Published in Am J Physiol Regul Integr Comp Physiol on July 17, 2003
Motivations and methods for analyzing pulsatile hormone secretion. Endocr Rev (2008) 2.01
Amplification of pulsatile glucagon counterregulation by switch-off of alpha-cell-suppressing signals in streptozotocin-treated rats. Am J Physiol Endocrinol Metab (2008) 0.99
Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp. J Clin Endocrinol Metab (2004) 0.92
System-level control to optimize glucagon counterregulation by switch-off of α-cell suppressing signals in β-cell deficiency. J Diabetes Sci Technol (2009) 0.83
Pancreatic network control of glucagon secretion and counterregulation. Methods Enzymol (2009) 0.82
Irregular and frequent cortisol secretory episodes with preserved diurnal rhythmicity in primary adrenal Cushing's syndrome. J Clin Endocrinol Metab (2004) 0.82
Complementary secretagogue pairs unmask prominent gender-related contrasts in mechanisms of growth hormone pulse renewal in young adults. J Clin Endocrinol Metab (2005) 0.78
Gender modulates sequential suppression and recovery of pulsatile growth hormone secretion by physiological feedback signals in young adults. J Clin Endocrinol Metab (2005) 0.75
Dynamic characteristics of blood glucose time series during the course of critical illness: effects of intensive insulin therapy and relative association with mortality. Crit Care Med (2010) 3.16
Relationship between beta-cell mass and fasting blood glucose concentration in humans. Diabetes Care (2006) 2.46
The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. J Clin Invest (2003) 2.42
Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. Proc Natl Acad Sci U S A (2004) 2.41
Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans. Diabetes (2005) 1.73
Pulsatile insulin secretion: detection, regulation, and role in diabetes. Diabetes (2002) 1.68
Profound amplification of secretory-burst mass and anomalous regularity of ACTH secretory process in patients with Nelson's syndrome compared with Cushing's disease. Clin Endocrinol (Oxf) (2004) 1.62
Cortisol feedback state governs adrenocorticotropin secretory-burst shape, frequency, and mass in a dual-waveform construct: time of day-dependent regulation. Am J Physiol Regul Integr Comp Physiol (2003) 1.61
Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets. Diabetes (2007) 1.57
Interictal and postictal alterations of pulsatile secretions of luteinizing hormone in temporal lobe epilepsy in men. Ann Neurol (2002) 1.54
Sensitivity and specificity of pulse detection using a new deconvolution method. Am J Physiol Endocrinol Metab (2009) 1.49
Physiological control of pituitary hormone secretory-burst mass, frequency, and waveform: a statistical formulation and analysis. Am J Physiol Regul Integr Comp Physiol (2003) 1.45
Acceleration of luteinizing hormone pulse frequency in adolescent girls with a history of central precocious puberty with versus without hyperandrogenism. Horm Res (2007) 1.41
A super-agonist of growth hormone-releasing hormone causes rapid improvement of nutritional status in patients with chronic kidney disease. Kidney Int (2009) 1.40
Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy. Diabetes (2006) 1.40
Composite model of time-varying appearance and disappearance of neurohormone pulse signals in blood. J Theor Biol (2005) 1.33
Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis. Diabetes (2006) 1.16
Reconstruction of in vivo time-evolving neuroendocrine dose-response properties unveils admixed deterministic and stochastic elements. Proc Natl Acad Sci U S A (2004) 1.15
Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein. Am J Physiol Endocrinol Metab (2008) 1.15
Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men. J Clin Endocrinol Metab (2002) 1.13
The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone. Clin Endocrinol (Oxf) (2002) 1.11
Clinical review 171: The rationale, efficacy and safety of androgen therapy in older men: future research and current practice recommendations. J Clin Endocrinol Metab (2004) 1.10
Rapid glucocorticoid receptor-mediated inhibition of hypothalamic-pituitary-adrenal ultradian activity in healthy males. J Neurosci (2010) 1.10
Age attenuates testosterone secretion driven by amplitude-varying pulses of recombinant human luteinizing hormone during acute gonadotrope inhibition in healthy men. J Clin Endocrinol Metab (2007) 1.07
Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes. Diabetes (2011) 1.07
Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women. J Clin Endocrinol Metab (2004) 1.06
Pulsatile insulin secretion by human pancreatic islets. J Clin Endocrinol Metab (2002) 1.04
An ensemble model of the male gonadal axis: illustrative application in aging men. Endocrinology (2006) 1.04
Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats. Am J Physiol Endocrinol Metab (2008) 1.03
