Published in J Neurosci on July 30, 2003
Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron (2006) 6.50
Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system. Annu Rev Neurosci (2008) 5.12
Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell (2008) 3.63
Atorvastatin induction of VEGF and BDNF promotes brain plasticity after stroke in mice. J Cereb Blood Flow Metab (2005) 2.65
New insights in the biology of BDNF synthesis and release: implications in CNS function. J Neurosci (2009) 2.40
Communication between the synapse and the nucleus in neuronal development, plasticity, and disease. Annu Rev Cell Dev Biol (2008) 2.40
Brain-derived neurotrophic factor and the development of structural neuronal connectivity. Dev Neurobiol (2010) 2.04
Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin. Nat Med (2012) 1.90
A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. Hum Mol Genet (2008) 1.87
Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. Neuron (2013) 1.79
SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci (2010) 1.71
Mechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disorders. Annu Rev Neurosci (2010) 1.68
Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia? Biol Psychiatry (2009) 1.59
Cognitive and magnetic resonance imaging brain morphometric correlates of brain-derived neurotrophic factor Val66Met gene polymorphism in patients with schizophrenia and healthy volunteers. Arch Gen Psychiatry (2006) 1.59
Endothelial nitric oxide synthase regulates brain-derived neurotrophic factor expression and neurogenesis after stroke in mice. J Neurosci (2005) 1.54
miR-132 mediates the integration of newborn neurons into the adult dentate gyrus. PLoS One (2011) 1.52
Sprouting, regeneration and circuit formation in the injured spinal cord: factors and activity. Philos Trans R Soc Lond B Biol Sci (2006) 1.48
Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons. Hippocampus (2011) 1.46
Molecular mechanisms of dendrite stability. Nat Rev Neurosci (2013) 1.44
NT-3 replacement with brain-derived neurotrophic factor redirects vestibular nerve fibers to the cochlea. J Neurosci (2004) 1.42
Association between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophrenia. Am J Psychiatry (2007) 1.33
Neurosphere-derived cells exert a neuroprotective action by changing the ischemic microenvironment. PLoS One (2007) 1.33
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. J Clin Invest (2014) 1.23
Postsynaptic TrkB signaling has distinct roles in spine maintenance in adult visual cortex and hippocampus. Proc Natl Acad Sci U S A (2006) 1.20
Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice. Hum Mol Genet (2012) 1.16
Automated Sholl analysis of digitized neuronal morphology at multiple scales: Whole cell Sholl analysis versus Sholl analysis of arbor subregions. Cytometry A (2010) 1.13
Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo. Dev Neurobiol (2009) 1.12
Dynamic plasticity: the role of glucocorticoids, brain-derived neurotrophic factor and other trophic factors. Neuroscience (2012) 1.10
Phosphoinositide 3-kinase enhancer regulates neuronal dendritogenesis and survival in neocortex. J Neurosci (2011) 1.08
Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease. Neuroscience (2008) 1.08
A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor. J Psychiatr Res (2014) 1.08
Neurotrophin/Trk receptor signaling mediates C/EBPalpha, -beta and NeuroD recruitment to immediate-early gene promoters in neuronal cells and requires C/EBPs to induce immediate-early gene transcription. Neural Dev (2007) 1.06
Enhanced neurogenesis and cell migration following focal ischemia and peripheral stimulation in mice. Dev Neurobiol (2008) 1.05
Promoter specific alterations of brain-derived neurotrophic factor mRNA in schizophrenia. Neuroscience (2010) 1.05
Sustained expression of brain-derived neurotrophic factor is required for maintenance of dendritic spines and normal behavior. Neuroscience (2012) 1.04
Disruption of Foxg1 expression by knock-in of cre recombinase: effects on the development of the mouse telencephalon. Neuroscience (2007) 1.03
Epithelial-derived brain-derived neurotrophic factor is required for gustatory neuron targeting during a critical developmental period. J Neurosci (2009) 1.02
Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro. Mol Biol Cell (2008) 1.01
7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss. PLoS One (2014) 1.01
Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development. Proc Natl Acad Sci U S A (2012) 0.99
Molecular and neural bases underlying roles of BDNF in the control of body weight. Front Neurosci (2013) 0.98
Decreased BDNF and TrkB mRNA expression in multiple cortical areas of patients with schizophrenia and mood disorders. Transl Psychiatry (2014) 0.98
Genetic evidence that brain-derived neurotrophic factor mediates competitive interactions between individual cortical neurons. Proc Natl Acad Sci U S A (2012) 0.97
Neurodevelopment, GABA system dysfunction, and schizophrenia. Neuropsychopharmacology (2014) 0.96
Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland. Science (2012) 0.96
Developmental expression of Kcnq4 in vestibular neurons and neurosensory epithelia. Brain Res (2007) 0.95
