Genetic influences in gastro-oesophageal reflux disease: a twin study.

PubWeight™: 1.85‹?› | Rank: Top 3%

🔗 View Article (PMC 1773757)

Published in Gut on August 01, 2003

Authors

I Mohammed1, L F Cherkas, S A Riley, T D Spector, N J Trudgill

Author Affiliations

1: Department of Gastroenterology, Sandwell General Hospital, West Bromich, UK.

Articles citing this

Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut (2005) 7.35

Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis. Nat Rev Cancer (2010) 3.27

Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut (2013) 2.96

Gastroenterology services in the UK. The burden of disease, and the organisation and delivery of services for gastrointestinal and liver disorders: a review of the evidence. Gut (2007) 2.28

Abdominal obesity, ethnicity and gastro-oesophageal reflux symptoms. Gut (2006) 2.28

Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia. Gut (2009) 1.59

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52

Comparison of endoscopic and clinical characteristics of patients with familial and sporadic Barrett's esophagus. Dig Dis Sci (2011) 1.43

The prevalence of Barrett's esophagus in the US: estimates from a simulation model confirmed by SEER data. Dis Esophagus (2010) 1.42

Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux. J Natl Cancer Inst (2013) 1.25

Lifestyle factors and risk for symptomatic gastroesophageal reflux in monozygotic twins. Gastroenterology (2006) 1.22

Prevalence of gastroesophageal reflux disease symptoms and uninvestigated dyspepsia in Korea: a population-based study. Dig Dis Sci (2007) 1.20

Body weight, lifestyle, dietary habits and gastroesophageal reflux disease. World J Gastroenterol (2009) 1.18

A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China. BMC Gastroenterol (2010) 1.16

Diet, lifestyle and gender in gastro-esophageal reflux disease. Dig Dis Sci (2007) 1.16

A segregation analysis of Barrett's esophagus and associated adenocarcinomas. Cancer Epidemiol Biomarkers Prev (2010) 1.13

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus. Gastroenterology (2014) 1.08

Association between diabetes mellitus and gastroesophageal reflux disease: A meta-analysis. World J Gastroenterol (2015) 1.01

Chronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus. Hum Mol Genet (2015) 1.01

New strategies in Barrett's esophagus: integrating clonal evolutionary theory with clinical management. Clin Cancer Res (2011) 0.96

Genetic contributions to pain: a review of findings in humans. Oral Dis (2008) 0.96

The impact of obesity on the rise in esophageal adenocarcinoma incidence: estimates from a disease simulation model. Cancer Epidemiol Biomarkers Prev (2011) 0.91

The prevalence of laryngopharyngeal reflux in the English population. Eur Arch Otorhinolaryngol (2012) 0.90

Postmenopausal hormone therapy as a risk factor for gastroesophageal reflux symptoms among female twins. Gastroenterology (2008) 0.88

Development, calibration, and validation of a U.S. white male population-based simulation model of esophageal adenocarcinoma. PLoS One (2010) 0.87

Effects of estrogen with and without progestin and obesity on symptomatic gastroesophageal reflux. Gastroenterology (2008) 0.86

Barrett's oesophagus: an ideal model to study cancer genetics. Hum Genet (2009) 0.84

Gastroesophageal reflux disease symptoms: prevalence, sociodemographics and treatment patterns in the adult Israeli population. World J Gastroenterol (2011) 0.83

Genetic Insights in Barrett's Esophagus and Esophageal Adenocarcinoma. Gastroenterology (2015) 0.81

The Impact of Uncertainty in Barrett's Esophagus Progression Rates on Hypothetical Screening and Treatment Decisions. Med Decis Making (2014) 0.81

Gastroesophageal reflux disease and non-esophageal cancer. World J Gastroenterol (2015) 0.78

Prevalence of symptoms of gastroesopahgeal reflux in a cohort of Saudi Arabians: a study of 1265 subjects. Saudi J Gastroenterol (2014) 0.78

Gastroesophageal Reflux Disease and Helicobacter pylori: What May Be the Relationship? J Neurogastroenterol Motil (2010) 0.77

