PubRank

Christoph Gelhaus

Author PubWeight™ 30.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The natural anticancer compounds rocaglamides inhibit the Raf-MEK-ERK pathway by targeting prohibitin 1 and 2. Chem Biol 2012 1.82
2 In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides. Proc Natl Acad Sci U S A 2010 1.25
3 Human beta-defensin 2 and beta-defensin 3 chimeric peptides reveal the structural basis of the pathogen specificity of their parent molecules. Antimicrob Agents Chemother 2010 1.01
4 Caenopores are antimicrobial peptides in the nematode Caenorhabditis elegans instrumental in nutrition and immunity. Dev Comp Immunol 2009 1.00
5 Hydramacin-1, structure and antibacterial activity of a protein from the basal metazoan Hydra. J Biol Chem 2008 1.00
6 Aziridide-based inhibitors of cathepsin L: synthesis, inhibition activity, and docking studies. ChemMedChem 2006 0.95
7 Enrichment and analysis of secretory lysosomes from lymphocyte populations. BMC Immunol 2009 0.93
8 Developmentally induced changes of the proteome in the protozoan parasite Leishmania donovani. Proteomics 2003 0.93
9 The human antimicrobial protein psoriasin acts by permeabilization of bacterial membranes. Dev Comp Immunol 2009 0.93
10 The adapter protein Nck: role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes. Protein Sci 2010 0.93
11 2-D DIGE analysis of the proteome of extracts from peanut variants reveals striking differences in major allergen contents. Proteomics 2009 0.89
12 Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. J Med Chem 2010 0.89
13 Comparison of two genetically related Entamoeba histolytica cell lines derived from the same isolate with different pathogenic properties. Proteomics 2009 0.89
14 Effector granules in human T lymphocytes: proteomic evidence for two distinct species of cytotoxic effector vesicles. J Proteome Res 2011 0.88
15 Screening of protease inhibitors as antiplasmodial agents. Part I: Aziridines and epoxides. ChemMedChem 2007 0.88
16 Allicin and derivates are cysteine protease inhibitors with antiparasitic activity. Bioorg Med Chem Lett 2010 0.87
17 2-D DIGE analyses of enriched secretory lysosomes reveal heterogeneous profiles of functionally relevant proteins in leukemic and activated human NK cells. Proteomics 2008 0.87
18 Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors. J Med Chem 2009 0.86
19 Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes. Biochim Biophys Acta 2008 0.84
20 Synthesis and evaluation of non-peptidic cysteine protease inhibitors of P. falciparum derived from etacrynic acid. Molecules 2008 0.82
21 Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities. J Biol Chem 2012 0.82
22 Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells. Cell Commun Signal 2011 0.81
23 A novel horse alpha-defensin: gene transcription, recombinant expression and characterization of the structure and function. Biochem J 2007 0.81
24 Characterization of Phleum pratense pollen extracts by 2-D DIGE and allergen immunoreactivity. Proteomics 2010 0.80
25 Structure and function of a unique pore-forming protein from a pathogenic acanthamoeba. Nat Chem Biol 2012 0.80
26 Self-assembly of the isolated KCNQ2 subunit interaction domain. FEBS Lett 2007 0.79
27 Membrane pore formation by pentraxin proteins from Limulus, the American horseshoe crab. Biochem J 2008 0.78
28 An efficient fluorimetric method to measure the viability of intraerythrocytic Plasmodium falciparum. Biol Chem 2008 0.78
29 Detection and structural characterization of natural Ara h 7, the third peanut allergen of the 2S albumin family. J Proteome Res 2010 0.78
30 Blood system formation in the urochordate Ciona intestinalis requires the variable receptor vCRL1. Mol Biol Evol 2012 0.77
31 Membrane activity of a C-reactive protein. FEBS Lett 2009 0.77
32 Isolation of erythrocytes infected with viable early stages of Plasmodium falciparum by flow cytometry. Cytometry A 2012 0.76
33 On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. J Med Chem 2009 0.76
34 Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors. Bioorg Med Chem 2010 0.75
35 Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain. Eur J Med Chem 2010 0.75
36 Cationic detergents enable the separation of membrane proteins of Plasmodium falciparum-infected erythrocytes by 2D gel electrophoresis. Electrophoresis 2012 0.75
37 Development of antitrypanosomal and antiplasmodial nonpeptidic cysteine protease inhibitors based on N-protected-guanidino-furan and -pyrrole building blocks. ChemMedChem 2011 0.75
38 Cell-free synthesis and combinatorial selective 15N-labeling of the cytotoxic protein amoebapore A from Entamoeba histolytica. Protein Expr Purif 2009 0.75
39 Synthesis and pharmacological evaluation of fluorescent and photoactivatable analogues of antiplasmodial naphthylisoquinolines. J Med Chem 2007 0.75
40 Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors. Bioorg Med Chem 2009 0.75