Roles for gamma-aminobutyric acid in the development of the paraventricular nucleus of the hypothalamus. J Comp Neurol (2010) 0.95
Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation. J Neurosci (2012) 0.94
BDNF is required for the survival of differentiated geniculate ganglion neurons. Dev Biol (2010) 0.94
TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis. Proc Natl Acad Sci U S A (2008) 0.93
The BDNF effects on dendritic spines of mature hippocampal neurons depend on neuronal activity. Front Synaptic Neurosci (2014) 0.93
Integrin α3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior. J Neurosci (2013) 0.93
The cellular and molecular basis of direction selectivity of Aδ-LTMRs. Cell (2014) 0.93
Prelimbic cortex bdnf knock-down reduces instrumental responding in extinction. Learn Mem (2009) 0.91
Both pre- and postsynaptic activity of Nsf prevents degeneration of hair-cell synapses. PLoS One (2011) 0.91
Rit signaling contributes to interferon-gamma-induced dendritic retraction via p38 mitogen-activated protein kinase activation. J Neurochem (2008) 0.91
Structural plasticity of the adult brain: how animal models help us understand brain changes in depression and systemic disorders related to depression. Dialogues Clin Neurosci (2004) 0.90
BDNF signaling and survival of striatal neurons. Front Cell Neurosci (2014) 0.90
Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure. Alcohol Clin Exp Res (2006) 0.90
KIF1A inhibition immortalizes brain stem cells but blocks BDNF-mediated neuronal migration. Nat Neurosci (2016) 0.89
Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation. Front Aging Neurosci (2015) 0.89
Cell adhesion signaling pathways: First responders to cocaine exposure? Commun Integr Biol (2011) 0.89
Therapeutic benefit of treatment of stroke with simvastatin and human umbilical cord blood cells: neurogenesis, synaptic plasticity, and axon growth. Cell Transplant (2012) 0.88
Controlled contusion injury alters molecular systems associated with cognitive performance. J Neurosci Res (2009) 0.88
Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation. Mol Cell Neurosci (2013) 0.86
Location and connectivity determine GABAergic interneuron survival in the brains of South Hampshire sheep with CLN6 neuronal ceroid lipofuscinosis. Neurobiol Dis (2008) 0.86
Activity-dependent regulation of dendritic growth and maintenance by glycogen synthase kinase 3β. Nat Commun (2013) 0.86
Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation. J Biol Chem (2013) 0.86
Epibranchial placode-derived neurons produce BDNF required for early sensory neuron development. Dev Dyn (2011) 0.86
BDNF-TrkB signaling in striatopallidal neurons controls inhibition of locomotor behavior. Nat Commun (2013) 0.85
Discrete BDNF Neurons in the Paraventricular Hypothalamus Control Feeding and Energy Expenditure. Cell Metab (2015) 0.85
Intraarterial transplantation of human umbilical cord blood mononuclear cells is more efficacious and safer compared with umbilical cord mesenchymal stromal cells in a rodent stroke model. Stem Cell Res Ther (2014) 0.85
The effect of BDNF val66met polymorphism on visuomotor adaptation. Exp Brain Res (2012) 0.85
Low-dose candesartan enhances molecular mediators of neuroplasticity and subsequent functional recovery after ischemic stroke in rats. Mol Neurobiol (2014) 0.84
Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration. Exp Neurol (2010) 0.84
The group 2 metabotropic glutamate receptor agonist LY379268 rescues neuronal, neurochemical and motor abnormalities in R6/2 Huntington's disease mice. Neurobiol Dis (2012) 0.83
Postsynaptic localization of PSD-95 is regulated by all three pathways downstream of TrkB signaling. Front Synaptic Neurosci (2014) 0.82
Midbrain-derived neurotrophins support survival of immature striatal projection neurons. J Neurosci (2013) 0.82
Physiological variability in brain-derived neurotrophic factor expression predicts dendritic spine density in the mouse dentate gyrus. Neurosci Lett (2011) 0.82
Brain-derived neurotrophic factor from bone marrow-derived cells promotes post-injury repair of peripheral nerve. PLoS One (2012) 0.82
Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aβ or tau pathology. PLoS One (2012) 0.81
Polymorphism of brain derived neurotrophic factor influences β amyloid load in cognitively intact apolipoprotein E ε4 carriers. Neuroimage Clin (2013) 0.81
Consequences of brain-derived neurotrophic factor withdrawal in CNS neurons and implications in disease. Neurobiol Dis (2016) 0.81
TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease. Proc Natl Acad Sci U S A (2016) 0.81
Influence of chronic moderate sleep restriction and exercise training on anxiety, spatial memory, and associated neurobiological measures in mice. Behav Brain Res (2013) 0.81
Differential loss of thalamostriatal and corticostriatal input to striatal projection neuron types prior to overt motor symptoms in the Q140 knock-in mouse model of Huntington's disease. Front Syst Neurosci (2014) 0.81
BDNF variants, premorbid educational attainment, and disease characteristics in Alzheimer's disease: an exploratory study. J Alzheimers Dis (2009) 0.80
BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice. Brain Res (2012) 0.80
