Published in Br J Pharmacol on July 01, 2003
Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes. Br J Pharmacol (2004) 1.17
β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway. Am J Pathol (2011) 1.05
Cytokines and neutrophils as important mediators of platelet-activating factor-induced kinin B1 receptor expression. Br J Pharmacol (2005) 0.85
Effects of the compounds resveratrol, rutin, quercetin, and quercetin nanoemulsion on oxaliplatin-induced hepatotoxicity and neurotoxicity in mice. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.81
Ethical guidelines for investigations of experimental pain in conscious animals. Pain (1983) 17.70
Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol Rev (1992) 4.56
The B1 receptors for kinins. Pharmacol Rev (1998) 2.32
Platelet-activating factor: receptors and signal transduction. Biochem J (1993) 2.12
Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice. Prog Lipid Res (2000) 2.03
Kinin receptors in pain and inflammation. Eur J Pharmacol (2001) 1.66
Kinin B1 receptors: a review. Immunopharmacology (1995) 1.43
Effects of a BLT receptor antagonist on local and remote reperfusion injuries after transient ischemia of the superior mesenteric artery in rats. Eur J Pharmacol (2000) 1.32
Kinins in pain and inflammation. Pain (2000) 1.30
The B1-agonist [des-Arg10]-kallidin activates transcription factor NF-kappaB and induces homologous upregulation of the bradykinin B1-receptor in cultured human lung fibroblasts. J Clin Invest (1998) 1.22
Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules. J Exp Med (2000) 1.13
Kinin receptors. Clin Rev Allergy Immunol (1998) 1.10
Kinins and kinin receptors: importance for the activation of leukocytes. J Leukoc Biol (2000) 1.08
Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse. J Immunol (1996) 1.06
Involvement of B1 and B2 receptors in bradykinin-induced rat paw oedema. Br J Pharmacol (1995) 1.05
Role of the mitogen-activated protein kinases in the expression of the kinin B1 receptors induced by tissue injury. J Immunol (1998) 1.05
Intestinal NF-kappaB is activated, mainly as p50 homodimers, by platelet-activating factor. Biochim Biophys Acta (1998) 1.05
Nuclear factor kappaB dependency of platelet-activating factor-induced angiogenesis. Cancer Res (2002) 1.04
In vivo B1 kinin-receptor upregulation. Evidence for involvement of protein kinases and nuclear factor kappaB pathways. Br J Pharmacol (1999) 1.03
Molecular mechanisms for lipopolysaccharide-induced biphasic activation of nuclear factor-kappa B (NF-kappa B). J Biol Chem (2002) 1.03
Lipopolysaccharide activates nuclear factor kappaB in rat intestine: role of endogenous platelet-activating factor and tumour necrosis factor. Br J Pharmacol (2000) 1.00
Upregulation of B1 receptor mediating des-Arg9-BK-induced rat paw oedema by systemic treatment with bacterial endotoxin. Br J Pharmacol (1996) 0.98
Role of the platelet-activating factor (PAF) receptor during pulmonary infection with gram negative bacteria. Br J Pharmacol (2002) 0.97
Pathogenic responses of bradykinin system in chronic inflammatory rheumatoid disease. Exp Toxicol Pathol (1994) 0.94
Modulation of kinin B1 but not B2 receptors-mediated rat paw edema by IL-1beta and TNFalpha. Peptides (1998) 0.90
The effect of the selectin binding polysaccharide fucoidin on eosinophil recruitment in vivo. Br J Pharmacol (1997) 0.90
Agonist-induced sequestration, recycling, and resensitization of platelet-activating factor receptor. Role of cytoplasmic tail phosphorylation in each process. J Biol Chem (1998) 0.88
Platelet-activating factor (PAF): implications for coronary heart and vascular diseases. Prostaglandins Leukot Essent Fatty Acids (1994) 0.88
Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. Evidence for independent regulatory pathways. J Biol Chem (1996) 0.87
Regulation of kinin receptors in airway epithelial cells by inflammatory cytokines and dexamethasone. Eur J Pharmacol (2002) 0.85
Hypoxia/reoxygenation of human endothelium activates PMNs to detach endothelial cells via a PAF mechanism. J Surg Res (1996) 0.84
Desensitization to PAF-induced rat paw oedema by repeated intraplantar injections. Life Sci (1986) 0.84
Changes in paw oedema triggered via bradykinin B(1) and B(2) receptors in streptozotocin-diabetic rats. Eur J Pharmacol (2001) 0.83
Inflammatory pain: kinins and antagonists. Curr Opin Anaesthesiol (2001) 0.83
The role of B1 and B2 kinin receptors in oedema formation after long-term treatment with Mycobacterium bovis bacillus Calmette-Guérin (BCG). Br J Pharmacol (1997) 0.83
Molecular and pharmacological evidence for modulation of kinin B(1) receptor expression by endogenous glucocorticoids hormones in rats. Br J Pharmacol (2001) 0.83
Selective involvement of reactive oxygen intermediates in platelet-activating factor-mediated activation of NF-kappaB. Inflammation (2000) 0.82
The role of migrating leukocytes in IL-1 beta-induced up-regulation of kinin B(1) receptors in rats. Br J Pharmacol (2002) 0.82
Colonic production and expression of IL-4, IL-6, and IL-10 in neonatal suckling rats after LPS challenge. Am J Physiol Gastrointest Liver Physiol (2001) 0.80
Impaired surface expression of PAF receptors on human neutrophils is dependent upon cell activation. Arch Biochem Biophys (1994) 0.80
