PubRank

G W Bornkamm

Author PubWeight™ 186.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Covalently closed circular duplex DNA of Epstein-Barr virus in a human lymphoid cell line. J Mol Biol 1976 7.42
2 The transcriptional program of a human B cell line in response to Myc. Nucleic Acids Res 2001 4.08
3 Control of cell growth by c-Myc in the absence of cell division. Curr Biol 1999 3.90
4 Deletion of the nontransforming Epstein-Barr virus strain P3HR-1 causes fusion of the large internal repeat to the DSL region. J Virol 1982 3.16
5 Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene. J Virol 1991 3.03
6 Comparison of Epstein-Barr virus strains of different origin by analysis of the viral DNAs. J Virol 1980 3.00
7 Structure of Herpesvirus saimiri genomes: arrangement of heavy and light sequences in the M genome. J Virol 1976 2.87
8 Heterogeneity of Epstein-Barr virus. III. Comparison of a transforming and a nontransforming virus by partial denaturation mapping of their DNAs. J Virol 1978 2.78
9 The Epstein-Barr virus nuclear antigen 2 interacts with an EBNA2 responsive cis-element of the terminal protein 1 gene promoter. EMBO J 1993 2.74
10 Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression. Nucleic Acids Res 1986 2.71
11 Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless. EMBO J 1994 2.69
12 Cell cycle activation by c-myc in a burkitt lymphoma model cell line. Int J Cancer 2000 2.59
13 Tumor initiators and promoters in the induction of Epstein-Barr virus. Proc Natl Acad Sci U S A 1979 2.55
14 B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2. EMBO J 1995 2.51
15 A complete set of overlapping cosmid clones of M-ABA virus derived from nasopharyngeal carcinoma and its similarity to other Epstein-Barr virus isolates. Gene 1984 2.44
16 Repetitive sequences in complete and defective genomes of Herpesvirus saimiri. J Virol 1975 2.36
17 Structure of defective DNA molecules in Epstein-Barr virus preparations from P3HR-1 cells. J Virol 1984 2.23
18 Intracellular forms of Epstein-Barr virus DNA in human tumour cells in vivo. Nature 1976 2.10
19 A putative transforming gene of Jijoye virus differs from that of Epstein-Barr virus prototypes. Virology 1985 2.07
20 Attempts to detect virus-secific DNA in human tumors. I. Nucleic acid hybridizations with complementary RNA of human wart virus. Int J Cancer 1974 1.98
21 Burkitt lymphoma in the mouse. J Exp Med 2000 1.96
22 Episomal viral DNA in a Herpesvirus saimiri-transformed lymphoid cell line. J Virol 1977 1.93
23 Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene. Nucleic Acids Res 1985 1.91
24 RBP-L, a transcription factor related to RBP-Jkappa. Mol Cell Biol 1997 1.89
25 Two deletions in the Epstein-Barr virus genome of the Burkitt lymphoma nonproducer line Raji. Virology 1984 1.85
26 Two distant clusters of partially homologous small repeats of Epstein-Barr virus are transcribed upon induction of an abortive or lytic cycle of the virus. J Virol 1983 1.82
27 The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2. J Virol 1999 1.81
28 Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives. EMBO J 1985 1.76
29 Heterogeneity of Epstein-Barr virus originating from P3HR-1 cells. I. Studies on EBNA induction. Int J Cancer 1977 1.70
30 Identification of the coding region for a second Epstein-Barr virus nuclear antigen (EBNA 2) by transfection of cloned DNA fragments. EMBO J 1985 1.65
31 Target sequences for cis-acting regulation within the dual promoter of the human c-myc gene. Mol Cell Biol 1987 1.63
32 Biological and biochemical observations on isolates of EB virus from the malignant epithelial cells of two nasopharyngeal carcinomas. Int J Cancer 1979 1.62
33 Expression of Epstein-Barr virus genes in different cell types after microinjection of viral DNA. Proc Natl Acad Sci U S A 1980 1.59
34 Structure and evolution of two related transcription units of Epstein-Barr virus carrying small tandem repeats. J Virol 1985 1.59
35 New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and from normal individuals in endemic areas. J Gen Virol 1987 1.58
36 Identification of Epstein-Barr virus terminal protein 1 (TP1) in extracts of four lymphoid cell lines, expression in insect cells, and detection of antibodies in human sera. J Virol 1990 1.56
