Elaine Wang

Author PubWeight™ 69.99‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lipidomics reveals a remarkable diversity of lipids in human plasma. J Lipid Res 2010 4.14
2 Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry. Methods 2005 3.42
3 Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features. Clin Cancer Res 2006 3.40
4 Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy. Biochim Biophys Acta 2006 3.10
5 Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes 2004 2.86
6 Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers. J Lipid Res 2008 2.62
7 A mouse macrophage lipidome. J Biol Chem 2010 2.14
8 Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. J Biol Chem 2003 2.06
9 Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals. J Biol Chem 2008 1.69
10 Imaging MALDI mass spectrometry using an oscillating capillary nebulizer matrix coating system and its application to analysis of lipids in brain from a mouse model of Tay-Sachs/Sandhoff disease. Anal Chem 2008 1.69
11 Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize. J Nutr 2004 1.64
12 Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics. Methods Enzymol 2007 1.63
13 Non-infectious aortitis: an important cause of severe aortic regurgitation. Asian Cardiovasc Thorac Ann 2006 1.52
14 Combined tetanus, diphtheria, and 5-component pertussis vaccine for use in adolescents and adults. JAMA 2005 1.51
15 Exposure to fumonisins and the occurrence of neural tube defects along the Texas-Mexico border. Environ Health Perspect 2006 1.47
16 Subcellular organelle lipidomics in TLR-4-activated macrophages. J Lipid Res 2010 1.46
17 N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing. Mol Cancer Ther 2008 1.37
18 Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. J Biol Chem 2003 1.32
19 Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. J Biol Chem 2010 1.29
20 Elevation of sulfatides in ovarian cancer: an integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry. Mol Cancer 2010 1.19
21 Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease. J Lipid Res 2008 1.19
22 Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway. Autophagy 2009 1.16
23 The cell surface glycosphingolipids SSEA-3 and SSEA-4 are not essential for human ESC pluripotency. Stem Cells 2006 1.15
24 Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis. J Lipid Res 2007 1.14
25 High resolution analysis of genomic aberrations by metaphase and array comparative genomic hybridization identifies candidate tumour genes in lung cancer cell lines. Cancer Lett 2006 1.13
26 Steroidogenic factor-1 is a sphingolipid binding protein. Mol Cell Endocrinol 2006 1.12
27 Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis. Biochim Biophys Acta 2002 1.08
28 Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action. Pharmacol Res 2003 1.08
29 Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays. Nucleic Acids Res 2005 1.07
30 Cost savings in migraine associated with less chest pain on new triptan therapy. Am J Manag Care 2002 1.07
31 Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide. Mol Cell Biol 2006 1.07
32 Chromosomal aberrations of primary lung adenocarcinomas in nonsmokers. Cancer 2003 1.02
33 Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels. J Biol Chem 2011 0.99
34 In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity. Mol Cancer Ther 2004 0.99
35 A dose-ranging study of a subunit Respiratory Syncytial Virus subtype A vaccine with and without aluminum phosphate adjuvantation in adults > or =65 years of age. Vaccine 2009 0.98
36 Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain. J Biol Chem 2011 0.93
37 Canadian Association for Immunization Research and Evaluation (CAIRE) guidelines for industry-sponsored clinical trial and epidemiology contract research. Hum Vaccin 2005 0.93
38 Prevention of fumonisin B1-induced neural tube defects by folic acid. Teratology 2002 0.89
39 Primary adenocarcinomas of the lung in nonsmokers show a distinct pattern of allelic imbalance. Cancer Res 2002 0.88
40 Activity of faropenem against middle ear fluid pathogens from children with acute otitis media in Costa Rica and Israel. Antimicrob Agents Chemother 2007 0.86
41 Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression. Mol Endocrinol 2012 0.85
42 Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites. Mol Nutr Food Res 2007 0.84
43 Multiple pulmonary metastases from benign pleomorphic adenoma. Asian Cardiovasc Thorac Ann 2008 0.83
44 A rare cause of constrictive pericarditis: primary cardiac lymphoma. Int J Cardiol 2007 0.83
45 Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus. FASEB J 2006 0.82
46 Imaging MALDI mass spectrometry of sphingolipids using an oscillating capillary nebulizer matrix application system. Methods Mol Biol 2010 0.82
47 Treatment and outcome of biopsy-proven fulminant myocarditis in adults. Int J Cardiol 2005 0.81
48 Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor. Mol Cell Biol 2012 0.80
49 Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology. Biochim Biophys Acta 2009 0.78
50 Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction. PLoS One 2012 0.78
51 Computationally predicting rate constants in pathway models. Conf Proc IEEE Eng Med Biol Soc 2005 0.77
52 Bronchiolitis. Clin Evid 2002 0.75
53 Primary cardiac angiosarcoma of left atrium. J Card Surg 2009 0.75
54 Cardiac amyloidosis - experience in a tertiary cardiac referral centre. Int J Cardiol 2007 0.75