The gammaherpesvirus 68 latency-associated nuclear antigen homolog is critical for the establishment of splenic latency.

PubWeight™: 1.70‹?› | Rank: Top 3%

🔗 View Article (PMC 228443)

Published in J Virol on October 01, 2003

Authors

Nathaniel J Moorman1, David O Willer, Samuel H Speck

Author Affiliations

1: Division of Microbiology and Immunology and The Center for Emerging Infectious Diseases, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia 30329, USA.

Articles citing this

Identification of viral genes essential for replication of murine gamma-herpesvirus 68 using signature-tagged mutagenesis. Proc Natl Acad Sci U S A (2005) 1.98

Latent herpesvirus infection arms NK cells. Blood (2010) 1.80

Viral latency and its regulation: lessons from the gamma-herpesviruses. Cell Host Microbe (2010) 1.70

Induction of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latency. J Virol (2005) 1.47

Murine gammaherpesvirus 68 open reading frame 31 is required for viral replication. J Virol (2004) 1.40

Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency. PLoS Pathog (2007) 1.39

Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection. J Virol (2006) 1.36

ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus. PLoS Pathog (2007) 1.33

A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology. J Exp Med (2008) 1.31

Gamma-herpesvirus latency requires T cell evasion during episome maintenance. PLoS Biol (2005) 1.20

Role of B-cell proliferation in the establishment of gammaherpesvirus latency. J Virol (2005) 1.15

Protein complexes associated with the Kaposi's sarcoma-associated herpesvirus-encoded LANA. Virology (2007) 1.14

The latency-associated nuclear antigen, a multifunctional protein central to Kaposi's sarcoma-associated herpesvirus latency. Future Microbiol (2011) 1.13

Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection. Elife (2015) 1.13

The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral production. J Virol (2010) 1.12

Identification of candidate gammaherpesvirus 68 genes required for virus replication by signature-tagged transposon mutagenesis. J Virol (2004) 1.12

CD80 and CD86 control antiviral CD8+ T-cell function and immune surveillance of murine gammaherpesvirus 68. J Virol (2006) 1.11

The MHV68 M2 protein drives IL-10 dependent B cell proliferation and differentiation. PLoS Pathog (2008) 1.11

Murine gammaherpesvirus 68 open reading frame 75c tegument protein induces the degradation of PML and is essential for production of infectious virus. J Virol (2008) 1.10

Murine gammaherpesvirus-68 inhibits antigen presentation by dendritic cells. PLoS One (2007) 1.10

Alternatively initiated gene 50/RTA transcripts expressed during murine and human gammaherpesvirus reactivation from latency. J Virol (2008) 1.05

Evidence for a multiprotein gamma-2 herpesvirus entry complex. J Virol (2007) 1.03

The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters. J Virol (2009) 1.01

Establishment of B-cell lines latently infected with reactivation-competent murine gammaherpesvirus 68 provides evidence for viral alteration of a DNA damage-signaling cascade. J Virol (2008) 1.01

Identification of spliced gammaherpesvirus 68 LANA and v-cyclin transcripts and analysis of their expression in vivo during latent infection. J Virol (2006) 1.01

Sumoylation of the Epstein-Barr virus BZLF1 protein inhibits its transcriptional activity and is regulated by the virus-encoded protein kinase. J Virol (2010) 0.99

ORF73-null murine gammaherpesvirus 68 reveals roles for mLANA and p53 in virus replication. J Virol (2007) 0.99

Global mRNA degradation during lytic gammaherpesvirus infection contributes to establishment of viral latency. PLoS Pathog (2011) 0.97

Establishment and maintenance of long-term murine gammaherpesvirus 68 latency in B cells in the absence of CD40. J Virol (2005) 0.96

A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins. PLoS Pathog (2013) 0.96

Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin. J Virol (2006) 0.96

Immune modulation during latent herpesvirus infection. Immunol Rev (2012) 0.96

Blimp-1-dependent plasma cell differentiation is required for efficient maintenance of murine gammaherpesvirus latency and antiviral antibody responses. J Virol (2009) 0.95

Use of a virus-encoded enzymatic marker reveals that a stable fraction of memory B cells expresses latency-associated nuclear antigen throughout chronic gammaherpesvirus infection. J Virol (2010) 0.92