37 TPA-inducible Epstein-Barr virus genes in Raji cells and their regulation. Virology 1988 1.56
38 Episomal and integrated copies of Epstein-Barr virus coexist in Burkitt lymphoma cell lines. J Virol 1993 1.56
39 The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death. Oncogene 2007 1.55
40 Epstein-Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival. EMBO J 1996 1.53
41 Herpesvirus ateles DNA and its homology with Herpesvirus saimiri nucleic acid. J Virol 1978 1.53
42 Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc. Mol Cell Biol 1989 1.52
43 Identification and characterization of an Epstein-Barr virus nuclear antigen 2-responsive cis element in the bidirectional promoter region of latent membrane protein and terminal protein 2 genes. J Virol 1994 1.43
44 Two distant regions of the Epstein-Barr virus genome with sequence homologies have the same orientation and involve small tandem repeats. EMBO J 1982 1.43
45 Tetravinyl-tetramethylcyclo-tetrasiloxane (tetravinyl D4) is a mutagen in Rat2lambda lacI fibroblasts. Carcinogenesis 1998 1.41
46 Breakpoints of Burkitt's lymphoma t(8;22) translocations map within a distance of 300 kb downstream of MYC. Genes Chromosomes Cancer 1994 1.40
47 Individual tumors of multifocal EB virus-induced malignant lymphomas in tamarins arise from different B-cell clones. Science 1985 1.38
48 Both Epstein-Barr viral nuclear antigen 2 (EBNA2) and activated Notch1 transactivate genes by interacting with the cellular protein RBP-J kappa. Immunobiology 1997 1.37
49 Critical involvement of transmembrane tumor necrosis factor-alpha in endothelial programmed cell death mediated by ionizing radiation and bacterial endotoxin. Blood 1995 1.28
50 Human cytomegalovirus DNA sequences with homologies to the cellular genome. J Gen Virol 1984 1.27
51 Cytotoxic T lymphocytes show HLA-C-restricted recognition of EBV-bearing cells and allorecognition of HLA class I molecules presenting self-peptides. J Immunol 1992 1.21
52 c-myc activation renders proliferation of Epstein-Barr virus (EBV)-transformed cells independent of EBV nuclear antigen 2 and latent membrane protein 1. Proc Natl Acad Sci U S A 1996 1.20
53 Expression of a nuclear and a cytoplasmic Epstein-Barr virus early antigen after DNA transfer: cooperation of two distant parts of the genome for expression of the cytoplasmic antigen. Proc Natl Acad Sci U S A 1984 1.19
54 Rat monoclonal antibodies differentiating between the Epstein-Barr virus nuclear antigens 2A (EBNA2A) and 2B (EBNA2B). Virology 1995 1.18
55 Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation. FASEB J 2001 1.17
56 Activated Notch1 modulates gene expression in B cells similarly to Epstein-Barr viral nuclear antigen 2. J Virol 2000 1.16
57 The nuclear form of phospholipid hydroperoxide glutathione peroxidase is a protein thiol peroxidase contributing to sperm chromatin stability. Mol Cell Biol 2005 1.15
58 Epstein-Barr virus nuclear antigen 2 (EBNA2)-oestrogen receptor fusion proteins complement the EBNA2-deficient Epstein-Barr virus strain P3HR1 in transformation of primary B cells but suppress growth of human B cell lymphoma lines. J Gen Virol 1996 1.15
59 Functional replacement of the intracellular region of the Notch1 receptor by Epstein-Barr virus nuclear antigen 2. J Virol 1998 1.15
60 Deregulation of the proto-oncogene c-myc through t(8;22) translocation in Burkitt's lymphoma. Oncogene 1999 1.15
61 Epstein-Barr virus nuclear antigen 2 is a transcriptional suppressor of the immunoglobulin mu gene: implications for the expression of the translocated c-myc gene in Burkitt's lymphoma cells. EMBO J 1996 1.14
62 Crucial sequences within the Epstein-Barr virus TP1 promoter for EBNA2-mediated transactivation and interaction of EBNA2 with its responsive element. J Virol 1994 1.14
63 c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells. Nat Cell Biol 2001 1.13
64 Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents. Cell Death Differ 2007 1.13
65 c-myc and immunoglobulin kappa light chain constant genes are on the 8q+ chromosome of three Burkitt lymphoma lines with t(2;8) translocations. EMBO J 1984 1.12
66 BK virus: I. Seroepidemiologic studies and serologic response to viral infection. Med Microbiol Immunol 1978 1.12