Transforming growth factor alpha attenuates the functional expression of AMPA receptors in cortical GABAergic neurons. Mol Cell Neurosci (2006) 0.80
The protein dendrite arborization and synapse maturation 1 (Dasm-1) is dispensable for dendrite arborization. Mol Cell Biol (2008) 0.80
Glia determine the course of brain-derived neurotrophic factor-mediated dendritogenesis and provide a soluble inhibitory cue to dendritic growth in the brainstem. Neuroscience (2012) 0.80
Blood BDNF level is gender specific in severe depression. PLoS One (2015) 0.79
Neurotrophin ligand-receptor systems in somatosensory cortex of adult rat are affected by repeated episodes of ethanol. Exp Neurol (2007) 0.79
Mechanism of hyperphagia contributing to obesity in brain-derived neurotrophic factor knockout mice. Neuroscience (2012) 0.79
The Therapeutic Potential of Exercise to Improve Mood, Cognition, and Sleep in Parkinson's Disease. Mov Disord (2015) 0.79
BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome. Mol Neurobiol (2015) 0.78
Taste Bud-Derived BDNF Is Required to Maintain Normal Amounts of Innervation to Adult Taste Buds(1,2,3). eNeuro (2015) 0.78
Brain-derived neurotrophic factor is required for axonal growth of selective groups of neurons in the arcuate nucleus. Mol Metab (2015) 0.78
Loss of neurotrophin-3 from smooth muscle disrupts vagal gastrointestinal afferent signaling and satiation. Am J Physiol Regul Integr Comp Physiol (2013) 0.78
An in vitro model of human neocortical development using pluripotent stem cells: cocaine-induced cytoarchitectural alterations. Dis Model Mech (2014) 0.78
Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage. J Neurosci (2002) 5.68
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci (2003) 4.83
Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell (2008) 3.63
FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies. Neuron (2003) 2.86
Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction. Nat Neurosci (2004) 2.41
Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Nature (2005) 2.33
Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor. J Neurosci (2004) 2.16
Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin. Nat Med (2012) 1.90
Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron (2003) 1.73
Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration. J Neurosci (2007) 1.66
Massive loss of Cajal-Retzius cells does not disrupt neocortical layer order. Development (2006) 1.56
Conservation of regional gene expression in mouse and human brain. PLoS Genet (2007) 1.47
Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta. J Neurosci (2005) 1.35
Intracranial plaque enhancement in patients with cerebrovascular events on high-spatial-resolution MR images. Radiology (2014) 1.35
Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. J Neurosci (2002) 1.24
Role for the alpha7beta1 integrin in vascular development and integrity. Dev Dyn (2005) 1.23
Brain-derived neurotrophic factor is present in adult mouse taste cells with synapses. J Comp Neurol (2003) 1.23
Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons. Mol Cell Neurosci (2003) 1.21
Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells. J Cell Biol (2006) 1.04
Genetic evidence that brain-derived neurotrophic factor mediates competitive interactions between individual cortical neurons. Proc Natl Acad Sci U S A (2012) 0.97
Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland. Science (2012) 0.96
Targeted inactivation of cystic fibrosis transmembrane conductance regulator chloride channel gene prevents ischemic preconditioning in isolated mouse heart. Circulation (2004) 0.95
Sall1 regulates cortical neurogenesis and laminar fate specification in mice: implications for neural abnormalities in Townes-Brocks syndrome. Dis Model Mech (2011) 0.95
Stroke and Cancer- A Complicated Relationship. J Neurol Transl Neurosci (2015) 0.93
Conditional activation of Pax6 in the developing cortex of transgenic mice causes progenitor apoptosis. Development (2007) 0.93
Emx1-lineage progenitors differentially contribute to neural diversity in the striatum and amygdala. J Neurosci (2009) 0.90
Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation. Mol Cell Neurosci (2013) 0.86
BDNF promoter-mediated beta-galactosidase expression in the olfactory epithelium and bulb. Chem Senses (2008) 0.85
Sensory-dependent asymmetry for a urine-responsive olfactory bulb glomerulus. J Comp Neurol (2008) 0.84
Differentiation of transverse sinus thrombosis from congenitally atretic cerebral transverse sinus with CT. Stroke (2012) 0.82
Peripheral nerve injury induces immediate increases in layer v neuronal activity. Neurorehabil Neural Repair (2013) 0.82
Neurotrophin-3 is expressed in a discrete subset of olfactory receptor neurons in the mouse. J Comp Neurol (2003) 0.81
Transgene delivery via intracellular electroporetic nanoinjection. Transgenic Res (2013) 0.78
Nanoinjection: pronuclear DNA delivery using a charged lance. Transgenic Res (2012) 0.78
Loss of neurotrophin-3 from smooth muscle disrupts vagal gastrointestinal afferent signaling and satiation. Am J Physiol Regul Integr Comp Physiol (2013) 0.78
Diagnosing CNS vasculitis: the case against empiric treatment. Neurologist (2012) 0.75