Structure, function and physiological consequences of virally encoded chemokine seven transmembrane receptors. Br J Pharmacol (2008) 0.91

Identification of closely spaced but distinct transcription initiation sites for the murine gammaherpesvirus 68 latency-associated M2 gene. J Virol (2008) 0.90

Disruption of LANA in rhesus rhadinovirus generates a highly lytic recombinant virus. J Virol (2009) 0.90

Murine gammaherpesvirus 68 LANA is essential for virus reactivation from splenocytes but not long-term carriage of viral genome. J Virol (2010) 0.89

Unbiased mutagenesis of MHV68 LANA reveals a DNA-binding domain required for LANA function in vitro and in vivo. PLoS Pathog (2012) 0.89

Systematic mutagenesis of the murine gammaherpesvirus 68 M2 protein identifies domains important for chronic infection. J Virol (2008) 0.89

A single CD8+ T cell epitope sets the long-term latent load of a murid herpesvirus. PLoS Pathog (2008) 0.89

Induction of protective immunity against murine gammaherpesvirus 68 infection in the absence of viral latency. J Virol (2009) 0.89

An essential role for γ-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle. Proc Natl Acad Sci U S A (2013) 0.88

Identification of an Rta responsive promoter involved in driving gammaHV68 v-cyclin expression during virus replication. Virology (2007) 0.88

Phosphoproteomic analyses reveal signaling pathways that facilitate lytic gammaherpesvirus replication. PLoS Pathog (2013) 0.88

Murine gammaherpesvirus 68 LANA acts on terminal repeat DNA to mediate episome persistence. J Virol (2012) 0.87

Targeting mitotic chromosomes: a conserved mechanism to ensure viral genome persistence. Proc Biol Sci (2009) 0.86

The viral latency-associated nuclear antigen augments the B-cell response to antigen in vivo. J Virol (2010) 0.85

Simian virus 40 T/t antigens and lamin A/C small interfering RNA rescue the phenotype of an Epstein-Barr virus protein kinase (BGLF4) mutant. J Virol (2010) 0.84

Crystal structure of the gamma-2 herpesvirus LANA DNA binding domain identifies charged surface residues which impact viral latency. PLoS Pathog (2013) 0.83

Prospects of a novel vaccination strategy for human gamma-herpesviruses. Immunol Res (2010) 0.82

The ZIIR element of the Epstein-Barr virus BZLF1 promoter plays a central role in establishment and maintenance of viral latency. J Virol (2011) 0.82

Latent gammaherpesvirus 68 infection induces distinct transcriptional changes in different organs. J Virol (2013) 0.80

A gammaherpesviral internal repeat contributes to latency amplification. PLoS One (2007) 0.80

Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. PLoS One (2013) 0.80

Identification of alternative transcripts encoding the essential murine gammaherpesvirus lytic transactivator RTA. J Virol (2014) 0.80

Vaccination against a hit-and-run viral cancer. J Gen Virol (2010) 0.79

Modulation of B-cell tolerance by murine gammaherpesvirus 68 infection: requirement for Orf73 viral gene expression and follicular helper T cells. Immunology (2013) 0.79

Quantitative analysis of the bidirectional viral G-protein-coupled receptor and lytic latency-associated nuclear antigen promoter of Kaposi's sarcoma-associated herpesvirus. J Virol (2012) 0.78

Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. J Virol (2015) 0.76

Prevention of Tumor Formation by Latent Gammaherpesvirus Infection. PLoS One (2015) 0.75

Latency-Associated Nuclear Antigen E3 Ubiquitin Ligase Activity Impacts Gammaherpesvirus-Driven Germinal Center B Cell Proliferation. J Virol (2016) 0.75

A persistent virus vector confers superior anti-tumor immunity, compared with a non-persistent vector. Cancer Immunol Immunother (2010) 0.75

Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication. J Virol (2015) 0.75

Kaposi's Sarcoma Herpesvirus Genome Persistence. Front Microbiol (2016) 0.75

MHV68 Expressing KSHV LANA Reveals Both Functional Conservation and Divergence in LANA Homologs. J Virol (2017) 0.75

Cross-species conservation of episome maintenance provides a basis for in vivo investigation of Kaposi's sarcoma herpesvirus LANA. PLoS Pathog (2017) 0.75

Articles cited by this

A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. J Bacteriol (1988) 31.85

Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant. Gene (1995) 15.67

Complete sequence and genomic analysis of murine gammaherpesvirus 68. J Virol (1997) 7.71

