Manuela Battaglia

Author PubWeight™ 55.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol Rev 2006 6.08
2 Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat Rev Immunol 2007 4.55
3 Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J Exp Med 2002 3.49
4 Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. Immunity 2011 3.38
5 Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway. Blood 2010 2.15
6 Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412. Blood 2011 2.12
7 WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells. J Exp Med 2007 1.77
8 A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome. J Clin Invest 2007 1.67
9 STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells. Int Immunol 2008 1.58
10 Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice. Blood 2003 1.56
11 Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells. Diabetes 2008 1.49
12 Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice. Diabetes 2009 1.48
13 Generation of Donor-specific T Regulatory Type 1 Cells From Patients on Dialysis for Cell Therapy After Kidney Transplantation. Transplantation 2015 1.44
14 Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes. Diabetes 2011 1.39
15 Comment on M. Guillot-Delost et al. (2008;10:834-846): Clinical-grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene. J Gene Med 2009 1.39
16 Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells. Haematologica 2011 1.20
17 Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice. Diabetes 2009 1.18
18 Reduction of circulating neutrophils precedes and accompanies type 1 diabetes. Diabetes 2013 1.17
19 Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications. Curr Top Microbiol Immunol 2014 1.13
20 Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation. J Neuroimmunol 2010 1.08
21 Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplant. Diabetes 2009 1.08
22 Platelet factor 4 differentially modulates CD4+CD25+ (regulatory) versus CD4+CD25- (nonregulatory) T cells. J Immunol 2005 1.06
23 Calcineurin inhibitor-free immunosuppressive regimen in type 1 diabetes patients receiving islet transplantation: single-group phase 1/2 trial. Transplantation 2014 1.01
24 The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells. Blood 2007 0.93
25 Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation. PLoS One 2011 0.91
26 The role of interleukin 10 in the control of autoimmunity. J Autoimmun 2003 0.89
27 Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes. Adv Exp Med Biol 2010 0.89
28 Roles of the protein tyrosine phosphatase PTPN22 in immunity and autoimmunity. Clin Immunol 2013 0.89
29 Abnormalities of the Exocrine Pancreas in Type 1 Diabetes. Curr Diab Rep 2015 0.87
30 Allogeneic mesoangioblasts give rise to alpha-sarcoglycan expressing fibers when transplanted into dystrophic mice. Exp Cell Res 2006 0.87
31 Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice. PLoS One 2010 0.83
32 Relevance of hyperglycemia on the timing of functional loss of allogeneic islet transplants: implication for mouse model. Transplantation 2007 0.83
33 Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice. Diabetologia 2015 0.82
34 Re-establishing immune tolerance in type 1 diabetes via regulatory T cells. Novartis Found Symp 2008 0.80
35 Autoimmune diabetic patients undergoing allogeneic islet transplantation: are we ready for a regulatory T-cell therapy? Immunol Lett 2009 0.78
36 Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation. Curr Opin Hematol 2005 0.77
37 Standardization in flow cytometry: correct sample handling as a priority. Nat Rev Immunol 2012 0.75
38 All in (IL-) 1? Transplantation 2015 0.75