Molecular characterization of a large homozygous deletion in the small cell lung cancer cell line U2020: a strategy for cloning the putative tumor suppressor gene.

PubWeight™: 0.83‹?›

🔗 View Article (PMID 1381947)

Published in Genes Chromosomes Cancer on September 01, 1992

Authors

F Latif1, K Tory, W S Modi, S L Graziano, G Gamble, J Douglas, A C Heppell-Parton, P H Rabbitts, B Zbar, M I Lerman

Author Affiliations

1: Laboratory of Immunobiology, Frederick Cancer Research and Development Center, Maryland 21702-1201.

Articles by these authors

Identification of the von Hippel-Lindau disease tumor suppressor gene. Science (1993) 11.95

Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat Genet (1994) 10.14

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci U S A (1994) 8.47

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science (1987) 6.89

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet (1997) 6.83

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans. Cell (1993) 6.83

Per-contact risk of human immunodeficiency virus transmission between male sexual partners. Am J Epidemiol (1999) 6.25

The Heidelberg classification of renal cell tumours. J Pathol (1997) 5.36

Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE. FEBS Lett (1989) 4.75

Medium for the propagation and assay of lactic and other phages. Lab Pract (1974) 4.19

Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization. Science (1986) 4.17

Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J Natl Cancer Inst (2001) 4.14

Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas. Cancer Res (1994) 3.62

Localization of polymorphic DNA probes frequently deleted in lung carcinoma. Hum Genet (1989) 3.51

Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma. Nature (1987) 3.46

Preserving renal function in adults with hypertension and diabetes: a consensus approach. National Kidney Foundation Hypertension and Diabetes Executive Committees Working Group. Am J Kidney Dis (2000) 3.37

A critical review of the use of glycerophosphates in microbiological media. Lab Pract (1971) 3.15

Birt-Hogg-Dubé syndrome: a novel marker of kidney neoplasia. Arch Dermatol (1999) 3.14

Managed care, time pressure, and physician job satisfaction: results from the physician worklife study. J Gen Intern Med (2000) 3.02

Novel mutations of the MET proto-oncogene in papillary renal carcinomas. Oncogene (1999) 3.01

A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group. N Engl J Med (1993) 2.98

Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation. Proc Natl Acad Sci U S A (2001) 2.94

Activating mutations for the met tyrosine kinase receptor in human cancer. Proc Natl Acad Sci U S A (1997) 2.92

Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer. Am J Pathol (2001) 2.86

Net costs from three perspectives of using low versus high osmolality contrast medium in diagnostic angiocardiography. J Am Coll Cardiol (1993) 2.72

Birt-Hogg-Dubé syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2. Am J Hum Genet (2001) 2.68

Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma. Biochim Biophys Acta (1996) 2.64

Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor gene. Hum Mutat (1998) 2.64

High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res (2000) 2.60

The work lives of women physicians results from the physician work life study. The SGIM Career Satisfaction Study Group. J Gen Intern Med (2000) 2.54

Metabolism of c-myc gene products: c-myc mRNA and protein expression in the cell cycle. EMBO J (1985) 2.53

Identification of intragenic mutations in the von Hippel-Lindau disease tumour suppressor gene and correlation with disease phenotype. Hum Mol Genet (1994) 2.52

Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas. Nat Genet (1998) 2.50

Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer. JAMA (1995) 2.43

von Hippel-Lindau disease: genetic, clinical, and imaging features. Radiology (1995) 2.38

A novel germ line juxtamembrane Met mutation in human gastric cancer. Oncogene (2000) 2.35

One hundred kidney transplants in the Belfast city hospital. Lancet (1977) 2.31

Refining the measurement of physician job satisfaction: results from the Physician Worklife Survey. SGIM Career Satisfaction Study Group. Society of General Internal Medicine. Med Care (1999) 2.29

Measuring physician job satisfaction in a changing workplace and a challenging environment. SGIM Career Satisfaction Study Group. Society of General Internal Medicine. Med Care (1999) 2.26

Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. Oncogene (2001) 2.22

Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes. Proc Natl Acad Sci U S A (1998) 2.20

Neuropsychiatric events at the time of diagnosis of systemic lupus erythematosus: an international inception cohort study. Arthritis Rheum (2007) 2.18

BCG and cancer (first of two parts). N Engl J Med (1974) 2.13

Randomized, controlled trial of integrated heart failure management: The Auckland Heart Failure Management Study. Eur Heart J (2002) 2.13

Truncation of exon 1 from the c-myc gene results in prolonged c-myc mRNa stability. EMBO J (1985) 2.10

Magnesium and the obstetric anaesthetist. Int J Obstet Anesth (2012) 2.09

Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages. Cell Immunol (1974) 2.07

