Published in Am J Physiol Lung Cell Mol Physiol on June 06, 2003
Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals. J Clin Invest (2006) 2.33
IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production. Am J Respir Cell Mol Biol (2006) 2.29
Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis. Am J Pathol (2005) 1.82
Interleukin-4, interleukin-13, signal transducer and activator of transcription factor 6, and allergic asthma. Curr Mol Med (2008) 1.64
Retracted Elevated IL-13Ralpha2 in intestinal epithelial cells from ulcerative colitis or colorectal cancer initiates MAPK pathway. Inflamm Bowel Dis (2010) 1.62
Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? Am J Physiol Lung Cell Mol Physiol (2008) 1.55
Regulation of airway mucin gene expression. Annu Rev Physiol (2008) 1.53
Influenza H5N1 and H1N1 virus replication and innate immune responses in bronchial epithelial cells are influenced by the state of differentiation. PLoS One (2010) 1.41
Epidermal growth factor receptor activation by epidermal growth factor mediates oxidant-induced goblet cell metaplasia in human airway epithelium. Am J Respir Cell Mol Biol (2006) 1.30
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. J Clin Invest (2012) 1.29
Host defenses against bacterial lower respiratory tract infection. Curr Opin Immunol (2012) 1.15
Advances in mucous cell metaplasia: a plug for mucus as a therapeutic focus in chronic airway disease. Am J Respir Cell Mol Biol (2009) 1.15
Differential regulation of MUC5AC/Muc5ac and hCLCA-1/mGob-5 expression in airway epithelium. Am J Respir Cell Mol Biol (2005) 1.10
Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epithelium. Am J Respir Cell Mol Biol (2010) 1.10
Chronic intermittent mechanical stress increases MUC5AC protein expression. Am J Respir Cell Mol Biol (2009) 1.09
Measurement of IL-13-induced iNOS-derived gas phase nitric oxide in human bronchial epithelial cells. Am J Respir Cell Mol Biol (2007) 1.05
Interleukin-13-induced MUC5AC is regulated by 15-lipoxygenase 1 pathway in human bronchial epithelial cells. Am J Respir Crit Care Med (2009) 1.05
IL-13 regulates cilia loss and foxj1 expression in human airway epithelium. Am J Respir Cell Mol Biol (2007) 1.04
MARCKS regulation of mucin secretion by airway epithelium in vitro: interaction with chaperones. Am J Respir Cell Mol Biol (2008) 0.98
Bidirectional virus secretion and nonciliated cell tropism following Andes virus infection of primary airway epithelial cell cultures. J Virol (2006) 0.98
Allergic sensitization: host-immune factors. Clin Transl Allergy (2014) 0.97
ERK/p44p42 mitogen-activated protein kinase mediates EGF-stimulated proliferation of conjunctival goblet cells in culture. Invest Ophthalmol Vis Sci (2008) 0.97
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity. Respir Res (2013) 0.96
Ciliated cells of pseudostratified airway epithelium do not become mucous cells after ovalbumin challenge. Am J Respir Cell Mol Biol (2012) 0.95
Directed Induction of Functional Multi-ciliated Cells in Proximal Airway Epithelial Spheroids from Human Pluripotent Stem Cells. Stem Cell Reports (2015) 0.92
STAT6 and lung inflammation. JAKSTAT (2013) 0.92
IL-13 induces a bronchial epithelial phenotype that is profibrotic. Respir Res (2008) 0.92
Absence of proteinase-activated receptor-1 signaling in mice confers protection from fMLP-induced goblet cell metaplasia. Am J Respir Cell Mol Biol (2009) 0.92
Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction. Proc Natl Acad Sci U S A (2004) 0.92
Mitogen-activated protein kinase signalling and ERK1/2 bistability in asthma. Clin Exp Allergy (2010) 0.91
Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye. Exp Eye Res (2013) 0.91
The Epithelial Cell in Lung Health and Emphysema Pathogenesis. Curr Respir Med Rev (2006) 0.90
IL-9 and IL-13 induce mucous cell metaplasia that is reduced by IFN-gamma in a Bax-mediated pathway. Am J Respir Cell Mol Biol (2007) 0.88
Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells. Respir Res (2012) 0.88
Phosphoinositide 3-kinase signalling in lung disease: leucocytes and beyond. Immunology (2007) 0.88
IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides. Respir Res (2011) 0.87
Influenza A virus infection of primary differentiated airway epithelial cell cultures derived from Syrian golden hamsters. Virology (2006) 0.87
Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo. J Allergy Clin Immunol (2012) 0.86
Putting the Squeeze on Airway Epithelia. Physiology (Bethesda) (2015) 0.86
Emerging molecular phenotypes of asthma. Am J Physiol Lung Cell Mol Physiol (2014) 0.85
Apoptosis and the airway epithelium. J Allergy (Cairo) (2011) 0.85
IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells. Clin Exp Allergy (2014) 0.84
Selective p38α mitogen-activated protein kinase inhibitor attenuates lung inflammation and fibrosis in IL-13 transgenic mouse model of asthma. J Asthma Allergy (2008) 0.84
P2Y2-receptor-mediated activation of a contralateral, lanthanide-sensitive calcium entry pathway in the human airway epithelium. Br J Pharmacol (2004) 0.83
The guinea-pig tracheal potential difference as an in vivo model for the study of epithelial sodium channel function in the airways. Br J Pharmacol (2008) 0.83
Murine cytomegalovirus influences Foxj1 expression, ciliogenesis, and mucus plugging in mice with allergic airway disease. Am J Pathol (2008) 0.83
HIV gp120 induces mucus formation in human bronchial epithelial cells through CXCR4/α7-nicotinic acetylcholine receptors. PLoS One (2013) 0.83
Characterization of a novel model incorporating airway epithelial damage and related fibrosis to the pathogenesis of asthma. Lab Invest (2014) 0.79
IL-17A induces Pendrin expression and chloride-bicarbonate exchange in human bronchial epithelial cells. PLoS One (2014) 0.79
Human leukocyte antigen-G expression in differentiated human airway epithelial cells: lack of modulation by Th2-associated cytokines. Respir Res (2013) 0.79
IL-31 does not induce normal human ciliated epithelial cells to differentiate into a phenotype consistent with the pathophysiology of asthma. Results Immunol (2012) 0.78
Rhythmic pressure waves induce mucin5AC expression via an EGFR-mediated signaling pathway in human airway epithelial cells. DNA Cell Biol (2013) 0.78
Epinephrine Activation of the β2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells. PLoS One (2015) 0.77
Immunogenetic programs for viral induction of mucous cell metaplasia. Am J Respir Cell Mol Biol (2006) 0.77
Secretory phospholipases A2 are secreted from ciliated cells and increase mucin and eicosanoid secretion from goblet cells. Chest (2015) 0.77
Dual p38/JNK mitogen activated protein kinase inhibitors prevent ozone-induced airway hyperreactivity in guinea pigs. PLoS One (2013) 0.76
Nasal epithelial cells can act as a physiological surrogate for paediatric asthma studies. PLoS One (2014) 0.76
Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas. Respir Res (2014) 0.76
Runx2 a novel regulator for goblet-cell differentiation and asthma development. FASEB J (2016) 0.75
An in vitro model of murine middle ear epithelium. Dis Model Mech (2016) 0.75
Lack of Platelet-Activating Factor Receptor Attenuates Experimental Food Allergy but Not Its Metabolic Alterations regarding Adipokine Levels. Biomed Res Int (2016) 0.75
Development of Combining of Human Bronchial Mucosa Models with XposeALI® for Exposure of Air Pollution Nanoparticles. PLoS One (2017) 0.75
Airway remodeling in asthma: what really matters. Cell Tissue Res (2017) 0.75
Clarithromycin suppresses CLCA1 and inhibits IL-13-Induced goblet cell hyperplasia in human bronchial epithelial cells. Antimicrob Agents Chemother (2016) 0.75
Phosphoinositide 3-Kinase in Asthma: Novel Roles and Therapeutic Approaches. Am J Respir Cell Mol Biol (2016) 0.75
The Accelerated Child Survival and Development programme in west Africa: a retrospective evaluation. Lancet (2010) 6.56
