescence: changes in brain architecture, functional dynamics, and behavioral tendencies. Neurosci Biobehav Rev (2011) 1.13

Refinements in the hierarchical structure of externalizing psychiatric disorders: Patterns of lifetime liability from mid-adolescence through early adulthood. J Abnorm Psychol (2009) 1.13

Age-related influence of contingencies on a saccade task. Exp Brain Res (2006) 1.13

Adaptive plasticity of NMDA receptors and dendritic spines: implications for enhanced vulnerability of the adolescent brain to alcohol addiction. Pharmacol Biochem Behav (2007) 1.13

Trends in the disapproval and use of marijuana among adolescents and young adults in the United States: 2002-2013. Am J Drug Alcohol Abuse (2015) 1.12

Reinstatement of cocaine seeking induced by drugs, cues, and stress in adolescent and adult rats. Psychopharmacology (Berl) (2009) 1.12

Distinctions in Behavioral Impulsivity: Implications for Substance Abuse Research. Addict Disord Their Treat (2009) 1.12

Bipolar spectrum-substance use co-occurrence: Behavioral approach system (BAS) sensitivity and impulsiveness as shared personality vulnerabilities. J Pers Soc Psychol (2009) 1.11

Meaningful family relationships: neurocognitive buffers of adolescent risk taking. J Cogn Neurosci (2012) 1.11

Does adolescent risk taking imply weak executive function? A prospective study of relations between working memory performance, impulsivity, and risk taking in early adolescence. Dev Sci (2011) 1.11

Arg kinase regulates prefrontal dendritic spine refinement and cocaine-induced plasticity. J Neurosci (2012) 1.11

Neural correlates of sexual cue reactivity in individuals with and without compulsive sexual behaviours. PLoS One (2014) 1.10

Developmental changes in brain function underlying the influence of reward processing on inhibitory control. Dev Cogn Neurosci (2011) 1.10

Health/functioning characteristics, gambling behaviors, and gambling-related motivations in adolescents stratified by gambling problem severity: findings from a high school survey. Am J Addict (2011) 1.09

Impact of socio-emotional context, brain development, and pubertal maturation on adolescent risk-taking. Horm Behav (2013) 1.08

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Arch Gen Psychiatry (2012) 1.08

Articles cited by this

(truncated to the top 100)

The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev (1993) 19.60

Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAMA (1990) 17.70

The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev (2000) 17.59

Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory. Psychol Rev (1995) 11.39

Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli. Psychopharmacology (Berl) (1999) 7.06

Varieties of impulsivity. Psychopharmacology (Berl) (1999) 6.86

Stages of progression in drug involvement from adolescence to adulthood: further evidence for the gateway theory. J Stud Alcohol (1992) 6.71

Synaptic density in human frontal cortex - developmental changes and effects of aging. Brain Res (1979) 6.68

Functional imaging of neural responses to expectancy and experience of monetary gains and losses. Neuron (2001) 6.44

Psychiatric aspects of impulsivity. Am J Psychiatry (2001) 6.13

Dopamine responses comply with basic assumptions of formal learning theory. Nature (2001) 5.57

Reduced prefrontal gray matter volume and reduced autonomic activity in antisocial personality disorder. Arch Gen Psychiatry (2000) 5.26

Quantitative magnetic resonance imaging of human brain development: ages 4-18. Cereb Cortex (1996) 5.08

Positron emission tomography study of human brain functional development. Ann Neurol (1987) 4.89

Structural maturation of neural pathways in children and adolescents: in vivo study. Science (1999) 4.78

Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers. Neuropsychologia (2001) 4.71

Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cereb Cortex (2000) 4.61

Addiction and the brain: the neurobiology of compulsion and its persistence. Nat Rev Neurosci (2001) 4.58

Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence? J Psychiatr Res (1984) 4.28

Prevalence and correlates of alcohol use and DSM-IV alcohol dependence in the United States: results of the National Longitudinal Alcohol Epidemiologic Survey. J Stud Alcohol (1997) 3.93

Nicotine dependence in the United States: prevalence, trends, and smoking persistence. Arch Gen Psychiatry (2001) 3.82

