Published in Pediatrics on August 01, 1964
Holoprosencephaly. Orphanet J Rare Dis (2007) 2.63
The "D" (13-15) trisomy syndrome: an analysis of 7 examples. Arch Dis Child (1966) 1.86
Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes. J Clin Invest (2004) 1.74
Holoprosencephaly: a paradigm for the complex genetics of brain development. J Inherit Metab Dis (1998) 1.56
Analysis of genotype-phenotype correlations in human holoprosencephaly. Am J Med Genet C Semin Med Genet (2010) 1.51
Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape. Development (2010) 1.49
A broad range of ophthalmologic anomalies is part of the holoprosencephaly spectrum. Am J Med Genet A (2011) 1.44
Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 7. Alcohol Clin Exp Res (2009) 1.32
Unique organization of the frontonasal ectodermal zone in birds and mammals. Dev Biol (2008) 1.29
Mechanisms that underlie co-variation of the brain and face. Genesis (2011) 1.26
Molecular evaluation of foetuses with holoprosencephaly shows high incidence of microdeletions in the HPE genes. Hum Genet (2005) 1.14
It's all in your head: new insights into craniofacial development and deformation. J Anat (2005) 1.13
Neuroembryology and functional anatomy of craniofacial clefts. Indian J Plast Surg (2009) 1.10
The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse. PLoS One (2014) 1.05
New findings for phenotype-genotype correlations in a large European series of holoprosencephaly cases. J Med Genet (2011) 1.04
Clinical characterization of individuals with deletions of genes in holoprosencephaly pathways by aCGH refines the phenotypic spectrum of HPE. Hum Genet (2010) 1.03
Missense substitutions in the GAS1 protein present in holoprosencephaly patients reduce the affinity for its ligand, SHH. Hum Genet (2011) 0.98
Extreme variability of expression of a Sonic Hedgehog mutation: attention difficulties and holoprosencephaly. Arch Dis Child (2002) 0.98
Cebocephaly, alobar holoprosencephaly, spina bifida, and sirenomelia in a stillbirth. J Med Genet (1997) 0.96
MRI and 1H MRS findings in Smith-Lemli-Opitz syndrome. Neuroradiology (2003) 0.96
Midline "brain in brain": an unusual variant of holoprosencephaly with anterior prosomeric cortical dysplasia. Childs Nerv Syst (2006) 0.96
The unfolding clinical spectrum of holoprosencephaly due to mutations in SHH, ZIC2, SIX3 and TGIF genes. Eur J Hum Genet (2010) 0.95
Cytogenetic findings indicate heterogeneity in patients with blepharophimosis, epicanthus inversus, and developmental delay. J Med Genet (1995) 0.95
Holoprosencephaly: a family showing dominant inheritance and variable expression. J Med Genet (1993) 0.94
The emerging face of primary cilia. Genesis (2011) 0.94
Congenital nasal pyriform aperture stenosis: A rare cause of nasal airway obstruction in a neonate. Indian J Radiol Imaging (2010) 0.90
The teratogenic effects of 5-fluoro-2-desoxyuridine (F.U.D.R.) on the Wistar rat fetus with particular reference to cleft palate. J Anat (1978) 0.89
Facial phenotypes in subgroups of prepubertal boys with autism spectrum disorders are correlated with clinical phenotypes. Mol Autism (2011) 0.89
What is the incidence of holoprosencephaly? J Med Genet (1984) 0.88
Cyclopia: an epidemiologic study in a large dataset from the International Clearinghouse of Birth Defects Surveillance and Research. Am J Med Genet C Semin Med Genet (2011) 0.88
Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans. Wiley Interdiscip Rev Dev Biol (2014) 0.88
Further studies on the genetic heterogeneity of cebocephaly. J Med Genet (1976) 0.87
Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects. PLoS Genet (2012) 0.87
Holoprosencephaly with multiple anomalies of the craniofacial bones-an autopsy report. J Clin Diagn Res (2013) 0.85
The midline craniofacial skeleton in holoprosencephalic fetuses. J Med Genet (1991) 0.84
Relation over time between facial measurements and cognitive outcomes in fetal alcohol-exposed children. Alcohol Clin Exp Res (2012) 0.84
Holoprosencephaly: a guide to diagnosis and clinical management. Indian Pediatr (2011) 0.83