A putative origin of replication of plasmids derived from Epstein-Barr virus is composed of two cis-acting components. Mol Cell Biol (1985) 6.44

Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen. Science (1999) 5.55

Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. J Gen Virol (1992) 5.42

The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen. J Virol (1997) 4.56

Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus, an alphaherpesvirus. J Virol (1999) 4.19

Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells. J Virol (1999) 4.12

Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome. J Virol (2000) 4.09

Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68. J Virol (1996) 4.02

Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus. J Clin Invest (1997) 3.71

Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages. J Immunol (2000) 3.51

Lung epithelial cells are a major site of murine gammaherpesvirus persistence. J Exp Med (1998) 3.45

Multiple EBNA1-binding sites are required to form an EBNA1-dependent enhancer and to activate a minimal replicative origin within oriP of Epstein-Barr virus. J Virol (1989) 3.15

Replication from oriP of Epstein-Barr virus requires human ORC and is inhibited by geminin. Cell (2001) 2.81

B cells regulate murine gammaherpesvirus 68 latency. J Virol (1999) 2.79

Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice. J Virol (1999) 2.56

Host and viral genetics of chronic infection: a mouse model of gamma-herpesvirus pathogenesis. Curr Opin Microbiol (1999) 2.49

Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus. EMBO J (2001) 2.46

DNA binding and modulation of gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus. J Virol (2001) 2.41

Murine gammaherpesvirus-induced splenomegaly: a critical role for CD4 T cells. J Gen Virol (1996) 2.37

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells. J Virol (2002) 2.32

Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomes. J Virol (2002) 2.28

Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein-Barr virus. Proc Natl Acad Sci U S A (2001) 2.24

Unraveling immunity to gamma-herpesviruses: a new model for understanding the role of immunity in chronic virus infection. Curr Opin Immunol (1999) 2.19

Characterization of tumor cell lines derived from murine gammaherpesvirus-68-infected mice. J Virol (1996) 2.19

Modulation of cellular and viral gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus. J Virol (2001) 2.19

Human herpesvirus 8 LANA interacts with proteins of the mSin3 corepressor complex and negatively regulates Epstein-Barr virus gene expression in dually infected PEL cells. J Virol (2000) 2.17

The primary sequence of rhesus monkey rhadinovirus isolate 26-95: sequence similarities to Kaposi's sarcoma-associated herpesvirus and rhesus monkey rhadinovirus isolate 17577. J Virol (2000) 2.15

EBNA-1: a protein pivotal to latent infection by Epstein-Barr virus. Rev Med Virol (2000) 2.12

The murine gammaherpesvirus 68 v-cyclin is a critical regulator of reactivation from latency. J Virol (2000) 2.01

The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen binds to specific sequences at the left end of the viral genome through its carboxy-terminus. Virology (2001) 1.92

Identification of the in vivo role of a viral bcl-2. J Exp Med (2002) 1.88

Analysis of murine gammaherpesvirus-68 transcription during lytic and latent infection. J Gen Virol (1999) 1.84

The minimal replicator of Epstein-Barr virus oriP. J Virol (2000) 1.75

The transcriptional activity of cAMP response element-binding protein-binding protein is modulated by the latency associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus. J Biol Chem (2001) 1.67

Interactions of murine gammaherpesvirus 68 with B and T cell lines. Virology (1993) 1.51

Requirement for CD40 ligand, CD4(+) T cells, and B cells in an infectious mononucleosis-like syndrome. J Virol (1999) 1.41

Kinetics of murine gammaherpesvirus 68 gene expression following infection of murine cells in culture and in mice. J Virol (2001) 1.39

Chromosome binding site of latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus is essential for persistent episome maintenance and is functionally replaced by histone H1. J Virol (2002) 1.37

The latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus activates two major essential Epstein-Barr virus latent promoters. J Virol (2001) 1.24

Latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus interacts with Tat and activates the long terminal repeat of human immunodeficiency virus type 1 in human cells. J Virol (2001) 1.21

Disruption of the gene encoding the gammaHV68 v-GPCR leads to decreased efficiency of reactivation from latency. Virology (2003) 1.08

The terminal repeats and latency-associated nuclear antigen of herpesvirus saimiri are essential for episomal persistence of the viral genome. J Gen Virol (2002) 1.04