67 Notch1IC partially replaces EBNA2 function in B cells immortalized by Epstein-Barr virus. J Virol 2001 1.12
68 Reversal of EBV immortalization precedes apoptosis in IL-6-induced human B cell terminal differentiation. Immunity 1997 1.11
69 Epstein-Barr virus nuclear antigen 2-estrogen receptor fusion proteins transactivate viral and cellular genes and interact with RBP-J kappa in a conditional fashion. Virology 1995 1.09
70 Attempts to demonstrate virus-specific sequences in human tumors. IV. EB viral DNA in European Burkitt lymphoma and immunoblastic lymphadenopathy with excessive plasmacytosis. Int J Cancer 1976 1.09
71 Transcription of c-myc in human mononuclear cells is regulated by an elongation block. Oncogene 1987 1.09
72 Effect of the diterpene ester TPA on Epstein-Barr virus antigen- and DNA synthesis in producer and nonproducer cell lines. Virology 1980 1.08
73 Activated mouse Notch1 transactivates Epstein-Barr virus nuclear antigen 2-regulated viral promoters. J Virol 1999 1.08
74 Inducible loss of NF-kappaB activity is associated with apoptosis and Bcl-2 down-regulation in Epstein-Barr virus-transformed B lymphocytes. Blood 2000 1.08
75 Variable breakpoints in Burkitt lymphoma cells with chromosomal t(8;14) translocation separate c-myc and the IgH locus up to several hundred kb. Hum Mol Genet 1992 1.05
76 Expression of normal and translocated c-myc alleles in Burkitt's lymphoma cells: evidence for different regulation. EMBO J 1989 1.04
77 Expression of P0- and P3-RNA from the normal and translocated c-myc allele in Burkitt's lymphoma cells. Oncogene 1990 1.02
78 Mapping chromosomal breakpoints of Burkitt's t(8;14) translocations far upstream of c-myc. Cancer Res 1992 1.02
79 Improving stable transfection efficiency: antioxidants dramatically improve the outgrowth of clones under dominant marker selection. Nucleic Acids Res 1998 1.01
80 Association of Epstein-Barr virus with nasopharyngeal carcinoma in Alaskan native patients: serum antibodies and tissue EBNA and DNA. Int J Cancer 1981 1.00
81 Gadd45 beta is a pro-survival factor associated with stress-resistant tumors. Oncogene 2007 0.99
82 Epstein-Barr virus-specific DNA polymerase in virus-nonproducer Raji cells. J Virol 1986 0.98
83 The role of Herpesvirus saimiri genomes in oncogenic transformation of primate cells. Bibl Haematol 1975 0.97
84 Epstein-Barr virus-positive Burkitt's lymphoma in a German woman during pregnancy. Blut 1980 0.96
85 Activated Notch1 can transiently substitute for EBNA2 in the maintenance of proliferation of LMP1-expressing immortalized B cells. J Virol 2001 0.96
86 Persistent Epstein-Barr virus infection and a histiocytic sarcoma in a renal transplant recipient. Cancer 1985 0.94
87 Phenotype versus immunoglobulin and T-cell receptor genotype of Hodgkin-derived cell lines: activation of immature lymphoid cells in Hodgkin's disease. Int J Cancer 1987 0.93
88 No homology detectable between Marek's disease virus (MDV) DNA and herpesvirus of the turkey (HVT) DNA. Med Microbiol Immunol 1979 0.92
89 No evidence for differences in the Epstein-Barr virus genome carried in Burkitt lymphoma cells and nonmalignant lymphoblastoid cells from the same patients. Proc Natl Acad Sci U S A 1984 0.92
90 Antagonistic effects of c-myc and Epstein-Barr virus latent genes on the phenotype of human B cells. Int J Cancer 2001 0.92
91 Antibody response against the Epstein-Barr virus-coded nuclear antigen2 (EBNA2) in different groups of individuals. Int J Cancer 1987 0.91
92 Characterization of hemopoietic cell populations from human cord blood expressing c-kit. Exp Hematol 1993 0.91
93 Presence of EBV-DNA sequences in nasopharyngeal cells of individuals without IgA-VCA antibodies. Int J Cancer 1983 0.91
94 Structure and function of herpesvirus saimira DNA. IARC Sci Publ 1975 0.91
95 Non-Hodgkin lymphomas of mice. Blood Cells Mol Dis 2001 0.90
96 Two antisense promoters in the immunoglobulin mu-switch region drive expression of c-myc in the Burkitt's lymphoma cell line BL67. Oncogene 1992 0.90
97 Expression of Epstein-Barr virus nuclear antigen-2 (EBNA2) induces CD21/CR2 on B and T cell lines and shedding of soluble CD21. Eur J Immunol 1995 0.90
98 Elevated expression of c-myc in lymphoblastoid cells does not support an Epstein-Barr virus latency III-to-I switch. J Gen Virol 2001 0.89