Nuclear factor-kappaB activation mediates inducible nitric oxide synthase expression in carrageenin-induced rat pleurisy. Naunyn Schmiedebergs Arch Pharmacol (1999) 0.79
Molecular mechanisms of early inflammation. Thromb Haemost (1997) 0.79
Human umbilical vein endothelial cells: specific binding of platelet-activating factor and cytosolic calcium flux. Biochem Pharmacol (1995) 0.78
Analysis of the mechanisms involved in the inflammatory response induced by des-Arg9-bradykinin in the rat pleural cavity. Inflamm Res (2001) 0.76
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature (2009) 8.71
Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure. Hepatology (2012) 3.31
IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4. J Immunol (2008) 2.83
A randomized trial of carvedilol after renin-angiotensin system inhibition in chronic Chagas cardiomyopathy. Am Heart J (2007) 2.01
Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis. Proc Natl Acad Sci U S A (2009) 1.86
NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis Rheum (2012) 1.83
Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis. J Leukoc Biol (2012) 1.79
Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol (2008) 1.64
Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice. J Immunol (2011) 1.63
IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Ann Rheum Dis (2010) 1.62
The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation. Pain (2009) 1.55
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury. Am J Physiol Renal Physiol (2011) 1.54
Mechanisms involved in IL-6-induced muscular mechanical hyperalgesia in mice. Pain (2010) 1.51
An update on the management of Chagas cardiomyopathy. Expert Rev Anti Infect Ther (2007) 1.50
Increased mortality and inflammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury. Am J Pathol (2002) 1.50
Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules. Planta Med (2004) 1.49
Diagnosis and management of Chagas disease and cardiomyopathy. Nat Rev Cardiol (2012) 1.45
Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein. J Neurosci (2007) 1.44
The essential role of the intestinal microbiota in facilitating acute inflammatory responses. J Immunol (2004) 1.43
The required role of endogenously produced lipoxin A4 and annexin-1 for the production of IL-10 and inflammatory hyporesponsiveness in mice. J Immunol (2007) 1.39
CXCR2-specific chemokines mediate leukotriene B4-dependent recruitment of neutrophils to inflamed joints in mice with antigen-induced arthritis. Arthritis Rheum (2008) 1.39
Dual Role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A. Am J Respir Crit Care Med (2011) 1.38
Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw. Brain Res (2002) 1.36
Down-regulation of CXCR2 on neutrophils in severe sepsis is mediated by inducible nitric oxide synthase-derived nitric oxide. Am J Respir Crit Care Med (2006) 1.35
Ticks produce highly selective chemokine binding proteins with antiinflammatory activity. J Exp Med (2008) 1.34
The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice. J Leukoc Biol (2008) 1.34
Clinical management of chronic Chagas cardiomyopathy. Front Biosci (2003) 1.34
Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway. Proc Natl Acad Sci U S A (2010) 1.34
Activation of the PI3K/Akt pathway early during vaccinia and cowpox virus infections is required for both host survival and viral replication. J Virol (2009) 1.30
CCR5 plays a critical role in the development of myocarditis and host protection in mice infected with Trypanosoma cruzi. J Infect Dis (2005) 1.28
Reappraisal of the immunopathogenesis of disseminated leishmaniasis: in situ and systemic immune response. Trans R Soc Trop Med Hyg (2011) 1.27
Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease. Semin Immunopathol (2012) 1.26
The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature. Arthritis Rheum (2008) 1.26
Expression of IFN-gamma, TNF-alpha, IL-10 and TGF-beta in lymph nodes associates with parasite load and clinical form of disease in dogs naturally infected with Leishmania (Leishmania) chagasi. Vet Immunol Immunopathol (2008) 1.24
Role of the chemokine receptor CXCR2 in bleomycin-induced pulmonary inflammation and fibrosis. Am J Respir Cell Mol Biol (2008) 1.23
Anti-inflammatory and analgesic effects of atorvastatin in a rat model of adjuvant-induced arthritis. Eur J Pharmacol (2005) 1.22
Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea. Eur J Pharmacol (2007) 1.21
The clinical immunology of human Chagas disease. Trends Parasitol (2005) 1.19
Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection. FASEB J (2009) 1.19
Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury. Br J Pharmacol (2004) 1.19
Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes. Br J Pharmacol (2004) 1.17
Role of bradykinin B2 and B1 receptors in the local, remote, and systemic inflammatory responses that follow intestinal ischemia and reperfusion injury. J Immunol (2004) 1.17
Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice. Br J Pharmacol (2004) 1.16
Schistosoma mansoni antigens modulate experimental allergic asthma in a murine model: a major role for CD4+ CD25+ Foxp3+ T cells independent of interleukin-10. Infect Immun (2008) 1.16
