PubRank

Yansong Gu

Author PubWeight™ 27.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A 2003 9.14
2 Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res 2006 2.92
3 Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature 2003 2.92
4 Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer. Mol Cell Biol 2007 1.65
5 A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E. Cancer Res 2005 1.54
6 SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice. Breast Cancer Res 2007 1.30
7 Inhibition of SIRT1 deacetylase suppresses estrogen receptor signaling. Carcinogenesis 2009 1.11
8 Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice. Hepatology 2008 1.08
9 Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates. J Med Chem 2004 1.07
10 SIRT1 is dispensable for function of hematopoietic stem cells in adult mice. Blood 2012 1.00
11 Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods. J Med Chem 2006 0.91
12 DNA-PK suppresses a p53-independent apoptotic response to DNA damage. EMBO Rep 2008 0.85
13 A role for endogenous and radiation-induced DNA double-strand breaks in p53-dependent apoptosis during cortical neurogenesis. Radiat Res 2008 0.82
14 Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis. Gastroenterology 2009 0.80
15 Sirtuin 1 regulates SREBP-1c expression in a LXR-dependent manner in skeletal muscle. PLoS One 2012 0.77
16 Pulmonary toxicity and metabolic activation of dauricine in CD-1 mice. J Pharmacol Exp Ther 2009 0.76