Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.
|
EMBO J
|
2002
|
7.93
|
2
|
Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor.
|
J Biol Chem
|
2003
|
4.58
|
3
|
Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man.
|
Sci Transl Med
|
2012
|
3.99
|
4
|
A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees.
|
Nat Med
|
2006
|
3.12
|
5
|
The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA.
|
EMBO J
|
2002
|
3.11
|
6
|
Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro.
|
J Biol Chem
|
2003
|
2.82
|
7
|
A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase.
|
Proc Natl Acad Sci U S A
|
2004
|
2.55
|
8
|
Prime-boost vectored malaria vaccines: progress and prospects.
|
Hum Vaccin
|
2010
|
2.12
|
9
|
Prime-boost immunization with adenoviral and modified vaccinia virus Ankara vectors enhances the durability and polyfunctionality of protective malaria CD8+ T-cell responses.
|
Infect Immun
|
2009
|
2.08
|
10
|
Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion.
|
J Mol Biol
|
2003
|
2.03
|
11
|
Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation.
|
Nat Commun
|
2013
|
1.95
|
12
|
Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species.
|
Sci Transl Med
|
2012
|
1.94
|
13
|
Phase Ia clinical evaluation of the Plasmodium falciparum blood-stage antigen MSP1 in ChAd63 and MVA vaccine vectors.
|
Mol Ther
|
2011
|
1.92
|
14
|
Binding of the hepatitis C virus E2 glycoprotein to CD81 is strain specific and is modulated by a complex interplay between hypervariable regions 1 and 2.
|
J Virol
|
2003
|
1.89
|
15
|
Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector.
|
J Infect Dis
|
2012
|
1.85
|
16
|
ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans.
|
Mol Ther
|
2012
|
1.76
|
17
|
A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope.
|
Proc Natl Acad Sci U S A
|
2005
|
1.74
|
18
|
High-avidity monoclonal antibodies against the human scavenger class B type I receptor efficiently block hepatitis C virus infection in the presence of high-density lipoprotein.
|
J Virol
|
2007
|
1.73
|
19
|
Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors.
|
PLoS One
|
2012
|
1.58
|
20
|
Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators.
|
Hum Gene Ther
|
2002
|
1.50
|
21
|
Role of scavenger receptor class B type I in hepatitis C virus entry: kinetics and molecular determinants.
|
J Virol
|
2010
|
1.33
|
22
|
A novel adenovirus type 6 (Ad6)-based hepatitis C virus vector that overcomes preexisting anti-ad5 immunity and induces potent and broad cellular immune responses in rhesus macaques.
|
J Virol
|
2006
|
1.31
|
23
|
Immune responses against a liver-stage malaria antigen induced by simian adenoviral vector AdCh63 and MVA prime-boost immunisation in non-human primates.
|
Vaccine
|
2010
|
1.29
|
24
|
A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo.
|
Hepatology
|
2011
|
1.28
|
25
|
Inhibition of Nipah virus infection in vivo: targeting an early stage of paramyxovirus fusion activation during viral entry.
|
PLoS Pathog
|
2010
|
1.25
|
26
|
Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells.
|
Mol Cancer Ther
|
2008
|
1.21
|
27
|
Dissecting the biological functions of Drosophila histone deacetylases by RNA interference and transcriptional profiling.
|
J Biol Chem
|
2006
|
1.15
|
28
|
Construction of an rtTA2(s)-m2/tts(kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates.
|
Mol Ther
|
2003
|
1.11
|
29
|
Viral entry inhibitors targeted to the membrane site of action.
|
J Virol
|
2010
|
1.10
|
30
|
Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization.
|
J Immunol
|
2013
|
1.10
|
31
|
Identification of tumor-associated antigens by screening phage-displayed human cDNA libraries with sera from tumor patients.
|
Int J Cancer
|
2003
|
1.09
|
32
|
Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults.
|
PLoS One
|
2013
|
1.09
|
33
|
Development of chimpanzee adenoviruses as vaccine vectors: challenges and successes emerging from clinical trials.