Prevalence of severe esophagitis in Spain. Results of the PRESS study (Prevalence and Risk factors for Esophagitis in Spain: A cross-sectional study). United European Gastroenterol J (2015) 0.77

Lifestyle characteristics and gastroesophageal reflux disease: a population-based study in Albania. Gastroenterol Res Pract (2013) 0.77

Challenges of correlating pH change with relief of clinical symptoms in gastro esophageal reflux disease: a phase III, randomized study of Zegerid versus Losec. PLoS One (2015) 0.77

Dissecting GI phenotype-genotype relationships in GERD and dyspepsia: an SNP here and an SNP there! Am J Gastroenterol (2009) 0.76

4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease. PLoS One (2011) 0.76

Association between interleukin-1beta-511C/T polymorphism and reflux esophagitis in Japan. J Gastroenterol (2005) 0.76

A population-based study of gastroesophageal reflux disease and sleep problems in elderly twins. PLoS One (2012) 0.76

Genetic susceptibility to Barrett's oesophagus: Lessons from early studies. United European Gastroenterol J (2015) 0.75

An Accurate Cancer Incidence in Barrett's Esophagus: A Best Estimate Using Published Data and Modeling. Gastroenterology (2015) 0.75

Progress report. Gut (2004) 0.75

Screening and Identifying Erosive Esophagitis in Children with Non-cardiac Chest Pain. J Korean Med Sci (2016) 0.75

Epidemiology of upper gastrointestinal symptoms in Brazil (EpiGastro): a population-based study according to sex and age group. World J Gastroenterol (2014) 0.75

Germline APC Mutation and Familial Barrett Esophagus: Causal or Coincidence? Gastroenterol Hepatol (N Y) (2011) 0.75

Zero-Inflated Models for Identifying Relationships Between Body Mass Index and Gastroesophageal Reflux Symptoms: A Nationwide Population-Based Study in China. Dig Dis Sci (2016) 0.75

Articles cited by this

Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med (1999) 17.30

Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology (1997) 8.51

Mechanisms of gastroesophageal reflux in patients with reflux esophagitis. N Engl J Med (1982) 5.07

Are twins and singletons comparable? A study of disease-related and lifestyle characteristics in adult women. Twin Res (2001) 4.50

Genetic influences on osteoarthritis in women: a twin study. BMJ (1996) 3.70

Esophageal peristaltic dysfunction in peptic esophagitis. Gastroenterology (1986) 3.16

Risk factors associated with symptoms of gastroesophageal reflux. Am J Med (1999) 2.75

Determinants of gastroesophageal junction incompetence: hiatal hernia, lower esophageal sphincter, or both? Ann Intern Med (1992) 2.06

Prevalence of symptoms suggestive of gastro-oesophageal reflux disease in an adult population. Ann Med (1995) 1.97

Epidemiological differences between adenocarcinoma of the oesophagus and adenocarcinoma of the gastric cardia in the USA. Gut (2002) 1.84

Familial clustering of reflux symptoms. Am J Gastroenterol (1999) 1.84

Transient lower esophageal sphincter relaxations are no more frequent in patients with gastroesophageal reflux disease than in asymptomatic volunteers. Am J Gastroenterol (2001) 1.79

Gastroesophageal reflux disease in monozygotic and dizygotic twins. Gastroenterology (2002) 1.76

Evaluation of esophageal tests in the diagnosis of reflux esophagitis. Gastroenterology (1976) 1.71

The inheritance of scholastric abilities in a sample of twins. I. Ascertainments of the sample and diagnosis of zygosity. Ann Hum Genet (1975) 1.63

Heartburn and globus in apparently healthy people. Can Med Assoc J (1982) 1.58

Mapping of a gene for severe pediatric gastroesophageal reflux to chromosome 13q14. JAMA (2000) 1.56

Familial aggregation of gastroesophageal reflux in patients with Barrett's esophagus and esophageal adenocarcinoma. Gastroenterology (1997) 1.46

