Published in Am J Physiol Heart Circ Physiol on August 28, 2003
Retracted The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates microRNA-155 binding. J Biol Chem (2007) 2.60
Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells. Am J Physiol Cell Physiol (2012) 1.62
The involvement of nitric oxide in the cutaneous vasoconstrictor response to local cooling in humans. J Physiol (2006) 1.29
Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors. Am J Physiol Heart Circ Physiol (2008) 0.95
Attenuated noradrenergic sensitivity during local cooling in aged human skin. J Physiol (2005) 0.95
Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses. Pharmacogenet Genomics (2008) 0.94
Desensitization of vascular response in vivo: contribution of genetic variation in the [alpha]2B-adrenergic receptor subtype. J Hypertens (2010) 0.89
Angiotensin AT1 - α2C-Adrenoceptor Interaction Disturbs α2A-auto-Inhibition of Catecholamine Release in Hypertensive Rats. Front Neurol (2013) 0.87
Intracellular α(2C)-adrenoceptors: storage depot, stunted development or signaling domain? Biochim Biophys Acta (2011) 0.86
Regulation of vascular reactivity in scleroderma: new insights into Raynaud's phenomenon. Rheum Dis Clin North Am (2008) 0.82
Cyclic AMP-Rap1A signaling mediates cell surface translocation of microvascular smooth muscle α2C-adrenoceptors through the actin-binding protein filamin-2. Am J Physiol Cell Physiol (2013) 0.81
α2-Adrenoreceptor Constraint of Catecholamine Release and Blood Pressure Is Enhanced in Female Spontaneously Hypertensive Rats. Front Neurosci (2016) 0.79
GABAB receptors are expressed in human aortic smooth muscle cells and regulate the intracellular Ca(2+) concentration. Heart Vessels (2014) 0.78
[Primary and secondary Raynaud's phenomenon]. Z Rheumatol (2008) 0.77
Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise. Physiol Genomics (2015) 0.77
In silico modeling of human α2C-adrenoreceptor interaction with filamin-2. PLoS One (2014) 0.77
Effect of skin temperature on cutaneous vasodilator response to the β-adrenergic agonist isoproterenol. J Appl Physiol (1985) (2015) 0.77
Delocalization of Endogenous A-kinase Antagonizes Rap1-Rho-α2C-Adrenoceptor Signaling in Human Microvascular Smooth Muscle Cells. J Cytol Mol Biol (2014) 0.76
Raynaud's Phenomenon: A Brief Review of the Underlying Mechanisms. Front Pharmacol (2016) 0.75
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell (2009) 11.10
Dystrophin immunity in Duchenne's muscular dystrophy. N Engl J Med (2010) 4.28
Limb-girdle muscular dystrophy type 2D gene therapy restores alpha-sarcoglycan and associated proteins. Ann Neurol (2009) 3.69
Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat Med (2009) 3.25
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest (2012) 3.14
Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children. Stroke (2006) 2.54
Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration. Sci Transl Med (2011) 2.35
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Cancer Res (2006) 2.32
Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity. Nat Med (2007) 2.23
Follistatin gene delivery enhances muscle growth and strength in nonhuman primates. Sci Transl Med (2009) 2.21
Cold-induced cutaneous vasoconstriction is mediated by Rho kinase in vivo in human skin. Am J Physiol Heart Circ Physiol (2006) 2.08
Genetic fate of recombinant adeno-associated virus vector genomes in muscle. J Virol (2003) 2.07
Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction. Circ Res (2005) 2.04
Sustained alpha-sarcoglycan gene expression after gene transfer in limb-girdle muscular dystrophy, type 2D. Ann Neurol (2010) 2.02
Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes. Circ Res (2003) 1.99
A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophy. J Transl Med (2007) 1.86
Physiological properties of hypothalamic MCH neurons identified with selective expression of reporter gene after recombinant virus infection. Neuron (2004) 1.83
Pyrin critical to macrophage IL-1beta response to Francisella challenge. J Immunol (2009) 1.73
Characterization of adeno-associated virus genomes isolated from human tissues. J Virol (2005) 1.72
Role of promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene as a risk factor for cerebral venous thrombosis. Stroke (2007) 1.63
Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells. Am J Physiol Cell Physiol (2012) 1.62
Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice. Circ Res (2006) 1.58
Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal (2011) 1.57
Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material. Hum Gene Ther (2010) 1.51
Molecular characterization of adeno-associated viruses infecting children. J Virol (2005) 1.46
Generation of neutralizing activity against human immunodeficiency virus type 1 in serum by antibody gene transfer. J Virol (2002) 1.40
Novel adeno-associated virus vector vaccine restricts replication of simian immunodeficiency virus in macaques. J Virol (2005) 1.36
Persistent expression of FLAG-tagged micro dystrophin in nonhuman primates following intramuscular and vascular delivery. Mol Ther (2009) 1.35
Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness. Circ Res (2010) 1.30
Elevated levels of homocysteine compromise blood-brain barrier integrity in mice. Blood (2005) 1.28
Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells. J Biol Chem (2009) 1.27
Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension. Circulation (2012) 1.27
Rho kinase-mediated local cold-induced cutaneous vasoconstriction is augmented in aged human skin. Am J Physiol Heart Circ Physiol (2007) 1.26
High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis. FASEB J (2009) 1.25
The impact of cyclooxygenase-2 mediated inflammation on scarless fetal wound healing. Am J Pathol (2004) 1.20
Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice. Am J Physiol Cell Physiol (2008) 1.16
