Published in Br J Pharmacol on July 01, 1992
Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses. Proc Natl Acad Sci U S A (2003) 1.19
Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders. Curr Pharm Des (2008) 1.13
Overview of brain microdialysis. Curr Protoc Neurosci (2009) 1.05
Mediation of the neuroprotective action of R-phenylisopropyl-adenosine through a centrally located adenosine A1 receptor. Br J Pharmacol (1993) 0.80
Overview of microdialysis. Curr Protoc Neurosci (2001) 0.78
Alkylxanthine adenosine antagonists and epileptiform activity in rat hippocampal slices in vitro. Exp Brain Res (1997) 0.75
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem (1984) 3.39
The physiological role of adenosine in the central nervous system. Int Rev Neurobiol (1985) 1.71
Adenosine-activated potassium conductance in cultured striatal neurons. Proc Natl Acad Sci U S A (1985) 1.48
Purine levels in the intact rat brain. Studies with an implanted perfused hollow fibre. Neurosci Lett (1982) 1.34
Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis. J Neurochem (1988) 1.28
Brain adenosine production in the rat during 60 seconds of ischemia. Circ Res (1979) 1.28
Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism. Acta Physiol Scand (1991) 1.27
Increases in cerebral interstitial fluid adenosine concentration during hypoxia, local potassium infusion, and ischemia. J Cereb Blood Flow Metab (1986) 1.26
Neurobiology. Taking apart NMDA receptors. Nature (1987) 1.22
Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia. J Neurochem (1987) 1.22
Adenosine decreases aspartate and glutamate release from rat hippocampal slices. Eur J Pharmacol (1984) 1.19
Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments. J Cereb Blood Flow Metab (1985) 1.18
Determination of brain interstitial concentrations by microdialysis. J Neurochem (1989) 1.11
Ischemia-induced neuronal cell death, calcium accumulation, and glial response in the hippocampus of the Mongolian gerbil and protection by propentofylline (HWA 285). J Cereb Blood Flow Metab (1987) 1.06
Glutamatergic control of dopamine release in the rat striatum: evidence for presynaptic N-methyl-D-aspartate receptors on dopaminergic nerve terminals. J Neurochem (1991) 1.04
Endogenous adenosine as a modulator of hippocampal acetylcholine release. Naunyn Schmiedebergs Arch Pharmacol (1984) 1.01
Effects of in vivo administration of kainic acid on the extracellular amino acid pool in the rabbit hippocampus. J Neurochem (1983) 1.01
Endogenous adenosine inhibits hippocampal CA1 neurones: further evidence from extra- and intracellular recording. Naunyn Schmiedebergs Arch Pharmacol (1988) 1.01
Increases in cerebral cortical perfusate adenosine and inosine concentrations during hypoxia and ischemia. J Cereb Blood Flow Metab (1987) 0.98
An adenosine analogue, 2-chloroadenosine, protects against long term development of ischaemic cell loss in the rat hippocampus. Neurosci Lett (1987) 0.97
Regulation of glutamate and aspartate release from slices of the hippocampal CA1 area: effects of adenosine and baclofen. J Neurochem (1988) 0.95
Inhibition of [3H] glutamate release from rat hippocampal slices by L-phenylisopropyladenosine. Acta Physiol Scand (1985) 0.93
Protective effect of cyclohexyl adenosine in treatment of cerebral ischemia in gerbils. Neuroscience (1989) 0.93
Release-enhancing glycine-dependent presynaptic NMDA receptors exist on noradrenergic terminals of hippocampus. Eur J Pharmacol (1990) 0.93
A1 and A2 adenosine receptors modulate acetylcholine release from brain slices. Eur J Pharmacol (1984) 0.92
Presynaptic NMDA receptors stimulate noradrenaline release in the cerebral cortex. Eur J Pharmacol (1990) 0.92
Regional differences in the electrically stimulated release of endogenous and radioactive adenosine and purine derivatives from rat brain slices. Naunyn Schmiedebergs Arch Pharmacol (1990) 0.92
Adenosine formation and release by embryonic chick neurons and glia in cell culture. J Neurochem (1989) 0.91
Release of purines, noradrenaline, and GABA from rat hippocampal slices by field stimulation. J Neurochem (1985) 0.89
Brain adenosine and transmitter amino acid release from the ischemic rat cerebral cortex: effects of the adenosine deaminase inhibitor deoxycoformycin. J Neurochem (1991) 0.89
N-methyl-D-aspartate, kainate and quisqualate release endogenous adenosine from rat cortical slices. Neuroscience (1990) 0.88
Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia. Br J Pharmacol (1990) 0.86
Inhibition of noradrenaline release from hippocampal slices by a stable adenosine analogue. Acta Physiol Scand Suppl (1983) 0.85
Propentofylline (HWA 285) protects hippocampal neurons of Mongolian gerbils against ischemic damage in the presence of an adenosine antagonist. Neurosci Lett (1988) 0.84
Role of excitatory amino acid receptors in K+- and glutamate-evoked release of endogenous adenosine from rat cortical slices. J Neurochem (1990) 0.84
Characteristics of the release of adenosine from slices of rat cerebral cortex. J Physiol (1980) 0.84
Nature of extrasynaptosomal accumulation of endogenous adenosine evoked by K+ and veratridine. J Neurochem (1985) 0.82
2-chloroadenosine attenuates kainic acid-induced toxicity within the rat straitum: relationship to release of glutamate and Ca2+ influx. Br J Pharmacol (1989) 0.81
Effects of deoxycoformycin on adenosine, inosine, hypoxanthine, xanthine, and uric acid release from the hypoxemic rat cerebral cortex. J Cereb Blood Flow Metab (1988) 0.81
Quinolinic acid neurotoxicity: protection by intracerebral phenylisopropyladenosine (PIA) and potentiation by hypotension. Neurosci Lett (1989) 0.81
Deoxycoformycin antagonizes ischemia-induced neuronal degeneration. Brain Res Bull (1989) 0.81
Depolarization-evoked accumulation of cyclic AMP in brain slices: the requisite intermediate adenosine is not derived from hydrolysis of released ATP. J Neurochem (1980) 0.80
Presynaptic adenosine A2 and N-methyl-D-aspartate receptors regulate dopamine synthesis in rat striatal synaptosomes. J Neurochem (1991) 0.80
Veratridine-induced release in vivo and in vitro of amino acids in the rabbit olfactory bulb. Brain Res (1984) 0.79
N-methyl-D-aspartate releases excitatory amino acids in rat corpus striatum in vivo. J Neurochem (1991) 0.78
Changes in the state of the excitatory synaptic system in the hippocampus on prolonged exposure to excitatory amino acids and antagonists. Neurosci Lett (1988) 0.77
Adenosine and glutamate modulate each other's release from rat hippocampal synaptosomes. J Neurochem (1991) 0.77
Diffuse axonal injury and traumatic coma in the primate. Ann Neurol (1982) 4.08
Diffuse axonal injury due to nonmissile head injury in humans: an analysis of 45 cases. Ann Neurol (1982) 3.82
Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury. Nat Med (1995) 3.77
Diffuse axonal injury in head injury: definition, diagnosis and grading. Histopathology (1989) 3.24
Patients with head injury who talk and die. Lancet (1975) 3.20
Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab (1981) 3.18
An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res (1982) 2.99
Diffuse brain damage of immediate impact type. Its relationship to 'primary brain-stem damage' in head injury. Brain (1977) 2.96
Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression. Brain Pathol (1998) 2.73
Neocortical death after cardiac arrest. A clinical, neurophysiological, and neuropathological report of two cases. Lancet (1971) 2.52
beta A4 amyloid protein deposition in brain after head trauma. Lancet (1991) 2.41
Association of interleukin-1 gene polymorphisms with Alzheimer's disease. Ann Neurol (2000) 2.37
Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury. Neurosci Lett (1993) 2.35
Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry (1994) 2.24
Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS. Eur J Pharmacol (1981) 2.02
High frequency of apolipoprotein E epsilon 2 allele in hemorrhage due to cerebral amyloid angiopathy. Ann Neurol (1997) 2.00
Physiological roles for adenosine and adenosine 5'-triphosphate in the nervous system. Neuroscience (1981) 1.85
Sequences specific for enterovirus detected in spinal cord from patients with motor neurone disease. BMJ (1994) 1.83
Ischaemic brain damage in fatal non-missile head injuries. J Neurol Sci (1978) 1.74
Experimental models of traumatic brain injury: do we really need to build a better mousetrap? Neuroscience (2005) 1.71
Ischaemic brain damage in fatal head injuries. Lancet (1971) 1.69
The neuropathology of the vegetative state after an acute brain insult. Brain (2000) 1.67
Progressive atrophy and neuron death for one year following brain trauma in the rat. J Neurotrauma (1997) 1.64
