Published in J Gen Physiol on September 01, 2003
ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification. Proc Natl Acad Sci U S A (2009) 2.61
Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons. Neuron (2005) 2.38
TMEM16B induces chloride currents activated by calcium in mammalian cells. Pflugers Arch (2009) 2.20
Bestrophin-2 is a candidate calcium-activated chloride channel involved in olfactory transduction. Proc Natl Acad Sci U S A (2006) 1.68
Clustering of cyclic-nucleotide-gated channels in olfactory cilia. Biophys J (2006) 1.41
Molecular components of signal amplification in olfactory sensory cilia. Proc Natl Acad Sci U S A (2010) 1.39
Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels. J Gen Physiol (2013) 1.30
TMEM16A channels generate Ca²⁺-activated Cl⁻ currents in cerebral artery smooth muscle cells. Am J Physiol Heart Circ Physiol (2011) 1.29
Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation. Neuron (2008) 1.26
Calcium concentration jumps reveal dynamic ion selectivity of calcium-activated chloride currents in mouse olfactory sensory neurons and TMEM16b-transfected HEK 293T cells. J Physiol (2010) 1.24
Loss of CNGB1 protein leads to olfactory dysfunction and subciliary cyclic nucleotide-gated channel trapping. J Biol Chem (2006) 1.20
Altered expression of Ano1 variants in human diabetic gastroparesis. J Biol Chem (2011) 1.19
Phosphodiesterase 1C is dispensable for rapid response termination of olfactory sensory neurons. Nat Neurosci (2009) 1.19
Fast adaptation in mouse olfactory sensory neurons does not require the activity of phosphodiesterase. J Gen Physiol (2006) 1.15
Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches. J Gen Physiol (2006) 1.13
Model of calcium oscillations due to negative feedback in olfactory cilia. Biophys J (2005) 1.12
Modulation of chloride homeostasis by inflammatory mediators in dorsal root ganglion neurons. Mol Pain (2008) 1.11
Neuronal chloride accumulation in olfactory epithelium of mice lacking NKCC1. J Neurophysiol (2005) 1.09
Calmodulin contributes to gating control in olfactory calcium-activated chloride channels. J Gen Physiol (2006) 1.03
Location of release sites and calcium-activated chloride channels relative to calcium channels at the photoreceptor ribbon synapse. J Neurophysiol (2010) 1.02
Computational model of the insect pheromone transduction cascade. PLoS Comput Biol (2009) 1.01
Calcium-activated chloride channels in the apical region of mouse vomeronasal sensory neurons. J Gen Physiol (2012) 1.01
Calcium-activated chloride currents in olfactory sensory neurons from mice lacking bestrophin-2. J Physiol (2009) 0.99
Activation and inhibition of TMEM16A calcium-activated chloride channels. PLoS One (2014) 0.97
Mitochondrial Ca(2+) mobilization is a key element in olfactory signaling. Nat Neurosci (2012) 0.97
Mice lacking NKCC1 have normal olfactory sensitivity. Physiol Behav (2007) 0.94
Requirement of calcium-activated chloride channels in the activation of mouse vomeronasal neurons. Nat Commun (2011) 0.93
Signaling by olfactory receptor neurons near threshold. Proc Natl Acad Sci U S A (2010) 0.92
Channel properties of the splicing isoforms of the olfactory calcium-activated chloride channel Anoctamin 2. J Gen Physiol (2013) 0.91
Immunocytochemical characterization of two types of microvillar cells in rodent olfactory epithelium. Histochem Cell Biol (2005) 0.90
The effect of external sodium concentration on sodium-calcium exchange in frog olfactory receptor cells. J Physiol (2007) 0.89
Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons. PLoS One (2013) 0.88
Deep sequencing of the murine olfactory receptor neuron transcriptome. PLoS One (2015) 0.87
Anoctamin 1 mediates thermal pain as a heat sensor. Curr Neuropharmacol (2013) 0.86
Ion channel diversity, channel expression and function in the choroid plexuses. Cerebrospinal Fluid Res (2007) 0.86
Mechanism of olfactory masking in the sensory cilia. J Gen Physiol (2009) 0.86
Molecular evolution and functional divergence of the bestrophin protein family. BMC Evol Biol (2008) 0.86
Olfactory response termination involves Ca2+-ATPase in vertebrate olfactory receptor neuron cilia. J Gen Physiol (2010) 0.86
Conditional knockout of TMEM16A/anoctamin1 abolishes the calcium-activated chloride current in mouse vomeronasal sensory neurons. J Gen Physiol (2015) 0.85
