Role of inhibitory amino acids in control of hypoglossal motor outflow to genioglossus muscle in naturally sleeping rats.

PubWeight™: 1.26‹?› | Rank: Top 10%

🔗 View Article (PMC 2343458)

Published in J Physiol on August 22, 2003

Authors

Janna L Morrison1, Sandeep Sood, Hattie Liu, Eileen Park, Xia Liu, Philip Nolan, Richard L Horner

Author Affiliations

1: Departments of Medicine and Physiology, University of Toronto, Toronto, Canada M5S 1A8.

Articles citing this

Pathophysiology of sleep apnea. Physiol Rev (2010) 4.69

Control of sleep and wakefulness. Physiol Rev (2012) 3.06

REM sleep-like atonia of hypoglossal (XII) motoneurons is caused by loss of noradrenergic and serotonergic inputs. Am J Respir Crit Care Med (2005) 1.89

Genioglossus premotoneurons and the negative pressure reflex in rats. J Physiol (2006) 1.28

Sleep neurobiology from a clinical perspective. Sleep (2011) 1.14

Influence of wakefulness on pharyngeal airway muscle activity. Thorax (2007) 1.12

Central and peripheral factors contributing to obstructive sleep apneas. Respir Physiol Neurobiol (2013) 1.10

State-dependent and reflex drives to the upper airway: basic physiology with clinical implications. J Appl Physiol (1985) (2013) 0.99

Opposing muscarinic and nicotinic modulation of hypoglossal motor output to genioglossus muscle in rats in vivo. J Physiol (2005) 0.96

Emerging principles and neural substrates underlying tonic sleep-state-dependent influences on respiratory motor activity. Philos Trans R Soc Lond B Biol Sci (2009) 0.95

Unraveling the mechanisms of REM sleep atonia. Sleep (2008) 0.92

Adventures and tribulations in the search for the mechanisms of the atonia of REM sleep. Sleep (2008) 0.91

Electromyographic activity at the base and tip of the tongue across sleep-wake states in rats. Respir Physiol Neurobiol (2009) 0.91

Glycine-mediated postsynaptic inhibition is responsible for REM sleep atonia. Sleep (2008) 0.90

Differential effects of isoflurane and propofol on upper airway dilator muscle activity and breathing. Anesthesiology (2008) 0.90

Are all motoneurons created equal in the eyes of REM sleep and the mechanisms of muscle atonia? Sleep (2008) 0.90

What causes muscle atonia in REM? Sleep (2008) 0.89

Behavioral response and transmitter release during atonia elicited by medial medullary stimulation. J Neurophysiol (2010) 0.85

Development of synaptic transmission to respiratory motoneurons. Respir Physiol Neurobiol (2011) 0.85

Respiratory related control of hypoglossal motoneurons--knowing what we do not know. Respir Physiol Neurobiol (2011) 0.84

Evidence that adrenergic ventrolateral medullary cells are activated whereas precerebellar lateral reticular nucleus neurons are suppressed during REM sleep. PLoS One (2013) 0.81

Role of inhibitory neurotransmission in the control of canine hypoglossal motoneuron activity in vivo. J Neurophysiol (2008) 0.81

Quantitative differences among EMG activities of muscles innervated by subpopulations of hypoglossal and upper spinal motoneurons during non-REM sleep - REM sleep transitions: a window on neural processes in the sleeping brain. Arch Ital Biol (2011) 0.80

Revisiting Antagonist Effects in Hypoglossal Nucleus: Brainstem Circuit for the State-Dependent Control of Hypoglossal Motoneurons: A Hypothesis. Front Neurol (2015) 0.80

Circadian dependence of receptors that mediate wake-related excitatory drive to hypoglossal motoneurons. Respir Physiol Neurobiol (2013) 0.80

Sleep-wake control of the upper airway by noradrenergic neurons, with and without intermittent hypoxia. Prog Brain Res (2014) 0.78

Neural Control of the Upper Airway: Respiratory and State-Dependent Mechanisms. Compr Physiol (2016) 0.78

Quantitative analysis of the excitability of hypoglossal motoneurons during natural sleep in the rat. J Neurosci Methods (2012) 0.76

The anatomical, cellular and synaptic basis of motor atonia during rapid eye movement sleep. J Physiol (2016) 0.75

