Published in Drug Metab Dispos on April 15, 1977
Glutathione S-transferase activities in the yellow-fever mosquito [Aedes aegypti (Louisville)] during growth and aging. Biochem J (1983) 0.90
Metabolic activation/deactivation reactions during perinatal development. Environ Health Perspect (1979) 0.85
Perinatal development of, and effect of chemical pretreatment on, glycine N-acyltransferase activities in liver and kidney of rabbit and rat. Biochem J (1978) 0.77
Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation. J Biol Chem (2000) 3.15
Aryl hydrocarbon receptor-dependent induction of cyp1a1 by bilirubin in mouse hepatoma hepa 1c1c7 cells. Mol Pharmacol (1997) 1.49
Inhibition of glutathione S-transferase zeta and tyrosine metabolism by dichloroacetate: a potential unifying mechanism for its altered biotransformation and toxicity. Biochem Biophys Res Commun (1999) 1.32
Clinical pharmacology and toxicology of dichloroacetate. Environ Health Perspect (1998) 1.32
Pharmacokinetics, metabolism and toxicology of dichloroacetate. Drug Metab Rev (1998) 1.29
Chemical depletion of glutathione in vivo. Methods Enzymol (1981) 1.20
The conjugation of phenylacetic acid in man, sub-human primates and some non-primate species. Proc R Soc Lond B Biol Sci (1972) 1.17
Grapefruit juice-terfenadine single-dose interaction: magnitude, mechanism, and relevance. Clin Pharmacol Ther (1997) 1.16
Grapefruit-felodipine interaction: effect of unprocessed fruit and probable active ingredients. Clin Pharmacol Ther (2000) 1.09
Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1-aminobenzotriazole. J Pharmacol Exp Ther (2000) 1.06
The pulmonary uptake, accumulation, and metabolism of xenobiotics. Annu Rev Pharmacol Toxicol (1985) 1.06
A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit. J Pharmacol Exp Ther (1972) 1.05
In vitro metabolic activation of the pulmonary toxin, 4-ipomeanol, in nonciliated bronchiolar epithelial (Clara) and alveolar type II cells isolated from rabbit lung. J Pharmacol Exp Ther (1982) 1.03
Grapefruit juice-felodipine interaction: effect of naringin and 6',7'-dihydroxybergamottin in humans. Clin Pharmacol Ther (1998) 1.03
Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver. J Pharmacol Exp Ther (1972) 1.03
Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. Clin Pharmacol Ther (1996) 1.02
Grapefruit juice-felodipine interaction: reproducibility and characterization with the extended release drug formulation. Br J Clin Pharmacol (1995) 1.00
Effects of epoxyeicosatrienoic acids on isolated hearts and ventricular myocytes. Am J Physiol (1993) 1.00
Hepatic microsomal mixed-function oxidase activity of several marine species from coastal Maine. Drug Metab Dispos (1975) 0.97
Prostaglandin H synthase and xenobiotic oxidation. Annu Rev Pharmacol Toxicol (1990) 0.96
Defective induction of phenol glucuronidation by 3-methylcholanthrene in Gunn rats is due to the absence of a specific UDP-glucuronosyltransferase isoenzyme. Mol Pharmacol (1987) 0.96
Kinetics and metabolism of chloral hydrate in children: identification of dichloroacetate as a metabolite. Biochem Biophys Res Commun (1997) 0.95
Selective inhibitors of cytochromes P450. Toxicol Appl Pharmacol (1994) 0.95
A general assay for UDPglucuronosyltransferase activity using polar amino-cyano stationary phase HPLC and UDP[U-14C]glucuronic acid. Anal Biochem (1986) 0.94
Metabolism of xenobiotics by the isolated perfused lung. Comparison with in vitro incubations. Drug Metab Dispos (1975) 0.92
Hepatic and extrahepatic metabolism, in vitro, of an epoxide (8-(14) C-styrene oxide) in the rabbit. Biochem Pharmacol (1976) 0.91
Mixed-function oxidases and the alveolar macrophage. Biochem Pharmacol (1972) 0.91
Paraquat uptake into freshly isolated rabbit lung epithelial cells and its reduction to the paraquat radical under anaerobic conditions. Mol Pharmacol (1986) 0.89
Xenobiotic metabolism in Clara cells and alveolar type II cells isolated from lungs of rats treated with beta-naphthoflavone. J Pharmacol Exp Ther (1983) 0.89
Use of mitomycin C with conjunctival autograft in pterygium surgery in Asian-Canadians. Ophthalmology (1999) 0.89
Pulmonary metabolism of xenobiotics. Life Sci (1976) 0.86