Experimental esophagitis in cats impairs lower esophageal sphincter pressure. Gastroenterology (1975) 1.38

Prevalence, severity and associated features of gastro-oesophageal reflux and dyspepsia: a population-based study. N Z Med J (2000) 1.34

Impairment of esophageal emptying with hiatal hernia. Gastroenterology (1991) 1.34

Heritability of respiratory sinus arrhythmia: dependency on task and respiration rate. Psychophysiology (1997) 1.21

Familial Barrett's esophagus associated with adenocarcinoma. Gastroenterology (1992) 1.17

Familial gastroesophageal reflux and development of Barrett's esophagus. Ann Intern Med (1985) 1.16

Familial Barrett esophagus and adenocarcinoma of the gastroesophageal junction. Cancer Epidemiol Biomarkers Prev (1993) 1.04

Motor function of the proximal stomach and visceral perception in gastro-oesophageal reflux disease. Gut (1998) 1.01

Esophageal shortening induced by short-term intraluminal acid perfusion in opossum: a cause for hiatus hernia? Gastroenterology (1994) 0.96

Logistic regression analysis of twin data: estimation of parameters of the multifactorial liability-threshold model. Behav Genet (1994) 0.94

Gastroesophageal reflux disease: new concepts in pathophysiology. Gastroenterol Clin North Am (1989) 0.91

Familial hiatus hernia and gastro-oesophageal reflux. Eur J Pediatr Surg (1996) 0.80

Articles by these authors

Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med (2000) 11.12

Obesity, cigarette smoking, and telomere length in women. Lancet (2005) 8.59

The genetics of haemostasis: a twin study. Lancet (2001) 8.08

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study. Lancet (2008) 7.05

The effects of social status on biological aging as measured by white-blood-cell telomere length. Aging Cell (2006) 6.80

Are twins and singletons comparable? A study of disease-related and lifestyle characteristics in adult women. Twin Res (2001) 4.50

The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study. J Rheumatol (1993) 3.72

The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting. J Clin Endocrinol Metab (2001) 3.55

Genetic control of the circulating concentration of transforming growth factor type beta1. Hum Mol Genet (1999) 3.08

Genetic influences on F cells and other hematologic variables: a twin heritability study. Blood (2000) 2.95

Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study. Endoscopy (2007) 2.88

The assessment of vertebral deformity: a method for use in population studies and clinical trials. Osteoporos Int (1993) 2.66

Genes and environment in refractive error: the twin eye study. Invest Ophthalmol Vis Sci (2001) 2.51

Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study. Arthritis Rheum (1999) 2.46

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium. Osteoarthritis Cartilage (2010) 2.39

Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins. Arthritis Rheum (1999) 2.29

Genes control the cessation of a woman's reproductive life: a twin study of hysterectomy and age at menopause. J Clin Endocrinol Metab (1998) 2.27

HbA(1c) levels are genetically determined even in type 1 diabetes: evidence from healthy and diabetic twins. Diabetes (2001) 2.18

Genetic and environmental factors in age-related nuclear cataracts in monozygotic and dizygotic twins. N Engl J Med (2000) 2.08

Association of birth weight with osteoporosis and osteoarthritis in adult twins. Rheumatology (Oxford) (2003) 2.04

The heritability of bone mineral density, ultrasound of the calcaneus and hip axis length: a study of postmenopausal twins. J Bone Miner Res (1996) 1.99

Association between metabolic factors and knee osteoarthritis in women: the Chingford Study. J Rheumatol (1995) 1.94

Genetic contribution to bone metabolism, calcium excretion, and vitamin D and parathyroid hormone regulation. J Bone Miner Res (2001) 1.93

Genetic influences on muscle strength, lean body mass, and bone mineral density: a twin study. J Bone Miner Res (1997) 1.91

What should we hope to achieve when treating rheumatoid arthritis? Ann Rheum Dis (1989) 1.89

Radiographic assessment of osteoarthritis in population studies: whither Kellgren and Lawrence? Osteoarthritis Cartilage (1993) 1.88