The relative role of viral transformation and specific cytogenetic changes in the development of murine and human lymphomas. Haematol Blood Transfus (1981) 0.79

Articles by these authors

Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice. Am J Respir Crit Care Med (2007) 2.05

Long-term latent murine Gammaherpesvirus 68 infection is preferentially found within the surface immunoglobulin D-negative subset of splenic B cells in vivo. J Virol (2003) 2.01

Identification of the in vivo role of a viral bcl-2. J Exp Med (2002) 1.88

Pathogenesis and host control of gammaherpesviruses: lessons from the mouse. Annu Rev Immunol (2011) 1.84

Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation. J Virol (2002) 1.78

Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus. J Virol (2002) 1.74

Establishment and maintenance of gammaherpesvirus latency are independent of infective dose and route of infection. J Virol (2003) 1.67

Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells. J Immunol (2006) 1.58

Lung infection with gamma-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice. Am J Physiol Lung Cell Mol Physiol (2005) 1.56

Antibody to a lytic cycle viral protein decreases gammaherpesvirus latency in B-cell-deficient mice. J Virol (2002) 1.48

Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice. J Virol (2005) 1.46

Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection. Immunity (2002) 1.45

Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency. PLoS Pathog (2007) 1.39

Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replication. J Virol (2003) 1.39

Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitis. J Clin Invest (2002) 1.34

A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology. J Exp Med (2008) 1.31

Identification of infected B-cell populations by using a recombinant murine gammaherpesvirus 68 expressing a fluorescent protein. J Virol (2009) 1.31

A surface groove essential for viral Bcl-2 function during chronic infection in vivo. PLoS Pathog (2005) 1.30

Structural basis of chemokine sequestration by a herpesvirus decoy receptor. Cell (2002) 1.29

An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection. J Virol (2004) 1.28

Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpesvirus 68 reveals tissue-specific genetic requirements for latency. J Virol (2002) 1.25

Gammaherpesvirus-driven plasma cell differentiation regulates virus reactivation from latently infected B lymphocytes. PLoS Pathog (2009) 1.23

The murine gammaherpesvirus 68 M2 gene is required for efficient reactivation from latently infected B cells. J Virol (2005) 1.22

Effective vaccination against long-term gammaherpesvirus latency. J Virol (2003) 1.19

Role of B-cell proliferation in the establishment of gammaherpesvirus latency. J Virol (2005) 1.15

Signaling through Toll-like receptors induces murine gammaherpesvirus 68 reactivation in vivo. J Virol (2008) 1.14

Identification of candidate gammaherpesvirus 68 genes required for virus replication by signature-tagged transposon mutagenesis. J Virol (2004) 1.12

Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta. Virology (2003) 1.11

A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge. J Virol (2006) 1.11

The MHV68 M2 protein drives IL-10 dependent B cell proliferation and differentiation. PLoS Pathog (2008) 1.11

Disruption of the gene encoding the gammaHV68 v-GPCR leads to decreased efficiency of reactivation from latency. Virology (2003) 1.08

Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes. J Virol (2003) 1.08

Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses. PLoS Pathog (2006) 1.08

Methylation of the EBV genome and establishment of restricted latency in low-passage EBV-infected 293 epithelial cells. Virology (2002) 1.06

Tracking murine gammaherpesvirus 68 infection of germinal center B cells in vivo. PLoS One (2012) 1.05

Alternatively initiated gene 50/RTA transcripts expressed during murine and human gammaherpesvirus reactivation from latency. J Virol (2008) 1.05

Role for MyD88 signaling in murine gammaherpesvirus 68 latency. J Virol (2008) 1.05

Establishment of B-cell lines latently infected with reactivation-competent murine gammaherpesvirus 68 provides evidence for viral alteration of a DNA damage-signaling cascade. J Virol (2008) 1.01

Identification of spliced gammaherpesvirus 68 LANA and v-cyclin transcripts and analysis of their expression in vivo during latent infection. J Virol (2006) 1.01

Ex vivo stimulation of B cells latently infected with gammaherpesvirus 68 triggers reactivation from latency. J Virol (2005) 1.00

Characterization of murine gammaherpesvirus 68 v-cyclin interactions with cellular cdks. Virology (2005) 0.99

ORF73-null murine gammaherpesvirus 68 reveals roles for mLANA and p53 in virus replication. J Virol (2007) 0.99

