Richard Graeff

Author PubWeight™ 18.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of human CD38 extracellular domain. Structure 2005 1.29
2 Retracted Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH. J Biol Chem 2013 1.16
3 Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells. Biochem J 2003 1.06
4 Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis. J Biol Chem 2006 1.03
5 Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38. Chem Biol 2008 0.98
6 Evidence for a causal role of CD38 expression in granulocytic differentiation of human HL-60 cells. J Biol Chem 2002 0.96
7 Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog. J Biol Chem 2007 0.95
8 Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase. J Biol Chem 2009 0.91
9 Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38. J Biol Chem 2006 0.87
10 ADP-ribosyl cyclase; crystal structures reveal a covalent intermediate. Structure 2004 0.86
11 CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template. PLoS One 2013 0.84
12 Roles of cADPR and NAADP in pancreatic cells. Acta Biochim Biophys Sin (Shanghai) 2012 0.81
13 Structural studies of intermediates along the cyclization pathway of Aplysia ADP-ribosyl cyclase. J Mol Biol 2011 0.80
14 Increased CD38 expression in T cells and circulating anti-CD38 IgG autoantibodies differentially correlate with distinct cytokine profiles and disease activity in systemic lupus erythematosus patients. Cytokine 2013 0.79
15 Dynamic conformations of the CD38-mediated NAD cyclization captured in a single crystal. J Mol Biol 2010 0.79
16 Hierarchical and helical self-assembly of ADP-ribosyl cyclase into large-scale protein microtubes. J Phys Chem B 2008 0.78
17 Comment on "The Arabidopsis circadian clock incorporates a cADPR-based feedback loop". Science 2009 0.77
18 Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium (dagger) (double dagger). Biochemistry 2008 0.77
19 'Click cyclic ADP-ribose': a neutral second messenger mimic. Chem Commun (Camb) 2014 0.77
20 Identification of ADP-ribosylation sites of CD38 mutants by precursor ion scanning mass spectrometry. Anal Biochem 2012 0.76
21 Cyclic adenosine 5'-diphosphate ribose analogs without a "southern" ribose inhibit ADP-ribosyl cyclase-hydrolase CD38. J Med Chem 2014 0.75
22 Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium. Biochemistry 2008 0.75
23 Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH. J Biol Chem 2017 0.75