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging (2010) 5.49
Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease. Ann Neurol (2011) 4.38
Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism. Lancet Neurol (2008) 3.67
Relationship between atrophy and beta-amyloid deposition in Alzheimer disease. Ann Neurol (2010) 3.46
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis. Nat Cell Biol (2006) 3.12
WHO and UNICEF estimates of national infant immunization coverage: methods and processes. Bull World Health Organ (2009) 3.10
Street lighting disturbs commuting bats. Curr Biol (2009) 2.95
Levels and trends in under-5 mortality, 1990-2008. Lancet (2009) 2.86
Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial. Lancet (2011) 2.50
Levels and trends in child mortality, 1990-2009. Lancet (2010) 1.92
Taxon-specific PCR for DNA barcoding arthropod prey in bat faeces. Mol Ecol Resour (2010) 1.84
Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. Am J Respir Cell Mol Biol (2004) 1.83
Fellatio by fruit bats prolongs copulation time. PLoS One (2009) 1.77
An aerial-hawking bat uses stealth echolocation to counter moth hearing. Curr Biol (2010) 1.60
Visual assessment versus quantitative assessment of 11C-PIB PET and 18F-FDG PET for detection of Alzheimer's disease. J Nucl Med (2007) 1.60
Regional dynamics of amyloid-β deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: a voxelwise PiB-PET longitudinal study. Brain (2012) 1.58
A segment of gamma ENaC mediates elastase activation of Na+ transport. J Gen Physiol (2007) 1.57
Inhibition of chloride secretion in human bronchial epithelial cells by cigarette smoke extract. Am J Physiol Lung Cell Mol Physiol (2004) 1.56
Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias. J Nucl Med (2011) 1.54
Sensory neuropathy in human immunodeficiency virus/acquired immunodeficiency syndrome patients: protease inhibitor-mediated neurotoxicity. Ann Neurol (2006) 1.49
High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types. Arch Neurol (2009) 1.45
The hearing gene Prestin reunites echolocating bats. Proc Natl Acad Sci U S A (2008) 1.44
Testing times: do new prenatal tests signal the end of Down syndrome? N Z Med J (2013) 1.42
Molecular diet analysis of two african free-tailed bats (molossidae) using high throughput sequencing. PLoS One (2011) 1.41
Echolocation call intensity in the aerial hawking bat Eptesicus bottae (Vespertilionidae) studied using stereo videogrammetry. J Exp Biol (2005) 1.40
Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease. Brain (2011) 1.39
Phylogeography of the greater horseshoe bat, Rhinolophus ferrumequinum: contrasting results from mitochondrial and microsatellite data. Mol Ecol (2009) 1.36
Aeroecology: probing and modeling the aerosphere. Integr Comp Biol (2008) 1.34
Accelerated FoxP2 evolution in echolocating bats. PLoS One (2007) 1.34
Dynamic evolution of bitter taste receptor genes in vertebrates. BMC Evol Biol (2009) 1.32
Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol (2002) 1.31
Biochemical characterization of prostasin, a channel activating protease. Biochem Biophys Res Commun (2004) 1.30
Evolutionary relationships between bat coronaviruses and their hosts. Emerg Infect Dis (2007) 1.29
The importance of invertebrates when considering the impacts of anthropogenic noise. Proc Biol Sci (2013) 1.29
Intensity control during target approach in echolocating bats; stereotypical sensori-motor behaviour in Daubenton's bats, Myotis daubentonii. J Exp Biol (2002) 1.29
Comparison of 11C-PiB and 18F-florbetaben for Aβ imaging in ageing and Alzheimer's disease. Eur J Nucl Med Mol Imaging (2012) 1.25
Comparing modelled to measured mortality reductions: applying the Lives Saved Tool to evaluation data from the Accelerated Child Survival Programme in West Africa. Int J Epidemiol (2010) 1.23
Larger temporal volume in elderly with high versus low beta-amyloid deposition. Brain (2010) 1.22
