Published in J Auton Pharmacol on June 01, 1992
A Gut Feeling about GABA: Focus on GABA(B) Receptors. Front Pharmacol (2010) 0.89
Peripheral GABAB agonists stimulate gastric acid secretion in mice. Br J Pharmacol (2004) 0.83
Vagal neurotransmission to the ferret lower oesophageal sphincter: inhibition via GABA(B) receptors. Br J Pharmacol (2000) 0.78
Effect of sildenafil on neuropathic pain and hemodynamics in rats. Yonsei Med J (2009) 0.76
The beta3-adrenoceptor agonist SR58611A ameliorates experimental colitis in rats. Neurogastroenterol Motil (2008) 1.44
Synthesis and evaluation of antihypertensive activity of 1,8-naphthyridine derivatives. Part X. Eur J Med Chem (2001) 1.39
Presence of a non-adrenergic inhibitory system in the human colon. Gut (1968) 1.35
Review article: molecular, pathological and therapeutic features of human enteric neuropathies. Aliment Pharmacol Ther (2008) 1.24
Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients. Ann Oncol (2001) 1.12
Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib. Br J Cancer (2008) 1.10
Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5,6-dihydrouracil after conventional and reduced test dose in cancer patients. Clin Cancer Res (2000) 1.09
Dose-finding study and pharmacokinetics of epirubicin and paclitaxel over 3 hours: a regimen with high activity and low cardiotoxicity in advanced breast cancer. J Clin Oncol (1997) 1.07
Proceedings: Prostaglandins in human colonic carcinoma. Gut (1975) 1.00
Periodontal tissue disposition of azithromycin in patients affected by chronic inflammatory periodontal diseases. J Periodontol (1999) 1.00
Gemcitabine plus epirubicin plus taxol (GET) in advanced breast cancer: a phase II study. Breast Cancer Res Treat (2001) 0.99
Cytotoxic activity of polyacetylenes and polyenes isolated from roots of Echinacea pallida. Br J Pharmacol (2008) 0.99
Gemcitabine, epirubicin and paclitaxel: pharmacokinetic and pharmacodynamic interactions in advanced breast cancer. Ann Oncol (2002) 0.99
Characterization of a novel mechanism accounting for the adverse cholinergic effects of the anticancer drug irinotecan. Br J Pharmacol (2001) 0.98
Suramin inhibits bFGF-induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane. Br J Cancer (1993) 0.97
Renal hemodynamic response to maximal vasodilating stimulus in healthy older subjects. Kidney Int (2001) 0.97
Cyclophosphamide-methotrexate 'metronomic' chemotherapy for the palliative treatment of metastatic breast cancer. A comparative pharmacoeconomic evaluation. Ann Oncol (2005) 0.97
In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients. Br J Cancer (2006) 0.96
Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells. Br J Cancer (2005) 0.96
Cardiotoxicity of epirubicin/paclitaxel-containing regimens: role of cardiac risk factors. J Clin Oncol (1999) 0.96
Role of cyclooxygenases 1 and 2 in the modulation of neuromuscular functions in the distal colon of humans and mice. Gut (2005) 0.95
Periodontal tissue disposition of azithromycin. J Periodontol (1997) 0.95
Hematologic toxicity of immunosuppressive treatment. Transplant Proc (2004) 0.94
The actions of atropine, tropenziline and N-butyl hyoscine bromide on the isolated distal colon of the guinea-pig: a comparison of their activities and mechanisms of action. J Pharm Pharmacol (1969) 0.94
Prolonged fixed dose rate infusion of gemcitabine with autologous haemopoietic support in advanced pancreatic adenocarcinoma. Br J Cancer (2005) 0.94
Sequence effect of irinotecan and fluorouracil treatment on pharmacokinetics and toxicity in chemotherapy-naive metastatic colorectal cancer patients. J Clin Oncol (2001) 0.94
The effect of lipoproteins on endothelial nitric oxide synthase is modulated by lipoperoxides. Eur J Clin Invest (2003) 0.94
Experiments on the mechanism of action of caerulein at the level of the guinea-pig ileum and colon. Agents Actions (1970) 0.93
Drug distribution and pharmacokinetic/pharmacodynamic relationship of paclitaxel and gemcitabine in patients with non-small-cell lung cancer. Ann Oncol (2001) 0.93
Some structural changes on triazolyl-benzotriazoles and triazolyl-benzimidazolones as potential potassium channel activators. III. Farmaco (2001) 0.93