Brain damage in fatal non-missile head injury. J Clin Pathol (1980) 1.58
Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus. Nature (1981) 1.50
The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat. Ann Neurol (1988) 1.49
The contusion index: a reappraisal in human and experimental non-missile head injury. Neuropathol Appl Neurobiol (1985) 1.49
Long-term intracerebral inflammatory response after traumatic brain injury. Forensic Sci Int (2004) 1.48
Ischaemic brain damage of cerebral perfusion failure type after treatment of severe hypertension. Br Med J (1975) 1.46
Apoptosis after traumatic brain injury. J Neurotrauma (2000) 1.45
Increased kynurenic acid levels in Huntington's disease. Lancet (1988) 1.43
Head injury in man and experimental animals: neuropathology. Acta Neurochir Suppl (Wien) (1983) 1.42
Neuropathological sequelae of traumatic brain injury: relationship to neurochemical and biomechanical mechanisms. Lab Invest (1996) 1.38
Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat. J Neurosci (1996) 1.37
Effects of large doses of colistin sulphomethate sodium on renal function. Br Med J (1970) 1.37
Internalization of neuronal plasma membrane ricin receptors into the Golgi apparatus. Exp Cell Res (1975) 1.36
Effects of acutely induced hypertension in cats on pial arteriolar caliber, local cerebral blood flow, and the blood-brain barrier. Circ Res (1976) 1.35
Quinolinic acid and other kynurenines in the central nervous system. Neuroscience (1985) 1.34
Efflux characteristics of isotopically labelled gamma-aminobutyric acid (GABA) and L-glutamate in the rat cuneate nucleus [proceedings]. Br J Pharmacol (1977) 1.32
Microglial interleukin-1 alpha expression in human head injury: correlations with neuronal and neuritic beta-amyloid precursor protein expression. Neurosci Lett (1994) 1.32
The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms. Neuropathol Appl Neurobiol (1998) 1.32
The apolipoprotein E epsilon2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage. J Neuropathol Exp Neurol (1999) 1.31
Tryptophan metabolism and oxidative stress in patients with Huntington's disease. J Neurochem (2005) 1.31
Diffuse axonal injury in head injuries caused by a fall. Lancet (1984) 1.29
Diffuse axonal injury in non-missile head injury. J Neurol Neurosurg Psychiatry (1991) 1.28
Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia. J Neurol Neurosurg Psychiatry (1987) 1.27
Traumatic axonal injury: practical issues for diagnosis in medicolegal cases. Neuropathol Appl Neurobiol (2000) 1.26
Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia. Stroke (2001) 1.24
The release of endothelium-derived relaxant factor is calcium dependent. Blood Vessels (1985) 1.23
Amyloid beta-protein, APOE genotype and head injury. Ann N Y Acad Sci (1996) 1.21
The neuropathology of the vegetative state after head injury. J Clin Pathol (1999) 1.21
Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system. J Pharmacol Exp Ther (1983) 1.19
Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences. J Cereb Blood Flow Metab (1993) 1.18
Cortical pyramidal tract interneurones and their sensitivity to L-glutamic acid. J Physiol (1973) 1.18
The neuroinflammatory response in humans after traumatic brain injury. Neuropathol Appl Neurobiol (2013) 1.18
Antagonism by clonidine of neuronal depressant responses to adenosine, adenosine-5'-monophosphate and adenosine triphosphate. Br J Pharmacol (1978) 1.17
Aging-associated changes in human brain. J Neuropathol Exp Neurol (1997) 1.17
Axonal injury: a universal consequence of fatal closed head injury? Acta Neuropathol (1995) 1.17
Axonal injury in the optic nerve: a model simulating diffuse axonal injury in the brain. J Neurosurg (1989) 1.15
Brain damage in non-missile head injury secondary to high intracranial pressure. Neuropathol Appl Neurobiol (1987) 1.15
Correlation between angiographic findings and the ischaemia of head injury. J Neurol Neurosurg Psychiatry (1978) 1.15
A beta 42 is the predominant form of amyloid beta-protein in the brains of short-term survivors of head injury. Neuroreport (1997) 1.15
Effects of hemorrhagic hypotension on the cerebral circulation. I. Cerebral blood flow and pial arteriolar caliber. Stroke (1980) 1.13
Antioxidants and fatty acids in the amelioration of rheumatoid arthritis and related disorders. Br J Nutr (2001) 1.13