Appearance modeling of 11C PiB PET images: characterizing amyloid deposition in Alzheimer's disease, mild cognitive impairment and healthy aging. Neuroimage (2008) 1.15
The 18F-FDG PET cingulate island sign and comparison to 123I-beta-CIT SPECT for diagnosis of dementia with Lewy bodies. J Nucl Med (2009) 1.13
Predicting Alzheimer disease with β-amyloid imaging: results from the Australian imaging, biomarkers, and lifestyle study of ageing. Ann Neurol (2013) 1.13
High-throughput sequencing offers insight into mechanisms of resource partitioning in cryptic bat species. Ecol Evol (2011) 1.12
Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect. Am J Physiol Lung Cell Mol Physiol (2004) 1.10
Mitigating the effect of development on bats in England with derogation licensing. Conserv Biol (2013) 1.08
Head-to-head comparison of 11C-PiB and 18F-AZD4694 (NAV4694) for β-amyloid imaging in aging and dementia. J Nucl Med (2013) 1.06
Adaptive evolution of 5'HoxD genes in the origin and diversification of the cetacean flipper. Mol Biol Evol (2008) 1.06
Flight and echolocation behaviour of whiskered bats commuting along a hedgerow: range-dependent sonar signal design, Doppler tolerance and evidence for 'acoustic focussing'. J Exp Biol (2006) 1.05
In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133. J Nucl Med (2010) 1.03
Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense. Mol Ther (2011) 1.03
Annual mortality rates and excess deaths of children under five in Iraq, 1991-98. Popul Stud (Camb) (2003) 1.01
Echolocation and passive listening by foraging mouse-eared bats Myotis myotis and M. blythii. J Exp Biol (2007) 0.98
Progressive pseudogenization: vitamin C synthesis and its loss in bats. Mol Biol Evol (2010) 0.98
Phylogeography and postglacial recolonization of Europe by Rhinolophus hipposideros: evidence from multiple genetic markers. Mol Ecol (2013) 0.97
MR-less high dimensional spatial normalization of 11C PiB PET images on a population of elderly, mild cognitive impaired and Alzheimer disease patients. Med Image Comput Comput Assist Interv (2008) 0.96
A mixture containing galactooligosaccharide, produced by the enzymic activity of Bifidobacterium bifidum, reduces Salmonella enterica serovar Typhimurium infection in mice. J Med Microbiol (2009) 0.94
Purified galactooligosaccharide, derived from a mixture produced by the enzymic activity of Bifidobacterium bifidum, reduces Salmonella enterica serovar Typhimurium adhesion and invasion in vitro and in vivo. J Med Microbiol (2010) 0.93
High throughput phenotypic analysis of Mycobacterium tuberculosis and Mycobacterium bovis strains' metabolism using biolog phenotype microarrays. PLoS One (2013) 0.93
Mate fidelity and intra-lineage polygyny in greater horseshoe bats. Nature (2005) 0.93
Lentivirus infection causes neuroinflammation and neuronal injury in dorsal root ganglia: pathogenic effects of STAT-1 and inducible nitric oxide synthase. J Immunol (2005) 0.93
Rangewide phylogeography in the greater horseshoe bat inferred from microsatellites: implications for population history, taxonomy and conservation. Mol Ecol (2007) 0.91
Warming up for dinner: torpor and arousal in hibernating Natterer's bats (Myotis nattereri) studied by radio telemetry. J Comp Physiol B (2011) 0.90
Investigation of hypoxia and carbonic anhydrase IX expression in a renal cell carcinoma xenograft model with oxygen tension measurements and ¹²⁴I-cG250 PET/CT. Urol Oncol (2009) 0.90
Recent loss of vitamin C biosynthesis ability in bats. PLoS One (2011) 0.89
Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations. Protein Sci (2009) 0.89
Long-term paternity skew and the opportunity for selection in a mammal with reversed sexual size dimorphism. Mol Ecol (2006) 0.89
HIV and other lentiviral infections cause defects in neutrophil chemotaxis, recruitment, and cell structure: immunorestorative effects of granulocyte-macrophage colony-stimulating factor. J Immunol (2006) 0.89
