A yeast under cover: the capsule of Cryptococcus neoformans.

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Published in Eukaryot Cell on August 01, 2003

Authors

Indrani Bose1, Amy J Reese, Jeramia J Ory, Guilhem Janbon, Tamara L Doering

Author Affiliations

1: Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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Basic local alignment search tool. J Mol Biol (1990) 659.07

G proteins and dual control of adenylate cyclase. Cell (1984) 11.05

A new genus, filobasidiella, the perfect state of Cryptococcus neoformans. Mycologia (1976) 6.24

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes. Annu Rev Biochem (1990) 5.02

Serologic grouping of Cryptococcus neoformans. Proc Soc Exp Biol Med (1968) 4.97

Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. Genes Dev (1997) 4.28

Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulence. Mol Cell Biol (1994) 4.22

The biochemistry and genetics of capsular polysaccharide production in bacteria. Annu Rev Microbiol (1996) 4.13

Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide. J Clin Invest (1985) 3.98

Cryptococcus neoformans. 3. Inhibition of phagocytosis. J Bacteriol (1968) 3.48

Polysaccharide antigens of the capsule of Cryptococcus neoformans. Infect Immun (1994) 3.46

Dimorphism and haploid fruiting in Cryptococcus neoformans: association with the alpha-mating type. Proc Natl Acad Sci U S A (1996) 3.35

Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes. Eukaryot Cell (2002) 3.12

Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans. Mol Cell Biol (2001) 3.11

Capsular polysaccharides of Cryptococcus neoformans. Rev Infect Dis (1984) 3.10

Cryptococcus neoformans. II. Phagocytosis by human leukocytes. J Bacteriol (1967) 3.09

Genetic and phenotypic characterization of capsule mutants of Cryptococcus neoformans. J Bacteriol (1982) 2.96

Distribution and deposition of inhaled particles in respiratory tract. Bacteriol Rev (1961) 2.95

Non-encapsulated variant of Cryptococcus neoformans. II. Surface receptors for cryptococcal polysaccharide and their role in inhibition of phagocytosis by polysaccharide. Infect Immun (1977) 2.84

Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm. Proc Natl Acad Sci U S A (2002) 2.68

The second capsule gene of cryptococcus neoformans, CAP64, is essential for virulence. Infect Immun (1996) 2.67

Karyotyping of Cryptococcus neoformans as an epidemiological tool. J Clin Microbiol (1993) 2.50

The antigenic composition of Cryptococcus neoformans. I. A serologic classification by means of the capsular and agglutination reactions. J Immunol (1950) 2.47

Restriction fragment length polymorphism analysis of Cryptococcus neoformans isolates from environmental (pigeon excreta) and clinical sources in New York City. J Clin Microbiol (1994) 2.43

Serologic evidence for Cryptococcus neoformans infection in early childhood. Pediatrics (2001) 2.40

RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans. Mol Microbiol (2000) 2.30

Molecular organization of the cell wall of Candida albicans. Med Mycol (2001) 2.28

Melanin and virulence in Cryptococcus neoformans. Curr Opin Microbiol (2000) 2.24

Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans. Eukaryot Cell (2002) 2.21

What makes Cryptococcus neoformans a pathogen? Emerg Infect Dis (1998) 2.18

Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans. Infect Immun (1996) 2.15

Microevolution of a standard strain of Cryptococcus neoformans resulting in differences in virulence and other phenotypes. Infect Immun (1998) 2.12

Serological, electrophoretic, and biological properties of Cryptococcus neoformans antigens. Infect Immun (1988) 2.11

Cryptococcus neoformans chemotyping by quantitative analysis of 1H nuclear magnetic resonance spectra of glucuronoxylomannans with a computer-simulated artificial neural network. Clin Diagn Lab Immunol (1998) 2.10

Isolation of the third capsule-associated gene, CAP60, required for virulence in Cryptococcus neoformans. Infect Immun (1998) 2.10

Cell-wall glucans of Cryptococcus neoformans Cap 67. Carbohydr Res (1990) 2.08

Conserved cAMP signaling cascades regulate fungal development and virulence. FEMS Microbiol Rev (2001) 2.04

