PubRank

P Peltomäki

Author PubWeight™ 131.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Clues to the pathogenesis of familial colorectal cancer. Science 1993 14.52
2 Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993 9.93
3 Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 2000 8.58
4 Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med 1998 8.47
5 Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer. Gastroenterology 2000 8.41
6 Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer 1999 6.73
7 Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res 1993 4.93
8 Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat Med 1996 4.87
9 Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nat Genet 1995 4.01
10 Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res 1994 3.25
11 BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing. J Med Genet 2004 2.75
12 Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer. Nat Genet 1994 2.08
13 Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers. Am J Pathol 2000 2.03
14 Microsatellite instability as an indicator of hereditary susceptibility to colon cancer. Gastroenterology 1995 1.97
15 Molecular screening for hereditary nonpolyposis colorectal cancer: a prospective, population-based study. J Clin Oncol 2001 1.97
16 MSH2 and MLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis. Genes Chromosomes Cancer 1997 1.83
17 DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancer. Hum Mol Genet 1996 1.64
18 Age and origin of two common MLH1 mutations predisposing to hereditary colon cancer. Am J Hum Genet 1996 1.58
19 Molecular genetic changes in human male germ cell tumors. Lab Invest 1995 1.53
20 Predictive genetic testing for hereditary non-polyposis colorectal cancer: uptake and long-term satisfaction. Int J Cancer 2000 1.49
21 Deletion of 1p loci and microsatellite instability in colorectal polyps. Genes Chromosomes Cancer 1995 1.43
22 Nuclear and mitochondrial genome instability in human breast cancer. Cancer Res 2000 1.38
23 Genetics of hereditary colon cancer. Annu Rev Genet 1995 1.36
24 A novel approach to estimate the proportion of hereditary nonpolyposis colorectal cancer of total colorectal cancer burden. Cancer Detect Prev 1994 1.36
25 Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers. Proc Natl Acad Sci U S A 1999 1.28
26 The InSiGHT database: utilizing 100 years of insights into Lynch syndrome. Fam Cancer 2013 1.27
27 The role of hPMS1 and hPMS2 in predisposing to colorectal cancer. Cancer Res 2001 1.20
28 Linkage analysis in a large Swedish family supports the presence of a susceptibility locus for adenoma and colorectal cancer on chromosome 9q22.32-31.1. J Med Genet 2006 1.18
29 Genetic and clinical characterisation of familial adenomatous polyposis: a population based study. Gut 2002 1.16
30 CYCLIN D1 as a genetic modifier in hereditary nonpolyposis colorectal cancer. Cancer Res 2001 1.14
31 Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families. Proc Natl Acad Sci U S A 1994 1.14
32 Pallister-Killian syndrome: cytogenetic and molecular studies. Clin Genet 1987 1.13
33 A new tool for the rapid cloning of amplified and hypermethylated human DNA sequences from restriction landmark genome scanning gels. Genomics 1999 1.12
34 DNA copy number changes in malignant ovarian germ cell tumors. Cancer Res 2000 1.07
35 MSH6 and MSH3 are rarely involved in genetic predisposition to nonpolypotic colon cancer. Cancer Res 2001 1.06
36 Molecular mapping of the putative gonadoblastoma locus on the Y chromosome. Genes Chromosomes Cancer 1995 1.06
37 Is gastric cancer part of the tumour spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study. Gut 2007 1.03
38 Mutation sharing, predominant involvement of the MLH1 gene and description of four novel mutations in hereditary nonpolyposis colorectal cancer. Mutations in brief no. 144. Online. Hum Mutat 1998 0.98
39 Direct contact in inviting high-risk members of hereditary colon cancer families to genetic counselling and DNA testing. J Med Genet 2007 0.97
40 Mismatch repair genes and mononucleotide tracts as mutation targets in colorectal tumors with different degrees of microsatellite instability. Oncogene 1998 0.97