Catecholaminergic A1/C1 neurons contribute to the maintenance of upper airway muscle tone but may not participate in NREM sleep-related depression of these muscles. Respir Physiol Neurobiol (2017) 0.75

Articles cited by this

The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med (1993) 35.93

Pathogenesis of upper airway occlusion during sleep. J Appl Physiol Respir Environ Exerc Physiol (1978) 5.48

Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci (1981) 4.15

The human tongue during sleep: electromyographic activity of the genioglossus muscle. Exp Neurol (1976) 2.19

Respiratory rhythm generation and synaptic inhibition of expiratory neurons in pre-Bötzinger complex: differential roles of glycinergic and GABAergic neural transmission. J Neurophysiol (1997) 1.60

Development of glycinergic synaptic transmission to rat brain stem motoneurons. J Neurophysiol (1998) 1.59

Raphe unit activity in freely moving cats: correlation with level of behavioral arousal. Brain Res (1979) 1.59

Cotransmission of GABA and glycine to brain stem motoneurons. J Neurophysiol (1999) 1.55

Effects of sleep-wake state on the genioglossus vs.diaphragm muscle response to CO(2) in rats. J Appl Physiol (1985) (2002) 1.49

Unitary characteristics of presumptive cholinergic tegmental neurons during the sleep-waking cycle in freely moving cats. Exp Brain Res (1989) 1.36

Presynaptic depression of excitatory synaptic inputs to rat hypoglossal motoneurons by muscarinic M2 receptors. J Neurophysiol (1996) 1.31

Changes in monoamine release in the ventral horn and hypoglossal nucleus linked to pontine inhibition of muscle tone: an in vivo microdialysis study. J Neurosci (2001) 1.28

Control of Upper Airway Motoneurons During REM Sleep. News Physiol Sci (1998) 1.25

Changes in inhibitory amino acid release linked to pontine-induced atonia: an in vivo microdialysis study. J Neurosci (2003) 1.21

Microdialysis perfusion of 5-HT into hypoglossal motor nucleus differentially modulates genioglossus activity across natural sleep-wake states in rats. J Physiol (2001) 1.19

Changes in upper airway muscle activation and ventilation during phasic REM sleep in normal men. J Appl Physiol (1985) (1991) 1.18

Intracellular analysis of respiratory-modulated hypoglossal motoneurons in the cat. Neuroscience (1988) 1.16

Evidence that glycine mediates the postsynaptic potentials that inhibit lumbar motoneurons during the atonia of active sleep. J Neurosci (1989) 1.14

Motoneuron properties during motor inhibition produced by microinjection of carbachol into the pontine reticular formation of the decerebrate cat. J Neurophysiol (1987) 1.12

Suppression of hypoglossal motoneurons during the carbachol-induced atonia of REM sleep is not caused by fast synaptic inhibition. Brain Res (1993) 1.12

Effect of pulmonary stretch receptor feedback and CO(2) on upper airway and respiratory pump muscle activity in the rat. J Physiol (2001) 1.11

The postsynaptic inhibitory control of lumbar motoneurons during the atonia of active sleep: effect of strychnine on motoneuron properties. J Neurosci (1991) 1.11

GABAA receptor antagonism at the hypoglossal motor nucleus increases genioglossus muscle activity in NREM but not REM sleep. J Physiol (2003) 1.11

Relative contribution by GABA or glycine to Cl(-)-mediated synaptic transmission on rat hypoglossal motoneurons in vitro. J Neurophysiol (2000) 1.08

Hypoglossal motoneurons are postsynaptically inhibited during carbachol-induced rapid eye movement sleep. Neuroscience (1999) 1.08

Respiratory roles of genioglossus, sternothyroid, and sternohyoid muscles during sleep. Exp Neurol (1985) 1.06

Respiratory control of hypoglossal motoneurones in the rat. Pflugers Arch (2001) 1.06

Subthreshold excitatory activity and motoneuron discharge during REM periods of active sleep. Science (1983) 1.04

Distribution of GABAergic and glycinergic premotor neurons projecting to the facial and hypoglossal nuclei in the rat. J Comp Neurol (1997) 1.02

Presynaptic inhibition by serotonin of glycinergic inhibitory synaptic currents in the rat brain stem. J Neurophysiol (1995) 1.01

Membrane potential of spinal motoneurons during natural sleep in cats. Sleep (1978) 0.99