Hepatic and extrahepatic metabolism of 14C-styrene oxide. Environ Health Perspect (1976) 0.86
Benzo(a)pyrene metabolism in hepatic microsomes from feral and 3-methycholanthrene-treated southern flounder, Paralichthys lethostigma. J Environ Pathol Toxicol Oncol (1984) 0.86
Conjugation of organic pollutants in aquatic species. Environ Health Perspect (1987) 0.86
Female-predominant expression of testosterone 16 alpha-hydroxylase ("I"-P-450(16)alpha) and its repression in strain 129/J. Arch Biochem Biophys (1986) 0.86
Reliability and reproducibility of a Chinese-language visual function assessment. Ophthalmic Epidemiol (2001) 0.85
Determinants of the renal handling of 2, 4-dichlorophenoxyacetic acid by winter flounder. J Pharmacol Exp Ther (1979) 0.85
Metabolism and biliary excretion of benzo[a]pyrene 4,5-oxide in the rat. Drug Metab Dispos (1980) 0.84
The effect of some biphenyl solubilizing and suspending agents on biphenyl 4-hydroxylase of rabbit liver microsomes. Chem Biol Interact (1973) 0.84
Inhibition of rat liver glutathione S-transferase activity by aprotic solvents. FEBS Lett (1979) 0.84
Polycyclic aromatic hydrocarbon induction of cytochrome P-450-dependent mixed-function oxidases in marine fish. Toxicol Appl Pharmacol (1980) 0.84
The metabolism and excretion of 14C-styrene oxide-glutathione adducts administered to the winter flounder, Pseudopleuronectes americanus, a marine teleost. Identification of the corresponding S-cysteine derivatives as major urinary metabolites. Drug Metab Dispos (1984) 0.84
Epoxide hydrase and glutathione S-transferase activities with selected alkene and adrene oxides in several marine species. Chem Biol Interact (1979) 0.84
Effect of micelle fatty acid composition and 3,4,3', 4'-tetrachlorobiphenyl (TCB) exposure on intestinal [(14)C]-TCB bioavailability and biotransformation in channel catfish in situ preparations. Toxicol Sci (2000) 0.83
Hepatic glutathione transferase activity induced by polycyclic aromatic compounds. Lack of correlation with the murine Ah locus. Mol Pharmacol (1980) 0.83
Modification of benzo(a)pyrene metabolism in hepatic microsomes from untreated and induced rats by imidazole derivatives which inhibit monooxygenase activity and enhance epoxide hydrolase activity. Drug Metab Dispos (1983) 0.83
Determination of ketoconazole in the plasma, liver, lung and adrenal of the rat by high-performance liquid chromatography. J Chromatogr (1986) 0.83
Purification and characterization of hepatic and intestinal phenol sulfotransferase with high affinity for benzo[a]pyrene phenols from channel catfish, Ictalurus punctatus. Arch Biochem Biophys (2000) 0.83
Bioavailability and biotransformation of benzo(a)pyrene in an isolated perfused In situ catfish intestinal preparation. Environ Health Perspect (1998) 0.83
The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol. Mol Pharmacol (1982) 0.83
Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole. Chem Res Toxicol (1997) 0.83
Microsomal cytochrome P450 1A1 dependent monooxygenase activity in guinea pig heart: induction, inhibition, and increased activity by addition of exogenous NADPH-cytochrome P450 reductase. Can J Physiol Pharmacol (1993) 0.82
Inhalation studies with a glycol complex of aluminum-chloride-hydroxide. Arch Environ Health (1974) 0.82
Differential in vivo effects of alpha-naphthoflavone and beta-naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney. J Biochem Mol Toxicol (1999) 0.82
Serum glutathione S-transferases: perinatal development, sex difference, and effect of carbon tetrachloride administration on enzyme activity in the rat. Life Sci (1977) 0.82
Microsomal cytochrome P450 peroxygenase metabolism of arachidonic acid in guinea pig liver. J Pharmacol Exp Ther (1996) 0.82
Distribution of benzo[a]pyrene in pregnant rats following inhalation exposure and a comparison with similar data obtained with pyrene. J Appl Toxicol (1993) 0.82
Cytosolic glutathione S-transferases in various rat tissues differ in stereoselectivity with polycyclic arene and alkene oxide substrates. Drug Metab Dispos (1986) 0.81
Taurine conjugation of 2,4-dichlorophenoxyacetic acid and phenylacetic acid in two marine species. Xenobiotica (1976) 0.81