Detection of antibodies to EBLV-2 in Daubenton's bats in the UK. Vet Rec (2004) 0.88
Population genetic structure and demographic history of the endemic Formosan lesser horseshoe bat (Rhinolophus monoceros). Mol Ecol (2006) 0.87
Understanding signal design during the pursuit of aerial insects by echolocating bats: tools and applications. Integr Comp Biol (2008) 0.87
Mucociliary clearance is enhanced in rat models of cigarette smoke and lipopolysaccharide-induced lung disease. Exp Lung Res (2004) 0.87
Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence. Retrovirology (2011) 0.87
Noninvasive detection of endotoxin-induced mucus hypersecretion in rat lung by MRI. Am J Physiol Lung Cell Mol Physiol (2002) 0.87
Determinants of echolocation call frequency variation in the Formosan lesser horseshoe bat (Rhinolophus monoceros). Proc Biol Sci (2009) 0.86
In vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and Alzheimer disease. Arch Neurol (2011) 0.86
The shaping of genetic variation in edge-of-range populations under past and future climate change. Ecol Lett (2013) 0.85
Brevity is not always a virtue in primate communication. Biol Lett (2010) 0.84
Interdroplet bilayer arrays in millifluidic droplet traps from 3D-printed moulds. Lab Chip (2014) 0.84
A response to criticism of our estimates of under-5 mortality in Iraq, 1980-98. Popul Stud (Camb) (2007) 0.84
HIV type 1-specific inter- and intrasubtype cellular immune responses in HIV type 1-infected Ugandans. AIDS Res Hum Retroviruses (2004) 0.84
Postglacial colonization of Europe by the barbastelle bat: agreement between molecular data and past predictive modelling. Mol Ecol (2012) 0.84
Automated (11)C-PiB standardized uptake value ratio. Acad Radiol (2008) 0.83
P2Y2-receptor-mediated activation of a contralateral, lanthanide-sensitive calcium entry pathway in the human airway epithelium. Br J Pharmacol (2004) 0.83
The influence of flight speed on the ranging performance of bats using frequency modulated echolocation pulses. J Acoust Soc Am (2003) 0.82
Reduced sodium transport with nasal administration of the prostasin inhibitor camostat in subjects with cystic fibrosis. Chest (2013) 0.82
CD12: a new high-flux beamline for ultraviolet and vacuum-ultraviolet circular dichroism on the SRS, Daresbury. J Synchrotron Radiat (2004) 0.82
11C-PiB PET ABri imaging in Worster-Drought syndrome (familial British dementia): a case report. J Alzheimers Dis (2010) 0.82
Adaptive evolution of Leptin in heterothermic bats. PLoS One (2011) 0.82
Getting it right for children: a review of UNICEF joint health and nutrition strategy for 2006-15. Lancet (2006) 0.82
Historical introgression and the persistence of ghost alleles in the intermediate horseshoe bat (Rhinolophus affinis). Mol Ecol (2012) 0.82
HIV Patient Characteristics that Affect Adherence to Exercise Programmes: An Observational Study. Open AIDS J (2010) 0.81
The value of intraoperative PTH measurements in patients with mild primary hyperparathyroidism. Langenbecks Arch Surg (2013) 0.80
Sensory ecology of water detection by bats: a field experiment. PLoS One (2012) 0.80
Evaluation of geometrical sensitivity for respiratory motion gating by GATE and NCAT simulation. Conf Proc IEEE Eng Med Biol Soc (2007) 0.80
Hierarchical polygyny in multiparous lesser flat-headed bats. Mol Ecol (2011) 0.80
Simultaneous analysis of antiretroviral drugs abacavir and tenofovir in human hair by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal (2012) 0.80
Isolation and characterization of CXC receptor genes in a range of elasmobranchs. Dev Comp Immunol (2005) 0.79
On-chip cavity-enhanced absorption spectroscopy using a white light-emitting diode and polymer mirrors. Lab Chip (2015) 0.79
Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging. Neurodegener Dis (2012) 0.79
Adaptive evolution of the myo6 gene in old world fruit bats (family: pteropodidae). PLoS One (2013) 0.79