Published in Curr Opin Neurol on June 01, 2003
Role of HLA class II genes in susceptibility and resistance to multiple sclerosis: studies using HLA transgenic mice. J Autoimmun (2011) 0.96
Type 1 diabetes mellitus and multiple sclerosis: common etiological features. Nat Rev Endocrinol (2009) 0.95
HLA-DQ6 (DQB1*0601)-restricted T cells protect against experimental autoimmune encephalomyelitis in HLA-DR3.DQ6 double-transgenic mice by generating anti-inflammatory IFN-gamma. J Immunol (2008) 0.95
eae36, a locus on mouse chromosome 4, controls susceptibility to experimental allergic encephalomyelitis in older mice and mice immunized in the winter. Genetics (2005) 0.90
HLA-DQ8 (DQB1*0302)-restricted Th17 cells exacerbate experimental autoimmune encephalomyelitis in HLA-DR3-transgenic mice. J Immunol (2009) 0.85
Three allele combinations associated with multiple sclerosis. BMC Med Genet (2006) 0.80
Interferons in relapsing remitting multiple sclerosis: a systematic review. Lancet (2003) 4.89
A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Res (2010) 4.77
Sex ratio of multiple sclerosis in Canada: a longitudinal study. Lancet Neurol (2006) 3.74
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability. Brain (2010) 3.48
Timing of birth and risk of multiple sclerosis: population based study. BMJ (2004) 2.56
Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis. Nat Genet (2008) 2.45
High reprint orders in medical journals and pharmaceutical industry funding: case-control study. BMJ (2012) 2.37
Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum Mol Genet (2005) 2.26
Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D. PLoS Genet (2009) 2.23
Longitudinal analyses of the effects of neutralizing antibodies on interferon beta-1b in relapsing-remitting multiple sclerosis. Mult Scler (2004) 2.21
Genetics of multiple sclerosis. Lancet Neurol (2004) 2.12
Rare variants in the CYP27B1 gene are associated with multiple sclerosis. Ann Neurol (2011) 2.07
A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Nat Genet (2005) 2.03
Relapses do not matter in relation to long-term disability: yes. Mult Scler (2011) 2.01
Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility. Proc Natl Acad Sci U S A (2009) 1.69
Environmental factors and their timing in adult-onset multiple sclerosis. Nat Rev Neurol (2010) 1.64
Exome sequencing identifies a novel multiple sclerosis susceptibility variant in the TYK2 gene. Neurology (2012) 1.56
The inheritance of resistance alleles in multiple sclerosis. PLoS Genet (2007) 1.54
Multiple sclerosis and birth order: a longitudinal cohort study. Lancet Neurol (2005) 1.54
Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis. Am J Clin Nutr (2008) 1.49
Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans. Genome Res (2012) 1.45
Month of birth, vitamin D and risk of immune-mediated disease: a case control study. BMC Med (2012) 1.44
Epigenetics: molecular mechanisms and implications for disease. Trends Mol Med (2009) 1.31
Genomewide study of multiple sclerosis. N Engl J Med (2007) 1.28
Clinical prognostic factors in multiple sclerosis: a natural history review. Nat Rev Neurol (2009) 1.27
Multiple sclerosis and the major histocompatibility complex. Curr Opin Neurol (2009) 1.19
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex. Hum Mol Genet (2009) 1.17
Mortality in patients with multiple sclerosis. Neurology (2013) 1.15
HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility. Proc Natl Acad Sci U S A (2008) 1.11
Relationship between early clinical characteristics and long term disability outcomes: 16 year cohort study (follow-up) of the pivotal interferon β-1b trial in multiple sclerosis. J Neurol Neurosurg Psychiatry (2011) 1.09
Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium. Hum Mol Genet (2007) 1.08
Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis. J Hum Genet (2009) 1.08
Genetic epidemiology: the use of old and new tools for multiple sclerosis. Trends Neurosci (2008) 1.07
Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences. BMC Med (2012) 1.04
A genome-wide scan in forty large pedigrees with multiple sclerosis. J Hum Genet (2007) 1.02
Association of infectious mononucleosis with multiple sclerosis. A population-based study. Neuroepidemiology (2009) 1.02
Maternal transmission of multiple sclerosis in a dutch population. Arch Neurol (2008) 1.01
Cause of death in MS: long-term follow-up of a randomised cohort, 21 years after the start of the pivotal IFNβ-1b study. BMJ Open (2012) 1.00
Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease. BMC Med (2013) 0.97
Significant linkage to migraine with aura on chromosome 11q24. Hum Mol Genet (2003) 0.96
An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group. Hum Mol Genet (2004) 0.96
Type 1 diabetes mellitus and multiple sclerosis: common etiological features. Nat Rev Endocrinol (2009) 0.95
PRKCA and multiple sclerosis: association in two independent populations. PLoS Genet (2006) 0.95
Geography of hospital admissions for multiple sclerosis in England and comparison with the geography of hospital admissions for infectious mononucleosis: a descriptive study. J Neurol Neurosurg Psychiatry (2011) 0.93
The epidemiology of multiple sclerosis in Scotland: inferences from hospital admissions. PLoS One (2011) 0.92