Altered growth hormone, cortisol, and leptin secretion in healthy elderly persons with sarcopenia and mixed body composition phenotypes. J Gerontol A Biol Sci Med Sci (2008) 1.03
Deconvolution analysis as a hormone pulse-detection algorithm. Methods Enzymol (2004) 1.02
Dose-response downregulation within the span of single interpulse intervals. Am J Physiol Regul Integr Comp Physiol (2010) 1.02
Endogenous ACTH concentration-dependent drive of pulsatile cortisol secretion in the human. Am J Physiol Endocrinol Metab (2004) 1.02
Sex defines the age dependence of endogenous ACTH-cortisol dose responsiveness. Am J Physiol Regul Integr Comp Physiol (2009) 1.01
Glucose stimulates pulsatile insulin secretion from human pancreatic islets by increasing secretory burst mass: dose-response relationships. J Clin Endocrinol Metab (2003) 1.01
The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women. Aging Cell (2009) 1.00
Estrogen elevates the peak overnight production rate of acylated ghrelin. J Clin Endocrinol Metab (2008) 1.00
Growth hormone release during acute and chronic aerobic and resistance exercise: recent findings. Sports Med (2002) 0.99
Involvement of Sp1 and SREBP-1a in transcriptional activation of the LDL receptor gene by insulin and LH in cultured porcine granulosa-luteal cells. Am J Physiol Endocrinol Metab (2004) 0.98
Intrahepatic transplanted islets in humans secrete insulin in a coordinate pulsatile manner directly into the liver. Diabetes (2006) 0.98
Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men. Am J Physiol Regul Integr Comp Physiol (2003) 0.96
Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets. Endocrinology (2003) 0.96
Cachexia in rheumatoid arthritis is not explained by decreased growth hormone secretion. Arthritis Rheum (2002) 0.95
A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response. Endocrinology (2002) 0.94
Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp. J Clin Endocrinol Metab (2004) 0.94
Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes. Am J Physiol Regul Integr Comp Physiol (2004) 0.94
Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose. J Clin Endocrinol Metab (2004) 0.93
Model-projected mechanistic bases for sex differences in growth hormone regulation in humans. Am J Physiol Regul Integr Comp Physiol (2006) 0.93
Quantifying nonlinear interactions within the hypothalamo-pituitary-adrenal axis in the conscious horse. Endocrinology (2008) 0.93
Putative GH pulse renewal: periventricular somatostatinergic control of an arcuate-nuclear somatostatin and GH-releasing hormone oscillator. Am J Physiol Regul Integr Comp Physiol (2004) 0.92
Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp. J Clin Endocrinol Metab (2004) 0.92
Thigh intermuscular fat is inversely associated with spontaneous GH release in post-menopausal women with abdominal obesity. Eur J Endocrinol (2006) 0.91
Thyrotropin secretion profiles are not different in men and women. J Clin Endocrinol Metab (2009) 0.91
Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade. Am J Physiol Endocrinol Metab (2006) 0.90
Process irregularity of cortisol and adrenocorticotropin secretion in men with major depressive disorder. Psychoneuroendocrinology (2004) 0.90
Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells. Biol Reprod (2002) 0.90
Effects of continuous versus intermittent exercise, obesity, and gender on growth hormone secretion. J Clin Endocrinol Metab (2008) 0.89
Low amplitude and disorderly spontaneous growth hormone release in obese women with or without polycystic ovary syndrome. J Clin Endocrinol Metab (2002) 0.89
Glucose ingestion selectively amplifies ACTH and cortisol secretory-burst mass and enhances their joint synchrony in healthy men. J Clin Endocrinol Metab (2011) 0.88
Somatostatin is essential for the sexual dimorphism of GH secretion, corticosteroid-binding globulin production, and corticosterone levels in mice. Endocrinology (2014) 0.88
A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter function. J Biol Chem (2005) 0.88
Thyrotropin secretion patterns in health and disease. Endocr Rev (2013) 0.88
Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women. J Clin Endocrinol Metab (2008) 0.88
Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal women. J Clin Endocrinol Metab (2007) 0.88
Deterministic construct of amplifying actions of ghrelin on pulsatile growth hormone secretion. Am J Physiol Regul Integr Comp Physiol (2005) 0.87
Prolactin secretion in healthy adults is determined by gender, age and body mass index. PLoS One (2012) 0.87
Control of LH secretory-burst frequency and interpulse-interval regularity in women. Am J Physiol Endocrinol Metab (2003) 0.87
Reduced nocturnal ACTH-driven cortisol secretion during critical illness. Am J Physiol Endocrinol Metab (2014) 0.86
Age-dependent regression analysis of male gonadal axis. Am J Physiol Regul Integr Comp Physiol (2009) 0.86