Nicotinic excitation of rat hypoglossal motoneurons. Neuroscience (2002) 0.98

Behaviour of raphe cells projecting to the dorsomedial medulla during carbachol-induced atonia in the cat. J Physiol (1996) 0.98

Changes in electrophysiological properties of cat hypoglossal motoneurons during carbachol-induced motor inhibition. Brain Res (2000) 0.97

The neuropharmacology of upper airway motor control in the awake and asleep states: implications for obstructive sleep apnoea. Respir Res (2001) 0.97

Changes in serotonin level in the hypoglossal nucleus region during carbachol-induced atonia. Brain Res (1994) 0.95

Presence of functional neuronal nicotinic acetylcholine receptors in brainstem motoneurons of the rat. Eur J Neurosci (1999) 0.95

Glycine at hypoglossal motor nucleus: genioglossus activity, CO(2) responses, and the additive effects of GABA. J Appl Physiol (1985) (2002) 0.93

Effect of inhibitory amino acid antagonists on masseteric reflex suppression during active sleep. Exp Neurol (1987) 0.92

Non-reciprocal control of rhythmic activity in respiratory-modulated XII motoneurons. Neuroreport (1995) 0.90

Oropharyngeal muscle tone in obstructive sleep apnea before and after strychnine. Sleep (1980) 0.90

Endogenous excitatory drive to the respiratory system in rapid eye movement sleep in cats. J Physiol (2000) 0.88

Correlation between genioglossal and diaphragmatic responses to hypercapnia during sleep. Am Rev Respir Dis (1987) 0.88

Respiratory-related activity in hypoglossal neurons across sleep-waking states in cats. Brain Res (1991) 0.87

State-related inhibition by GABA and glycine of transmission in Clarke's column. J Neurosci (2002) 0.87

Suppression of genioglossus muscle tone and activity during reflex hypercapnic stimulation by GABA(A) mechanisms at the hypoglossal motor nucleus in vivo. Neuroscience (2003) 0.86

Determinants of respiratory motoneuron output. Respir Physiol (2000) 0.85

Role of medullary reticular neurons in the inhibition of trigeminal motoneurons during active sleep. Exp Neurol (1984) 0.85

Two components of inhibitory postsynaptic potentials evoked in hypoglossal motoneurons by lingual nerve stimulation. Exp Neurol (1980) 0.81

Pharmacotherapies for obstructive sleep apnea: how close are we? Curr Opin Pulm Med (2001) 0.80

Strychnine blocks inhibitory postsynaptic potentials elicited in masseter motoneurons by sensory stimuli during carbachol-induced motor atonia. Neuroscience (1997) 0.78

Articles by these authors

MYD88 L265P somatic mutation in Waldenström's macroglobulinemia. N Engl J Med (2012) 4.26

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proc Natl Acad Sci U S A (2010) 2.57

Relevance of surgical strategies for the management of pediatric Chiari type I malformation. Childs Nerv Syst (2007) 2.35

Effect of 7,8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning. Am J Psychiatry (2010) 2.25

Data-mining approaches reveal hidden families of proteases in the genome of malaria parasite. Genome Res (2003) 2.18

Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation. Cell Stem Cell (2013) 2.12

Proteomics approach reveals novel proteins on the surface of malaria-infected erythrocytes. Mol Biochem Parasitol (2004) 1.96

Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis. Arthritis Res Ther (2010) 1.90

Somatic mutations in MYD88 and CXCR4 are determinants of clinical presentation and overall survival in Waldenstrom macroglobulinemia. Blood (2014) 1.89

Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2. J Immunol (2009) 1.85

Epilepsy surgery outcome in children with tuberous sclerosis complex evaluated with alpha-[11C]methyl-L-tryptophan positron emission tomography (PET). J Child Neurol (2005) 1.82

Identification of the mechanism mediating genioglossus muscle suppression in REM sleep. Am J Respir Crit Care Med (2012) 1.79

MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction. Blood (2013) 1.79

Antishock effect of anisodamine involves a novel pathway for activating alpha7 nicotinic acetylcholine receptor. Crit Care Med (2009) 1.72

Role of subdural electrocorticography in prediction of long-term seizure outcome in epilepsy surgery. Brain (2009) 1.68

Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. EMBO J (2006) 1.67

Clinical significance and developmental changes of auditory-language-related gamma activity. Clin Neurophysiol (2012) 1.66

