Published in Cancer Gene Ther on September 01, 2003
Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling. PLoS One (2010) 1.40
HECT E3s and human disease. BMC Biochem (2007) 1.19
Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc. Proc Natl Acad Sci U S A (2013) 0.99
Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53. J Virol (2005) 0.91
Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum Mol Genet (2008) 2.33
Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth. Nat Med (2003) 2.03
Effect of deoxyribozymes targeting c-Jun on solid tumor growth and angiogenesis in rodents. J Natl Cancer Inst (2004) 2.00
Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia. Biol Psychiatry (2010) 1.58
MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood. PLoS One (2010) 1.49
Identifying miRNAs, targets and functions. Brief Bioinform (2012) 1.35
MicroRNA dysregulation in schizophrenia. Neurobiol Dis (2011) 1.28
Molecular mechanisms and treatment of radiation-induced lung fibrosis. Curr Drug Targets (2013) 1.27
Down-regulation of miR-17 family expression in response to retinoic acid induced neuronal differentiation. Cell Signal (2009) 1.26
A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia. Brain Behav Immun (2012) 1.17
Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites. Nucleic Acids Res (2003) 1.14
Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc finger transcription factor EGR-1. Nucleic Acids Res (2004) 1.11
Long-term survival and concomitant gene expression of ribozyme-transduced CD4+ T-lymphocytes in HIV-infected patients. J Gene Med (2005) 1.11
Expressing functional siRNAs in mammalian cells using convergent transcription. BMC Biotechnol (2003) 1.11
Post-transcriptional trafficking and regulation of neuronal gene expression. Mol Neurobiol (2011) 1.09
Transcriptome sequencing revealed significant alteration of cortical promoter usage and splicing in schizophrenia. PLoS One (2012) 1.07
Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies. Am J Pathol (2007) 1.01
DNAzymes targeted to EBV-encoded latent membrane protein-1 induce apoptosis and enhance radiosensitivity in nasopharyngeal carcinoma. Cancer Lett (2008) 1.01
Substituted 9-aminoacridine-4-carboxamides tethered to platinum(II)diamine complexes: chemistry, cytotoxicity and DNA sequence selectivity. J Inorg Biochem (2010) 1.01
Cellular uptake, distribution, and stability of 10-23 deoxyribozymes. Antisense Nucleic Acid Drug Dev (2002) 0.99
Gene set enrichment analysis of RNA-Seq data: integrating differential expression and splicing. BMC Bioinformatics (2013) 0.97
A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration. BMC Genomics (2012) 0.93
Protein detection methods in proteomics research. Biosci Rep (2005) 0.93
Effect of EBV LMP1 targeted DNAzymes on cell proliferation and apoptosis. Cancer Gene Ther (2005) 0.91
Inhibition of highly pathogenic avian H5N1 influenza virus replication by RNA oligonucleotides targeting NS1 gene. Biochem Biophys Res Commun (2007) 0.91
Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells. J Psychiatr Res (2012) 0.90
Regulation of gene expression by microRNA in HCV infection and HCV-mediated hepatocellular carcinoma. Virol J (2014) 0.89
Suppression of retinol-binding protein 4 with RNA oligonucleotide prevents high-fat diet-induced metabolic syndrome and non-alcoholic fatty liver disease in mice. Biochim Biophys Acta (2011) 0.87
Context-specific microRNA function in developmental complexity. J Mol Cell Biol (2013) 0.87
Mast cell-induced lung injury in mice infected with H5N1 influenza virus. J Virol (2012) 0.86
Gene-microRNA interactions associated with antipsychotic mechanisms and the metabolic side effects of olanzapine. Psychopharmacology (Berl) (2013) 0.86
A therapeutic approach to nasopharyngeal carcinomas by DNAzymes targeting EBV LMP-1 gene. Molecules (2010) 0.85
Comparative proteomic analysis using samples obtained with laser microdissection and saturation dye labelling. Proteomics (2005) 0.84
Maturation of the human dorsolateral prefrontal cortex coincides with a dynamic shift in microRNA expression. Schizophr Bull (2013) 0.84
Alternative mRNA fates identified in microRNA-associated transcriptome analysis. BMC Genomics (2012) 0.84
Selective labelling of cell-surface proteins using CyDye DIGE Fluor minimal dyes. J Vis Exp (2008) 0.81
Inhibition of highly pathogenic avian H5N1 influenza virus propagation by RNA oligonucleotides targeting the PB2 gene in combination with celecoxib. J Gene Med (2011) 0.81
Prophylactic, therapeutic and immune enhancement effect of liposome-encapsulated PolyICLC on highly pathogenic H5N1 influenza infection. J Gene Med (2011) 0.81
Acute, multiple-dose dermal and genetic toxicity of Nu-3: a novel antimicrobial agent. J Biomed Biotechnol (2010) 0.80
Antimicrobial activity and mechanism of action of Nu-3, a protonated modified nucleotide. Ann Clin Microbiol Antimicrob (2011) 0.80
Broad-spectrum and virus-specific nucleic acid-based antivirals against influenza. Front Biosci (Schol Ed) (2010) 0.80
Expression of NPAS3 in the human cortex and evidence of its posttranscriptional regulation by miR-17 during development, with implications for schizophrenia. Schizophr Bull (2012) 0.78
RNA modulators of complex phenotypes in mammalian cells. PLoS One (2009) 0.78
DCE-MRI assessment of the effect of Epstein-Barr virus-encoded latent membrane protein-1 targeted DNAzyme on tumor vasculature in patients with nasopharyngeal carcinomas. BMC Cancer (2014) 0.77
MicroRNA-16 is down-regulated in mutated FLT3 expressing murine myeloid FDC-P1 cells and interacts with Pim-1. PLoS One (2012) 0.77
Optimal consistency in microRNA expression analysis using reference-gene-based normalization. Mol Biosyst (2015) 0.77
Design and interpretation of microRNA-reporter gene activity. Anal Biochem (2013) 0.77
A proteomics approach to the study of absorption, distribution, metabolism, excretion, and toxicity. J Biomol Tech (2004) 0.76
Recent patents in antiviral siRNAs. Recent Pat Antiinfect Drug Discov (2010) 0.75
Nucleic acid sequence analysis using DNAzymes. Methods Mol Biol (2004) 0.75
Target-site selection for the 10-23 DNAzyme. Methods Mol Biol (2004) 0.75
Discovering functional microRNA-mRNA regulatory modules in heterogeneous data. Adv Exp Med Biol (2013) 0.75
Homogeneous real-time detection and quantification of nucleic acid amplification using restriction enzyme digestion. Biochem Biophys Res Commun (2004) 0.75