Prevalence and demographic correlates of symptoms of last year dependence on alcohol, nicotine, marijuana and cocaine in the U.S. population. Drug Alcohol Depend (1997) 3.61

Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: evidence for monoaminergic mechanisms. Neuropsychopharmacology (1999) 3.60

From first drug use to drug dependence; developmental periods of risk for dependence upon marijuana, cocaine, and alcohol. Neuropsychopharmacology (2002) 3.56

Excessive discounting of delayed rewards in substance abusers with gambling problems. Drug Alcohol Depend (1999) 3.56

Development of inhibitory control across the life span. Dev Psychol (1999) 3.54

Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. Eur J Neurosci (1999) 3.54

Cerebral hemisphere regulation of motivated behavior. Brain Res (2000) 3.53

Responses of monkey dopamine neurons during learning of behavioral reactions. J Neurophysiol (1992) 3.46

Early-onset drug use and risk of later drug problems. Drug Alcohol Depend (1995) 3.42

The return of Phineas Gage: clues about the brain from the skull of a famous patient. Science (1994) 3.40

Evidence for striatal dopamine release during a video game. Nature (1998) 3.28

Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients. Biol Psychiatry (2002) 3.22

Convergence and segregation of ventral striatal inputs and outputs. Ann N Y Acad Sci (1999) 3.18

The nucleus accumbens as a complex of functionally distinct neuronal ensembles: an integration of behavioural, electrophysiological and anatomical data. Prog Neurobiol (1994) 3.10

Effect of the age at which smoking begins on frequency of smoking in adulthood. N Engl J Med (1991) 2.96

Psychomotor stimulant addiction: a neural systems perspective. J Neurosci (2002) 2.83

Prevalence and correlates of drug use and dependence in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry (1995) 2.74

Extent of smoking and nicotine dependence in the United States: 1991-1993. Nicotine Tob Res (2000) 2.69

DeltaFosB: a sustained molecular switch for addiction. Proc Natl Acad Sci U S A (2001) 2.64

A neurobiological basis for substance abuse comorbidity in schizophrenia. Biol Psychiatry (2001) 2.58

Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats. Dev Psychobiol (1983) 2.57

BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses. Neuron (1998) 2.55

Repetitive transcranial magnetic stimulation of the human prefrontal cortex induces dopamine release in the caudate nucleus. J Neurosci (2001) 2.49

Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue. J Neurosci (2002) 2.49

Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. J Neurosci (1999) 2.36

Investigating the neurocognitive deficits associated with chronic drug misuse. Curr Opin Neurobiol (2001) 2.27

Predictors of adolescent psychopathy: the role of impulsivity, hyperactivity, and sensation seeking. J Am Acad Psychiatry Law (2001) 2.10

Neurotransmitter regulation of dopamine neurons in the ventral tegmental area. Brain Res Brain Res Rev (1993) 2.00

Are adolescents the victims of raging hormones: evidence for activational effects of hormones on moods and behavior at adolescence. Psychol Bull (1992) 1.90

Psychobiological risk factors for vulnerability to psychostimulants in human adolescents and animal models. Neurosci Biobehav Rev (1999) 1.90

Pharmacotherapy of attention-deficit/hyperactivity disorder reduces risk for substance use disorder. Pediatrics (1999) 1.88

Elevated novelty seeking and peculiar d-amphetamine sensitization in periadolescent mice compared with adult mice. Behav Neurosci (1998) 1.68

Neuropsychiatric sequelae of head injuries. Psychiatr Clin North Am (1992) 1.67

Synaptic economics: competition and cooperation in synaptic plasticity. Neuron (1996) 1.63

Synchronous development of pyramidal neuron dendritic spines and parvalbumin-immunoreactive chandelier neuron axon terminals in layer III of monkey prefrontal cortex. Neuroscience (1995) 1.55

Individual risk factors for adolescent substance use. Drug Alcohol Depend (1999) 1.54

Relapse to drug-seeking: neural and molecular mechanisms. Drug Alcohol Depend (1998) 1.53

Development of the prefrontal cortex during adolescence: insights into vulnerable neural circuits in schizophrenia. Neuropsychopharmacology (1997) 1.48

Smaller volume of prefrontal lobe in polysubstance abusers: a magnetic resonance imaging study. Neuropsychopharmacology (1998) 1.46