|
Expert Rev Vaccines
|
2013
|
1.08
|
34
|
Molecular dissection of the human B-cell response against Toxoplasma gondii infection by lambda display of cDNA libraries.
|
Int J Parasitol
|
2003
|
1.08
|
35
|
Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor.
|
J Virol
|
2005
|
1.07
|
36
|
A novel, inducible, eukaryotic gene expression system based on the quorum-sensing transcription factor TraR.
|
EMBO Rep
|
2003
|
1.06
|
37
|
Modulation of the immune response induced by gene electrotransfer of a hepatitis C virus DNA vaccine in nonhuman primates.
|
J Immunol
|
2006
|
1.05
|
38
|
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling.
|
J Clin Invest
|
2015
|
0.99
|
39
|
Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice.
|
J Hepatol
|
2012
|
0.99
|
40
|
The kinetics of hepatitis C virus-specific CD8 T-cell responses in the blood mirror those in the liver in acute hepatitis C virus infection.
|
J Virol
|
2008
|
0.98
|
41
|
Tagging genes with cassette-exchange sites.
|
Nucleic Acids Res
|
2005
|
0.98
|
42
|
A novel chimpanzee serotype-based adenoviral vector as delivery tool for cancer vaccines.
|
Vaccine
|
2009
|
0.97
|
43
|
A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activity.
|
PLoS One
|
2012
|
0.94
|
44
|
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents.
|
Hepatology
|
2014
|
0.93
|
45
|
Vaccination to conserved influenza antigens in mice using a novel Simian adenovirus vector, PanAd3, derived from the bonobo Pan paniscus.
|
PLoS One
|
2013
|
0.91
|
46
|
Biotin-tagged cDNA expression libraries displayed on lambda phage: a new tool for the selection of natural protein ligands.
|
Nucleic Acids Res
|
2002
|
0.91
|
47
|
3-Amino-2(5H)furanones as inhibitors of subgenomic hepatitis C virus RNA replication.
|
Bioorg Med Chem
|
2008
|
0.91
|
48
|
Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses.
|
J Virol
|
2014
|
0.90
|
49
|
Adenovirus type 4 and 7 vaccination or adenovirus type 4 respiratory infection elicits minimal cross-reactive antibody responses to nonhuman adenovirus vaccine vectors.
|
Clin Vaccine Immunol
|
2014
|
0.88
|
50
|
Searching for DNA-protein interactions by lambda phage display.
|
J Mol Biol
|
2002
|
0.87
|
51
|
A functionally orthogonal estrogen receptor-based transcription switch specifically induced by a nonsteroid synthetic ligand.
|
Chem Biol
|
2005
|
0.86
|
52
|
A structure-guided approach to an orthogonal estrogen-receptor-based gene switch activated by ligands suitable for in vivo studies.
|
J Med Chem
|
2006
|
0.85
|
53
|
T-cell immunity and hepatitis C virus reinfection after cure of chronic hepatitis C with an interferon-free antiviral regimen in a chimpanzee.
|
Hepatology
|
2014
|
0.85
|
54
|
Differential screening of phage-ab libraries by oligonucleotide microarray technology.
|
PLoS One
|
2008
|
0.84
|
55
|
Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus.
|
Biochemistry
|
2002
|
0.79
|
56
|
A loxP-containing pol II promoter for RNA interference is reversibly regulated by Cre recombinase.
|
RNA Biol
|
2005
|
0.78
|
57
|
Application of phage display peptide library to autoimmune diabetes: identification of IA-2/ICA512bdc dominant autoantigenic epitopes.
|
Eur J Immunol
|
2002
|
0.76
|
58
|
Adeno-cosmid cloning vectors for regulated gene expression.
|
J Gene Med
|
2002
|
0.76
|
59
|
Therapeutic Vaccine Against Primate Papillomavirus Infections of the Cervix.
|
J Immunother
|
2017
|
0.75
|