PubRank

S V Tavtigian

Author PubWeight™ 80.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997 15.38
2 A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994 13.00
3 A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes. Nat Genet 1996 4.38
4 Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor. Cancer Res 1997 3.55
5 RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2. J Biol Chem 1997 3.26
6 BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res 2000 3.01
7 BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing. JAMA 1997 2.78
8 BRCA2 germline mutations in male breast cancer cases and breast cancer families. Nat Genet 1996 2.75
9 Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation. J Med Genet 2004 2.40
10 Rare mutations in XRCC2 increase the risk of breast cancer. Am J Hum Genet 2012 2.06
11 Characterization of a carboxy-terminal BRCA1 interacting protein. Oncogene 1998 1.94
12 Complex structure and regulation of the P16 (MTS1) locus. Cancer Res 1995 1.87
13 Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. Cancer Res 1998 1.83
14 Low incidence of BRCA2 mutations in breast carcinoma and other cancers. Nat Genet 1996 1.74
15 Classification of BRCA1 missense variants of unknown clinical significance. J Med Genet 2005 1.71
16 Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding. Cancer Res 2000 1.60
17 Prostate cancer susceptibility genes: lessons learned and challenges posed. Endocr Relat Cancer 2003 1.44
18 The role of MMAC1 mutations in early-onset breast cancer: causative in association with Cowden syndrome and excluded in BRCA1-negative cases. Am J Hum Genet 1997 1.37
19 Interpreting epidemiological research: blinded comparison of methods used to estimate the prevalence of inherited mutations in BRCA1. J Med Genet 2001 1.26
20 Genetic, functional, and histopathological evaluation of two C-terminal BRCA1 missense variants. J Med Genet 2005 1.25
21 Does nonsense-mediated mRNA decay explain the ovarian cancer cluster region of the BRCA2 gene? Oncogene 2006 1.23
22 HPC2 variants and screen-detected prostate cancer. Am J Hum Genet 2001 1.20
23 Genomic structure, expression and mutational analysis of the P15 (MTS2) gene. Oncogene 1995 1.12
24 Microsatellite deletion mapping on chromosome 10q and mutation analysis of MMAC1, FAS, and MXI1 in human glioblastoma multiforme. Int J Oncol 1998 1.02
25 Prostate cancer susceptibility locus HPC1 in Utah high-risk pedigrees. Hum Mol Genet 1999 0.96
26 A Laboratory Information Management System (LIMS) for a high throughput genetic platform aimed at candidate gene mutation screening. Bioinformatics 2007 0.93
27 Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase. Oncogene 1999 0.89
28 Microdissection, DOP-PCR, and comparative genomic hybridization of paraffin-embedded familial prostate cancers. Cancer Genet Cytogenet 2000 0.83
29 Physical locus of the DNA polymerase gene and genetic maps of bacteriophage T5 mutants. J Virol 1985 0.83
30 Differential allelic expression in leukoblast from patients with acute myeloid leukemia suggests genetic regulation of CDA, DCK, NT5C2, NT5C3, and TP53. Drug Metab Dispos 2008 0.81
31 Localization of SMAD5 and its evaluation as a candidate myeloid tumor suppressor. Cancer Res 1997 0.81
32 Mutation analyses of 268 candidate genes in human tumor cell lines. Genomics 2001 0.80
33 Genomic structure, chromosomal location, and mutation analysis of the human CDC14A gene. Genomics 1999 0.79
34 Monitoring the efficacy of hybrid selection during positional cloning: the search for BRCA1. Mamm Genome 1995 0.77
35 Detection of BRCA1/2 mutations in breast cancer patients from Thailand and Pakistan. Clin Genet 2012 0.76
36 Localization of the VHR phosphatase gene and its analysis as a candidate for BRCA1. Genomics 1994 0.75