| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity.
|
Chem Biol
|
2005
|
2.11
|
|
2
|
Structure of bacterial tubulin BtubA/B: evidence for horizontal gene transfer.
|
Proc Natl Acad Sci U S A
|
2005
|
1.59
|
|
3
|
Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization, and cytotoxicity.
|
Chem Biol
|
2004
|
1.46
|
|
4
|
Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines.
|
Cancer Res
|
2004
|
1.45
|
|
5
|
The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.
|
Biochemistry
|
2002
|
1.45
|
|
6
|
Assembly of archaeal cell division protein FtsZ and a GTPase-inactive mutant into double-stranded filaments.
|
J Biol Chem
|
2003
|
1.36
|
|
7
|
Novel polyphenol oxidase mined from a metagenome expression library of bovine rumen: biochemical properties, structural analysis, and phylogenetic relationships.
|
J Biol Chem
|
2006
|
1.36
|
|
8
|
The nucleotide switch of tubulin and microtubule assembly: a polymerization-driven structural change.
|
Biochemistry
|
2006
|
1.28
|
|
9
|
Targeting the assembly of bacterial cell division protein FtsZ with small molecules.
|
ACS Chem Biol
|
2011
|
1.23
|
|
10
|
Tubulin homolog TubZ in a phage-encoded partition system.
|
Proc Natl Acad Sci U S A
|
2012
|
1.19
|
|
11
|
Mapping flexibility and the assembly switch of cell division protein FtsZ by computational and mutational approaches.
|
J Biol Chem
|
2010
|
0.92
|
|
12
|
A purple acidophilic di-ferric DNA ligase from Ferroplasma.
|
Proc Natl Acad Sci U S A
|
2008
|
0.85
|
|
13
|
Probing the pore drug binding site of microtubules with fluorescent taxanes: evidence of two binding poses.
|
Chem Biol
|
2010
|
0.85
|
|
14
|
Inter-conversion of catalytic abilities in a bifunctional carboxyl/feruloyl-esterase from earthworm gut metagenome.
|
Microb Biotechnol
|
2009
|
0.85
|
|
15
|
Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins.
|
J Med Chem
|
2012
|
0.85
|
|
16
|
Folding, stability and polymerization properties of FtsZ chimeras with inserted tubulin loops involved in the interaction with the cytosolic chaperonin CCT and in microtubule formation.
|
J Mol Biol
|
2004
|
0.83
|
|
17
|
Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ.
|
ACS Chem Biol
|
2013
|
0.83
|
|
18
|
New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.
|
ACS Chem Biol
|
2013
|
0.82
|
|
19
|
Interactions of bacterial cell division protein FtsZ with C8-substituted guanine nucleotide inhibitors. A combined NMR, biochemical and molecular modeling perspective.
|
J Am Chem Soc
|
2013
|
0.81
|
|
20
|
Self assembly of human septin 2 into amyloid filaments.
|
Biochimie
|
2011
|
0.81
|
|
21
|
Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches.
|
ACS Chem Biol
|
2014
|
0.80
|
|
22
|
Structural stability of the PsbQ protein of higher plant photosystem II.
|
Biochemistry
|
2004
|
0.78
|
|
23
|
Possible binding site for paclitaxel at microtubule pores.
|
FEBS J
|
2009
|
0.78
|
|
24
|
Fluorescent taxoid probes for microtubule research.
|
Methods Cell Biol
|
2010
|
0.76
|
|
25
|
Psychometric properties of the Aggression Questionnaire: A replication in a sample of partner-assaultive men in psychological treatment.
|
Psicothema
|
2017
|
0.75
|
|
26
|
Urea-induced unfolding studies of free- and ligand-bound tetrameric ATP-dependent Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Influence of quaternary structure on protein conformational stability.
|
Int J Biochem Cell Biol
|
2002
|
0.75
|