The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis.

Moxifloxacin versus ethambutol in the initial treatment of tuberculosis: a double-blind, randomised, controlled phase II trial. Lancet (2009) 5.30

Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis. N Engl J Med (2014) 5.23

Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis. Antimicrob Agents Chemother (2008) 2.33

Combinations of R207910 with drugs used to treat multidrug-resistant tuberculosis have the potential to shorten treatment duration. Antimicrob Agents Chemother (2006) 1.81

Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis. Am J Respir Crit Care Med (2013) 1.65

High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions. Anal Chem (2011) 1.64

Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis. Antimicrob Agents Chemother (2004) 1.52

New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development. Antimicrob Agents Chemother (2008) 1.50

Current development and future prospects in chemotherapy of tuberculosis. Respirology (2010) 1.12

Development of fluoroquinolones as first-line drugs for tuberculosis--at long last! Am J Respir Crit Care Med (2003) 1.09

Correlation between GyrA substitutions and ofloxacin, levofloxacin, and moxifloxacin cross-resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother (2015) 0.96

Assessment of the Efficacy of New Anti-Tuberculosis Drugs. Open Infect Dis J (2008) 0.91

Shortening Tuberculosis Treatment With Fluoroquinolones: Lost in Translation? Clin Infect Dis (2015) 0.84

Powerful bactericidal activity of moxifloxacin in human leprosy. Antimicrob Agents Chemother (2008) 0.82

Efficient intermittent rifapentine-moxifloxacin-containing short-course regimen for treatment of tuberculosis in mice. Antimicrob Agents Chemother (2005) 0.82

New regimens for reducing the duration of the treatment of drug-susceptible pulmonary tuberculosis. Drug Dev Res (2011) 0.80

Moxifloxacin and gatifloxacin for initial therapy of tuberculosis: a meta-analysis of randomized clinical trials. Emerg Microbes Infect (2016) 0.78

Moxifloxacin treatment of tuberculosis. Antimicrob Agents Chemother (2004) 0.78

New drugs and regimens for treatment of TB. Expert Rev Anti Infect Ther (2010) 0.77

Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery. Int J Nanomedicine (2013) 0.77

Accumulating Evidence and Research Organization (AERO) model: a new tool for representing, analyzing, and planning a translational research program. Trials (2013) 0.76

Effect of rifampicin & isoniazid on the steady state pharmacokinetics of moxifloxacin. Indian J Med Res (2012) 0.75

Chemotherapeutic interventions against tuberculosis. Pharmaceuticals (Basel) (2012) 0.75

Gender analysis of moxifloxacin clinical trials. J Womens Health (Larchmt) (2013) 0.75

Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo. Clin Infect Dis (2016) 0.75

Isolation and molecular characterization of Mycobacterium bovis causing pulmonary tuberculosis and epistaxis in a Thoroughbred horse. BMC Vet Res (2016) 0.75

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25

Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science (2011) 7.92

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature (2011) 7.20

A consensus action agenda for achieving the national health information infrastructure. J Am Med Inform Assoc (2004) 5.44

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87

Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus. Arch Intern Med (2005) 4.76

Routine use of microbial whole genome sequencing in diagnostic and public health microbiology. PLoS Pathog (2012) 4.69

Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. J Virol (2011) 4.06

How much of the recent decline in the incidence of myocardial infarction in British men can be explained by changes in cardiovascular risk factors? Evidence from a prospective population-based study. Circulation (2008) 3.13

Innovative trial designs are practical solutions for improving the treatment of tuberculosis. J Infect Dis (2012) 3.09

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03

Social class differences in coronary heart disease in middle-aged British men: implications for prevention. Int J Epidemiol (2004) 2.68

A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosis. Am J Respir Crit Care Med (2015) 2.48

Sarcopenic obesity and risk of cardiovascular disease and mortality: a population-based cohort study of older men. J Am Geriatr Soc (2014) 2.46

Re-assessing the contribution of serum total cholesterol, blood pressure and cigarette smoking to the aetiology of coronary heart disease: impact of regression dilution bias. Eur Heart J (2003) 2.38

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol (2013) 2.18

The role of herpes simplex virus type 2 and other genital infections in the acquisition of HIV-1 among high-risk women in northern Tanzania. J Infect Dis (2007) 2.14

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med (2011) 2.07

Measures of adiposity in the identification of metabolic abnormalities in elderly men. Am J Clin Nutr (2005) 2.07

Interactive computer-based interventions for sexual health promotion. Cochrane Database Syst Rev (2010) 2.04

HIV-1 epidemic among female bar and hotel workers in northern Tanzania: risk factors and opportunities for prevention. J Acquir Immune Defic Syndr (2002) 1.96

Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design. J Virol (2012) 1.86

Issues in multiple imputation of missing data for large general practice clinical databases. Pharmacoepidemiol Drug Saf (2010) 1.85

