PubRank

Ajay N Jain

Author PubWeight™ 46.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst 2003 3.65
2 Breast tumor copy number aberration phenotypes and genomic instability. BMC Cancer 2006 3.34
3 Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors. Cancer Res 2003 2.34
4 High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridization. Carcinogenesis 2004 2.13
5 Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway. Cancer Res 2002 1.96
6 Molecular shape and medicinal chemistry: a perspective. J Med Chem 2010 1.91
7 Array-based comparative genomic hybridization for the differential diagnosis of renal cell cancer. Cancer Res 2002 1.84
8 Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. Hum Mol Genet 2004 1.80
9 Parameter estimation for scoring protein-ligand interactions using negative training data. J Med Chem 2006 1.71
10 Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res 2005 1.71
11 Shaping of tumor and drug-resistant genomes by instability and selection. Oncogene 2003 1.70
12 High-resolution analysis of paraffin-embedded and formalin-fixed prostate tumors using comparative genomic hybridization to genomic microarrays. Am J Pathol 2003 1.57
13 Genome-wide-array-based comparative genomic hybridization reveals genetic homogeneity and frequent copy number increases encompassing CCNE1 in fallopian tube carcinoma. Oncogene 2003 1.52
14 Surflex-Dock: Docking benchmarks and real-world application. J Comput Aided Mol Des 2012 1.27
15 Robust ligand-based modeling of the biological targets of known drugs. J Med Chem 2006 1.26
16 Expression of the tumor suppressor gene ARHI in epithelial ovarian cancer is associated with increased expression of p21WAF1/CIP1 and prolonged progression-free survival. Clin Cancer Res 2004 1.22
17 Pathway recognition and augmentation by computational analysis of microarray expression data. Bioinformatics 2005 1.12
18 Customizing scoring functions for docking. J Comput Aided Mol Des 2008 1.11
19 Deriving quantitative conclusions from microarray expression data. Bioinformatics 2002 1.09
20 Chemical structural novelty: on-targets and off-targets. J Med Chem 2011 1.01
21 Effects of inductive bias on computational evaluations of ligand-based modeling and on drug discovery. J Comput Aided Mol Des 2007 1.00
22 Surface-based protein binding pocket similarity. Proteins 2011 0.95
23 Fractional genomic alteration detected by array-based comparative genomic hybridization independently predicts survival after hepatic resection for metastatic colorectal cancer. Clin Cancer Res 2005 0.94
24 A deterministic motif finding algorithm with application to the human genome. Bioinformatics 2006 0.93
25 Physical binding pocket induction for affinity prediction. J Med Chem 2009 0.92
26 Accurate and interpretable computational modeling of chemical mutagenicity. J Chem Inf Model 2008 0.90
27 Magellan: a web based system for the integrated analysis of heterogeneous biological data and annotations; application to DNA copy number and expression data in ovarian cancer. Cancer Inform 2007 0.87
28 Knowledge-guided docking: accurate prospective prediction of bound configurations of novel ligands using Surflex-Dock. J Comput Aided Mol Des 2015 0.85
29 Iterative refinement of a binding pocket model: active computational steering of lead optimization. J Med Chem 2012 0.85
30 Prediction of off-target drug effects through data fusion. Pac Symp Biocomput 2014 0.81
31 Chemical and protein structural basis for biological crosstalk between PPARα and COX enzymes. J Comput Aided Mol Des 2014 0.79
32 A structure-guided approach for protein pocket modeling and affinity prediction. J Comput Aided Mol Des 2013 0.78
33 Compositional structure of repetitive elements is quantitatively related to co-expression of gene pairs. J Mol Biol 2003 0.77
34 Protein function annotation by local binding site surface similarity. Proteins 2013 0.77