Multiple sclerosis: major histocompatibility complexity and antigen presentation. Genome Med (2009) 0.92
Genes for multiple sclerosis. Lancet (2008) 0.91
Parental transmission of HLA-DRB1*15 in multiple sclerosis. Hum Genet (2007) 0.91
The genetics of clinical outcome in multiple sclerosis. J Neuroimmunol (2008) 0.90
Functional analysis of missense variants in the TRESK (KCNK18) K channel. Sci Rep (2012) 0.90
A role for VAV1 in experimental autoimmune encephalomyelitis and multiple sclerosis. Sci Transl Med (2009) 0.90
An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1 gene. BMC Med Genet (2009) 0.90
Multiple sclerosis, vitamin D, and HLA-DRB1*15. Neurology (2010) 0.88
Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis. Hum Mol Genet (2010) 0.88
Vitamin D receptor binding, chromatin states and association with multiple sclerosis. Hum Mol Genet (2012) 0.88
Association of smoking with risk of multiple sclerosis: a population-based study. J Neurol (2013) 0.87
Epigenetic mechanisms in multiple sclerosis and the major histocompatibility complex (MHC). Discov Med (2011) 0.87
Early relapses, onset of progression, and late outcome in multiple sclerosis. JAMA Neurol (2013) 0.85
Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians. J Neurol Sci (2011) 0.84
Hand preference and performance in 20 pairs of monozygotic twins with discordant handedness. Cortex (2006) 0.84
Seasonal distribution of psychiatric births in England. PLoS One (2012) 0.83
Association between microchimerism and multiple sclerosis in Canadian twins. J Neuroimmunol (2006) 0.83
A genome-wide scan of male sexual orientation. J Hum Genet (2010) 0.82
Vitamin D intake and incidence of multiple sclerosis. Neurology (2004) 0.82
Inactive or moderately active human promoters are enriched for inter-individual epialleles. Genome Biol (2013) 0.82
Age of onset in concordant twins and other relative pairs with multiple sclerosis. Am J Epidemiol (2009) 0.81
Gestational diabetes and multiple sclerosis. Epidemiology (2009) 0.81
Analysis of 45 candidate genes for disease modifying activity in multiple sclerosis. J Neurol (2008) 0.81
An array of sunshine in multiple sclerosis. N Engl J Med (2002) 0.81
Protein-protein interaction analysis highlights additional loci of interest for multiple sclerosis. PLoS One (2012) 0.80
Chromosome 1p36 in migraine with aura: association study of the 5HT(1D) locus. Neuroreport (2012) 0.79
Epistasis: multiple sclerosis and the major histocompatibility complex. Neurology (2009) 0.79
Seasonality of admissions with multiple sclerosis in Scotland. Eur J Neurol (2010) 0.79
TRPV1 gates tissue access and sustains pathogenicity in autoimmune encephalitis. Mol Med (2013) 0.79
Surrogate endpoints for EDSS worsening in multiple sclerosis: a meta-analytic approach: measuring disability in relapsing-remitting MS. Neurology (2011) 0.79
Prevalence of MS in Iranian immigrants to British Columbia, Canada. J Neurol (2009) 0.78
Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis. Eur J Hum Genet (2009) 0.78
Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis. Eur J Hum Genet (2011) 0.78
No effect of birth weight on the risk of multiple sclerosis. A population-based study. Neuroepidemiology (2008) 0.78
DNA methylation in monozygotic quadruplets affected by type 1 diabetes. Diabetologia (2013) 0.78
Lockhart Clarke's contribution to the description of amyotrophic lateral sclerosis. Brain (2010) 0.78
Mutations in the hemochromatosis gene and the clinical outcome of multiple sclerosis. J Neuroimmunol (2008) 0.78
Clustering of autoimmune disease in families at high risk for multiple sclerosis? Lancet Neurol (2007) 0.77
Early life child exposure and the risk of multiple sclerosis: a population based study. J Neurol Sci (2011) 0.77
Role of the HLA system in the association between multiple sclerosis and infectious mononucleosis. Arch Neurol (2011) 0.77
Methylation of class II transactivator gene promoter IV is not associated with susceptibility to multiple sclerosis. BMC Med Genet (2008) 0.77
Childhood cow's milk allergy and the risk of multiple sclerosis: a population based study. J Neurol Sci (2010) 0.77
Effects of infectious mononucleosis and HLA-DRB1*15 in multiple sclerosis. Mult Scler (2010) 0.77
A first stage genome-wide screen for regions shared identical-by-descent in Hutterite families with multiple sclerosis. Am J Med Genet B Neuropsychiatr Genet (2008) 0.77
Microchimerism in autoimmunity and transplantation: potential relevance to multiple sclerosis. J Neuroimmunol (2002) 0.77
Vitamin D-gene interactions in multiple sclerosis. J Neurol Sci (2011) 0.77
No effect of parental age on risk of multiple sclerosis: a population-based study. Neuroepidemiology (2009) 0.76
Heritability of serum vitamin D concentrations: twin studies. Am J Clin Nutr (2011) 0.76
Month of birth and thymic output. JAMA Neurol (2013) 0.76
No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5. J Neuroimmunol (2010) 0.76
Congenital abnormalities and multiple sclerosis. BMC Neurol (2010) 0.76
Parental non-inherited HLA resistance alleles do not confer protection against multiple sclerosis. J Neuroimmunol (2008) 0.76
Vitamin D-dependent rickets, HLA-DRB1, and the risk of multiple sclerosis. Arch Neurol (2010) 0.76
IGHV4-39 deletion polymorphism does not associate with risk or outcome of multiple sclerosis. J Neuroimmunol (2010) 0.76