Neurobiology of decision-making: risk and reward. Semin Clin Neuropsychiatry (2001) 1.44

Epidemiology of tobacco use among US adolescents. Nicotine Tob Res (1999) 1.44

Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and medial prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions of D-amphetamine. Behav Brain Res (1993) 1.42

Cocaine self-administration increases the incentive motivational properties of the drug in rats. Eur J Neurosci (1999) 1.41

CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry (1994) 1.41

Neurophysiology of converging synaptic inputs from the rat prefrontal cortex, amygdala, midline thalamus, and hippocampal formation onto single neurons of the caudate/putamen and nucleus accumbens. Hippocampus (1996) 1.41

Effects of medial prefrontal or anterior cingulate cortex lesions on responding for cocaine under fixed-ratio and second-order schedules of reinforcement in rats. Psychopharmacology (Berl) (1997) 1.40

Frontal dysfunction in neurologically normal chronic alcoholic subjects: metabolic and neuropsychological findings. Psychol Med (1998) 1.38

Associations between ADHD and psychoactive substance use disorders. Findings from a longitudinal study of high-risk siblings of ADHD children. Am J Addict (1997) 1.37

Cocaine sensitization in periadolescent and adult rats. J Pharmacol Exp Ther (1995) 1.36

Repeated intermittent administration of psychomotor stimulant drugs alters the acquisition of Pavlovian approach behavior in rats: differential effects of cocaine, d-amphetamine and 3,4- methylenedioxymethamphetamine ("Ecstasy"). Biol Psychiatry (2001) 1.34

Modulation of cell firing in the nucleus accumbens. Ann N Y Acad Sci (1999) 1.33

Repetitive and compulsive behavior in frontal lobe degenerations. J Neuropsychiatry Clin Neurosci (1994) 1.33

Age-related variations in evoked potentials to auditory stimuli in normal human subjects. Electroencephalogr Clin Neurophysiol (1978) 1.32

Differential postnatal development of catecholamine and serotonin inputs to identified neurons in prefrontal cortex of rhesus monkey. J Neurosci (2000) 1.28

Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: an animal model of dual diagnosis schizophrenia. Neuropsychopharmacology (2002) 1.26

Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats. Pharmacol Biochem Behav (2001) 1.25

Novelty-evoked elevations of nucleus accumbens dopamine: dependence on impulse flow from the ventral subiculum and glutamatergic neurotransmission in the ventral tegmental area. Eur J Neurosci (2001) 1.25

Acquisition of i.v. amphetamine and cocaine self-administration in rats as a function of dose. Psychopharmacology (Berl) (1997) 1.24

Frontal-subcortical circuits: the anatomic basis of executive, social and motivated behaviors. J Psychopharmacol (1997) 1.21

Peripubertal refinement of the intrinsic and associational circuitry in monkey prefrontal cortex. Neuroscience (1997) 1.20

Prior stimulant treatment in adolescents with bipolar disorder: association with age at onset. Bipolar Disord (2001) 1.14

Estrogen is more than just a "sex hormone": novel sites for estrogen action in the hippocampus and cerebral cortex. Front Neuroendocrinol (2000) 1.14

Integrity of the mesocortical dopaminergic system is necessary for complete expression of in vivo hippocampal-prefrontal cortex long-term potentiation. Neuroscience (1999) 1.13

Pathological gambling: addiction or compulsion? Semin Clin Neuropsychiatry (2001) 1.13

The effects of methylenedioxymethamphetamine (MDMA, "Ecstasy") on monoaminergic neurotransmission in the central nervous system. Prog Neurobiol (1996) 1.11

Segregation and convergence of information flow through the cortico-subthalamic pathways. J Neurosci (2001) 1.11

Stimulation-induced [14C]2-deoxyglucose labeling of synaptic activity in the central auditory system. J Comp Neurol (1986) 1.09

Is substance abuse in schizophrenia related to impulsivity, sensation seeking, or anhedonia? Am J Psychiatry (2001) 1.09

The effects of stress on central dopaminergic neurons: possible clinical implications. Neurochem Res (1997) 1.09