The heritability of age-related cortical cataract: the twin eye study. Invest Ophthalmol Vis Sci (2001) 1.88

Intestinal metaplasia at the squamocolumnar junction in patients attending for diagnostic gastroscopy. Gut (1997) 1.88

Familial clustering of reflux symptoms. Am J Gastroenterol (1999) 1.84

Oral statins and increased bone-mineral density in postmenopausal women. Lancet (2000) 1.83

The association of obesity with osteoarthritis of the hand and knee in women: a twin study. J Rheumatol (1996) 1.82

The relationship between osteoarthritis and osteoporosis in the general population: the Chingford Study. Ann Rheum Dis (1994) 1.82

Clinical signs of early osteoarthritis: reproducibility and relation to x ray changes in 541 women in the general population. Ann Rheum Dis (1991) 1.79

Transient lower esophageal sphincter relaxations are no more frequent in patients with gastroesophageal reflux disease than in asymptomatic volunteers. Am J Gastroenterol (2001) 1.79

Risk factors for gastro-oesophageal reflux disease symptoms: a community study. Aliment Pharmacol Ther (2005) 1.75

Genetic and environmental influences on total-body and central abdominal fat: the effect of physical activity in female twins. Ann Intern Med (1999) 1.74

Cigarette smoking and risk of osteoarthritis in women in the general population: the Chingford study. Ann Rheum Dis (1993) 1.73

The genetic influence on radiographic osteoarthritis is site specific at the hand, hip and knee. Rheumatology (Oxford) (2009) 1.73

Association of polymorphism at the type I collagen (COL1A1) locus with reduced bone mineral density, increased fracture risk, and increased collagen turnover. Arthritis Rheum (1999) 1.70

Choosing the best method for radiological assessment of patellofemoral osteoarthritis. Ann Rheum Dis (1996) 1.66

Serum adiponectin and bone mineral density in women. J Clin Endocrinol Metab (2007) 1.63

Birthweight, vitamin D receptor genotype and the programming of osteoporosis. Paediatr Perinat Epidemiol (2001) 1.61

Association of pain with radiological changes in different compartments and views of the knee joint. Osteoarthritis Cartilage (1996) 1.61

Studies of compliance with delayed-release mesalazine therapy in patients with inflammatory bowel disease. Aliment Pharmacol Ther (2003) 1.57

Patterns of joint involvement in osteoarthritis of the hand: the Chingford Study. J Rheumatol (1995) 1.55

Telomere length in leukocytes correlates with bone mineral density and is shorter in women with osteoporosis. Osteoporos Int (2007) 1.55

Effect of spinal osteophytosis on bone mineral density measurements in vertebral osteoporosis. BMJ (1993) 1.54

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Ann Rheum Dis (2010) 1.53

A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length. J Med Genet (2009) 1.51

Comparison of genome screens for two independent cohorts provides replication of suggestive linkage of bone mineral density to 3p21 and 1p36. Am J Hum Genet (2002) 1.51

The genetic contribution to radiographic hip osteoarthritis in women: results of a classic twin study. Arthritis Rheum (2000) 1.50

Twins. Novel uses to study complex traits and genetic diseases. Trends Genet (2000) 1.47

Comparison of four articular indices for use in clinical trials in rheumatoid arthritis: patient, order and observer variation. J Rheumatol (1991) 1.47

Bone mineral density and vertebral compression fracture rates in ankylosing spondylitis. Ann Rheum Dis (1994) 1.46

Risk factors for progression of lumbar spine disc degeneration: the Chingford Study. Arthritis Rheum (2003) 1.43

A cotwin control study of the relationship between hip osteoarthritis and bone mineral density. Arthritis Rheum (2000) 1.43

The association between osteoarthritis and osteoporotic fracture: the Chingford Study. Br J Rheumatol (1996) 1.42

Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations. Ann Rheum Dis (2008) 1.42

Generalized osteoarthritis in women: pattern of joint involvement and approaches to definition for epidemiological studies. J Rheumatol (1996) 1.40