Dual function of the long pentraxin PTX3 in resistance against pulmonary infection with Klebsiella pneumoniae in transgenic mice. Microbes Infect (2006) 1.15
Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder. Biochem Pharmacol (2006) 1.15
Resolution of inflammation: mechanisms and opportunity for drug development. Pharmacol Ther (2013) 1.15
Elevated concentrations of CCL2 and tumor necrosis factor-alpha in chagasic cardiomyopathy. Clin Infect Dis (2004) 1.14
Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation. Eur J Med Chem (2011) 1.14
Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammation. J Leukoc Biol (2005) 1.14
Molecular cloning and characterization of a highly selective chemokine-binding protein from the tick Rhipicephalus sanguineus. J Biol Chem (2007) 1.14
Trypanocidal and leishmanicidal properties of substitution-containing chalcones. Antimicrob Agents Chemother (2003) 1.13
Trypanosoma cruzi infection of cultured adipocytes results in an inflammatory phenotype. Obesity (Silver Spring) (2008) 1.12
Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment. Br J Pharmacol (2003) 1.10
Increase in kinins on post-exercise hypotension in normotensive and hypertensive volunteers. Biol Chem (2007) 1.10
Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice. Proc Natl Acad Sci U S A (2010) 1.10
Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis. J Immunol (2013) 1.09
Signaling via platelet-activating factor receptors accounts for the impairment of neutrophil migration in polymicrobial sepsis. J Immunol (2006) 1.09
Caffeic acid derivatives: in vitro and in vivo anti-inflammatory properties. Free Radic Res (2004) 1.09
Platelet-activating factor receptor plays a role in lung injury and death caused by Influenza A in mice. PLoS Pathog (2010) 1.09
Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). J Infect Dis (2012) 1.09
Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection. Proc Natl Acad Sci U S A (2009) 1.08
ACE2-angiotensin-(1-7)-Mas axis in renal ischaemia/reperfusion injury in rats. Clin Sci (Lond) (2010) 1.08
Transscleral-RPE permeability of PEDF and ovalbumin proteins: implications for subconjunctival protein delivery. Invest Ophthalmol Vis Sci (2005) 1.07
Type 1 chemokine receptor expression in Chagas' disease correlates with morbidity in cardiac patients. Infect Immun (2005) 1.07
An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo. J Leukoc Biol (2008) 1.07
IFN-γ production depends on IL-12 and IL-18 combined action and mediates host resistance to dengue virus infection in a nitric oxide-dependent manner. PLoS Negl Trop Dis (2011) 1.06
Kinin B1 receptor up-regulation after lipopolysaccharide administration: role of proinflammatory cytokines and neutrophil influx. J Immunol (2004) 1.06
β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway. Am J Pathol (2011) 1.05
Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice. Pain (2011) 1.03
Transient TLR activation restores inflammatory response and ability to control pulmonary bacterial infection in germfree mice. J Immunol (2011) 1.03
Depressive-like behavior induced by tumor necrosis factor-α in mice. Neuropharmacology (2011) 1.03
Relevance of tumour necrosis factor-alpha for the inflammatory and nociceptive responses evoked by carrageenan in the mouse paw. Br J Pharmacol (2006) 1.03
ST2, an IL-1R family member, attenuates inflammation and lethality after intestinal ischemia and reperfusion. J Leukoc Biol (2006) 1.03
Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway. Neurosci Lett (2003) 1.03
NF-kappaB plays a major role during the systemic and local acute inflammatory response following intestinal reperfusion injury. Br J Pharmacol (2005) 1.02
Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate. Eur J Pharmacol (2006) 1.02
The long pentraxin PTX3 is crucial for tissue inflammation after intestinal ischemia and reperfusion in mice. Am J Pathol (2009) 1.01
Pathogenesis of Chagas disease: time to move on. Front Biosci (Elite Ed) (2012) 1.01
Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus. Life Sci (2002) 1.01
The balance between the production of tumor necrosis factor-alpha and interleukin-10 determines tissue injury and lethality during intestinal ischemia and reperfusion. Mem Inst Oswaldo Cruz (2005) 1.00
Treatment of chronically Trypanosoma cruzi-infected mice with a CCR1/CCR5 antagonist (Met-RANTES) results in amelioration of cardiac tissue damage. Microbes Infect (2008) 1.00
Cardioprotective effects of phosphoramidon on myocardial structure and function in murine Chagas' disease. Int J Parasitol (2002) 0.99
Aging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy. Ann N Y Acad Sci (2010) 0.99
Comparative study of Bifidobacterium animalis, Escherichia coli, Lactobacillus casei and Saccharomyces boulardii probiotic properties. Arch Microbiol (2009) 0.99
Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment. Am J Respir Crit Care Med (2010) 0.98
The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1. FEBS Lett (2009) 0.98
Group A Streptococcus secreted esterase hydrolyzes platelet-activating factor to impede neutrophil recruitment and facilitate innate immune evasion. PLoS Pathog (2012) 0.98
Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection. J Infect Dis (2010) 0.98