Role of plasma membrane calcium ATPases in calcium clearance from olfactory sensory neurons. Chem Senses (2009) 0.83
Spatial distribution of calcium-gated chloride channels in olfactory cilia. PLoS One (2010) 0.82
Limits of calcium clearance by plasma membrane calcium ATPase in olfactory cilia. PLoS One (2009) 0.82
The Ca2+-activated Cl- channel TMEM16B regulates action potential firing and axonal targeting in olfactory sensory neurons. J Gen Physiol (2016) 0.81
Primary processes in sensory cells: current advances. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2008) 0.81
The membrane proteome of sensory cilia to the depth of olfactory receptors. Mol Cell Proteomics (2014) 0.80
Cellular and molecular Ca2+ microdomains in olfactory cilia support low signaling amplification of odor transduction. Eur J Neurosci (2010) 0.80
Identification of a Novel Gnao-Mediated Alternate Olfactory Signaling Pathway in Murine OSNs. Front Cell Neurosci (2016) 0.79
Cyclic-nucleotide-gated cation current and Ca2+-activated Cl current elicited by odorant in vertebrate olfactory receptor neurons. Proc Natl Acad Sci U S A (2016) 0.78
Analyzing and Modeling the Kinetics of Amyloid Beta Pores Associated with Alzheimer's Disease Pathology. PLoS One (2015) 0.78
Intracellular chloride concentration of the mouse vomeronasal neuron. BMC Neurosci (2015) 0.77
Super-resolution imaging of ciliary microdomains in isolated olfactory sensory neurons using a custom two-color stimulated emission depletion microscope. J Biomed Opt (2016) 0.77
The sweet smell of success: Conclusive evidence that cyclic AMP hydrolysis does not trigger fast adaptation in olfactory receptor cells. J Gen Physiol (2006) 0.77
Mechanisms of chloride uptake in frog olfactory receptor neurons. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2011) 0.77
Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex. PLoS One (2015) 0.76
Pulse stimulation with odors or IBMX/forskolin potentiates responses in isolated olfactory neurons. Chem Senses (2005) 0.76
Mechanisms of regulation of olfactory transduction and adaptation in the olfactory cilium. PLoS One (2014) 0.76
The long tale of the calcium activated Cl(-) channels in olfactory transduction. Channels (Austin) (2017) 0.75
Elevated Cytosolic Cl- Concentrations in Dendritic Knobs of Mouse Vomeronasal Sensory Neurons. Chem Senses (2016) 0.75
2,4,6-trichloroanisole is a potent suppressor of olfactory signal transduction. Proc Natl Acad Sci U S A (2013) 0.75
Simultaneous Loss of NCKX4 and CNG Channel Desensitization Impairs Olfactory Sensitivity. J Neurosci (2017) 0.75
In vivo determination of mouse olfactory mucus cation concentrations in normal and inflammatory states. PLoS One (2012) 0.75
Tracking of unfamiliar odors is facilitated by signal amplification through anoctamin 2 chloride channels in mouse olfactory receptor neurons. Physiol Rep (2017) 0.75
The dependence of calcium efflux from cardiac muscle on temperature and external ion composition. J Physiol (1968) 8.13
Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate. Science (1992) 6.72
Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release. Neuron (1998) 5.96
PDZ domains and the organization of supramolecular complexes. Annu Rev Neurosci (2001) 5.92
Cyclic nucleotide-gated ion channels. Physiol Rev (2002) 5.71
Sodium/calcium exchange: its physiological implications. Physiol Rev (1999) 5.42
Calcium influx and transmitter release in a fast CNS synapse. Nature (1996) 4.39
Single cyclic GMP-activated channel activity in excised patches of rod outer segment membrane. Nature (1986) 4.09
Linearized buffered Ca2+ diffusion in microdomains and its implications for calculation of [Ca2+] at the mouth of a calcium channel. J Neurosci (1997) 3.28
Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells. Nature (1993) 2.83
Transduction mechanisms in vertebrate olfactory receptor cells. Physiol Rev (1998) 2.66
Calcium-activated chloride conductance in frog olfactory cilia. J Neurosci (1991) 2.41
Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells. Nature (1993) 2.37
Extrusion of calcium from rod outer segments is driven by both sodium and potassium gradients. Nature (1989) 2.37
Direct modulation by Ca(2+)-calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons. Nature (1994) 2.35
Origin of the chloride current in olfactory transduction. Neuron (1993) 2.35
