Peter J Cullen

Author PubWeight™ 58.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides. Curr Biol 2004 3.76
2 Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1. Nature 2003 3.66
3 SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment. Nat Cell Biol 2007 2.35
4 A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport. Nat Cell Biol 2013 2.18
5 The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. J Cell Sci 2006 2.12
6 The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network. Dev Cell 2009 1.99
7 Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing. Biochem J 2004 1.97
8 A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer. J Cell Sci 2006 1.79
9 The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradation. J Biol Chem 2002 1.73
10 Coincidence detection in phosphoinositide signaling. Trends Cell Biol 2005 1.57
11 SNX-BAR proteins in phosphoinositide-mediated, tubular-based endosomal sorting. Semin Cell Dev Biol 2009 1.49
12 Retromer: a master conductor of endosome sorting. Cold Spring Harb Perspect Biol 2014 1.46
13 Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers. Proc Natl Acad Sci U S A 2007 1.43
14 Recent advances in retromer biology. Traffic 2011 1.43
15 The retromer complex. Adv Enzyme Regul 2009 1.41
16 SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways. J Cell Biol 2012 1.40
17 Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport. J Cell Sci 2005 1.38
18 The retromer component sorting nexin-1 is required for efficient retrograde transport of Shiga toxin from early endosome to the trans Golgi network. J Cell Sci 2007 1.35
19 SNX-BAR-mediated endosome tubulation is co-ordinated with endosome maturation. Traffic 2011 1.27
20 Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules. EMBO J 2012 1.24
21 GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins. J Biol Chem 2006 1.22
22 The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade. Proc Natl Acad Sci U S A 2005 1.13
23 Sorting nexins. Curr Biol 2005 1.12
24 Inositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells. Proc Natl Acad Sci U S A 2007 1.12
25 Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations. EMBO J 2004 1.12
26 Sorting nexin-1 defines an early phase of Salmonella-containing vacuole-remodeling during Salmonella infection. J Cell Sci 2008 1.12
27 CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+. J Cell Biol 2005 1.06
28 Intracellular membrane traffic at high resolution. Methods Cell Biol 2010 1.00
29 The ability of GAP1IP4BP to function as a Rap1 GTPase-activating protein (GAP) requires its Ras GAP-related domain and an arginine finger rather than an asparagine thumb. Mol Cell Biol 2009 0.91
30 Microtubule motors mediate endosomal sorting by maintaining functional domain organization. J Cell Sci 2013 0.90
31 Membrane curvature: the power of bananas, zeppelins and boomerangs. Curr Biol 2007 0.89
32 The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport. Mol Biol Cell 2008 0.89
33 Engineering the phosphoinositide-binding profile of a class I pleckstrin homology domain. J Biol Chem 2003 0.87
34 SNX15 links clathrin endocytosis to the PtdIns3P early endosome independently of the APPL1 endosome. J Cell Sci 2013 0.86
35 Analyzing the role of the putative inositol 1,3,4,5-tetrakisphosphate receptor GAP1IP4BP in intracellular Ca2+ homeostasis. J Biol Chem 2002 0.85
36 Clathrin is not required for SNX-BAR-retromer-mediated carrier formation. J Cell Sci 2012 0.81
37 Control of Ras cycling by Ca2+. FEBS Lett 2003 0.80
38 IP3 3-kinase opposes NGF driven neurite outgrowth. PLoS One 2012 0.79
39 Studying the spatial and temporal regulation of Ras GTPase-activating proteins. Methods Enzymol 2006 0.77
40 Signaling: retromer arrests receptor on the run. Nat Chem Biol 2011 0.75
41 GFP fusion proteins to study signaling in live cells. Methods Mol Biol 2004 0.75