Relationships between Lewy bodies and pale bodies in Parkinson's disease.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMID 1320323)

Published in Acta Neuropathol on January 01, 1992

Authors

G E Dale1, A Probst, P Luthert, J Martin, B H Anderton, P N Leigh

Author Affiliations

1: Department of Neurology, Institute of Psychiatry, London, UK.

Articles citing this

Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson's disease brain. Brain (2015) 2.32

Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies. Am J Pathol (2003) 1.67

Parkinson's disease and parkinsonism: neuropathology. Cold Spring Harb Perspect Med (2012) 1.41

Formation and development of Lewy pathology: a critical update. J Neurol (2009) 1.37

Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism. Cell Rep (2015) 1.10

LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease. Neuropathol Appl Neurobiol (2007) 1.08

Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease. J Neurosci (2014) 0.96

An early cytoplasmic change before Lewy body maturation: an ultrastructural study of the substantia nigra from an autopsy case of juvenile parkinsonism. Acta Neuropathol (1993) 0.94

Mitochondrial dysfunction in Parkinson's disease. Parkinsons Dis (2011) 0.93

Cortical and brainstem-type Lewy bodies are immunoreactive for the cyclin-dependent kinase 5. Am J Pathol (1995) 0.93

Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein. PLoS One (2013) 0.81

The topographic distribution of brain atrophy in cortical Lewy body disease: comparison with Alzheimer's disease. Acta Neuropathol (1995) 0.80

Articles cited by this

The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry (1988) 14.72

The brain-stem lesions in Parkinsonism. J Neurol Neurosurg Psychiatry (1953) 5.88

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants. Nature (1982) 4.93

Corticobasal degeneration. Brain (1989) 3.20

Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease. J Pathol (1988) 2.96

Lewy bodies of Parkinson's disease contain neurofilament antigens. Science (1983) 2.70

Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study. Acta Neuropathol (1988) 2.59

Ultrastructure of neurofibrillary tangles in Steele-Richardson-Olszewski syndrome. Arch Neurol (1973) 2.38

Ubiquitin-mediated pathways for intracellular proteolysis. Annu Rev Cell Biol (1987) 2.32

Alz-50, ubiquitin and tau immunoreactivity of neurofibrillary tangles, Pick bodies and Lewy bodies. J Neuropathol Exp Neurol (1988) 1.82

Alzheimer's paired helical filaments share epitopes with neurofilament side arms. EMBO J (1986) 1.81

The significance of the Lewy body in the diagnosis of idiopathic Parkinson's disease. Neuropathol Appl Neurobiol (1989) 1.79

Ubiquitin deposits in anterior horn cells in motor neurone disease. Neurosci Lett (1988) 1.77

A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin. Neurosci Lett (1988) 1.55

Reaction of Lewy bodies with antibodies to phosphorylated and non-phosphorylated neurofilaments. Neurosci Lett (1986) 1.53

Diffuse Lewy body disease: light and electron microscopic immunocytochemistry of senile plaques. Acta Neuropathol (1989) 1.52

An antigenic profile of Lewy bodies: immunocytochemical indication for protein phosphorylation and ubiquitination. J Neuropathol Exp Neurol (1989) 1.51

Cytoskeletal protein abnormalities in neurodegenerative diseases. Ann Neurol (1986) 1.35

Neuronal filaments in Alzheimer's, Pick's, and Parkinson's diseases. N Engl J Med (1985) 1.32

Alzheimer neurofibrillary tangles contain phosphorylated and hidden neurofilament epitopes. J Neurol Neurosurg Psychiatry (1986) 1.27

Ubiquitin-protein conjugates in Alzheimer's lesions. Neurosci Lett (1987) 1.21

Corticonigral degeneration with neuronal achromasia and basal neurofibrillary tangles. Acta Neuropathol (1990) 1.17

New aspects of the pathology of neurodegenerative disorders as revealed by ubiquitin antibodies. Acta Neuropathol (1989) 1.12

Selective presence of ubiquitin in intracellular inclusions. Am J Pathol (1989) 1.07

Alzheimer dementia and Pick's disease: neurofibrillary tangles and Pick bodies are associated with identical phosphorylated neurofilament epitopes. Acta Neuropathol (1987) 0.97

Colloid (hyaline) inclusion bodies in the central nervous system: their presence in the substantia nigra is diagnostic of Parkinson's disease. Hum Pathol (1988) 0.90

Gastrin responses in patients with adrenergic insufficiency. J Neurol Neurosurg Psychiatry (1988) 0.83

Articles by these authors

The autism-spectrum quotient (AQ): evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. J Autism Dev Disord (2001) 14.30

