Published in Curr Opin Investig Drugs on May 01, 2003
Generation and characterization of p38beta (MAPK11) gene-targeted mice. Mol Cell Biol (2005) 2.19
Molecular basis of MAPK-activated protein kinase 2:p38 assembly. Proc Natl Acad Sci U S A (2007) 1.40
Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis. Proc Natl Acad Sci U S A (2006) 1.37
Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo. Arthritis Res Ther (2005) 1.01
Modulation of host cell signaling pathways as a therapeutic approach in periodontal disease. J Appl Oral Sci (2012) 0.93
Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROS. PLoS One (2013) 0.90
Update on Targets of Biologic Therapies for Rheumatoid Arthritis. Curr Rheumatol Rev (2008) 0.89
MAPK usage in periodontal disease progression. J Signal Transduct (2012) 0.88
Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts. J Clin Invest (2004) 0.86
Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice. Arthritis Res Ther (2009) 0.85
Induction of macrophage migration inhibitory factor in ConA-stimulated rheumatoid arthritis synovial fibroblasts through the P38 map kinase-dependent signaling pathway. Korean J Intern Med (2010) 0.80
Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants. Inflamm Res (2012) 0.78
6-Amino-1-benzyl-4-(4-chloro-phen-yl)-3-(4-pyrid-yl)-1,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile. Acta Crystallogr Sect E Struct Rep Online (2008) 0.75
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site. Nat Struct Biol (2002) 3.92
Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors. J Med Chem (2003) 1.00
The natural history of polyethylene oxidation in total disc replacement. Spine (Phila Pa 1976) (2009) 0.95
The non-diaryl heterocycle classes of p38 MAP kinase inhibitors. Curr Top Med Chem (2002) 0.89
Mapping the deletion endpoints in individuals with 22q11.2 deletion syndrome by droplet digital PCR. BMC Med Genet (2014) 0.87
New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site. Bioorg Med Chem Lett (2007) 0.78
Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores. Bioorg Med Chem Lett (2011) 0.78
Substituted phenyl as a steroid A-ring mimetic: providing agonist activity to a class of arylsulfonamide nonsteroidal glucocorticoid ligands. Bioorg Med Chem Lett (2013) 0.75
The medicinal chemistry of agents targeting the nuclear hormone receptor. Curr Top Med Chem (2008) 0.75