Published in Ann Oncol on December 01, 1992
Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry (1984) 10.83
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Genet (2000) 5.26
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity (2001) 5.14
Purification to homogeneity and properties of two D-alanine carboxypeptidases I From Escherichia coli. J Biol Chem (1976) 4.66
Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination. Nature (1992) 4.43
Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J Cell Biol (2000) 4.34
Human cerebellar activity reflecting an acquired internal model of a new tool. Nature (2000) 4.29
Prevalence of serum and salivary antibodies to HTLV-1 in Sjögren's syndrome. Lancet (1994) 3.83
Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann Rheum Dis (2008) 3.77
Perceptual learning without perception. Nature (2001) 3.48
Peripheral lung cancer: screening and detection with low-dose spiral CT versus radiography. Radiology (1996) 3.22
High-dose intravenous gammaglobulin for Kawasaki disease. Lancet (1984) 3.10
Lansoprazole, a novel benzimidazole proton pump inhibitor, and its related compounds have selective activity against Helicobacter pylori. Antimicrob Agents Chemother (1991) 3.05
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc Natl Acad Sci U S A (1981) 3.04
Three-year follow-up after implantation of metallic coronary-artery stents. N Engl J Med (1996) 2.95
The effect of zinc supplementation on pregnancy outcome. JAMA (1995) 2.87
Genetic susceptibility to post-thymectomy autoimmune diseases in mice. Immunogenetics (1981) 2.80
The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J Biol Chem (1998) 2.71
Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J Neurosci (2001) 2.54
Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro. Microbiol Immunol (2001) 2.52
Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest (1993) 2.52
Colonoscopic diagnosis and management of nonpolypoid early colorectal cancer. World J Surg (2000) 2.51
Primary structure of heat-labile enterotoxin produced by Escherichia coli pathogenic for humans. J Biol Chem (1984) 2.48
The incidence of secondary tumors of the heart and pericardium: a 10-year study. Jpn J Clin Oncol (1988) 2.47
Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals. J Immunol (1999) 2.44
Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res (1998) 2.42
Increased expression of sialyl Lewisx antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study. Cancer Res (1993) 2.39
Ampulla cardiomyopathy ('Takotusbo' cardiomyopathy)--reversible left ventricular dysfunction: with ST segment elevation. Jpn Circ J (2000) 2.39
Systematic review and meta-analysis of randomised, phase II/III trials adding bevacizumab to platinum-based chemotherapy as first-line treatment in patients with advanced non-small-cell lung cancer. Ann Oncol (2012) 2.38
Two species of human CRK cDNA encode proteins with distinct biological activities. Mol Cell Biol (1992) 2.30
Vitamin A deficiency in mice causes a systemic expansion of myeloid cells. Blood (2000) 2.30
Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J Neurosurg (1990) 2.28
Folic acid safety and toxicity: a brief review. Am J Clin Nutr (1989) 2.17
In vitro peptidoglycan polymerization catalysed by penicillin binding protein 1b of Escherichia coli K-12. FEBS Lett (1980) 2.14
Quality of life and disease-related symptoms in previously treated Japanese patients with non-small-cell lung cancer: results of a randomized phase III study (V-15-32) of gefitinib versus docetaxel. Ann Oncol (2009) 2.14
Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines. Biochem Biophys Res Commun (2000) 2.14
Endotoxin-induced serum factor that stimulates gamma interferon production. Infect Immun (1989) 2.13
Reduced myocardial flow reserve in non-insulin-dependent diabetes mellitus. J Am Coll Cardiol (1997) 2.11
Identification of a new variable sequence in the P1 cytadhesin gene of Mycoplasma pneumoniae: evidence for the generation of antigenic variation by DNA recombination between repetitive sequences. Infect Immun (1999) 2.11
Double-blind randomized control trial of the effect of recombinant human erythropoietin on chemotherapy-induced anemia in patients with non-small cell lung cancer. Int J Clin Oncol (2001) 2.10
Fukuyama-type congenital muscular dystrophy and the Walker-Warburg syndrome. Brain Dev (1993) 2.08
Reaction of sevoflurane and its degradation products with soda lime. Toxicity of the byproducts. Anesthesiology (1992) 2.07
Interferon-gamma induces different subunit organizations and functional diversity of proteasomes. J Biochem (1994) 2.06
Role of the gag and pol genes of human immunodeficiency virus in the morphogenesis and maturation of retrovirus-like particles expressed by recombinant vaccinia virus: an ultrastructural study. J Gen Virol (1991) 2.05
Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth. J Biol Chem (1997) 2.03
Epidemiological study of Mycoplasma pneumoniae infections in japan based on PCR-restriction fragment length polymorphism of the P1 cytadhesin gene. J Clin Microbiol (1996) 2.02
Spontaneous development of autoimmune thyroiditis in neonatally thymectomized mice. Lab Invest (1976) 2.00
Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis. Proc Natl Acad Sci U S A (2000) 1.99
Autoimmune oophoritis in thymectomized mice: detection of circulating antibodies against oocytes. Clin Exp Immunol (1980) 1.98
Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma. Hepatology (1998) 1.97
Dilution is effective in reducing infusion phlebitis in peripheral parenteral nutrition: an experimental study in rabbits. Nutrition (1998) 1.96
Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse. Nat Neurosci (2001) 1.96
Photoplethysmography. Part 1. Comparison with laser Doppler flowmetry. Med Biol Eng Comput (1991) 1.92
Antibodies against synthetic peptides as a tool for functional analysis of the transforming protein pp60src. Cell (1983) 1.91
Endoscopic neck surgery by the axillary approach. J Am Coll Surg (2000) 1.90
Phytochrome-mediated regulation of two mRNAs, encoded by nuclei and chloroplasts of ribulose-1,5-bisphosphate carboxylase/oxygenase. Eur J Biochem (1983) 1.88
Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells. J Antibiot (Tokyo) (1991) 1.86
Transition of brain activation from frontal to parietal areas in visuomotor sequence learning. J Neurosci (1998) 1.85
Changes in distribution of hepatic blood flow induced by intra-arterial infusion of angiotensin II in human hepatic cancer. Cancer (1985) 1.84
Acetyl-CoA carboxylase in higher plants: most plants other than gramineae have both the prokaryotic and the eukaryotic forms of this enzyme. Plant Cell Physiol (1996) 1.83
Enhanced myosin light chain phosphorylations as a central mechanism for coronary artery spasm in a swine model with interleukin-1beta. Circulation (1997) 1.83
Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. Oncogene (2007) 1.81
Effect of captopril on heavy proteinuria in azotemic diabetics. N Engl J Med (1985) 1.81
Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes. Eur J Immunol (1997) 1.81
Compartmentalization of two forms of acetyl-CoA carboxylase in plants and the origin of their tolerance toward herbicides. Proc Natl Acad Sci U S A (1994) 1.80
Association between gain-of-function mutations in PIK3CA and resistance to HER2-targeted agents in HER2-amplified breast cancer cell lines. Ann Oncol (2009) 1.76
Regulation of matrix metalloproteinases (MMP-2, -3, -9, and -13) by interleukin-1 and interleukin-6 in mouse calvaria: association of MMP induction with bone resorption. Endocrinology (1998) 1.75
Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib ('Iressa', ZD1839) in Japanese patients with solid malignant tumors. Ann Oncol (2003) 1.75
Practical usefulness of lymphatic and connective tissue clearance for the carcinoma of the pancreas head. Ann Surg (1988) 1.74
Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma. Cancer Res (1996) 1.74
Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia. J Cell Sci (2000) 1.74
Solid and papillary neoplasm arising from an ectopic pancreas in the mesocolon. Am J Gastroenterol (1990) 1.74
Characterization of adipose tissue-derived cells isolated with the Celution system. Cytotherapy (2008) 1.73
On the process of cellular division in Escherichia coli: isolation and characterization of penicillin-binding proteins 1a, 1b, and 3. Proc Natl Acad Sci U S A (1980) 1.73
Light adaptation in retinal rods of the rabbit and two other nonprimate mammals. J Gen Physiol (1991) 1.73
Tumor necrosis factor-alpha and interleukin-1beta increase the Fas-mediated apoptosis of human osteoblasts. J Lab Clin Med (1999) 1.73
Self-compartmentalizing proteases. Trends Biochem Sci (1997) 1.71
Preparation and characterization of a mouse osteoclast-like multinucleated cell population. J Bone Miner Res (1992) 1.71
Randomized trial of cyclophosphamide, doxorubicin, and vincristine versus cisplatin and etoposide versus alternation of these regimens in small-cell lung cancer. J Natl Cancer Inst (1991) 1.70
Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: possible pathophysiological significance of VEGF in progression of atherosclerosis. Circulation (1998) 1.69
A monoclonal antibody against Igh6-4 determinant. Immunogenetics (1986) 1.68
Seronegative Lambert-Eaton myasthenic syndrome: study of 110 Japanese patients. Neurology (2002) 1.67
Post-translational glycosylation of coronavirus glycoprotein E1: inhibition by monensin. EMBO J (1982) 1.67
Patchy atrophy and lacquer cracks predispose to the development of choroidal neovascularisation in pathological myopia. Br J Ophthalmol (2003) 1.66
Clinical investigation of atypical adenomatous hyperplasia of the lung. Lung Cancer (1999) 1.63
Experimental production of possible autoimmune castritis followed by macrocytic anemia in athymic nude mice. Lab Invest (1980) 1.62
Task-dependent influences of attention on the activation of human primary visual cortex. Proc Natl Acad Sci U S A (1998) 1.60
Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors. J Exp Med (1995) 1.60
Computer-aided diagnosis for pulmonary nodules based on helical CT images. Comput Med Imaging Graph (1998) 1.60
A novel role for interleukin-18 in human natural killer cell death: high serum levels and low natural killer cell numbers in patients with systemic autoimmune diseases. Arthritis Rheum (2001) 1.57
Comparative study of intraoperative mitomycin C and beta irradiation in pterygium surgery. Br J Ophthalmol (2000) 1.56
Neointimal tissue response at sites of coronary stenting in humans: macroscopic, histological, and immunohistochemical analyses. Circulation (1998) 1.56
Effects of erythorbic acid on vitamin C metabolism in young women. Am J Clin Nutr (1996) 1.55