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell (1988) 10.29

Fast and fuel efficient? Optimal use of wind by flying albatrosses. Proc Biol Sci (2000) 5.73

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc Natl Acad Sci U S A (1997) 5.66

Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature (1989) 5.19

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants. Nature (1982) 4.93

Testing technical skill via an innovative "bench station" examination. Am J Surg (1997) 4.75

Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study. N Engl J Med (1992) 4.54

All classes of intermediate filaments share a common antigenic determinant defined by a monoclonal antibody. Cell (1981) 4.28

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Lancet (1996) 4.11

The Lewy-body variant of Alzheimer's disease. Clinical and pathological findings. Br J Psychiatry (1993) 3.95

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet (2000) 3.63

In vivo growth characteristics of leucine and methionine auxotrophic mutants of Mycobacterium bovis BCG generated by transposon mutagenesis. Infect Immun (1995) 3.56

A clinicopathological study of autism. Brain (1998) 3.49

Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease. Lancet (1992) 3.30

Development of the World Health Organization (WHO) community periodontal index of treatment needs (CPITN). Int Dent J (1982) 3.23

Primary gastrointestinal non-Hodgkin's lymphoma: I. Anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German Multicenter Study GIT NHL 01/92. J Clin Oncol (2001) 3.22

Energy saving in flight formation. Nature (2001) 3.17

Allelic exchange in Mycobacterium tuberculosis with long linear recombination substrates. J Bacteriol (1996) 2.98

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci Lett (1992) 2.85

Anti-tumor necrosis factor-alpha blockade improves insulin resistance in patients with rheumatoid arthritis. Clin Exp Rheumatol (2006) 2.80

What is the optimal age for starting lipid lowering treatment? A mathematical model. BMJ (2000) 2.65

Fronto-striatal cognitive deficits at different stages of Parkinson's disease. Brain (1992) 2.64

Large-scale taxonomic profiling of eukaryotic model organisms: a comparison of orthologous proteins encoded by the human, fly, nematode, and yeast genomes. Genome Res (1998) 2.60

Seasonality and the requirements for perpetuation and eradication of viruses in populations. Am J Epidemiol (1979) 2.58

Localization of ATP Sulfurylase and O-Acetylserine(thiol)lyase in Spinach Leaves. Plant Physiol (1990) 2.55

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain. J Neurosci (2000) 2.49

An encyclopedia of mouse genes. Nat Genet (1999) 2.48

Protein folding in the central cavity of the GroEL-GroES chaperonin complex. Nature (1996) 2.46

Treating chronic pain. Am Fam Physician (1997) 2.40

Neuron loss in APP transgenic mice. Nature (1998) 2.38

Protein folding in the cell: the role of molecular chaperones Hsp70 and Hsp60. Annu Rev Biophys Biomol Struct (1992) 2.31

The management of acute bronchiolitis. Thoracic Society of Australia and New Zealand. J Paediatr Child Health (1993) 2.30

Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol Dis (2004) 2.29

Flail arm syndrome: a distinctive variant of amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry (1998) 2.28

Topical or oral ibuprofen for chronic knee pain in older people. The TOIB study. Health Technol Assess (2008) 2.24

Retroviral diversity and distribution in vertebrates. J Virol (1998) 2.22

Chaperonin-mediated protein folding: GroES binds to one end of the GroEL cylinder, which accommodates the protein substrate within its central cavity. EMBO J (1992) 2.20

British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE. Thorax (2013) 2.17

An estimate of amyotrophic lateral sclerosis heritability using twin data. J Neurol Neurosurg Psychiatry (2010) 2.14

Routine quantitative analysis of brain and cerebrospinal fluid spaces with MR imaging. J Magn Reson Imaging (1992) 2.11

Association of microglia with amyloid plaques in brains of APP23 transgenic mice. Am J Pathol (1999) 2.10

Late complications after ligation and bypass for popliteal aneurysm. Br J Surg (2004) 2.07

Neuropathology in mice expressing human alpha-synuclein. J Neurosci (2000) 2.06

Anxiety among hospitalized latency-age children. J Dev Behav Pediatr (1990) 2.06

Validation of an objective structured assessment of technical skill for surgical residents. Acad Med (1996) 2.06

Three point mutations in the CFTR gene in French cystic fibrosis patients: identification by denaturing gradient gel electrophoresis. Hum Genet (1990) 2.05

Thyroid function tests: often justified in the acutely ill. Ann Clin Biochem (2000) 2.03

