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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 1992 5.04
2 VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells. Am J Physiol 1998 2.71
3 Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer. J Natl Cancer Inst 1998 2.50
4 Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium. Am J Physiol 1996 2.46
5 Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase1/2 activation in postcapillary endothelium. J Biol Chem 1998 2.11
6 Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells. J Natl Cancer Inst 1995 2.07
7 A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases. EMBO J 1999 1.89
8 Role of prostaglandin E1 and copper in angiogenesis. J Natl Cancer Inst 1982 1.85
9 Induction of inflammatory angiogenesis by monocyte chemoattractant protein-1. Int J Cancer 1999 1.79
10 An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis. Cancer Res 1997 1.63
11 Interleukin 1 is an autocrine regulator of human endothelial cell growth. Proc Natl Acad Sci U S A 1990 1.57
12 c-fos-induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro. Proc Natl Acad Sci U S A 1999 1.49
13 The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo. Br J Cancer 2000 1.33
14 In vitro and in vivo activation of endothelial cells by colony-stimulating factors. J Clin Invest 1991 1.31
15 Ceruloplasmin, copper ions, and angiogenesis. J Natl Cancer Inst 1982 1.29
16 HIV-tat protein is a heparin-binding angiogenic growth factor. Oncogene 1996 1.18
17 Role of soluble mediators in angiogenesis. Eur J Cancer 1996 1.17
18 The heparin binding 25 kDa fragment of thrombospondin-1 promotes angiogenesis and modulates gelatinase and TIMP-2 production in endothelial cells. FASEB J 2000 1.12
19 B1 receptor involvement in the effect of bradykinin on venular endothelial cell proliferation and potentiation of FGF-2 effects. Br J Pharmacol 1998 1.07
20 Interaction of urokinase with specific receptors stimulates mobilization of bovine adrenal capillary endothelial cells. Exp Cell Res 1988 1.06
21 The activin-binding protein follistatin regulates autocrine endothelial cell activity and induces angiogenesis. Lab Invest 1997 1.03
22 The bradykinin/B1 receptor promotes angiogenesis by up-regulation of endogenous FGF-2 in endothelium via the nitric oxide synthase pathway. FASEB J 2001 1.01
23 I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo. Blood 2000 1.01
24 Inhibitory effect of full-length human endostatin on in vitro angiogenesis. Biochem Biophys Res Commun 1999 1.01
25 Chronic viral hepatitis induced by hepatitis C but not hepatitis B virus infection correlates with increased liver angiogenesis. Hepatology 1997 1.00
26 Proliferation and migration of endothelial cells is promoted by endothelins via activation of ETB receptors. Am J Physiol 1995 0.99
27 Soluble N-cadherin fragment promotes angiogenesis. Clin Exp Metastasis 2006 0.99
28 The tachykinin NK1 receptor mediates the migration-promoting effect of substance P on human skin fibroblasts in culture. Naunyn Schmiedebergs Arch Pharmacol 1996 0.98
29 Abolished angiogenicity and tumorigenicity of Burkitt lymphoma by interleukin-10. Blood 2000 0.98
30 Cell-mediated delivery of fibroblast growth factor-2 and vascular endothelial growth factor onto the chick chorioallantoic membrane: endothelial fenestration and angiogenesis. J Vasc Res 2001 0.97
31 Angiogenesis and neoplastic progression in vitro. J Natl Cancer Inst 1982 0.94
32 Urokinase-dependent angiogenesis in vitro and diacylglycerol production are blocked by antisense oligonucleotides against the urokinase receptor. Lab Invest 1998 0.92
33 FGF-2 overexpression opposes the beta amyloid toxic injuries to the vascular endothelium. Cell Death Differ 2006 0.91
34 Interaction of fibroblast growth factor-2 (FGF-2) with free gangliosides: biochemical characterization and biological consequences in endothelial cell cultures. Mol Biol Cell 1999 0.90
35 Basic fibroblast growth factor overexpression in endothelial cells: an autocrine mechanism for angiogenesis and angioproliferative diseases. Cell Growth Differ 1996 0.89
36 Activation of MAPKs in proximal tubule cells from spontaneously hypertensive and control Wistar-Kyoto rats. Hypertension 2000 0.89
37 Growth advantage and vascularization induced by basic fibroblast growth factor overexpression in endometrial HEC-1-B cells: an export-dependent mechanism of action. Cancer Res 1995 0.88
38 Quantitative RT-PCR assay for VEGF mRNA in human tumors of the kidney. Int J Biol Markers 2000 0.87
39 Antiangiogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers. Br J Cancer 2003 0.87