Profoundly different calcium permeation and blockage determine the specific function of distinct cyclic nucleotide-gated channels. Neuron (1995) 2.18
The cGMP-gated channel and related glutamic acid-rich proteins interact with peripherin-2 at the rim region of rod photoreceptor disc membranes. J Biol Chem (2001) 2.15
Neuronal Ca2+ -activated Cl- channels--homing in on an elusive channel species. Prog Neurobiol (2000) 2.11
Ca2(+)-dependent adaptive properties in the solitary olfactory receptor cell of the newt. Brain Res (1990) 2.07
Properties of cyclic nucleotide-gated channels mediating olfactory transduction. Activation, selectivity, and blockage. J Gen Physiol (1992) 1.95
Na+-dependent Ca2+ extrusion governs response recovery in frog olfactory receptor cells. J Gen Physiol (1998) 1.92
Hindered diffusion in excised membrane patches from retinal rod outer segments. Biophys J (1988) 1.79
Response properties of isolated mouse olfactory receptor cells. J Physiol (2001) 1.77
The biology of vision of Drosophila. Proc Natl Acad Sci U S A (1996) 1.69
Local routes revisited: the space and time dependence of the Ca2+ signal for phasic transmitter release at the rat calyx of Held. J Physiol (2003) 1.68
Ca2+ permeation in cyclic nucleotide-gated channels. EMBO J (1999) 1.54
Imaging odor-induced calcium transients in single olfactory cilia: specificity of activation and role in transduction. J Neurosci (1998) 1.50
Inactivation of calcium-activated chloride channels in smooth muscle by calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A (1997) 1.44
High-gain, low-noise amplification in olfactory transduction. Biophys J (1997) 1.43
The relation between stimulus and response in olfactory receptor cells of the tiger salamander. J Physiol (1993) 1.43
A depolarizing chloride current contributes to chemoelectrical transduction in olfactory sensory neurons in situ. J Neurosci (1998) 1.38
Noise analysis of ion channels in non-space-clamped cables: estimates of channel parameters in olfactory cilia. Biophys J (1997) 1.38
Divalent cations block the cyclic nucleotide-gated channel of olfactory receptor neurons. J Neurophysiol (1993) 1.35
Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors. Nature (1999) 1.32
Facilitation of calmodulin-mediated odor adaptation by cAMP-gated channel subunits. Science (2001) 1.30
Controversial issues in vertebrate olfactory transduction. Annu Rev Physiol (1999) 1.28
Predicted profiles of ion concentrations in olfactory cilia in the steady state. Biophys J (2001) 1.24
Both external and internal calcium reduce the sensitivity of the olfactory cyclic-nucleotide-gated channel to CAMP. J Neurophysiol (1999) 1.18
Odor-induced currents in Xenopus olfactory receptor cells measured with perforated-patch recording. J Neurophysiol (1995) 1.13
Characterization of calcium-activated chloride channels in patches excised from the dendritic knob of mammalian olfactory receptor neurons. J Membr Biol (1998) 1.11
Ca(2+)-dependent Cl(-) channels in mouse and rabbit aortic smooth muscle cells: regulation by intracellular Ca(2+) and NO. Am J Physiol (1999) 1.11
The organization of INAD-signaling complexes by a multivalent PDZ domain protein in Drosophila photoreceptor cells ensures sensitivity and speed of signaling. Cell Calcium (1999) 1.10
Binding of the cGMP-gated channel to the Na/Ca-K exchanger in rod photoreceptors. J Biol Chem (2000) 1.09
A biologic function for an "orphan" messenger: D-myo-inositol 3,4,5,6-tetrakisphosphate selectively blocks epithelial calcium-activated chloride channels. Proc Natl Acad Sci U S A (1996) 1.05
Regulation of Ca2+-dependent Cl- conductance in a human colonic epithelial cell line (T84): cross-talk between Ins(3,4,5,6)P4 and protein phosphatases. J Physiol (1998) 1.04
Amplification of odor-induced Ca(2+) transients by store-operated Ca(2+) release and its role in olfactory signal transduction. J Neurophysiol (2000) 1.03
Ca(2+)-activated C1- channels in a human biliary cell line: regulation by Ca2+/calmodulin-dependent protein kinase. Am J Physiol (1996) 1.02
Simultaneous recording of receptor current and intraciliary Ca2+ concentration in salamander olfactory receptor cells. J Physiol (2001) 1.01
Cyclic GMP-activated channels of salamander retinal rods: spatial distribution and variation of responsiveness. J Physiol (1992) 0.99
Noninvasive measurement of chloride concentration in rat olfactory receptor cells with use of a fluorescent dye. Am J Physiol Cell Physiol (2001) 0.99
