Published in Microcirculation on June 01, 2003
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest (2007) 9.09
Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest (2007) 7.02
CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis. Cytokine Growth Factor Rev (2009) 1.93
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infect Immun (2006) 1.87
Dendritic cell-mediated T cell polarization. Springer Semin Immunopathol (2004) 1.72
Chemokines: integrators of pain and inflammation. Nat Rev Drug Discov (2005) 1.68
Gene expression profiling of human decidual macrophages: evidence for immunosuppressive phenotype. PLoS One (2008) 1.55
Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFkB and MAPK dependent pathways in rat astrocytes [corrected]. Brain Res (2009) 1.53
Increased expression of CCL2 in insulin-producing cells of transgenic mice promotes mobilization of myeloid cells from the bone marrow, marked insulitis, and diabetes. Diabetes (2008) 1.31
Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15. J Immunol (2008) 1.30
Redox mechanisms in hepatic chronic wound healing and fibrogenesis. Fibrogenesis Tissue Repair (2008) 1.30
IP-10, MCP-1, MCP-2, MCP-3, and IL-1RA hold promise as biomarkers for infection with M. tuberculosis in a whole blood based T-cell assay. BMC Res Notes (2009) 1.29
MCP-1 contributes to arteriovenous fistula failure. J Am Soc Nephrol (2010) 1.23
Differentiation to the CCR2+ inflammatory phenotype in vivo is a constitutive, time-limited property of blood monocytes and is independent of local inflammatory mediators. J Immunol (2005) 1.20
c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. Mol Cell Biol (2008) 1.20
Transactivation of MCP-1/CCL2 by beta-catenin/TCF-4 in human breast cancer cells. Int J Cancer (2006) 1.09
MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult. J Neuroinflammation (2008) 1.07
Discovery of dual inhibitors of the immune cell PI3Ks p110delta and p110gamma: a prototype for new anti-inflammatory drugs. Chem Biol (2010) 1.05
Monocyte chemotactic protein-1 (MCP-1/CCL2) is associated with prostatic growth dysregulation and benign prostatic hyperplasia. Prostate (2010) 1.03
Paraoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease. BMC Gastroenterol (2009) 0.99
IRAK-M removal counteracts dendritic cell vaccine deficits in migration and longevity. J Immunol (2010) 0.97
Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Hum Reprod (2014) 0.97
Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization. J Biol Chem (2011) 0.96
A randomized, double-blinded, placebo-controlled pilot study of probiotics in active rheumatoid arthritis. Med Sci Monit (2011) 0.95
Leishmania-derived murine monocyte chemoattractant protein 1 enhances the recruitment of a restrictive population of CC chemokine receptor 2-positive macrophages. Infect Immun (2006) 0.93
Differential induction of BLT receptor expression on human endothelial cells by lipopolysaccharide, cytokines, and leukotriene B4. Proc Natl Acad Sci U S A (2006) 0.92
Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs. Front Immunol (2015) 0.90
The ECM proteoglycan decorin links desmoplasia and inflammation in chronic pancreatitis. J Clin Pathol (2006) 0.89
Novel paradigms for dialysis vascular access: downstream vascular biology--is there a final common pathway? Clin J Am Soc Nephrol (2013) 0.89
Spiral ligament fibrocyte-derived MCP-1/CCL2 contributes to inner ear inflammation secondary to nontypeable H. influenzae-induced otitis media. BMC Infect Dis (2010) 0.88
Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 function. J Med Chem (2011) 0.87
Renaming cytokines: MCP-1, major chemokine in pancreatitis. Gut (2005) 0.86
Antigen-specific gene expression profiles of peripheral blood mononuclear cells do not reflect those of T-lymphocyte subsets. Clin Diagn Lab Immunol (2004) 0.83
Transcriptional modulation of intestinal innate defense/inflammation genes by preterm infant microbiota in a humanized gnotobiotic mouse model. PLoS One (2015) 0.81
CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway. Oncotarget (2016) 0.81
Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines. J Transl Med (2007) 0.81
Antibody-enhanced microdialysis collection of CCL2 from rat brain. J Neurosci Methods (2011) 0.80
Urinary chemokines/cytokines are elevated in patients with urolithiasis. Urol Res (2010) 0.80
Ligand supported homology modeling and docking evaluation of CCR2: docked pose selection by consensus scoring. J Mol Model (2011) 0.80
Identification of cytokines in whole blood for differential diagnosis of tuberculosis versus pneumonia. Clin Vaccine Immunol (2010) 0.80
TRAF1 regulates recruitment of lymphocytes and, to a lesser extent, neutrophils, myeloid dendritic cells and monocytes to the lung airways following lipopolysaccharide inhalation. Immunology (2007) 0.79
Monocyte chemoattractant protein 1 does not contribute to protective immunity against pneumococcal pneumonia. Infect Immun (2006) 0.79
Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice. PLoS One (2013) 0.79
Gender-specific effects of genetic variants within Th1 and Th17 cell-mediated immune response genes on the risk of developing rheumatoid arthritis. PLoS One (2013) 0.78
Quantitative structure activities relationships of some 2-mercaptoimidazoles as CCR2 inhibitors using genetic algorithm-artificial neural networks. Res Pharm Sci (2013) 0.78
Alkylsulfone-containing trisubstituted cyclohexanes as potent and bioavailable chemokine receptor 2 (CCR2) antagonists. Bioorg Med Chem Lett (2014) 0.78
Therapeutic Efficacy of an ω-3-Fatty Acid-Containing 17-β Estradiol Nano-Delivery System against Experimental Atherosclerosis. PLoS One (2016) 0.77
Coordinated post-transcriptional regulation of the chemokine system: messages from CCL2. J Interferon Cytokine Res (2014) 0.77
Constitutive and LPS-induced expression of MCP-1 and IL-8 by human uveal melanocytes in vitro and relevant signal pathways. Invest Ophthalmol Vis Sci (2014) 0.76
Chemokine and Chemokine Receptor Polymorphisms in Bipolar Disorder. Psychiatry Investig (2016) 0.76
Future imaging of atherosclerosis: molecular imaging of coronary atherosclerosis with (18)F positron emission tomography. Cardiovasc Diagn Ther (2016) 0.76
Deep sequencing of the uterine immune response to bacteria during the equine oestrous cycle. BMC Genomics (2015) 0.76
Microcystin-Leucine Arginine Causes Cytotoxic Effects in Sertoli Cells Resulting in Reproductive Dysfunction in Male Mice. Sci Rep (2016) 0.76
Future research directions to improve fistula maturation and reduce access failure. Semin Vasc Surg (2016) 0.76
Murine immune response induced by Leishmania major during the implantation of paraffin tablets. Virchows Arch (2010) 0.75
Burkholderia pseudomallei Capsule Exacerbates Respiratory Melioidosis but Does Not Afford Protection against Antimicrobial Signaling or Bacterial Killing in Human Olfactory Ensheathing Cells. Infect Immun (2016) 0.75
A randomized controlled trial on the effects of goal-directed therapy on the inflammatory response open abdominal aortic aneurysm repair. Crit Care (2015) 0.75
Early activated hepatic stellate cell-derived molecules reverse acute hepatic injury. World J Gastroenterol (2015) 0.75
Transcriptome Profiling Reveals Disruption of Innate Immunity in Chronic Heavy Ethanol Consuming Female Rhesus Macaques. PLoS One (2016) 0.75
Role of FXR in Liver Inflammation during Nonalcoholic Steatohepatitis. Curr Pharmacol Rep (2017) 0.75
Polymorphisms of the MCP-1 and HSP70-2 genes in Korean patients with alcoholic chronic pancreatitis. Dig Dis Sci (2008) 0.75
An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice. Nat Med (2003) 6.61
Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood (2010) 4.96
CCL2/Monocyte Chemoattractant Protein-1 regulates inflammatory responses critical to healing myocardial infarcts. Circ Res (2005) 4.14
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood (2009) 3.37
Physicians' attitudes about multiplex tumor genomic testing. J Clin Oncol (2014) 2.62
Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue. Diabetes (2007) 2.54
MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. Blood (2009) 2.28
Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation (2007) 2.14
CCL2 (monocyte chemoattractant protein-1) and cancer. Semin Cancer Biol (2004) 2.11
microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia. Blood (2008) 2.10
The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation. Am J Pathol (2004) 1.88
Cyclin C/cdk3 promotes Rb-dependent G0 exit. Cell (2004) 1.81
DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras. Oncogene (2003) 1.39
RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma. Blood (2009) 1.39
Pathogenesis of Langerhans cell histiocytosis. Annu Rev Pathol (2012) 1.31
Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2. Blood (2005) 1.24
Recent advances in the understanding of Langerhans cell histiocytosis. Br J Haematol (2011) 1.17
Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism. J Immunol (2003) 1.15
The chemokine decoy receptor M3 blocks CC chemokine ligand 2 and CXC chemokine ligand 13 function in vivo. J Immunol (2006) 1.10
MAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosis. Genes Chromosomes Cancer (2015) 1.10
Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice. J Neurosci (2002) 1.08
MCP-1 expression in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci (2002) 1.08
MCP-1-dependent signaling in CCR2(-/-) aortic smooth muscle cells. J Leukoc Biol (2004) 1.07
Absence of CC chemokine ligand 2 results in an altered Th1/Th2 cytokine balance and failure to expel Trichuris muris infection. J Immunol (2003) 1.06
Differential roles of CCL2 and CCR2 in host defense to coronavirus infection. Virology (2004) 1.06
CXC chemokine ligand 12 (stromal cell-derived factor 1 alpha) and CXCR4-dependent migration of CTLs toward melanoma cells in organotypic culture. J Immunol (2005) 1.03
Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice. FASEB J (2005) 1.01
Langerhans cell histiocytosis: malignancy or inflammatory disorder doing a great job of imitating one? Dis Model Mech (2009) 0.95
Selective suppression of monocyte chemoattractant protein-1 expression by human papillomavirus E6 and E7 oncoproteins in human cervical epithelial and epidermal cells. Int J Cancer (2003) 0.95
The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo. J Immunol (2010) 0.94
MCP-1 deficiency is associated with reduced intimal hyperplasia after arterial injury. Biochem Biophys Res Commun (2003) 0.93
Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosis. Blood (2003) 0.93
Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2. Respir Res (2004) 0.91
CC chemokine ligand 2 and its receptor regulate mucosal production of IL-12 and TGF-beta in high dose oral tolerance. J Immunol (2003) 0.91
The effect of MCP-1 depletion on chemokine and chemokine-related gene expression: evidence for a complex network in acute inflammation. Cytokine (2005) 0.90
The chemokine CCL2 is required for control of murine gastric Salmonella enterica infection. Infect Immun (2005) 0.90
Impairment in postischemic neovascularization in mice lacking the CXC chemokine receptor 3. Circ Res (2005) 0.86
Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma. PLoS One (2013) 0.82
Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells. Am J Physiol Lung Cell Mol Physiol (2003) 0.81
Chemokine-based pathogenetic mechanisms in cancer. Novartis Found Symp (2004) 0.80
BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate. AJP Rep (2013) 0.77
Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model. J Vasc Res (2008) 0.77
Innocents abroad: regulating where naive T cells go. Nat Immunol (2008) 0.76
Release the hounds! A chemokine elicits monocytes from bone marrow. Nat Immunol (2006) 0.75
Congenital and Acquired Disorders of Macrophages and Histiocytes. Hematol Oncol Clin North Am (2015) 0.75
Dedication. Hematol Oncol Clin North Am (2015) 0.75