99 Establishment of spontaneously outgrowing lymphoblastoid cell lines with Cyclosporin A. Med Microbiol Immunol 1983 0.89
100 Variable morphology of human immunodeficiency virus-associated lymphomas with c-myc rearrangements. The French Study Group of Pathology for Human Immunodeficiency Virus-Associated Tumors, I. Blood 1993 0.89
101 Epstein-Barr virus nuclear antigens 1 and 2 in Burkitt lymphoma cell lines containing either 'A'- or 'B'-type virus. Intervirology 1988 0.88
102 Truncation does not abrogate transcriptional downregulation of the c-myc gene by sodium butyrate in Burkitt's lymphoma cells. EMBO J 1987 0.87
103 The Epstein-Barr virus nuclear antigen 2 (EBNA2), a protein required for B lymphocyte immortalization, induces the synthesis of type I interferon in Burkitt's lymphoma cell lines. Biol Chem 1999 0.87
104 Ionizing radiation induces human intercellular adhesion molecule-1 in vitro. J Invest Dermatol 1994 0.87
105 Apoptosis in Burkitt lymphoma cells is prevented by promotion of cysteine uptake. Int J Cancer 1998 0.87
106 BK virus: II. Serologic studies in children with congenital disease and patients with malignant tumors and immunodeficiencies. Med Microbiol Immunol 1978 0.86
107 The intron enhancer of the immunoglobulin kappa gene activates c-myc but does not induce the Burkitt-specific promoter shift. Oncogene 1991 0.85
108 Identification of two enhancer elements downstream of the human c-myc gene. Nucleic Acids Res 1995 0.85
109 c-myc expression is activated by the immunoglobulin kappa-enhancers from a distance of at least 30 kb but not by elements located within 50 kb of the unaltered c-myc locus in vivo. Oncogene 1996 0.85
110 [Severe chronic Epstein-Barr virus infection with natural killer cell defect]. Dtsch Med Wochenschr 1988 0.84
111 Expression of the Epstein-Barr virus (EBV) latent membrane protein is tightly regulated, independently of EB nuclear antigen 2 and of EBV integration or copy number. Virus Res 1993 0.83
112 Short-term assays for detection of conditional cancerogens. I. Construction of DR-CAT Raji cells and some of their characteristics as tester cells. Int J Cancer 1992 0.83
113 Irradiated fibroblasts protect Burkitt lymphoma cells from apoptosis by a mechanism independent of bcl-2. Int J Cancer 1993 0.83
114 The block of elongation in c-myc exon 1 is abolished in Burkitt's lymphoma cell lines with variant translocation. Oncogene 1988 0.82
115 Transcriptional activity across the Epstein-Barr virus genome in Raji cells during latency and after induction of an abortive lytic cycle. J Gen Virol 1991 0.82
116 Characterization of an EBV-like virus from African green monkey lymphoblasts. Virology 1980 0.81
117 Detection of Epstein-Barr viral DNA internal repeats in the nasopharyngeal mucosa of Chinese with IgA/EBV-specific antibodies. Int J Cancer 1982 0.80
118 In vitro mutagenicity of the plasmacytomagenic agent pristane (2,6,10,14-tetramethylpentadecane). Cancer Lett 1997 0.80
119 [Epstein-Barr virus associated Burkitt's lymphoma in a French child (author's transl)]. Nouv Presse Med 1979 0.79
120 Epstein-Barr virus activators, mutagens and volatile nitrosamines in preserved food samples from high-risk areas for nasopharyngeal carcinoma. IARC Sci Publ 1991 0.78
121 Characterization of macromolecular lignins as Epstein-Barr virus inducer in foodstuff associated with nasopharyngeal carcinoma risk. Carcinogenesis 1995 0.78
122 Epstein-Barr virus terminal protein gene transcription is dependent on EBNA2 expression and provides evidence for viral integration into the host genome. Curr Top Microbiol Immunol 1990 0.78
123 Influence of bacterial endotoxin on radiation-induced activation of human endothelial cells in vitro and in vivo: interleukin-10 protects against transendothelial migration. Transplantation 1997 0.78
124 Protein kinase C activation is involved in ultraviolet B irradiation-induced endothelial cell ICAM-1 up-regulation and lymphocyte-endothelium interaction in vitro. Scand J Immunol 1996 0.78
125 Influence of bacterial endotoxin on radiation-induced activation of human endothelial cells in vitro and in vivo: protective role of IL-10. Transplantation 1996 0.78