Suppression of tumor growth at the site of infection with living Bacillus Calmette-Guérin. J Natl Cancer Inst (1971) 2.04

Homology between the KpnI primate and BamH1 (M1F-1) rodent families of long interspersed repeated sequences. Nucleic Acids Res (1983) 2.03

Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex. Proc Natl Acad Sci U S A (1988) 1.95

The use of chromosomal translocations to study human immunoglobulin gene organization: mapping DH segments within 35 kb of the C mu gene and identification of a new DH locus. EMBO J (1988) 1.95

Kpn I family of long interspersed repeated DNA sequences in primates: polymorphism of family members and evidence for transcription. Proc Natl Acad Sci U S A (1983) 1.94

Cellular proteins that bind the von Hippel-Lindau disease gene product: mapping of binding domains and the effect of missense mutations. Cancer Res (1995) 1.91

Hereditary papillary renal cell carcinoma. J Urol (1994) 1.87

Novel mutations in FH and expansion of the spectrum of phenotypes expressed in families with hereditary leiomyomatosis and renal cell cancer. J Med Genet (2005) 1.85

Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging. Neurology (2006) 1.83

Biologically active components from mycobacterial cell walls. I. Isolation and composition of cell wall skeleton and component P3. J Natl Cancer Inst (1974) 1.82

Hypomorphic mutations in meckelin (MKS3/TMEM67) cause nephronophthisis with liver fibrosis (NPHP11). J Med Genet (2009) 1.82

Identification of the promoter of the human von Hippel-Lindau disease tumor suppressor gene. Oncogene (1995) 1.82

The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis. Proc Natl Acad Sci U S A (2001) 1.81

Dimensions of the impact of cancer pain in a four country sample: new information from multidimensional scaling. Pain (1996) 1.80

Immunotherapy of cancer: regression of tumors after intralesional injection of living Mycobacterium bovis. Science (1971) 1.80

Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Australia-New Zealand Heart Failure Research Collaborative Group. J Am Coll Cardiol (1997) 1.79

Suppression of murine tumor growth by immune reaction to the Bacillus Calmette-Guérin strain of Mycobacterium bovis. J Natl Cancer Inst (1972) 1.75

Somatic mutations in the kinase domain of the Met/hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas. Cancer Res (1999) 1.74

Tumor cytotoxicity in vitro by macrophages from mice infected with mycobacterium bovis strain BCG. J Natl Cancer Inst (1974) 1.74

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells. J Biol Chem (1996) 1.70

cDNA cloning and characterization of the human interleukin 13 receptor alpha chain. J Biol Chem (1996) 1.68

Early prevention of left ventricular dysfunction after myocardial infarction with angiotensin-converting-enzyme inhibition. Lancet (1991) 1.67

Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B. Proc Natl Acad Sci U S A (2001) 1.67

BCG and cancer. N Engl J Med (1974) 1.66

Determinants of total body and regional bone mineral density in normal postmenopausal women--a key role for fat mass. J Clin Endocrinol Metab (1992) 1.66

Two North American families with hereditary papillary renal carcinoma and identical novel mutations in the MET proto-oncogene. Cancer Res (1998) 1.66

Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene. Proc Natl Acad Sci U S A (2001) 1.65

Mechanism of tumorigenesis of renal carcinomas associated with the constitutional chromosome 3;8 translocation. Cancer J Sci Am (2006) 1.64

Tumor immunity produced by the intradermal inoculation of living tumor cells and living Mycobacterium bovis (strain BCG). Science (1970) 1.64

Endolymphatic sac tumors. A source of morbid hearing loss in von Hippel-Lindau disease. JAMA (1997) 1.63

Perinatal morbidity in chronic hypertension. Br J Obstet Gynaecol (1996) 1.59

Medical supervision of sport diving in Scotland: reassessing the need for routine medical examinations. Br J Sports Med (2000) 1.59

Histopathology of endocervical infection caused by Chlamydia trachomatis, herpes simplex virus, Trichomonas vaginalis, and Neisseria gonorrhoeae. Hum Pathol (1990) 1.58

Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway. Mol Cell Biol (2001) 1.58

Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines. J Lab Clin Med (1992) 1.58

SARCOMA OF THE STOMACH: WITH REPORT OF THREE CASES. Ann Surg (1920) 1.57

Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer. Proc Natl Acad Sci U S A (1992) 1.56

Can we explain why some people do and some people do not act on their intentions? Psychol Health Med (2003) 1.56

Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG. Cancer Res (1996) 1.55

Thrombolysis in acute myocardial infarction: reducing in hospital treatment delay. N Z Med J (1995) 1.55

Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer. J Natl Cancer Inst (2001) 1.55

Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer. Cancer Res (2001) 1.55