40 Exogenous BH4/Bcl-2 peptide reverts coronary endothelial cell apoptosis induced by oxidative stress. J Vasc Res 2004 0.86
41 Interaction of high-molecular-weight basic fibroblast growth factor with endothelium: biological activity and intracellular fate of human recombinant M(r) 24,000 bFGF. J Cell Physiol 1994 0.85
42 Purine analogue 6-methylmercaptopurine riboside inhibits early and late phases of the angiogenesis process. Cancer Res 1999 0.85
43 Interferon-alpha and interleukin 2 synergistically enhance basic fibroblast growth factor synthesis and induce release, promoting endothelial cell growth. J Clin Invest 1993 0.85
44 Plasminogen activators (urokinase) mediate neovascularization: possible role in tumor angiogenesis. Semin Thromb Hemost 1986 0.83
45 Distinct capillary density and progression promoted by vascular endothelial growth factor-A homodimers and heterodimers. Angiogenesis 1997 0.82
46 EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity. Oncogene 2011 0.82
47 Endothelial cell migration is induced by soluble P-selectin. Life Sci 1998 0.81
48 The effect of linomide on the migration and the proliferation of capillary endothelial cells elicited by vascular endothelial growth factor. Br J Pharmacol 1996 0.81
49 Effects of cortisone with and without heparin on angiogenesis induced by prostaglandin E1 and by S180 cells, and on growth of murine transplantable tumours. Int J Cancer 1985 0.81
50 TAT-BH4 counteracts Abeta toxicity on capillary endothelium. FEBS Lett 2007 0.80
51 Distinct chemotactic and angiogenic activities of peptides derived from Kaposi's sarcoma virus encoded chemokines. Int J Oncol 2000 0.80
52 Synergism between gangliosides and basic fibroblastic growth factor in favouring survival, growth, and motility of capillary endothelium. J Cell Physiol 1990 0.79
53 Nitric oxide modulates the angiogenic phenotype of middle-T transformed endothelial cells. Int J Biochem Cell Biol 2001 0.79
54 Endostatin: a promising drug for antiangiogenic therapy. Int J Biol Markers 2000 0.78
55 Molecular and cellular basis of myocardial angiogenesis. Cell Mol Biol Res 1994 0.78
56 Growth and motility of microvascular endothelium are modulated by the relative concentration of gangliosides in the medium. J Cell Physiol 1992 0.78
57 Cooperation of heparin with other angiogenetic effectors. Int J Tissue React 1986 0.78
58 ANG II potentiates mitogenic effect of norepinephrine in vascular muscle cells: role of FGF-2. Am J Physiol Heart Circ Physiol 2001 0.77
59 [An angiogenesis study of Dukes' B colonic tumors]. Clin Ter 2000 0.77
60 Calcitonin gene-related peptide selectively increases cAMP levels in the guinea-pig ureter. Eur J Pharmacol 1995 0.77
61 Cu(II) and Zn(II) complexes with hyaluronic acid and its sulphated derivative. Effect on the motility of vascular endothelial cells. J Inorg Biochem 2000 0.77
62 Gangliosides, copper ions and angiogenic capacity of adult tissues. Cancer Metastasis Rev 1990 0.77
63 Vasorelaxant effects induced by the antiangiogenic drug linomide in aortic and saphenous vein preparations of the rabbit. Br J Pharmacol 1997 0.77
64 Cardiovascular effects of capsaicin-sensitive neurons. Cardioscience 1993 0.76
65 The effect of thiorphan on release of sensory neuropeptides from guinea-pig cerebral venous sinuses. Pharmacol Res 1991 0.76
66 The biological basis for antiangiogenic therapy. Eur J Cancer 2000 0.76
67 Differential contribution of bradykinin receptors in angiogenesis. Adv Exp Med Biol 2000 0.76
68 Angiogenesis. Exp Nephrol 1996 0.76
69 Pyridoxamine as inhibitor of the blood plasma benzylamine oxidase and other copper-containing amine oxidases. J Pharm Pharmacol 1985 0.75
70 Thapsigargin inhibits the response to acetylcholine and substance P but does not interfere with the responses to endothelium-independent agents. J Cardiovasc Pharmacol 1996 0.75
71 Influence of lithium on mammary tumor growth in vivo. Cancer Lett 1980 0.75
72 Angiogenesis and prediction of sarcoma formation by plastic. Cancer Res 1981 0.75
73 [Coronary angiogenesis: role, modulation and prospects]. G Ital Cardiol 1994 0.75
74 Biology and physiopathology of angiogenesis: the 1997 Philippe Laudat Conference. Angiogenesis 1998 0.75
75 Activity of "NO-donor" or "NO-mediated" drugs. Monaldi Arch Chest Dis 2001 0.75
76 Angiogenic phenotype induced by basic fibroblast growth factor transfection in brain microvascular endothelial cells. Int J Oncol 1996 0.75
77 A nanoscale fluorocarbon coating on PET surfaces improves the adhesion and growth of cultured coronary endothelial cells. Nanotechnology 2008 0.75
78 Effect of selective tachykinin receptor antagonists on the growth of human skin fibroblasts. Neuropeptides 1993 0.75