126 Validation of two test systems for detecting tumor promoters and EBV inducers: comparative responses of several agents in DR-CAT Raji cells and in human granulocytes. Carcinogenesis 1993 0.78
127 EBNA2 and c-myc in B cell immortalization by Epstein-Barr virus and in the pathogenesis of Burkitt's lymphoma. Curr Top Microbiol Immunol 1999 0.77
128 Clustered somatic mutations in and around first exon of non-rearranged c-myc in Burkitt lymphoma with t(8;22) translocation. Nucleic Acids Res 1987 0.77
129 Regulatory elements in the immunoglobulin kappa locus induce c-myc activation in Burkitt's lymphoma cells. Curr Top Microbiol Immunol 1995 0.77
130 Elevated mutant frequencies in lymphoid tissues persist throughout plasmacytoma development in BALB/c.lambdaLIZ mice. Cancer Res 1999 0.77
131 Consequences of antigen self-presentation by tumor-specific cytotoxic T cells. Immunobiology 2000 0.77
132 Long-range chromatin analysis of the human MYC locus by pulsed-field gel electrophoresis. Genes Chromosomes Cancer 1996 0.77
133 Integration of EBV in Burkitt's lymphoma cells. Curr Top Microbiol Immunol 1992 0.76
134 Differential role of protein kinase C in cytokine induced lymphocyte-endothelium interaction in vitro. Scand J Immunol 1994 0.76
135 Nucleic acid hybridization for the detection of viral genomes. Curr Top Microbiol Immunol 1983 0.76
136 Among 17 inducers of differentiation only sodium butyrate causes a permanent down-regulation of c-myc in Burkitt's lymphoma. Int J Cancer 1995 0.76
137 Do infections induce monoclonal immunoglobulin components? Clin Exp Immunol 1990 0.75
138 The role of Epstein-Barr virus in human B cell malignancies. Haematologica 1988 0.75
139 [Virologic-serologic diagnosis of nasopharyngeal cancer]. Strahlentherapie Sonderb 1984 0.75
140 The electron-microscopic structure of nucleoprotein fibrils from metaphase chromosomes treated with salt. Chromosoma 1973 0.75
141 Cloning of phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an anti-apoptotic and growth promoting gene of Burkitt lymphoma cells. Biofactors 2001 0.75
142 Structural organization and expression of the Epstein-Barr virus genome. Haematol Blood Transfus 1983 0.75
143 [On the mechanism of action of inducer substances. I. Fractionation of calf thymus chromatin and characterization of a specific DNA-protein complex]. Hoppe Seylers Z Physiol Chem 1967 0.75
144 t(2;8) variant translocation in Burkitt's lymphoma: mapping of chromosomal breakpoints by in situ hybridization. Int J Cancer 1989 0.75
145 Concerning the specificity of histone and non-histone dissociation from calf thymus chromatin by salt. Biochim Biophys Acta 1972 0.75
146 [Burkitt lymphoma of African type in Europe (author's transl)]. Dtsch Med Wochenschr 1980 0.75
147 Inducible mutagenesis in TEPC 2372, a mouse plasmacytoma cell line that harbors the transgenic shuttle vector lambdaLIZ. Mutat Res 2001 0.75
148 Molecular analysis of Hodgkin's disease-derived cell lines. Hematol Oncol 1988 0.75
149 Transgenic shuttle vector assays for assessing oxidative B-cell mutagenesis in vivo. Curr Top Microbiol Immunol 1999 0.75
150 Association of elevated mutagenesis in the spleen with genetic susceptibility to induced plasmacytoma development in mice. Cancer Res 1998 0.75
151 A computer-assisted two-dimensional gel electrophoresis approach for studying the variations in protein expression related to an induced functional repression of NFkappaB in lymphoblastoid cell lines. Electrophoresis 1999 0.75
152 Attachment of antinuclear antibodies to nasopharyngeal carcinoma or other cells during preparation of biopsy imprints. J Natl Cancer Inst 1986 0.75
153 Epstein-Barr virus genomes and their biological functions: a review. IARC Sci Publ 1978 0.75
154 A new lymphoid cell line, Reh 6, with characteristics of non-T and non-B cells, lacking the Epstein-Barr virus genome and derived from human acute lymphoblastic leukemia. Intervirology 1978 0.75
155 Episomal viral DNA in herpesvirus saimiri-transformed lymphoid cell lines. IARC Sci Publ 1978 0.75
156 Cytotoxicity and membrane damage in vitro by inclusion complexes between gamma-cyclodextrin and siloxanes. Curr Top Microbiol Immunol 1996 0.75
157 Structure-activity relationship of 17 structural analogues of n-butyric acid upon c-myc expression. Int J Cancer 1996 0.75