Effects of dexamethasone and betamethasone on in vitro cultures from human astrocytoma. Br J Cancer (1977) 1.12
Loss of axonal microtubules and neurofilaments after stretch-injury to guinea pig optic nerve fibers. J Neurotrauma (1997) 1.12
Intracranial haemorrhage induced at arterial pressure in the rat. Part 2: Short term changes in local cerebral blood flow measured by autoradiography. Neurol Res (1984) 1.12
Changes in the hippocampus and the cerebellum resulting from hypoxic insults: frequency and distribution. Acta Neuropathol (1989) 1.11
Tau immunohistochemistry in acute brain injury. Neuropathol Appl Neurobiol (2003) 1.09
Microiontophoretic studies of the effects of cylic nucleotides on excitability of neurones in the rat cerebral cortex. J Physiol (1977) 1.09
Tryptophan metabolism and oxidative stress in patients with chronic brain injury. Eur J Neurol (2006) 1.08
Actions of adenine dinucleotides on the vas deferens, guinea-pig taenia caeci and bladder. Eur J Pharmacol (1981) 1.08
Deep intracerebral (basal ganglia) haematomas in fatal non-missile head injury in man. J Neurol Neurosurg Psychiatry (1986) 1.08
Oxidative stress as a mechanism for quinolinic acid-induced hippocampal damage: protection by melatonin and deprenyl. Br J Pharmacol (1999) 1.08
Is beta-APP a marker of axonal damage in short-surviving head injury? Acta Neuropathol (1996) 1.08
The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines. Br J Pharmacol (1990) 1.07
Focal cerebral ischaemia in the rat: 2. Regional cerebral blood flow determined by [14C]iodoantipyrine autoradiography following middle cerebral artery occlusion. J Cereb Blood Flow Metab (1981) 1.07
Adenosine inhibition of gamma-aminobutyric acid release from slices of rat cerebral cortex. Br J Pharmacol (1980) 1.07
The hemodynamic effects of internal carotid artery stenosis and occlusion. J Neurosurg (1987) 1.07
Cholinergic mechanisms in the rat somatosensory cerebral cortex. J Physiol (1972) 1.07
There is differential loss of pyramidal cells from the human hippocampus with survival after blunt head injury. J Neuropathol Exp Neurol (2003) 1.06
Craniocerebral trauma: protection and retrieval of the neuronal population after injury. Neurosurgery (1998) 1.06
Glial swelling following human cerebral contusion: an ultrastructural study. J Neurol Neurosurg Psychiatry (1991) 1.05
Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke (1990) 1.05
In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man. Acta Neuropathol (2001) 1.05
Altered kynurenine metabolism correlates with infarct volume in stroke. Eur J Neurosci (2007) 1.05
Neuropathology in vegetative and severely disabled patients after head injury. Neurology (2001) 1.04
Interrelationship between differentiation and malignancy-associated properties in glioma. Br J Cancer (1984) 1.04
Cytochemical evidence for redistribution of membrane pump calcium-ATPase and ecto-Ca-ATPase activity, and calcium influx in myelinated nerve fibres of the optic nerve after stretch injury. J Neurocytol (1995) 1.04
Glutamate as the neurotransmitter of cerebellar granule cells in the rat: electrophysiological evidence. Br J Pharmacol (1979) 1.03
Intracranial haemorrhage induced at arterial pressure in the rat. Part 1: Description of technique, ICP changes and neuropathological findings. Neurol Res (1984) 1.03
Responses of neurones in the cerebral cortex and caudate nucleus to amantadine, amphetamine and dopamine. Br J Pharmacol (1976) 1.02
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones. Neurosci Lett (1981) 1.02
Quinolinic acid: regional variations in neuronal sensitivity. Brain Res (1983) 1.02
The effect of congenital and adult-acquired Toxoplasma infections on activity and responsiveness to novel stimulation in mice. Ann Trop Med Parasitol (1983) 1.02
Amino acid pharmacology in neocortical slices: evidence for bimolecular actions from an extension of the Hill and Gaddum-Schild equations. Br J Pharmacol (1988) 1.02
Acceleration induced head injury in the monkey.I. The model, its mechanical and physiological correlates. Acta Neuropathol Suppl (1981) 1.01
Microscopic diffuse axonal injury in cases of head injury. Med Sci Law (1985) 1.01
A DNA analysis program designed for computer novices working in an industrial-research environment. Nucleic Acids Res (1984) 1.01
Action of purine and pyrimidine nucleotides on the rat superior cervical ganglion. Br J Pharmacol (1993) 1.00