| Rank | Title | Journal | Year | PubWeight™‹?› |
|---|---|---|---|---|
| 1 | Structure-based design of aliskiren, a novel orally effective renin inhibitor. | Biochem Biophys Res Commun | 2003 | 1.74 |
| 2 | Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosets. | J Med Chem | 2007 | 0.92 |
| 3 | Novel 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamide transition state peptidomimetics are potent and orally active inhibitors of human renin. | J Med Chem | 2007 | 0.75 |