Regulation of cryptococcal capsular polysaccharide by iron. J Infect Dis (1993) 2.03

Fungal cell wall synthesis: the construction of a biological structure. Microbiol Sci (1988) 2.02

Cell wall architecture in yeast: new structure and new challenges. J Bacteriol (1998) 1.87

How does Cryptococcus get its coat? Trends Microbiol (2000) 1.86

Pathogenesis of pulmonary Cryptococcus neoformans infection in the rat. Infect Immun (1994) 1.83

Functional cloning and characterization of a UDP- glucuronic acid decarboxylase: the pathogenic fungus Cryptococcus neoformans elucidates UDP-xylose synthesis. Proc Natl Acad Sci U S A (2001) 1.80

The Cryptococcus neoformans STE12alpha gene: a putative Saccharomyces cerevisiae STE12 homologue that is mating type specific. Mol Microbiol (1997) 1.79

Isolation, characterization, and localization of a capsule-associated gene, CAP10, of Cryptococcus neoformans. J Bacteriol (1999) 1.79

Capsule synthesis by Cryptococcus neoformans. Trans N Y Acad Sci (1958) 1.76

The STE12alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans. Genetics (1999) 1.75

Cas1p is a membrane protein necessary for the O-acetylation of the Cryptococcus neoformans capsular polysaccharide. Mol Microbiol (2001) 1.74

Structural characterization of the galactoxylomannan of Cryptococcus neoformans Cap67. Carbohydr Res (1998) 1.72

Cell wall composition of the yeastlike and mycelial forms of Blastomyces dermatitidis. J Bacteriol (1971) 1.72

The pathobiology of Paracoccidioides brasiliensis. Trends Microbiol (2002) 1.72

Cryptococcus neoformans STE12alpha regulates virulence but is not essential for mating. J Exp Med (2000) 1.71

Variation in the structure of glucuronoxylomannan in isolates from patients with recurrent cryptococcal meningitis. Infect Immun (1995) 1.70

Organ-dependent variation of capsule thickness in Cryptococcus neoformans during experimental murine infection. Infect Immun (1998) 1.63

Intracellular fate of Cryptococcus neoformans. Infect Immun (1972) 1.63

Altered expression of surface alpha-1,3-glucan in genetically related strains of Blastomyces dermatitidis that differ in virulence. Infect Immun (1994) 1.57

Cell wall dynamics in yeast. Curr Opin Microbiol (1999) 1.57

Aspergillus fumigatus cell wall: composition and biosynthesis. Med Mycol (2001) 1.57

Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors. J Immunol (2002) 1.56

Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans. Eukaryot Cell (2002) 1.55

Chemical characterization of capsular polysaccharide from Cryptococcus neoformans serotype A-D. Microbiol Immunol (1985) 1.54

Binding of cryptococcal polysaccharide to Cryptococcus neoformans. Infect Immun (1984) 1.52

Localization of mannoprotein in Cryptococcus neoformans. J Bacteriol (1989) 1.52

Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans. EMBO Rep (2001) 1.46

Isolation and characterization of capsule structure mutant strains of Cryptococcus neoformans. Mol Microbiol (2002) 1.45

Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans. Proc Natl Acad Sci U S A (2001) 1.44

Cell walls from avirulent variants of Histoplasma capsulatum lack alpha-(1,3)-glucan. Infect Immun (1988) 1.42

Cloning of a Cryptococcus neoformans gene, GPA1, encoding a G-protein alpha-subunit homolog. Infect Immun (1994) 1.39

RNA interference in the pathogenic fungus Cryptococcus neoformans. Genetics (2002) 1.38

Identification of a putative alpha-glucan synthase essential for cell wall construction and morphogenesis in fission yeast. Proc Natl Acad Sci U S A (1998) 1.36

Influence of cryptococcal antigens on cell-mediated immunity. Rev Infect Dis (1988) 1.33