Malaria. Nurs Stand (2002) 2.02

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors. Cell (1996) 1.99

Alzheimer's disease: immunoreactivity of neurofibrillary tangles with anti-neurofilament and anti-paired helical filament antibodies. Brain Res (1984) 1.98

Diffusion tensor MRI assesses corticospinal tract damage in ALS. Neurology (1999) 1.98

Monoclonal antibodies to mammalian neurofilaments. Biosci Rep (1981) 1.96

Rethinking traditional thoughts. J Emerg Nurs (1991) 1.94

Neutrophil alkaline phosphatase in AIDS. Acta Haematol (1988) 1.94

The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis. Ann Rheum Dis (2008) 1.92

Abnormal temporal dynamics of visual attention in spatial neglect patients. Nature (1997) 1.92

Behavior and neurocognitive performance in children aged 5-10 years who snore compared to controls. J Clin Exp Neuropsychol (2000) 1.88

Dysregulated expression of androgen-responsive and nonresponsive genes in the androgen-independent prostate cancer xenograft model CWR22-R1. Cancer Res (2000) 1.87

Alpha-synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects. Neuropathol Appl Neurobiol (2006) 1.87

Accuracy of clinical diagnosis of Alzheimer's disease. BMJ (1990) 1.84

Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia. Neurosci Lett (1992) 1.82

Restrictions on smoking at home and urinary cotinine levels among children with asthma. Am J Prev Med (2000) 1.81

Alzheimer's paired helical filaments share epitopes with neurofilament side arms. EMBO J (1986) 1.81

Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia (2000) 1.80

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr Biol (1994) 1.80

Prognostic modelling of therapeutic interventions in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord (2002) 1.80

Efficacy of acupuncture in asthma: systematic review and meta-analysis of published data from 11 randomised controlled trials. Eur Respir J (2002) 1.79

Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. EMBO J (1995) 1.77

Prevalence of childhood sexual abuse experiences in a community sample of women. J Am Acad Child Adolesc Psychiatry (1993) 1.77

Ubiquitin deposits in anterior horn cells in motor neurone disease. Neurosci Lett (1988) 1.77

Increasing levels of estradiol are deleterious to embryonic implantation because they directly affect the embryo. Fertil Steril (2001) 1.76

New VAPB deletion variant and exclusion of VAPB mutations in familial ALS. Neurology (2008) 1.76

Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function. Mol Cell Biol (2001) 1.75

Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity. Brain (1991) 1.74

Cu/Zn superoxide dismutase gene mutations in amyotrophic lateral sclerosis: correlation between genotype and clinical features. J Neurol Neurosurg Psychiatry (1996) 1.74

The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype. Hum Mol Genet (2009) 1.73

Creatine monohydrate increases strength in patients with neuromuscular disease. Neurology (1999) 1.73

Natural history and clinical features of the flail arm and flail leg ALS variants. Neurology (2009) 1.71

The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types. Br J Cancer (2007) 1.70

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun (2011) 1.70

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry. J Neurochem (1998) 1.69

Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha. Proc Natl Acad Sci U S A (1998) 1.68

Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1. Nature (1999) 1.68

Volumetric analysis reveals corticospinal tract degeneration and extramotor involvement in ALS. Neurology (2001) 1.68

Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol (2013) 1.65

Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta. J Neurochem (2000) 1.65

Molecular recognition of acute myeloid leukemia using aptamers. Leukemia (2009) 1.63

A monoclonal antibody against neurofilament protein specifically labels a subpopulation of rat sensory neurones. J Comp Neurol (1984) 1.63

Respiratory aspects of neurological disease. J Neurol Neurosurg Psychiatry (1999) 1.61

Human angiotensin I-converting enzyme gene and endurance performance. J Appl Physiol (1985) (1999) 1.61

Necrotizing lymphadenitis. A study of 30 cases. Am J Surg Pathol (1983) 1.60

Neuritic plaques in senile dementia of Alzheimer type: a Golgi analysis in the hippocampal region. Brain Res (1983) 1.60

Correlation between functional and structural assessments of the optic nerve and retina in multiple sclerosis patients. Neurophysiol Clin (2010) 1.59

Effectiveness of the Ultraflex Diamond stent for the palliation of malignant biliary obstruction. Endoscopy (2002) 1.58

UK Back pain Exercise And Manipulation (UK BEAM) trial--national randomised trial of physical treatments for back pain in primary care: objectives, design and interventions [ISRCTN32683578]. BMC Health Serv Res (2003) 1.57

[The health of 16-to-19-year-old adolescents from the Canton of Vaud: their perceptions, practices and desires. Methods and initial results of a study]. Schweiz Rundsch Med Prax (1983) 1.56