Role for dopamine in the behavioral functions of the prefrontal corticostriatal system: implications for mental disorders and psychotropic drug action. Prog Brain Res (2000) 1.07

The relationship between substance use disorders, impulse control disorders, and pathological aggression. Am J Addict (1998) 1.06

Neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. Neuroscience (2000) 1.02

Human cerebral blood flow and oxygen consumption as related to aging. Res Publ Assoc Res Nerv Ment Dis (1956) 1.02

The neurobiology of pathological gambling. Semin Clin Neuropsychiatry (2001) 1.02

Effect of 6-hydroxydopamine lesions of the medial prefrontal cortex on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement. Pharmacol Biochem Behav (1996) 1.02

CSF serotonin metabolite (5-HIAA) studies in depression, impulsivity, and violence. J Clin Psychiatry (1990) 1.00

Altered CSF 5-HIAA Disposition in Pathologic Male Gamblers. CNS Spectr (1999) 1.00

Endocrinology in preadolescents and adolescents. I. Hormonal changes during normal puberty. Am J Dis Child (1978) 0.99

Prevalence of use, abuse and dependence of illicit drugs among adolescents and young adults in a community sample. Eur Addict Res (1998) 0.98

Articles by these authors

(truncated to the top 100)

Can food be addictive? Public health and policy implications. Addiction (2011) 6.27

Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients. Arch Neurol (2010) 4.77

Behavioral impulsivity predicts treatment outcome in a smoking cessation program for adolescent smokers. Drug Alcohol Depend (2006) 3.61

Molecular mechanisms of memory reconsolidation. Nat Rev Neurosci (2007) 3.52

Compulsive features in behavioural addictions: the case of pathological gambling. Addiction (2011) 3.28

Introduction to behavioral addictions. Am J Drug Alcohol Abuse (2010) 3.22

Association of dopamine agonist use with impulse control disorders in Parkinson disease. Arch Neurol (2006) 3.02

Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review. Neuropsychopharmacology (2009) 2.60

Mindfulness-based treatments for co-occurring depression and substance use disorders: what can we learn from the brain? Addiction (2010) 2.50

Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling. Am J Psychiatry (2006) 2.50

Preliminary validity and reliability testing of a structured clinical interview for pathological gambling. Psychiatry Res (2004) 2.35

Cue-induced brain activity changes and relapse in cocaine-dependent patients. Neuropsychopharmacology (2006) 2.32

DeltaFosB in the nucleus accumbens regulates food-reinforced instrumental behavior and motivation. J Neurosci (2006) 2.29

The neurobiology and genetics of impulse control disorders: relationships to drug addictions. Biochem Pharmacol (2007) 2.22

Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors. Biol Psychiatry (2010) 2.16

Impairments of reversal learning and response perseveration after repeated, intermittent cocaine administrations to monkeys. Neuropsychopharmacology (2002) 2.13

Broadening our horizon: response to commentaries. Addiction (2012) 2.11

Impulse control disorders in adult psychiatric inpatients. Am J Psychiatry (2005) 2.09

Health correlates of recreational gambling in older adults. Am J Psychiatry (2004) 2.08

Pretreatment brain activation during stroop task is associated with outcomes in cocaine-dependent patients. Biol Psychiatry (2008) 2.04

Gender differences in the associations between past-year gambling problems and psychiatric disorders. Soc Psychiatry Psychiatr Epidemiol (2007) 2.02

Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression. Biol Psychiatry (2007) 2.01

Bidirectional behavioral plasticity of memory reconsolidation depends on amygdalar protein kinase A. Nat Neurosci (2006) 1.96

Chronic unpredictable stress decreases cell proliferation in the cerebral cortex of the adult rat. Biol Psychiatry (2007) 1.94

Investigating the behavioral and self-report constructs of impulsivity domains using principal component analysis. Behav Pharmacol (2009) 1.90

Validation of the questionnaire for impulsive-compulsive disorders in Parkinson's disease. Mov Disord (2009) 1.89

Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity. Psychopharmacology (Berl) (2011) 1.77

Amantadine use associated with impulse control disorders in Parkinson disease in cross-sectional study. Ann Neurol (2010) 1.77

Problematic Internet use: clinical implications. CNS Spectr (2007) 1.74

Impulse control disorders in Parkinson disease: a multicenter case--control study. Ann Neurol (2011) 1.73