NF-kappaB p50 plays distinct roles in the establishment and control of murine gammaherpesvirus 68 latency. J Virol (2009) 0.97

Establishment and maintenance of long-term murine gammaherpesvirus 68 latency in B cells in the absence of CD40. J Virol (2005) 0.96

Murine gammaherpesvirus 68 Rta-dependent activation of the gene 57 promoter. Virology (2005) 0.96

Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin. J Virol (2006) 0.96

An optimized CD8+ T-cell response controls productive and latent gammaherpesvirus infection. J Virol (2005) 0.96

Blimp-1-dependent plasma cell differentiation is required for efficient maintenance of murine gammaherpesvirus latency and antiviral antibody responses. J Virol (2009) 0.95

Expansion of effector memory TCR Vbeta4+ CD8+ T cells is associated with latent infection-mediated resistance to transplantation tolerance. J Immunol (2008) 0.95

In-fusion® cloning with vaccinia virus DNA polymerase. Methods Mol Biol (2012) 0.92

Murine gamma-herpesvirus immortalization of fetal liver-derived B cells requires both the viral cyclin D homolog and latency-associated nuclear antigen. PLoS Pathog (2011) 0.92

Identification of closely spaced but distinct transcription initiation sites for the murine gammaherpesvirus 68 latency-associated M2 gene. J Virol (2008) 0.90

Murine gammaherpesvirus 68 LANA is essential for virus reactivation from splenocytes but not long-term carriage of viral genome. J Virol (2010) 0.89

Unbiased mutagenesis of MHV68 LANA reveals a DNA-binding domain required for LANA function in vitro and in vivo. PLoS Pathog (2012) 0.89

Systematic mutagenesis of the murine gammaherpesvirus 68 M2 protein identifies domains important for chronic infection. J Virol (2008) 0.89

Inhibition of NF-kappaB signaling reduces virus load and gammaherpesvirus-induced pulmonary fibrosis. Am J Pathol (2010) 0.88

Identification of an Rta responsive promoter involved in driving gammaHV68 v-cyclin expression during virus replication. Virology (2007) 0.88

Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines. J Virol (2004) 0.87

Genomic sequencing and characterization of cynomolgus macaque cytomegalovirus. J Virol (2011) 0.86

Amplification of JNK signaling is necessary to complete the murine gammaherpesvirus 68 lytic replication cycle. J Virol (2012) 0.85

The de novo methyltransferases DNMT3a and DNMT3b target the murine gammaherpesvirus immediate-early gene 50 promoter during establishment of latency. J Virol (2010) 0.83

The M4 gene of gammaHV68 encodes a secreted glycoprotein and is required for the efficient establishment of splenic latency. Virology (2005) 0.83

EBV framed in Burkitt lymphoma. Nat Med (2002) 0.82

Deletion of Epstein-Barr virus regulatory sequences upstream of the EBNA gene promoter Wp1 is unfavorable for B-Cell immortalization. J Virol (2002) 0.81

Characterization of omental immune aggregates during establishment of a latent gammaherpesvirus infection. PLoS One (2012) 0.81

The absence of M1 leads to increased establishment of murine gammaherpesvirus 68 latency in IgD-negative B cells. J Virol (2013) 0.80

Identification of alternative transcripts encoding the essential murine gammaherpesvirus lytic transactivator RTA. J Virol (2014) 0.80

Genetic and phylogenetic characterization of the type II cyclobutane pyrimidine dimer photolyases encoded by Leporipoxviruses. Virology (2003) 0.80

Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. PLoS One (2013) 0.80

Isolation and characterization of cynomolgus macaque (Macaca fascicularis) cytomegalovirus (CyCMV). Virology (2011) 0.79

CD4 and CD8 T cells directly recognize murine gammaherpesvirus 68-immortalized cells and prevent tumor outgrowth. J Virol (2013) 0.79

Evaluation of cynomolgus macaque (Macaca fascicularis) endogenous retrovirus expression following simian immunodeficiency virus infection. PLoS One (2012) 0.77

Insights into chronic gamma-herpesvirus infections. Curr Opin Virol (2013) 0.77

Establishment of an immortal cynomolgus macaque fibroblast cell line for propagation of cynomolgus macaque cytomegalovirus (CyCMV). Arch Virol (2012) 0.77