|
1
|
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs.
|
Nature
|
2004
|
12.75
|
|
2
|
RNAi-mediated gene silencing in non-human primates.
|
Nature
|
2006
|
7.60
|
|
3
|
Analysis of gene function in somatic mammalian cells using small interfering RNAs.
|
Methods
|
2002
|
6.67
|
|
4
|
Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells.
|
J Biol Chem
|
2003
|
2.66
|
|
5
|
Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).
|
Antiviral Res
|
2007
|
2.06
|
|
6
|
Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts.
|
J Cell Biol
|
2007
|
1.27
|
|
7
|
The mitotic-spindle-associated protein astrin is essential for progression through mitosis.
|
J Cell Sci
|
2002
|
1.18
|
|
8
|
RNAi therapeutics: an update on delivery.
|
Curr Opin Mol Ther
|
2008
|
1.13
|
|
9
|
Effects of expressing lamin A mutant protein causing Emery-Dreifuss muscular dystrophy and familial partial lipodystrophy in HeLa cells.
|
Exp Cell Res
|
2003
|
0.87
|
|
10
|
Analysis of mammalian gene function using small interfering RNAs.
|
Nucleic Acids Res Suppl
|
2003
|
0.83
|