Ionic channel rundown in excised membrane patches. Biochim Biophys Acta (1996) 0.97
Spontaneous gating of olfactory cyclic-nucleotide-gated channels. J Membr Biol (2000) 0.95
Effects of injecting calcium-buffer solution on [Ca2+]i in voltage-clamped snail neurons. Biophys J (1996) 0.94
Cloning and characterization of SLP3: a novel member of the stomatin family expressed by olfactory receptor neurons. J Assoc Res Otolaryngol (2002) 0.94
The local Ca concentration profile in the vicinity of a Ca channel. Cell Biochem Biophys (2001) 0.93
The permeation of organic cations through cAMP-gated channels in mammalian olfactory receptor neurons. J Membr Biol (1995) 0.89
A possible role for caveolin as a signaling organizer in olfactory sensory membranes. J Biol Chem (2000) 0.89
Association of cyclic GMP-gated channels and Na(+)-Ca(2+)-K+ exchangers in bovine retinal rod outer segment plasma membranes. J Physiol (1992) 0.86
Binding of the retinal rod Na+/Ca2+-K+ exchanger to the cGMP-gated channel indicates local Ca(2+)-signaling in vertebrate photoreceptors. Ann N Y Acad Sci (2002) 0.84
The contribution of a Ca(2+)-activated Cl(-) conductance to amino-acid-induced inward current responses of ciliated olfactory neurons of the rainbow trout. J Exp Biol (2000) 0.83
Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN. Nature (2005) 5.96
Central projections of melanopsin-expressing retinal ganglion cells in the mouse. J Comp Neurol (2006) 4.64
Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision. Nature (2008) 4.55
The vitelliform macular dystrophy protein defines a new family of chloride channels. Proc Natl Acad Sci U S A (2002) 3.73
Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells. Vision Res (2007) 2.64
Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons. Neuron (2005) 2.38
Breaking the covalent bond--a pigment property that contributes to desensitization in cones. Neuron (2005) 2.36
The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors. J Biol Chem (2007) 2.31
Structure-function analysis of the bestrophin family of anion channels. J Biol Chem (2003) 2.30
Phototransduction in mouse rods and cones. Pflugers Arch (2007) 2.23
The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry. Nature (2002) 2.21
Intrinsically photosensitive retinal ganglion cells. Physiol Rev (2010) 2.09
Photon capture and signalling by melanopsin retinal ganglion cells. Nature (2008) 2.08
Subunit stoichiometry of the CNG channel of rod photoreceptors. Neuron (2002) 1.71
Chloride accumulation in mammalian olfactory sensory neurons. J Neurosci (2004) 1.66
How vision begins: an odyssey. Proc Natl Acad Sci U S A (2008) 1.59
Role of visual pigment properties in rod and cone phototransduction. Nature (2003) 1.54
Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin. Proc Natl Acad Sci U S A (2005) 1.54
Elementary response of olfactory receptor neurons to odorants. Science (2005) 1.49
Signaling properties of a short-wave cone visual pigment and its role in phototransduction. J Neurosci (2007) 1.49
The proteome of rat olfactory sensory cilia. Proteomics (2009) 1.43
Calmodulin permanently associates with rat olfactory CNG channels under native conditions. Nat Neurosci (2004) 1.40
Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1. J Neurosci (2005) 1.40
Molecular components of signal amplification in olfactory sensory cilia. Proc Natl Acad Sci U S A (2010) 1.39
Regulation of cyclic nucleotide-gated channels. Curr Opin Neurobiol (2005) 1.39
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proc Natl Acad Sci U S A (2013) 1.36
Non-image-forming ocular photoreception in vertebrates. Curr Opin Neurobiol (2005) 1.33
Quantal noise from human red cone pigment. Nat Neurosci (2008) 1.31
Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels. J Gen Physiol (2013) 1.30
A family of octopamine [corrected] receptors that specifically induce cyclic AMP production or Ca2+ release in Drosophila melanogaster. J Neurochem (2005) 1.30
Loss of CNGB1 protein leads to olfactory dysfunction and subciliary cyclic nucleotide-gated channel trapping. J Biol Chem (2006) 1.20
Parietal-eye phototransduction components and their potential evolutionary implications. Science (2006) 1.17
Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina. J Neurosci (2012) 1.17
