PubRank

William M Abraham

Author PubWeight™ 41.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Aerosolized red-tide toxins (brevetoxins) and asthma. Chest 2007 2.70
2 The porcine lung as a potential model for cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 2008 2.53
3 Low-volume resuscitation from traumatic hemorrhagic shock with Na+/H+ exchanger inhibitor. Crit Care Med 2009 1.41
4 Resuscitation with Na+/H+ exchanger inhibitor in traumatic haemorrhagic shock: cardiopulmonary performance, oxygen transport and tissue inflammation. Clin Exp Pharmacol Physiol 2009 1.39
5 Review of Florida Red Tide and Human Health Effects. Harmful Algae 2011 1.12
6 Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease. J Pharmacol Exp Ther 2008 1.11
7 Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease. J Pharmacol Exp Ther 2004 1.05
8 Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib. J Med Chem 2008 1.03
9 Exposure and effect assessment of aerosolized red tide toxins (brevetoxins) and asthma. Environ Health Perspect 2009 1.00
10 Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone. J Med Chem 2003 0.96
11 Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo. PLoS One 2010 0.95
12 Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524). J Med Chem 2007 0.95
13 An Epidemiologic Approach to the Study of Aerosolized Florida Red Tides. Harmful Algae 2002 (2002) 1 0.94
14 Tryptase: potential role in airway inflammation and remodeling. Am J Physiol Lung Cell Mol Physiol 2002 0.94
15 Efficacy of IL-13 neutralization in a sheep model of experimental asthma. Am J Respir Cell Mol Biol 2006 0.93
16 Synthesis, modeling, and biological evaluation of analogues of the semisynthetic brevetoxin antagonist beta-naphthoyl-brevetoxin. Chembiochem 2007 0.93
17 Dual inhibition of cathepsin G and chymase is effective in animal models of pulmonary inflammation. Am J Respir Crit Care Med 2009 0.92
18 Hyaluronan blocks human neutrophil elastase (HNE)-induced airway responses in sheep. Pulm Pharmacol Ther 2003 0.91
19 Characterization of tamulamides A and B, polyethers isolated from the marine dinoflagellate Karenia brevis. J Nat Prod 2010 0.91
20 Therapeutic targeting of endothelial ligands for L-selectin (PNAd) in a sheep model of asthma. Am J Pathol 2005 0.88
21 Na+/H+ exchange inhibition delays the onset of hypovolemic circulatory shock in pigs. Shock 2008 0.87
22 Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction. Am J Respir Cell Mol Biol 2013 0.86
23 Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. Am J Physiol Lung Cell Mol Physiol 2013 0.85
24 Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy. Bioorg Med Chem 2007 0.85
25 Comparative effects of salmeterol, albuterol, and ipratropium on normal and impaired mucociliary function in sheep. Chest 2005 0.85
26 Aerosolized Red Tide Toxins (Brevetoxins) and Asthma: Continued health effects after 1 hour beach exposure. Harmful Algae 2011 0.84
27 Leukocytic cell sources of airway tissue kallikrein. Am J Physiol Lung Cell Mol Physiol 2003 0.84
28 Recombinant alpha 1-proteinase inhibitor blocks antigen- and mediator-induced airway responses in sheep. J Appl Physiol (1985) 2002 0.84
29 Preclinical evaluation of an inhibitor of cytosolic phospholipase A2α for the treatment of asthma. J Pharmacol Exp Ther 2011 0.83
30 Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in acute metabolic acidosis in pigs. PLoS One 2013 0.83
31 Identification of potent and novel alpha4beta1 antagonists using in silico screening. J Med Chem 2002 0.82
32 Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist. Mol Pharmacol 2010 0.82
33 Montelukast prevents antigen-induced mucociliary dysfunction in sheep. Am J Respir Crit Care Med 2002 0.80
34 Hyaluronan blocks porcine pancreatic elastase-induced mucociliary dysfunction in allergic sheep. J Appl Physiol (1985) 2007 0.80
35 Effect of oral and intravenous heparin tetrasaccharide on allergic airway responses: critical role of N-sulfation. Pulm Pharmacol Ther 2012 0.80
36 NHE1 inhibition improves tissue perfusion and resuscitation outcome after severe hemorrhage. J Surg Res 2012 0.80
37 Repeated exposure to aerosolized brevetoxin-3 induces prolonged airway hyperresponsiveness and lung inflammation in sheep. Inhal Toxicol 2011 0.79
38 Florida Red Tide Toxins (Brevetoxins) and Longitudinal Respiratory Effects in Asthmatics. Harmful Algae 2011 0.79
39 Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases. Biochem J 2009 0.79
40 Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives. Bioorg Med Chem Lett 2008 0.78
41 Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agent. Bioorg Med Chem 2006 0.77
42 Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence. Respir Res 2012 0.77
43 Aza-bicyclic amino acid sulfonamides as alpha(4)beta(1)/alpha(4)beta(7) integrin antagonists. Bioorg Med Chem Lett 2004 0.75