An FMRI study of the effects of psychostimulants on default-mode processing during Stroop task performance in youths with ADHD. Am J Psychiatry (2009) 1.70

Psychiatric correlates of gambling in adolescents and young adults grouped by age at gambling onset. Arch Gen Psychiatry (2004) 1.68

Insight into the relationship between impulsivity and substance abuse from studies using animal models. Alcohol Clin Exp Res (2010) 1.62

Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study. Subst Abus (2009) 1.62

Impulsive choice and response in dopamine agonist-related impulse control behaviors. Psychopharmacology (Berl) (2009) 1.62

The neurobiology of substance and behavioral addictions. CNS Spectr (2006) 1.59

Neurodevelopment, impulsivity, and adolescent gambling. J Gambl Stud (2003) 1.57

Video-gaming among high school students: health correlates, gender differences, and problematic gaming. Pediatrics (2010) 1.56

Nicotine enhances responding with conditioned reinforcement. Psychopharmacology (Berl) (2003) 1.52

A history of corticosterone exposure regulates fear extinction and cortical NR2B, GluR2/3, and BDNF. Neuropsychopharmacology (2008) 1.51

Gender differences in adolescent gambling. Ann Clin Psychiatry (2006) 1.51

The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala. Biol Psychiatry (2006) 1.51

An initial study of neural responses to monetary incentives as related to treatment outcome in cocaine dependence. Biol Psychiatry (2011) 1.50

Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability. J Neurosci (2007) 1.49

A placebo-controlled trial of bupropion combined with nicotine patch for smoking cessation in schizophrenia. Biol Psychiatry (2007) 1.48

Bidirectional modulation of goal-directed actions by prefrontal cortical dopamine. Cereb Cortex (2007) 1.46

Shared brain vulnerabilities open the way for nonsubstance addictions: carving addiction at a new joint? Ann N Y Acad Sci (2010) 1.46

The Gambling Symptom Assessment Scale (G-SAS): a reliability and validity study. Psychiatry Res (2009) 1.46

Diminished frontostriatal activity during processing of monetary rewards and losses in pathological gambling. Biol Psychiatry (2012) 1.44

Stealing among high school students: prevalence and clinical correlates. J Am Acad Psychiatry Law (2011) 1.43

Gender differences in adolescent marijuana use and associated psychosocial characteristics. J Addict Med (2011) 1.42

The fragrant power of collective fear. PLoS One (2015) 1.39

beta2-Subunit-containing nicotinic acetylcholine receptors are involved in nicotine-induced increases in conditioned reinforcement but not progressive ratio responding for food in C57BL/6 mice. Psychopharmacology (Berl) (2005) 1.38

Compulsive aspects of impulse-control disorders. Psychiatr Clin North Am (2006) 1.37

Acute hippocampal brain-derived neurotrophic factor restores motivational and forced swim performance after corticosterone. Biol Psychiatry (2008) 1.37

A targeted review of the neurobiology and genetics of behavioural addictions: an emerging area of research. Can J Psychiatry (2013) 1.37

Simulated apoptosis/neurogenesis regulates learning and memory capabilities of adaptive neural networks. Neuropsychopharmacology (2004) 1.36

Medication-related impulse control and repetitive behaviors in Parkinson's disease. Curr Opin Neurol (2007) 1.35

Inhibition of Rho via Arg and p190RhoGAP in the postnatal mouse hippocampus regulates dendritic spine maturation, synapse and dendrite stability, and behavior. J Neurosci (2007) 1.33

The drive to eat: comparisons and distinctions between mechanisms of food reward and drug addiction. Nat Neurosci (2012) 1.33

Binge eating disorder and food addiction. Curr Drug Abuse Rev (2011) 1.33

Impulse-control disorders in adolescent psychiatric inpatients: co-occurring disorders and sex differences. J Clin Psychiatry (2007) 1.33

Neural correlates of stress- and food cue-induced food craving in obesity: association with insulin levels. Diabetes Care (2012) 1.32

Hypocretin and nicotine excite the same thalamocortical synapses in prefrontal cortex: correlation with improved attention in rat. J Neurosci (2005) 1.31