Multimodality language mapping in patients with left-hemispheric language dominance on Wada test. Clin Neurophysiol (2012) 1.66

Somatosensory-related gamma-, beta- and alpha-augmentation precedes alpha- and beta-attenuation in humans. Clin Neurophysiol (2010) 1.62

Application of 1H NMR-based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis. Cancer Sci (2009) 1.60

In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification. J Bone Joint Surg Am (2003) 1.59

Colonic leptin: source of a novel proinflammatory cytokine involved in IBD. FASEB J (2004) 1.58

Role of endogenous serotonin in modulating genioglossus muscle activity in awake and sleeping rats. Am J Respir Crit Care Med (2005) 1.56

Anion-modulated reversible conversion of molecular assembly between a macrocycle and a linear chain. Inorg Chem (2008) 1.54

Gamma activity modulated by picture and auditory naming tasks: intracranial recording in patients with focal epilepsy. Clin Neurophysiol (2013) 1.51

Effects of sleep-wake state on the genioglossus vs.diaphragm muscle response to CO(2) in rats. J Appl Physiol (1985) (2002) 1.49

Origin and propagation of epileptic spasms delineated on electrocorticography. Epilepsia (2005) 1.45

In vivo animation of auditory-language-induced gamma-oscillations in children with intractable focal epilepsy. Neuroimage (2008) 1.45

A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia. Blood (2013) 1.44

Remission of rheumatoid arthritis and potential determinants: a national multi-center cross-sectional survey. Clin Rheumatol (2014) 1.41

Short-latency median-nerve somatosensory-evoked potentials and induced gamma-oscillations in humans. Brain (2008) 1.40

Endogenous excitatory drive modulating respiratory muscle activity across sleep-wake states. Am J Respir Crit Care Med (2006) 1.39

The genomic landscape of Waldenstrom macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis. Blood (2013) 1.38

Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells. J Exp Med (2011) 1.37

Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation. EMBO J (2005) 1.35

Spontaneous and visually driven high-frequency oscillations in the occipital cortex: intracranial recording in epileptic patients. Hum Brain Mapp (2011) 1.35

Quantitative interictal subdural EEG analyses in children with neocortical epilepsy. Epilepsia (2003) 1.33

Imaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors. Mol Imaging Biol (2009) 1.30

Isolation and characterization of a new ginsenoside from the fresh root of Panax Ginseng. Molecules (2010) 1.30

N-acetylserotonin activates TrkB receptor in a circadian rhythm. Proc Natl Acad Sci U S A (2010) 1.28

Effect of neuraminidase on receptor-mediated adherence of Streptococcus pneumoniae to chinchilla tracheal epithelium. Acta Otolaryngol (2002) 1.27

In vivo uptake and metabolism of alpha-[11C]methyl-L-tryptophan in human brain tumors. J Cereb Blood Flow Metab (2006) 1.26

Pyrosequencing analysis of the human microbiota of healthy Chinese undergraduates. BMC Genomics (2013) 1.26

PreBotzinger complex neurokinin-1 receptor-expressing neurons mediate opioid-induced respiratory depression. J Neurosci (2011) 1.25

Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. Mol Cell (2008) 1.25

Energy landscape analysis of native folding of the prion protein yields the diffusion constant, transition path time, and rates. Proc Natl Acad Sci U S A (2012) 1.24

Ebp1 isoforms distinctively regulate cell survival and differentiation. Proc Natl Acad Sci U S A (2006) 1.23

Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib. Clin Cancer Res (2005) 1.23

Automated processing of the single-lead electrocardiogram for the detection of obstructive sleep apnoea. IEEE Trans Biomed Eng (2003) 1.20

γ-oscillations modulated by picture naming and word reading: intracranial recording in epileptic patients. Clin Neurophysiol (2011) 1.19

A critical role of mitochondrial phosphatase Ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells. Mol Cell Biol (2011) 1.18

Nucleophosmin/B23, a nuclear PI(3,4,5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD. Mol Cell (2005) 1.18

Stromal derived factor-1 regulates bone morphogenetic protein 2-induced osteogenic differentiation of primary mesenchymal stem cells. Int J Biochem Cell Biol (2010) 1.17

Superhydrophobic and superoleophilic PVDF membranes for effective separation of water-in-oil emulsions with high flux. Adv Mater (2013) 1.16