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. J Natl Cancer Inst (2012) 1.83

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J (2011) 1.73

APOE polymorphism is associated with risk of severe sepsis in surgical patients. Crit Care Med (2005) 1.70

Reconstructing the population genetic history of the Caribbean. PLoS Genet (2013) 1.68

Effects of bed nucleus of the stria terminalis lesions on conditioned anxiety: aversive conditioning with long-duration conditional stimuli and reinstatement of extinguished fear. Behav Neurosci (2006) 1.67

Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants. Am J Clin Nutr (2010) 1.61

Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. Int J Epidemiol (2011) 1.61

Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants. Am J Hum Genet (2006) 1.59

Are childhood socio-economic circumstances related to coronary heart disease risk? Findings from a population-based study of older men. Int J Epidemiol (2007) 1.59

Why Do We Use 600 mg of Rifampicin in Tuberculosis Treatment? Clin Infect Dis (2011) 1.52

Trends in rates of different forms of diagnosed coronary heart disease, 1978 to 2000: prospective, population based study of British men. BMJ (2005) 1.51

Extent of regression dilution for established and novel coronary risk factors: results from the British Regional Heart Study. Eur J Cardiovasc Prev Rehabil (2004) 1.47

Blood pressure loci identified with a gene-centric array. Am J Hum Genet (2011) 1.44

The bacteriology of pleural infection by genetic and standard methods and its mortality significance. Am J Respir Crit Care Med (2006) 1.44

X-APL: an improved family-based test of association in the presence of linkage for the X chromosome. Am J Hum Genet (2006) 1.44

Novel PCR-restriction fragment length polymorphism method for determining serotypes or serogroups of Streptococcus pneumoniae isolates. J Clin Microbiol (2005) 1.44

Secondary prevention of coronary heart disease in older patients after the national service framework: population based study. BMJ (2006) 1.42

Evolutionary relationships among strains of Mycobacterium tuberculosis with few copies of IS6110. J Bacteriol (2003) 1.41

Blood culture bottle culture of pleural fluid in pleural infection. Thorax (2011) 1.40

HIV among pregnant women in Moshi Tanzania: the role of sexual behavior, male partner characteristics and sexually transmitted infections. AIDS Res Ther (2006) 1.37

Herpes simplex virus type 2 infection among bar and hotel workers in northern Tanzania: prevalence and risk factors. Sex Transm Dis (2003) 1.35

Exercise for reducing fear of falling in older people living in the community. Cochrane Database Syst Rev (2014) 1.33

Biomarkers of treatment response in clinical trials of novel antituberculosis agents. Lancet Infect Dis (2007) 1.32

Early versus delayed fixed dose combination abacavir/lamivudine/zidovudine in patients with HIV and tuberculosis in Tanzania. AIDS Res Hum Retroviruses (2009) 1.32

Analysis of rpoB and pncA mutations in the published literature: an insight into the role of oxidative stress in Mycobacterium tuberculosis evolution? J Antimicrob Chemother (2005) 1.30

Nicotinamide adenine dinucleotide (phosphate) reduced:quinone oxidoreductase and glutathione S-transferase M1 polymorphisms and childhood asthma. Am J Respir Crit Care Med (2003) 1.28

Patterns of alcohol use, problem drinking, and HIV infection among high-risk African women. Sex Transm Dis (2008) 1.27

Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery. J Am Coll Cardiol (2007) 1.27

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target. Proc Natl Acad Sci U S A (2012) 1.26

Prevalence of sexually transmitted infections among pregnant women with known HIV status in northern Tanzania. Reprod Health (2009) 1.25

Sequetyping: serotyping Streptococcus pneumoniae by a single PCR sequencing strategy. J Clin Microbiol (2012) 1.24

Predictors of failure to return for HIV test results among pregnant women in Moshi, Tanzania. J Acquir Immune Defic Syndr (2006) 1.24

Female genital cutting in Kilimanjaro, Tanzania: changing attitudes? Trop Med Int Health (2002) 1.21

Prevalence and risk factors for HIV-1 infection in rural Kilimanjaro region of Tanzania: implications for prevention and treatment. BMC Public Health (2007) 1.21

Human immunodeficiency virus type 1 among bar and hotel workers in northern Tanzania: the role of alcohol, sexual behavior, and herpes simplex virus type 2. Sex Transm Dis (2006) 1.21

Rising adiposity curbing decline in the incidence of myocardial infarction: 20-year follow-up of British men and women in the Whitehall II cohort. Eur Heart J (2011) 1.18

Short report: asymptomatic Cryptosporidium hominis infection among human immunodeficiency virus-infected patients in Tanzania. Am J Trop Med Hyg (2005) 1.17

Extent of social inequalities in disability in the elderly: results from a population-based study of British men. Ann Epidemiol (2008) 1.17

