PubRank

C J Vlahos

Author PubWeight™ 41.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 1994 5.13
2 Increased protein kinase C activity and expression of Ca2+-sensitive isoforms in the failing human heart. Circulation 1999 3.35
3 Rac GTPase interacts specifically with phosphatidylinositol 3-kinase. Biochem J 1996 1.78
4 Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation. J Biol Chem 1995 1.57
5 Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. Mol Cell Biol 1995 1.42
6 Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils. J Biol Chem 1995 1.34
7 Role of PRL-3, a human muscle-specific tyrosine phosphatase, in angiotensin-II signaling. Biochem Biophys Res Commun 2001 1.33
8 Stable expression of a secretable deletion mutant of recombinant human thrombomodulin in mammalian cells. J Biol Chem 1990 1.30
9 Calmodulin activates phosphatidylinositol 3-kinase. J Biol Chem 1997 1.25
10 Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002. Biochem Biophys Res Commun 1994 1.19
11 Studies on the mechanism of phosphatidylinositol 3-kinase inhibition by wortmannin and related analogs. J Med Chem 1996 1.18
12 Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption. Am J Physiol 1999 1.13
13 The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs. Biochem Biophys Res Commun 1992 1.09
14 Phosphatidylinositol 3-kinase activation is required for insulin-stimulated sodium transport in A6 cells. Am J Physiol 1998 1.08
15 Protein kinase C-alpha and -epsilon modulate connexin-43 phosphorylation in human heart. J Mol Cell Cardiol 2001 1.07
16 LY-294002-inhibitable PI 3-kinase and regulation of baseline rates of Na(+) transport in A6 epithelia. Am J Physiol Cell Physiol 2000 1.04
17 Identification of the predominant glycosaminoglycan-attachment site in soluble recombinant human thrombomodulin: potential regulation of functionality by glycosyltransferase competition for serine474. Biochem J 1993 1.00
18 Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK alpha is the predominant isoform expressed in human heart. J Mol Cell Cardiol 2001 1.00
19 Inhibition of neutrophil oxidative burst and granule secretion by wortmannin: potential role of MAP kinase and renaturable kinases. J Cell Physiol 1997 1.00
20 Wortmannin and LY294002 inhibit the insulin-induced down-regulation of IRS-1 in 3T3-L1 adipocytes. Mol Cell Endocrinol 1995 0.90
21 Possible involvement of phosphatidylinositol 3-kinase in regulated exocytosis: studies in chromaffin cells with inhibitor LY294002. J Neurochem 1998 0.89
22 Platelet derived growth factor (PDGF), androgens and inflammation: possible etiologic factors in the development of prostatic hyperplasia. J Urol 1993 0.86
23 Synthesis and in vitro evaluation of new wortmannin esters: potent inhibitors of phosphatidylinositol 3-kinase. J Med Chem 1996 0.86
24 Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells. Biochem Biophys Res Commun 2001 0.86
25 Evidence for an essential arginine residue in the active site of Escherichia coli 2-keto-4-hydroxyglutarate aldolase. Modification with 1,2-cyclohexanedione. J Biol Chem 1985 0.84
26 Recombinant human thrombomodulin. Regulation of cofactor activity and anticoagulant function by a glycosaminoglycan side chain. Biochem J 1992 0.83
27 Functional properties of the recombinant kringle-2 domain of tissue plasminogen activator produced in Escherichia coli. J Biol Chem 1990 0.82
28 Inhibition of MG-63 cell proliferation and PDGF-stimulated cellular processes by inhibitors of phosphatidylinositol 3-kinase. J Cell Biochem 1997 0.82
29 Insulin and insulin-like growth factor-I receptor mediated differentiation of 3T3-F442A cells into adipocytes: effect of PI 3-kinase inhibition. Biochem Biophys Res Commun 1998 0.82
30 Amino acid sequence of the pyruvate and the glyoxylate active-site lysine peptide of Escherichia coli 2-keto-4-hydroxyglutarate aldolase. J Biol Chem 1986 0.80
31 LY295427, a novel hypocholesterolemic agent, enhances [3H]25-hydroxycholesterol binding to liver cytosolic proteins. J Lipid Res 1996 0.79
32 Characterization of a modified human tissue plasminogen activator comprising a kringle-2 and a protease domain. J Biol Chem 1990 0.79
33 Design and implementation of a particle concentration fluorescence method for the detection of HIV-1 protease inhibitors. Anal Biochem 1992 0.79
34 Effects of wortmannin analogs on bone in vitro and in vivo. J Pharmacol Exp Ther 1996 0.77
35 Signaling pathways mediated by the beta(2)-adrenergic receptor in the fibroblast: a novel role for PI 3-kinase. J Mol Cell Cardiol 2001 0.75
36 Purification of recombinant HIV-1 protease. Prep Biochem 1991 0.75
37 Effects of prolonged ethinyl estradiol treatment on calcium channel binding and in vivo calcium-mediated hemodynamic responses in ovariectomized rats. J Pharmacol Exp Ther 1997 0.75