Might adriamycinol contribute to adriamycin-induced cardiotoxicity? Pharmacol Res Commun (1985) 0.93
Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer. Br J Cancer (2011) 0.92
A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients. Br J Cancer (2008) 0.92
Pharmacokinetic optimisation of treatment schedules for anthracyclines and paclitaxel in patients with cancer. Clin Pharmacokinet (1999) 0.92
Acid-independent gastroprotective effects of lansoprazole in experimental mucosal injury. Dig Dis Sci (1999) 0.92
(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells. Br J Pharmacol (2006) 0.92
In-vitro evidence of autocrine secretion of vascular endothelial growth factor by endothelial cells from human placental blood vessels. Mol Hum Reprod (2001) 0.92
Antagonism of atropine towards endogenous and exogenous acetylcholine before and after sympathetic system blockade in the isolated distal guinea-pig colon. Eur J Pharmacol (1968) 0.92
Histamine H(3) receptors mediate inhibition of noradrenaline release from intestinal sympathetic nerves. Br J Pharmacol (2000) 0.90
Pharmacological studies on the mechanisms underlying the inhibitory and excitatory effects of clonidine on gastric acid secretion. Eur J Pharmacol (1982) 0.90
Some observations on the intrinsic nervous mechanism in Hirschsprung's disease. Gut (1973) 0.89
Mechanisms of protection by pantoprazole against NSAID-induced gastric mucosal damage. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.89
Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report. Eur J Clin Pharmacol (2002) 0.89
Superoxide anion production by adriamycinol from cardiac sarcosomes and by mitochondrial NADH dehydrogenase. Anticancer Res (1987) 0.89
Effects of imidazoline derivatives on cholinergic motility in guinea-pig ileum: involvement of presynaptic alpha2-adrenoceptors or imidazoline receptors? Naunyn Schmiedebergs Arch Pharmacol (1998) 0.89
Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines. J Ethnopharmacol (2006) 0.88
Characterization of mechanisms underlying the effects of esomeprazole on the impairment of gastric ulcer healing with addition of NSAID treatment. Dig Liver Dis (2009) 0.87
Pharmacokinetics of azithromycin in serum, bronchial washings, alveolar macrophages and lung tissue following a single oral dose of extended or immediate release formulations of azithromycin. J Antimicrob Chemother (2008) 0.87
Carbon dioxide degassing by advective flow from Usu volcano, Japan. Science (2001) 0.87
Azidothymidine in combination with 5-fluorouracil in human colorectal cell lines: in vitro synergistic cytotoxicity and DNA-induced strand-breaks. Eur J Cancer (1996) 0.87
Gastric mucosal distribution and clinical efficacy of azithromycin in patients with Helicobacter pylori related gastritis. J Antimicrob Chemother (1998) 0.87
Plasma and tissue disposition of paclitaxel (taxol) after intraperitoneal administration in mice. Drug Metab Dispos (1995) 0.86
Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo. Cancer Chemother Pharmacol (1999) 0.86
The heparan sulfate suleparoide inhibits rat corneal angiogenesis and in vitro neovascularization. Exp Eye Res (1998) 0.86
Interaction between gemcitabine and topotecan in human non-small-cell lung cancer cells: effects on cell survival, cell cycle and pharmacogenetic profile. Br J Cancer (2005) 0.86
Effects of esomeprazole on glutathione levels and mitochondrial oxidative phosphorylation in the gastric mucosa of rats treated with indomethacin. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.85
Suramin in combination with 5-fluorouracil (5-FU) and leucovorin (LV) in metastatic colorectal cancer patients resistant to 5-FU+LV-based chemotherapy. Tumori (1999) 0.85
Macrolide antibiotics as antiinflammatory agents: roxithromycin in an unexpected role. Agents Actions (1993) 0.85
Constitutive expression of cyclooxygenase-2 in the neuromuscular compartment of normal human colon. Neurogastroenterol Motil (2006) 0.85
FK-506 delays corneal graft rejection in a model of corneal xenotransplantation. J Ocul Pharmacol Ther (1996) 0.85
Seriate histomorphometry of whole rat stomach: an accurate and reliable method for quantitative analysis of mucosal damage. Toxicol Appl Pharmacol (2001) 0.84