Sex chromosome complement regulates habit formation. Nat Neurosci (2007) 1.31

D-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens. J Neurosci (2010) 1.30

Memantine shows promise in reducing gambling severity and cognitive inflexibility in pathological gambling: a pilot study. Psychopharmacology (Berl) (2010) 1.29

Sex differences in the behavioral effects of 24-h/day access to cocaine under a discrete trial procedure. Neuropsychopharmacology (2004) 1.29

Impulsive sensation seeking, parental history of alcohol problems, and current alcohol and tobacco use in adolescents. J Addict Med (2008) 1.28

Prenatal cocaine exposure and gray matter volume in adolescent boys and girls: relationship to substance use initiation. Biol Psychiatry (2013) 1.27

Long-term follow-up of impulse control disorders in Parkinson's disease. Mov Disord (2008) 1.27

Neuronal correlates of instrumental learning in the dorsal striatum. J Neurophysiol (2009) 1.26

Weight gain associated with atypical antipsychotic use in children and adolescents: prevalence, clinical relevance, and management. Paediatr Drugs (2004) 1.26

Paroxetine treatment of pathological gambling: a multi-centre randomized controlled trial. Int Clin Psychopharmacol (2003) 1.25

Decreased ventral striatal activity with impulse control disorders in Parkinson's disease. Mov Disord (2010) 1.22

Nicotinic acetylcholine receptors in the ventral tegmental area mediate the dopamine activating and reinforcing properties of ethanol cues. Psychopharmacology (Berl) (2007) 1.22

To do or not to do? The complexities of addiction, motivation, self-control, and impulsivity. Am J Psychiatry (2007) 1.21

Orexin signaling via the orexin 1 receptor mediates operant responding for food reinforcement. Biol Psychiatry (2010) 1.21

Repeated nicotine exposure enhances responding with conditioned reinforcement. Psychopharmacology (Berl) (2004) 1.21

Why do delusions persist? Front Hum Neurosci (2009) 1.20

Protein kinase A as a therapeutic target for memory disorders: rationale and challenges. Trends Mol Med (2005) 1.20

Problematic Internet use and health in adolescents: data from a high school survey in Connecticut. J Clin Psychiatry (2011) 1.20

Dissociable regulation of instrumental action within mouse prefrontal cortex. Eur J Neurosci (2010) 1.19

Aberrant learning and memory in addiction. Neurobiol Learn Mem (2011) 1.19

Tossing the baby out with the bathwater after a brief rinse? The potential downside of dismissing food addiction based on limited data. Nat Rev Neurosci (2012) 1.19

Monetary reward processing in obese individuals with and without binge eating disorder. Biol Psychiatry (2013) 1.19

Self-reported gambling-related suicidality among gambling helpline callers. Psychol Addict Behav (2005) 1.19

Stress and disease: is being female a predisposing factor? J Neurosci (2007) 1.18

A preliminary study of the neural effects of behavioral therapy for substance use disorders. Drug Alcohol Depend (2011) 1.18

Blockade of melanocortin transmission inhibits cocaine reward. Eur J Neurosci (2005) 1.17

Predicting response to opiate antagonists and placebo in the treatment of pathological gambling. Psychopharmacology (Berl) (2008) 1.16

Gambling, health and age: data from the National Epidemiologic Survey on Alcohol and Related Conditions. Psychol Addict Behav (2007) 1.16

Repeated nicotine exposure enhances reward-related learning in the rat. Neuropsychopharmacology (2003) 1.16

Reconsolidation of a cocaine-associated stimulus requires amygdalar protein kinase A. J Neurosci (2010) 1.15

A pilot study of impulsivity and compulsivity in pathological gambling. Psychiatry Res (2009) 1.15

Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior. J Neurosci (2012) 1.14

Association of posttraumatic stress disorder with reduced in vivo norepinephrine transporter availability in the locus coeruleus. JAMA Psychiatry (2013) 1.14

Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice. J Neurosci (2004) 1.13

Dissociation of genetic and hormonal influences on sex differences in alcoholism-related behaviors. J Neurosci (2010) 1.12

Smoking expectancies, weight concerns, and dietary behaviors in adolescence. Pediatrics (2010) 1.12