Development and application of a set of breeder-friendly SNP markers for genetic analyses and molecular breeding of rice (Oryza sativa L.). Theor Appl Genet (2011) 1.16

Statistical mapping of ictal high-frequency oscillations in epileptic spasms. Epilepsia (2010) 1.16

MicroRNA-124 mediates the cholinergic anti-inflammatory action through inhibiting the production of pro-inflammatory cytokines. Cell Res (2013) 1.15

Metabonomic profiling of renal cell carcinoma: high-resolution proton nuclear magnetic resonance spectroscopy of human serum with multivariate data analysis. Anal Chim Acta (2008) 1.14

A WRKY transcription factor participates in dehydration tolerance in Boea hygrometrica by binding to the W-box elements of the galactinol synthase (BhGolS1) promoter. Planta (2009) 1.14

Expression of c-Jun, p73, Casp9, and N-ras in thymic epithelial tumors: relationship with the current WHO classification systems. Diagn Pathol (2012) 1.14

Circulating Dickkopf-1 is correlated with bone erosion and inflammation in rheumatoid arthritis. J Rheumatol (2011) 1.14

Opioid receptor mechanisms at the hypoglossal motor pool and effects on tongue muscle activity in vivo. J Physiol (2009) 1.13

Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis. Clin Cancer Res (2004) 1.13

Epidemiology of eight common rheumatic diseases in China: a large-scale cross-sectional survey in Beijing. Rheumatology (Oxford) (2011) 1.12

Altered fecal microbiota composition associated with food allergy in infants. Appl Environ Microbiol (2014) 1.11

Differential visually-induced gamma-oscillations in human cerebral cortex. Neuroimage (2008) 1.11

GABAA receptor antagonism at the hypoglossal motor nucleus increases genioglossus muscle activity in NREM but not REM sleep. J Physiol (2003) 1.11

Young patients with focal seizures may have the primary motor area for the hand in the postcentral gyrus. Epilepsy Res (2007) 1.10

Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons. J Biol Chem (2009) 1.10

A common pattern of persistent gene activation in human neocortical epileptic foci. Ann Neurol (2005) 1.10

Direct observation of multiple misfolding pathways in a single prion protein molecule. Proc Natl Acad Sci U S A (2012) 1.08

Phosphoinositide 3-kinase enhancer regulates neuronal dendritogenesis and survival in neocortex. J Neurosci (2011) 1.08

Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease. Hum Mol Genet (2013) 1.08

Near-infrared light-triggered, targeted drug delivery to cancer cells by aptamer gated nanovehicles. Adv Mater (2012) 1.08

Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE. J Biol Chem (2002) 1.07

Cortical gamma-oscillations modulated by listening and overt repetition of phonemes. Neuroimage (2009) 1.07

MCPIP1 down-regulates IL-2 expression through an ARE-independent pathway. PLoS One (2012) 1.06

Pentobarbital sedation increases genioglossus respiratory activity in sleeping rats. Sleep (2007) 1.06

Comparison of bupivacaine, ropivacaine and levobupivacaine with sufentanil for patient-controlled epidural analgesia during labor: a randomized clinical trial. Chin Med J (Engl) (2010) 1.06

Objective detection of epileptic foci by 18F-FDG PET in children undergoing epilepsy surgery. J Nucl Med (2010) 1.05

Simulation of soil loss processes based on rainfall runoff and the time factor of governance in the Jialing River Watershed, China. Environ Monit Assess (2011) 1.04

Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor. Mol Biol Cell (2008) 1.03

The role of intestinal mucosa injury induced by intra-abdominal hypertension in the development of abdominal compartment syndrome and multiple organ dysfunction syndrome. Crit Care (2013) 1.03

Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity. Chem Biol (2009) 1.03

N-acetyl serotonin derivatives as potent neuroprotectants for retinas. Proc Natl Acad Sci U S A (2012) 1.02

Cajanol, a novel anticancer agent from Pigeonpea [Cajanus cajan (L.) Millsp.] roots, induces apoptosis in human breast cancer cells through a ROS-mediated mitochondrial pathway. Chem Biol Interact (2010) 1.02

MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway. J Biol Chem (2008) 1.02

Diversity of cervicovaginal microbiota associated with female lower genital tract infections. Microb Ecol (2011) 1.01