Proteomic analysis of a membrane preparation from rat olfactory sensory cilia. Chem Senses (2007) 1.17
Activation of visual pigments by light and heat. Science (2011) 1.16
Selective heteromeric assembly of cyclic nucleotide-gated channels. Proc Natl Acad Sci U S A (2003) 1.13
Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches. J Gen Physiol (2006) 1.13
Molecular properties of rhodopsin and rod function. J Biol Chem (2006) 1.12
On and off retinal circuit assembly by divergent molecular mechanisms. Science (2013) 1.12
Olfactory marker protein modulates the cAMP kinetics of the odour-induced response in cilia of mouse olfactory receptor neurons. J Physiol (2007) 1.11
Modulation of chloride homeostasis by inflammatory mediators in dorsal root ganglion neurons. Mol Pain (2008) 1.11
Determining consequences of retinal membrane guanylyl cyclase (RetGC1) deficiency in human Leber congenital amaurosis en route to therapy: residual cone-photoreceptor vision correlates with biochemical properties of the mutants. Hum Mol Genet (2012) 1.10
Tracer coupling of intrinsically photosensitive retinal ganglion cells to amacrine cells in the mouse retina. J Comp Neurol (2010) 1.07
Rod sensitivity of neonatal mouse and rat. J Gen Physiol (2005) 1.03
Calmodulin contributes to gating control in olfactory calcium-activated chloride channels. J Gen Physiol (2006) 1.03
Differential maturation of chloride homeostasis in primary afferent neurons of the somatosensory system. Int J Dev Neurosci (2007) 1.02
[7-(Dialkylamino)coumarin-4-yl]methyl-Caged Compounds as Ultrafast and Effective Long-Wavelength Phototriggers of 8-Bromo-Substituted Cyclic Nucleotides. Chembiochem (2003) 1.01
Farnesylation of retinal transducin underlies its translocation during light adaptation. Neuron (2005) 1.01
Adaptation to steady light by intrinsically photosensitive retinal ganglion cells. Proc Natl Acad Sci U S A (2013) 0.96
Intrinsic light response of retinal horizontal cells of teleosts. Nature (2009) 0.95
Unitary response of mouse olfactory receptor neurons. Proc Natl Acad Sci U S A (2010) 0.95
Signaling by olfactory receptor neurons near threshold. Proc Natl Acad Sci U S A (2010) 0.92
A yellow fluorescent protein-based assay for high-throughput screening of glycine and GABAA receptor chloride channels. Neurosci Lett (2005) 0.91
Caged capsaicins: New tools for the examination of TRPV1 channels in somatosensory neurons. Chembiochem (2007) 0.90
Expression patterns of anoctamin 1 and anoctamin 2 chloride channels in the mammalian nose. Cell Tissue Res (2012) 0.90
Rod sensitivity during Xenopus development. J Gen Physiol (2002) 0.89
Bestrophin 2: an anion channel associated with neurogenesis in chemosensory systems. J Comp Neurol (2009) 0.87
In vivo gene delivery in the retina using polyethylenimine. Biotechniques (2007) 0.85
Calcium and phototransduction. Adv Exp Med Biol (2002) 0.85
Assembly of retinal rod or cone Na(+)/Ca(2+)-K(+) exchanger oligomers with cGMP-gated channel subunits as probed with heterologously expressed cDNAs. Biochemistry (2003) 0.85
Targeted expression of anoctamin calcium-activated chloride channels in rod photoreceptor terminals of the rodent retina. Invest Ophthalmol Vis Sci (2013) 0.83
Distinct binding properties distinguish LQ-type calmodulin-binding domains in cyclic nucleotide-gated channels. Biochemistry (2011) 0.83
Light responses of primate and other mammalian cones. Proc Natl Acad Sci U S A (2014) 0.83
Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism. J Neurosci (2010) 0.81
Fluorescence spectroscopic quantification of the release of cyclic nucleotides from photocleavable [bis(carboxymethoxy)coumarin-4-yl]methyl esters inside cells. Angew Chem Int Ed Engl (2002) 0.81
Activation and desensitization of the olfactory cAMP-gated transduction channel: identification of functional modules. J Gen Physiol (2009) 0.80
Neuropeptide receptors provide a signalling pathway for trigeminal modulation of olfactory transduction. Eur J Neurosci (2012) 0.79
Photochemical nature of parietopsin. Biochemistry (2012) 0.77
PHR1, a PH domain-containing protein expressed in primary sensory neurons. Mol Cell Biol (2004) 0.76
Introducing Marie E. Burns, the 2009 Recipient of the Cogan Award. Invest Ophthalmol Vis Sci (2010) 0.75
Introducing Vadim Y. Arshavsky and Theodore G. Wensel, the 2013 recipients of the proctor medal. Invest Ophthalmol Vis Sci (2013) 0.75