Growth hormone response to graded exercise intensities is attenuated and the gender difference abolished in older adults. J Appl Physiol (1985) (2005) 0.86
Analytical construct of reversible desensitization of pituitary-testicular signaling: illustrative application in aging. Am J Physiol Regul Integr Comp Physiol (2010) 0.86
Effect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary syndrome. Fertil Steril (2006) 0.86
An early reduction in GH peak amplitude in preproghrelin-deficient male mice has a minor impact on linear growth. Endocrinology (2014) 0.86
Gonadotropin-inhibitory hormone (GnIH) secretion into the ovine hypophyseal portal system. Endocrinology (2012) 0.85
Effects of fasting on physiologically pulsatile insulin release in healthy humans. Diabetes (2002) 0.85
The insulin secretagogues glibenclamide and repaglinide do not influence growth hormone secretion in humans but stimulate glucagon secretion during profound insulin deficiency. J Clin Endocrinol Metab (2004) 0.85
Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism. Clin Endocrinol (Oxf) (2013) 0.85
Pre- versus postmenopausal age, estradiol, and peptide-secretagogue type determine pulsatile growth hormone secretion in healthy women: studies using submaximal agonist drive and an estrogen clamp. J Clin Endocrinol Metab (2009) 0.85
Thyrotropin secretion in mild and severe primary hypothyroidism is distinguished by amplified burst mass and Basal secretion with increased spikiness and approximate entropy. J Clin Endocrinol Metab (2009) 0.84
Graded inhibition of pulsatile luteinizing hormone secretion by a selective gonadotropin-releasing hormone (GnRH)-receptor antagonist in healthy men: evidence that age attenuates hypothalamic GnRH outflow. J Clin Endocrinol Metab (2005) 0.84
Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion. Am J Physiol Endocrinol Metab (2005) 0.84
Increase in daily LH secretion in response to short-term calorie restriction in obese women with PCOS. Am J Physiol Endocrinol Metab (2002) 0.84
Gender governs the relationship between exercise intensity and growth hormone release in young adults. J Appl Physiol (1985) (2002) 0.84
Retention of estradiol negative feedback relationship to LH predicts ovulation in response to caloric restriction and weight loss in obese patients with polycystic ovary syndrome. Am J Physiol Endocrinol Metab (2003) 0.84
Hypocortisolemic clamp unmasks jointly feedforward- and feedback-dependent control of overnight ACTH secretion. Eur J Endocrinol (2008) 0.84
Increasing LH pulsatility in women with hypothalamic amenorrhoea using intravenous infusion of Kisspeptin-54. J Clin Endocrinol Metab (2014) 0.83
Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men. Am J Physiol Endocrinol Metab (2007) 0.83
Diminished and irregular TSH secretion with delayed acrophase in patients with Cushing's syndrome. Eur J Endocrinol (2009) 0.83
Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men. Am J Physiol Regul Integr Comp Physiol (2005) 0.83
Noninvasive analytical estimation of endogenous GnRH drive: analysis using graded competitive GnRH-receptor antagonism and a calibrating pulse of exogenous GnRH. Endocrinology (2011) 0.83
The effects of time following acute growth hormone administration on metabolic and power output measures during acute exercise. J Clin Endocrinol Metab (2004) 0.83
PTH pulsatility but not calcium sensitivity is restored after total parathyroidectomy with heterotopic autotransplantation. J Am Soc Nephrol (2003) 0.83
Octreotide represses secretory-burst mass and nonpulsatile secretion but does not restore event frequency or orderly GH secretion in acromegaly. Am J Physiol Endocrinol Metab (2003) 0.82
Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals. J Clin Endocrinol Metab (2012) 0.82
Age or factors associated with aging attenuate testosterone's concentration-dependent enhancement of the regularity of luteinizing hormone secretion in healthy men. J Clin Endocrinol Metab (2006) 0.82
Do growth hormone (GH) serial sampling, insulin-like growth factor-I (IGF-I) or auxological measurements have an advantage over GH stimulation testing in predicting the linear growth response to GH therapy? Clin Endocrinol (Oxf) (2003) 0.82
Exaggerated 17-hydroxyprogesterone response to intravenous infusions of recombinant human LH in women with polycystic ovary syndrome. Am J Physiol Endocrinol Metab (2004) 0.82
Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsatile ACTH secretion and ACTH approximate entropy in unstressed older men and women. Am J Physiol Regul Integr Comp Physiol (2014) 0.81
Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells. Am J Physiol Endocrinol Metab (2007) 0.81
Aging in healthy men impairs recombinant human luteinizing hormone (LH)-stimulated testosterone secretion monitored under a two-day intravenous pulsatile LH clamp. J Clin Endocrinol Metab (2005) 0.81