Effect of sulfasalazine on spermatogenesis. Fertil Steril (1990) 1.40

Effect of hormone replacement therapy on bone mass in rheumatoid arthritis patients treated with and without steroids. Arthritis Rheum (1994) 1.39

Attitudes towards human reproductive cloning, assisted reproduction and gene selection: a survey of 4600 British twins. Hum Reprod (2007) 1.39

Leukocyte telomere length is associated with cognitive performance in healthy women. Neurobiol Aging (2008) 1.36

Genetics of risk factors for melanoma: an adult twin study of nevi and freckles. J Natl Cancer Inst (2000) 1.34

The role of pregnancy in the course and aetiology of rheumatoid arthritis. Clin Rheumatol (1992) 1.33

A mutation in COL9A1 causes multiple epiphyseal dysplasia: further evidence for locus heterogeneity. Am J Hum Genet (2001) 1.33

The classification and assessment of osteoarthritis. Baillieres Clin Rheumatol (1995) 1.32

Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity? Br J Cancer (2007) 1.32

Menopause, oestrogens and arthritis. Maturitas (2000) 1.32

Kellgren & Lawrence grade 1 osteophytes in the knee--doubtful or definite? Osteoarthritis Cartilage (2003) 1.31

The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in women. J Invest Dermatol (2002) 1.29

A comparison of depression rating scales. Br J Psychiatry (1982) 1.21

Radiographic criteria for epidemiologic studies of osteoarthritis. J Rheumatol Suppl (1995) 1.20

Steroid osteoporosis. BMJ (1993) 1.20

Differential methylation of the TRPA1 promoter in pain sensitivity. Nat Commun (2014) 1.19

The effect of rheumatoid arthritis and steroid therapy on bone density in postmenopausal women. Arthritis Rheum (1993) 1.19

Extended haplotypes and linkage disequilibrium in the IL1R1-IL1A-IL1B-IL1RN gene cluster: association with knee osteoarthritis. Genes Immun (2004) 1.18

Immunoglobulin G glycosylation and clinical outcome in rheumatoid arthritis during pregnancy. J Rheumatol (2000) 1.15

Natural history and risk factors for bone loss in postmenopausal Caucasian women: a 15-year follow-up population-based study. Osteoporos Int (2008) 1.14

GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women. Arthritis Rheum (2011) 1.14

Obesity is associated with genetic variants that alter dopamine availability. Ann Hum Genet (2006) 1.13

The big finger: the second to fourth digit ratio is a predictor of sporting ability in women. Br J Sports Med (2006) 1.13

Alveolitis after treatment with amiodarone. Br Med J (Clin Res Ed) (1982) 1.13

Heritability of serum TSH, free T4 and free T3 concentrations: a study of a large UK twin cohort. Clin Endocrinol (Oxf) (2007) 1.12

QT interval in twins. J Hum Hypertens (2000) 1.12

Epidemiology of rheumatoid arthritis: update. Epidemiol Rev (1990) 1.08

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Mol Psychiatry (2011) 1.08

Association between birth weight and adult blood pressure in twins: historical cohort study. BMJ (1999) 1.08

Effect of cigarette smoking on Langerhans' cells. Lancet (1988) 1.08

Evidence of altered bone turnover, vitamin D and calcium regulation with knee osteoarthritis in female twins. Rheumatology (Oxford) (2003) 1.08

Urinary collagen crosslinks reflect the radiographic severity of knee osteoarthritis. Br J Rheumatol (1992) 1.08

The additive effect of individual genes in predicting risk of knee osteoarthritis. Ann Rheum Dis (2007) 1.07

Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts. Osteoarthritis Cartilage (2008) 1.07

Comparison of three methods of intraocular pressure measurement and their relation to central corneal thickness. Eye (Lond) (2010) 1.06

Genetic influence on peripheral blood T lymphocyte levels. Genes Immun (2000) 1.06

Assessment of mechanism of acquired skewed X inactivation by analysis of twins. Blood (2001) 1.06

A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium. J Med Genet (2009) 1.06