Gene therapy for muscular dystrophy: lessons learned and path forward. Neurosci Lett (2012) 1.16
Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction. Am J Physiol Heart Circ Physiol (2004) 1.15
Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo. Circulation (2011) 1.13
Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries. Circ Res (2010) 1.13
Monocyte derived microvesicles deliver a cell death message via encapsulated caspase-1. PLoS One (2009) 1.13
Rapid and efficient clearance of blood-borne virus by liver sinusoidal endothelium. PLoS Pathog (2011) 1.12
Infectious molecular clones of adeno-associated virus isolated directly from human tissues. J Virol (2008) 1.11
Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress. J Mol Cell Cardiol (2011) 1.11
Role of oxidative stress and nitric oxide in atherothrombosis. Front Biosci (2008) 1.10
Homologous recombination mediates functional recovery of dysferlin deficiency following AAV5 gene transfer. PLoS One (2012) 1.10
Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification. Biochem Biophys Res Commun (2011) 1.09
The vasculopathy of Raynaud's phenomenon and scleroderma. Rheum Dis Clin North Am (2003) 1.07
Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase. Circulation (2004) 1.07
Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II. Circulation (2005) 1.06
Determinants of human plasma glutathione peroxidase (GPx-3) expression. J Biol Chem (2004) 1.06
Hypertension caused by transgenic overexpression of Rac1. Antioxid Redox Signal (2007) 1.05
Both maximal expression of selenoproteins and selenoprotein deficiency can promote development of type 2 diabetes-like phenotype in mice. Antioxid Redox Signal (2011) 1.04
Quo vadis: whither homocysteine research? Cardiovasc Toxicol (2009) 1.04
Redox regulation in the extracellular environment. Circ J (2008) 1.02
Bone morphogenetic protein-2 decreases microRNA-30b and microRNA-30c to promote vascular smooth muscle cell calcification. J Am Heart Assoc (2012) 1.01
Increased oxidant activity mediates vascular dysfunction in vibration injury. J Pharmacol Exp Ther (2008) 1.01
Upregulation of osmo-mechanosensitive TRPV4 channel facilitates chronic hypoxia-induced myogenic tone and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2011) 1.01
Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(-/-) mice. Arterioscler Thromb Vasc Biol (2006) 1.00
Glucose-6-phosphate dehydrogenase-deficient mice have increased renal oxidative stress and increased albuminuria. FASEB J (2009) 0.98
Latency associated peptide has in vitro and in vivo immune effects independent of TGF-beta1. PLoS One (2008) 0.98
Acetylcholine causes endothelium-dependent contraction of mouse arteries. Am J Physiol Heart Circ Physiol (2005) 0.98
Activated monocytes induce smooth muscle cell death: role of macrophage colony-stimulating factor and cell contact. Circulation (2002) 0.98
Glutathione peroxidase-1 deficiency augments proinflammatory cytokine-induced redox signaling and human endothelial cell activation. J Biol Chem (2011) 0.97
Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells. Mol Cell Biochem (2009) 0.96
Pressure-induced maturation of endothelial cells on newborn mouse carotid arteries. Am J Physiol Heart Circ Physiol (2013) 0.95
Rational design and engineering of a modified adeno-associated virus (AAV1)-based vector system for enhanced retrograde gene delivery. Neurosurgery (2015) 0.94
Exercise, vascular stiffness, and tissue transglutaminase. J Am Heart Assoc (2014) 0.93
Cyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3. Am J Physiol Heart Circ Physiol (2010) 0.92
AAV-mediated overexpression of human α7 integrin leads to histological and functional improvement in dystrophic mice. Mol Ther (2013) 0.92
Distinct cAMP signaling pathways differentially regulate alpha2C-adrenoceptor expression: role in serum induction in human arteriolar smooth muscle cells. Am J Physiol Heart Circ Physiol (2004) 0.92
Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material. Hum Gene Ther (2014) 0.91
MAIL regulates human monocyte IL-6 production. J Immunol (2009) 0.91
Increasing glucose 6-phosphate dehydrogenase activity restores redox balance in vascular endothelial cells exposed to high glucose. PLoS One (2012) 0.91
Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress. Circ Res (2005) 0.89
Homocysteine and glutathione peroxidase-1. Antioxid Redox Signal (2007) 0.88
alpha 2B-adrenergic receptor activates MAPK via a pathway involving arachidonic acid metabolism, matrix metalloproteinases, and epidermal growth factor receptor transactivation. J Biol Chem (2002) 0.88
Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study. Am Heart J (2008) 0.88
Micro-dystrophin and follistatin co-delivery restores muscle function in aged DMD model. Hum Mol Genet (2013) 0.88
Glutathione peroxidase-1 modulates lipopolysaccharide-induced adhesion molecule expression in endothelial cells by altering CD14 expression. FASEB J (2010) 0.87
Endothelial dysfunction in the microcirculation of patients with obstructive sleep apnea. Am J Respir Crit Care Med (2010) 0.87
Nitric oxide regulates tissue transglutaminase localization and function in the vasculature. Amino Acids (2011) 0.86
High-resolution imaging of selenium in kidneys: a localized selenium pool associated with glutathione peroxidase 3. Antioxid Redox Signal (2011) 0.86
Intracellular α(2C)-adrenoceptors: storage depot, stunted development or signaling domain? Biochim Biophys Acta (2011) 0.86
The effect of phenotype on mechanical stretch-induced vascular smooth muscle cell apoptosis. J Vasc Res (2006) 0.85
Selective cleavage of nucleolar autoantigen B23 by granzyme B in differentiated vascular smooth muscle cells: insights into the association of specific autoantibodies with distinct disease phenotypes. Arthritis Rheum (2004) 0.84
Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance. Mol Nutr Food Res (2012) 0.83