Side group addition by xylosyltransferase and glucuronyltransferase in biosynthesis of capsular polysaccharide in Cryptococcus neoformans. J Med Vet Mycol (1990) 1.32

Paracoccidioides brasiliensis: cell wall structure and virulence. A review. Mycopathologia (1977) 1.32

Detection of melanin-like pigments in the dimorphic fungal pathogen Paracoccidioides brasiliensis in vitro and during infection. Infect Immun (2001) 1.31

Histoplasma capsulatum synthesizes melanin-like pigments in vitro and during mammalian infection. Infect Immun (2002) 1.31

Characterization of protein and mannan polysaccharide antigens of yeasts, moulds, and actinomycetes. Curr Top Med Mycol (1985) 1.30

Mechanisms of bacterial pathogenicity. Postgrad Med J (2002) 1.29

Spatial and temporal sequence of capsule construction in Cryptococcus neoformans. Mol Microbiol (2001) 1.29

Cryptococcus neoformans and cryptococcal glucuronoxylomannan, galactoxylomannan, and mannoprotein induce different levels of tumor necrosis factor alpha in human peripheral blood mononuclear cells. Infect Immun (1997) 1.28

Physical maps for genome analysis of serotype A and D strains of the fungal pathogen Cryptococcus neoformans. Genome Res (2002) 1.27

Microencapsulation of probiotic bacteria: technology and potential applications. Curr Issues Intest Microbiol (2002) 1.24

Binding of purified and radioiodinated capsular polysaccharides from Cryptococcus neoformans serotype A strains to capsule-free mutants. Infect Immun (1986) 1.20

The second STE12 homologue of Cryptococcus neoformans is MATa-specific and plays an important role in virulence. Proc Natl Acad Sci U S A (2001) 1.19

Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase-encoding gene, MAN1, and its impact on pathogenicity. Mol Microbiol (2001) 1.15

Demonstration of a cell wall antigen cross-reacting with cryptococcal polysaccharide in experimental disseminated trichosporonosis. J Clin Microbiol (1991) 1.14

Purification and characterization of a second immunoreactive mannoprotein from Cryptococcus neoformans that stimulates T-Cell responses. Infect Immun (2002) 1.12

UDP glucuronate decarboxylase and synthesis of capsular polysaccharide in Cryptococcus neoformans. J Bacteriol (1982) 1.12

Pathogenicity of Cryptococcus neoformans: virulence factors and immunological mechanisms. Microbes Infect (1999) 1.10

The Cryptococcus neoformans genome sequencing project. Mycopathologia (1999) 1.10

Role of mannoprotein in induction and regulation of immunity to Cryptococcus neoformans. Infect Immun (2001) 1.08

Effect of hypertonic solutes upon the polysaccharide capsule in Cryptococcus neoformans. Mycoses (1989) 1.06

Cell wall biogenesis of Blastomyces dermatitidis. Evidence for a novel mechanism of cell surface localization of a virulence-associated adhesin via extracellular release and reassociation with cell wall chitin. J Biol Chem (2000) 1.03

A survey of heterobasidiomycetous yeasts for the presence of the genes homologous to virulence factors of Filobasidiella neoformans, CNLAC1 and CAP59. Microbiology (2001) 1.02

Fine structural investigation of Malassezia furfur. II. The envelope of the yeast cells. Mycoses (1995) 1.01

An anti-Cryptococcus neoformans monoclonal antibody directed against galactoxylomannan. Res Immunol (1990) 0.97

The yeast cell wall, a dynamic structure engaged in growth and morphogenesis. Biochem Soc Trans (1997) 0.96

Optimization of exopolysaccharide production by Tremella mesenterica NRRL Y-6158 through implementation of fed-batch fermentation. J Ind Microbiol Biotechnol (2002) 0.95

Rhinosporidiosis. Curr Top Med Mycol (1989) 0.94

Studies on capsule synthesis of Cryptococcus neoformans. Sabouraudia (1965) 0.94

Mannoprotein from Cryptococcus neoformans promotes T-helper type 1 anticandidal responses in mice. Infect Immun (2002) 0.93

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