Detection of glutathione thiyl free radical catalyzed by prostaglandin H synthase present in keratinocytes. Study of co-oxidation in a cellular system. J Biol Chem (1989) 0.81
Determination of dichloroacetate and its metabolites in human plasma by gas chromatography-mass spectrometry. J Chromatogr B Biomed Sci Appl (1997) 0.81
Purification and properties of rat kidney UDP-glucuronosyltransferase. Biochem Pharmacol (1987) 0.81
The metabolism of styrene oxide in the isolated perfused rat liver. Identification and quantitation of major metabolites. Drug Metab Dispos (1977) 0.81
The role of glutathione S-transferases in the hepatic metabolism of benzo[a]pyrene in white suckers (Catostomus commersoni) from polluted and reference sites in the Great Lakes. Comp Biochem Physiol C (1990) 0.81
Cytochrome P-450-dependent oxidation of progesterone, testosterone, and ecdysone in the spiny lobster, Panulirus argus. Arch Biochem Biophys (1984) 0.80
Effects of vitamin A deficiency on hepatic and extrahepatic mixed-function oxidase and epoxide-metabolizing enzymes in guinea pig and rabbit. Biochem Pharmacol (1979) 0.80
Prediction of pulmonary benzo(a)pyrene 4,5-oxide clearance: a pharmacokinetic analysis of epoxide-metabolizing enzymes in rabbit lung. J Pharmacol Exp Ther (1980) 0.80
3-Methylcholanthrene does not induce in vitro xenobiotic metabolism in spiny lobster hepatopancreas, or affect in vivo disposition of benzo[a]pyrene. Comp Biochem Physiol C (1984) 0.80
Stereoselectivity of styrene oxidation in microsomes and in purified cytochrome P-450 enzymes from rat liver. J Pharmacol Exp Ther (1989) 0.80
Carcinogenic effects of 1,2-dibromoethane (ethylene dibromide; EDB) in Japanese medaka (Oryzias latipes). Mutat Res (1998) 0.80
Stereoselectivity and regioselectivity of purified human glutathione transferases pi, alpha-epsilon, and mu with alkene and polycyclic arene oxide substrates. Drug Metab Dispos (1988) 0.80
Biocompatibility of particulate polymethylmethacrylate bone cements: a comparative study in vitro and in vivo. Biomaterials (1992) 0.80
Synthesis and relative stereochemistry of the four mercapturic acids derived from styrene oxide and N-acetylcysteine. Chem Biol Interact (1981) 0.80
Glutathione biosynthesis from sulfur-containing amino acids in enriched populations of Clara and type II cells and macrophages freshly isolated from rabbit lung. J Pharmacol Exp Ther (1987) 0.80
Effects of chlorinated diphenyl ethers on the mixed-function oxidases and ultrastructure of rat and trout liver. Toxicol Appl Pharmacol (1985) 0.80
In vitro metabolism of xenobiotics in some marine animals. Ann N Y Acad Sci (1978) 0.80
Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids. Mol Pharmacol (1994) 0.80
Mechanism controlling the renal excretion of xenobiotics in fish: effects of chemical structure. Drug Metab Rev (1984) 0.79
Polyhalogenated biphenyls and phenobarbital: evaluation as inducers of drug metabolizing enzymes in the sheepshead, Archosargus probatocephalus. Chem Biol Interact (1981) 0.79
Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2 metabolites contribute to the pulmonary vascular hyporeactivity in rats with acute Pseudomonas pneumonia. J Pharmacol Exp Ther (2001) 0.79
Bioavailability, metabolism, and renal excretion of benzoic acid in the channel catfish (Ictalurus punctatus). Drug Metab Dispos (1991) 0.79
Relationship between biotransformation and the toxicity and fate of xenobiotic chemicals in fish. Environ Health Perspect (1980) 0.79
Pulmonary metabolism of epoxides. Fed Proc (1978) 0.79
An oxytetracycline residue depletion study to assess the physiologically based pharmokinetic (PBPK) model in farmed Atlantic salmon. Can Vet J (1997) 0.79
Pharmacokinetics and bioavailability of pyrene in the rat. J Toxicol Environ Health (1991) 0.79
Epoxide-metabolizing enzyme activities and cytochrome P-450 content of rat ovaries during pregnancy. Biochem Biophys Res Commun (1978) 0.79
Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole. J Pharmacol Exp Ther (1985) 0.79
Epoxide metabolizing enzyme activities in rat testes: postnatal development and relative activity in interstitial and spermatogenic cell compartments. Chem Biol Interact (1978) 0.79
Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1. Biochemistry (1997) 0.79