41 Sporadic gastric carcinomas with microsatellite instability display a particular clinicopathologic profile. Int J Cancer 1995 0.96
42 Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach. Oncogene 2007 0.96
43 Genetic polymorphisms in carcinogen metabolism and their association to hereditary nonpolyposis colon cancer. Gastroenterology 1998 0.95
44 Microsatellite instability and hereditary non-polyposis colon cancer. J Pathol 1995 0.94
45 Missense and nonsense mutations in codon 659 of MLH1 cause aberrant splicing of messenger RNA in HNPCC kindreds. Genes Chromosomes Cancer 1999 0.94
46 Mutation of an mutL homologue in a Navajo family with hereditary nonpolyposis colorectal cancer. J Natl Cancer Inst 1994 0.92
47 Lack of MSH2 and MSH6 characterizes endometrial but not colon carcinomas in hereditary nonpolyposis colorectal cancer. Cancer Res 2001 0.92
48 Evaluation of a counselling protocol for predictive genetic testing for hereditary non-polyposis colorectal cancer. J Med Genet 2000 0.88
49 Genes involved in hereditary nonpolyposis colorectal carcinoma. Anticancer Res 1994 0.88
50 Genomic instability and target gene mutations in colon cancers with different degrees of allelic shifts. Genes Chromosomes Cancer 2000 0.86
51 Microsatellite instability in cervical and endometrial carcinomas. Int J Cancer 1997 0.86
52 Potential role of a navigator gene NAV3 in colorectal cancer. Br J Cancer 2011 0.85
53 Molecular cytogenetic study of patients with Pallister-Killian syndrome. Hum Genet 1993 0.84
54 Novel splicing associations of hereditary colon cancer related DNA mismatch repair gene mutations. J Med Genet 2004 0.84
55 The genetics of hereditary common cancers. Curr Opin Genet Dev 1998 0.84
56 Linkage analysis identifies gene carriers among members of families with hereditary nonpolyposis colorectal cancer. Gastroenterology 1996 0.79
57 Demethylation of two specific DNA sequences in expressed human immunoglobulin light kappa constant genes. Somat Cell Mol Genet 1988 0.79
58 Ethnic variation in the prevalence of AZF deletions in testicular cancer. Mutat Res 2004 0.78
59 Low frequency of hMSH2 mutations in Swedish HNPCC families. Int J Cancer 1997 0.78
60 [A breakthrough in solving the genetic background of colon cancer]. Duodecim 1993 0.78
61 The pattern of methylation in rearranged and germ-line human immunoglobulin constant mu genes. Biochim Biophys Acta 1987 0.78
62 Hereditary nonpolyposis colorectal cancer. Scand J Gastroenterol 1994 0.77
63 Two novel human B-cell lymphoma lines of lymphatic follicle origin: cytogenetic, molecular genetic and histopathological characterisation. Eur J Haematol 1994 0.77
64 Hereditary nonpolyposis colorectal cancer (Lynch syndrome II) in Uruguay. Dis Colon Rectum 2000 0.75
65 [What's new in the genetics of familial colon cancer?]. Duodecim 1991 0.75
66 [Goodness in nurse's heart matters. What is goodness in nursing practice?]. Sairaanhoitaja 1997 0.75
67 [Chromosome and gene abnormalities in malignant blood diseases]. Duodecim 1989 0.75
68 [The mismatch-repair genes and colon cancer]. Duodecim 1996 0.75
69 Characterization of neoplastic and reactive cells in T-cell lymphomas with cytogenetic, surface marker, and DNA methods. Br J Haematol 1989 0.75
70 [The use of polymerase chain reaction in the diagnosis of non-Hodgkin's lymphoma]. Duodecim 1990 0.75
71 Effect of a low-molecular-weight B cell growth factor on the proliferation of normal and neoplastic lymphocytes in lymphomas. Cancer Genet Cytogenet 1990 0.75
72 Chromosomal abnormality limited to T4 lymphocytes in a patient with T-cell chronic lymphocytic leukaemia. Eur J Haematol 1990 0.75
73 Molecular determinants of colon cancer susceptibility in the East and West. Curr Mol Med 2017 0.75
74 Major and minor breakpoint sites of chromosomal translocation t(14;18) in subtypes of non-Hodgkin's lymphomas. Leuk Res 1994 0.75
75 Karyotype and BCR studies after bone marrow transplantation for chronic myeloid leukaemia. Bone Marrow Transplant 1991 0.75
76 Mutation analysis of SMAD2, SMAD3, and SMAD4 genes in hereditary non-polyposis colorectal. J Med Genet 2000 0.75
77 Screening families with endometrial and colorectal cancers for germline mutations. J Med Genet 2001 0.75
78 Genetic changes associated with colon tumor development. Ann Chir Gynaecol 2000 0.75