Impact of azithromycin administration for trachoma control on the carriage of antibiotic-resistant Streptococcus pneumoniae. Antimicrob Agents Chemother (2003) 1.16

Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta Trop (2007) 1.16

Adolescent rats are protected from the conditioned aversive properties of cocaine and lithium chloride. Pharmacol Biochem Behav (2006) 1.16

Anopheline larval habitats seasonality and species distribution: a prerequisite for effective targeted larval habitats control programmes. PLoS One (2012) 1.15

Contextual control of inhibition with reinforcement: adaptation and timing mechanisms. J Exp Psychol Anim Behav Process (2008) 1.15

Mortality, morbidity, and 1-year outcomes of primary elective total hip arthroplasty. J Arthroplasty (2002) 1.13

Predation efficiency of Anopheles gambiae larvae by aquatic predators in western Kenya highlands. Parasit Vectors (2011) 1.12

PTPN22 and invasive bacterial disease. Nat Genet (2006) 1.12

IkappaB genetic polymorphisms and invasive pneumococcal disease. Am J Respir Crit Care Med (2007) 1.11

Design issues in pivotal drug trials for drug sensitive tuberculosis (TB). Tuberculosis (Edinb) (2008) 1.08

Deterioration of regional wall motion immediately after coronary artery bypass graft surgery is associated with long-term major adverse cardiac events. Anesthesiology (2007) 1.05

Molecular bacterial load assay, a culture-free biomarker for rapid and accurate quantification of sputum Mycobacterium tuberculosis bacillary load during treatment. J Clin Microbiol (2011) 1.05

A practical guide to measuring mutation rates in antibiotic resistance. Antimicrob Agents Chemother (2008) 1.05

Length of the QT interval: determinants and prognostic implications in a population-based prospective study of older men. J Electrocardiol (2008) 1.04

A Community-based study of risk factors for Trichomonas vaginalis infection among women and their male partners in Moshi urban district, northern Tanzania. Sex Transm Dis (2006) 1.04

Durability associated efficacy of long-lasting insecticidal nets after five years of household use. Parasit Vectors (2011) 1.03

Impact of cotrimoxazole on carriage and antibiotic resistance of Streptococcus pneumoniae and Haemophilus influenzae in HIV-infected children in Zambia. Antimicrob Agents Chemother (2010) 1.03

Phylogeography and demographic history of Amblyomma variegatum (Fabricius) (Acari: Ixodidae), the tropical bont tick. Vector Borne Zoonotic Dis (2012) 1.02

Effects of co-habitation between Anopheles gambiae s.s. and Culex quinquefasciatus aquatic stages on life history traits. Parasit Vectors (2012) 1.01

Predicting CD4 lymphocyte count <200 cells/mm(3) in an HIV type 1-infected African population. AIDS Res Hum Retroviruses (2007) 1.01

The role of in-migrants in the increasing rural HIV-1 epidemic: results from a village population survey in the Kilimanjaro region of Tanzania. Int J Infect Dis (2008) 1.01

Evaluation of two-fold fully conditional specification multiple imputation for longitudinal electronic health record data. Stat Med (2014) 1.00

High diet quality is associated with a lower risk of cardiovascular disease and all-cause mortality in older men. J Nutr (2014) 1.00

Is the recent rise in type 2 diabetes incidence from 1984 to 2007 explained by the trend in increasing BMI?: evidence from a prospective study of British men. Diabetes Care (2010) 1.00

Early bactericidal activity of a moxifloxacin and isoniazid combination in smear-positive pulmonary tuberculosis. J Antimicrob Chemother (2005) 1.00

Design of a community-based study of sexually transmitted infections/HIV and infertility in an urban area of northern Tanzania. Sex Transm Dis (2007) 0.99

Trends in HIV-1 prevalence and risk behaviours over 15 years in a rural population in Kilimanjaro region of Tanzania. AIDS Res Ther (2007) 0.99

Relationships of inflammatory and haemostatic markers with social class: results from a population-based study of older men. Atherosclerosis (2007) 0.99

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circ Cardiovasc Genet (2011) 0.99

High prevalence of Entamoeba moshkovskii in a Tanzanian HIV population. Acta Trop (2008) 0.98

Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now! Int J Antimicrob Agents (2010) 0.97

Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery. Psychosom Med (2008) 0.96

How well do HapMap haplotypes identify common haplotypes of genes? A comparison with haplotypes of 334 genes resequenced in the environmental genome project. Cancer Epidemiol Biomarkers Prev (2006) 0.96

Trends in longer-term survival following an acute myocardial infarction and prescribing of evidenced-based medications in primary care in the UK from 1991: a longitudinal population-based study. J Epidemiol Community Health (2010) 0.96

Origins and properties of Mycobacterium tuberculosis isolates in London. J Med Microbiol (2005) 0.96

Genetic polymorphisms and the risk of stroke after cardiac surgery. Stroke (2005) 0.96