Phenylacetate inhibits protein isoprenylation and growth of the androgen-independent LNCaP prostate cancer cells transfected with the T24 Ha-ras oncogene. Mol Pharmacol (1996) 0.84
Anthracycline cardiotoxicity: in vivo and in vitro effects on biochemical parameters and heart ultrastructure of the rat. Oncology (1991) 0.84
Phenobarbital prophylaxis of post traumatic epilepsy. Ital J Neurol Sci (1980) 0.84
Effect of low molecular weight heparan sulphate on angiogenesis in the rat cornea after chemical cauterization. J Ocul Pharmacol (1994) 0.84
Effect of varying noise stress duration on rat adrenal gland: an ultrastructural study. Tissue Cell (1997) 0.84
High-dose therapy with autologous PBSC transplantation in the front-line treatment of Waldenstrom's macroglobulinemia. Bone Marrow Transplant (2008) 0.84
Long-term exposure to noise modifies rat adrenal cortex ultrastructure and corticosterone plasma levels. J Submicrosc Cytol Pathol (1999) 0.84
3'-Deamino-3'-(2-methoxy-4-morpholinyl)-doxorubicin (FCE 23762): a new anthracycline derivative with enhanced cytotoxicity and reduced cardiotoxicity. Eur J Cancer (1993) 0.83
Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells. Br J Cancer (2001) 0.83
Manumycin inhibits ras signal transduction pathway and induces apoptosis in COLO320-DM human colon tumour cells. Br J Cancer (2000) 0.83
Action of catecholamines on release of acetylcholine from human taenia coli. Eur J Pharmacol (1970) 0.83
High-dose thiotepa and melphalan with hemopoietic progenitor support following induction therapy with epirubicin-paclitaxel-containing regimens in metastatic breast cancer (MBC). Ann Oncol (2001) 0.83
CCK1 and CCK2 receptors regulate gastric pepsinogen secretion. Eur J Pharmacol (1999) 0.83
Ring-pattern dynamics in smectic-C* and smectic-C*A freely suspended liquid crystal films. Phys Rev Lett (2000) 0.82
Cholecystokinin CCK2 receptors mediate the peptide's inhibitory actions on the contractile activity of human distal colon via the nitric oxide pathway. Br J Pharmacol (2007) 0.82
Linezolid cerebrospinal fluid concentration in central nervous system infection. J Chemother (2007) 0.82
Central GABAA excitatory and GABAB inhibitory receptors regulate gastric acid secretion in rats. Eur J Pharmacol (1990) 0.82
In vitro antiangiogenic activity of selective somatostatin subtype-1 receptor agonists. Eur J Clin Invest (2007) 0.82
A1 and A2a receptors mediate inhibitory effects of adenosine on the motor activity of human colon. Neurogastroenterol Motil (2008) 0.82
Effects of gonadotropin-releasing hormone (GnRH) on gastric secretion and gastrin release in the dog. J Endocrinol Invest (1983) 0.82
In vitro studies on gemcitabine combinations with other antiblastics. Ann Oncol (2006) 0.82
QT prolongation in anaesthetized guinea-pigs: an experimental approach for preliminary screening of torsadogenicity of drugs and drug candidates. J Appl Toxicol (2004) 0.82
Functional evidence that [3H]acetylcholine and [3H]noradrenaline release from guinea pig ileal myenteric plexus and noradrenergic terminals is modulated by different presynaptic alpha-2 adrenoceptor subtypes. J Pharmacol Exp Ther (1993) 0.81
Role of peripheral GABAB receptors in the regulation of pepsinogen secretion in anaesthetized rats. Eur J Pharmacol (1995) 0.81
Evidence for two opposite effects of clonidine on gastric acid secretion in the dog. Naunyn Schmiedebergs Arch Pharmacol (1984) 0.81
Cardiac toxicity and antitumor activity of 4'-deoxy-4'-iodo-doxorubicinol. Cancer Chemother Pharmacol (1990) 0.81
An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma. Ther Drug Monit (1999) 0.81
H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways. Naunyn Schmiedebergs Arch Pharmacol (2001) 0.81
Teratogenesis and immunosuppressive treatment. Transplant Proc (2004) 0.81
Antisecretory and anti-ulcer effects of morphine in rats after gastric mucosal aggression. Eur J Pharmacol (1991) 0.80
High-dose consolidation chemotherapy with Idarubicin and alkylating agents following induction with gemcitabine-epirubicin-paclitaxel in metastatic breast cancer: a dose finding study. Bone Marrow Transplant (2003) 0.80