Midline brain-in-brain malformation associated with bilateral perirolandic cortical abnormalities: an image review of this rare disorder. Pediatr Radiol (2012) 0.83
Multiple congenital anomalies associated with a ring-D chromosome. J Med Genet (1969) 0.82
Floor of the median orbit in human cyclopia: an anatomical study in three dimensions. J Anat (1990) 0.81
Links between abnormal brain structure and cognition in holoprosencephaly. Pediatr Neurol (2006) 0.80
Case of true cyclopia. Br J Ophthalmol (1985) 0.79
Apert's syndrome with central nervous system anomalies. Acta Neuropathol (1979) 0.79
Hard to swallow: Developmental biological insights into pediatric dysphagia. Dev Biol (2015) 0.78
Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival. Hum Mol Genet (2014) 0.78
Small optic discs. Br J Ophthalmol (1978) 0.77
Agnathia Holoprosencephaly and Situs Inversus in A Neonate Born to an Alcoholic Mother. J Clin Diagn Res (2015) 0.77
A case of cebocephaly-holoprosencephaly with an aberrant adenohypophysis. Childs Nerv Syst (1987) 0.77
MRI of the fetal eyes: morphologic and biometric assessment for abnormal development with ultrasonographic and clinicopathologic correlation. Pediatr Radiol (2008) 0.77
Forebrain development in fetal MRI: evaluation of anatomical landmarks before gestational week 27. Neuroradiology (2010) 0.76
Holoprosencephaly in an Egyptian baby with ectrodactyly-ectodermal dysplasia-cleft syndrome: a case report. J Med Case Rep (2012) 0.76
The Nervous System Orchestrates and Integrates Craniofacial Development: A Review. Front Physiol (2016) 0.76
If the skull fits: magnetic resonance imaging and microcomputed tomography for combined analysis of brain and skull phenotypes in the mouse. Physiol Genomics (2012) 0.76
Median cerebrofacial dysgenesis. Calif Med (1970) 0.75
The language-ready head: Evolutionary considerations. Psychon Bull Rev (2017) 0.75
Trilobar holoprosencephaly ("triprosencephaly"): a unique type of cerebral malformation. Acta Neuropathol (1995) 0.75
Chromosomal abnormalities associated with cyclopia and synophthalmia. Trans Am Ophthalmol Soc (1977) 0.75
Imaging the fetal central nervous system. Facts Views Vis Obgyn (2011) 0.75
Alobar Holoprosencephaly Associated with Meningomyelocoele and Omphalocoele: An Unusual Coexistence. J Clin Diagn Res (2016) 0.75
Surgical Repair of a Median Cleft of the Upper Lip via a Pfeifer Incision: A Case Report. J Dent (Tehran) (2016) 0.75
Proboscis Lateralis : A Rare Bilateral Case in Association with Holoprosencephaly. J Clin Diagn Res (2015) 0.75
An unusual manifestation of holoprosencephaly in a pig. Can Vet J (1987) 0.75
Prenatal ultrasound diagnosis of holoprosencephaly and associated anomalies. BMJ Case Rep (2012) 0.75
[Holoprosencephaly alobar amid polymalformative syndrome: contribution of imaging in a case report]. Pan Afr Med J (2013) 0.75
Median cleft lip: A new method of surgical repair. Indian J Plast Surg (2010) 0.75
The middle interhemispheric variant of holoprosencephaly: magnetic resonance and diffusion tensor imaging findings. Br J Radiol (2016) 0.75
Exploring the Underlying Genetics of Craniofacial Morphology through Various Sources of Knowledge. Biomed Res Int (2016) 0.75
True cyclopia-very rare anomaly. J Clin Diagn Res (2014) 0.75
Management of Midline Facial Clefts. J Maxillofac Oral Surg (2015) 0.75
Holoprosencephaly: antenatal and postnatal diagnosis and outcome. Childs Nerv Syst (2016) 0.75
Holoprosencephaly in Mexico: first reported autopsy case by Dr. Agustín Arellano. Childs Nerv Syst (2007) 0.75
Accurate diagnosis of prenatal cleft lip/palate by understanding the embryology. World J Methodol (2017) 0.75
[Usefulness and technique of Hortegas silver carbonate method]. Arch Psychiatr Nervenkr Z Gesamte Neurol Psychiatr (1952) 2.24
Painful opthalmoplegia. Its relation to indolent inflammation of the carvernous sinus. Neurology (1961) 2.21
The action of the vincaleukolastine on mitosis in vitro. Exp Cell Res (1960) 2.17
FAMILIAL ALOBAR HOLOPROSENCEPHALY (ARHINENCEPHALY) WITH MEDIAN CLEFT LIP AND PALATE. REPORT OF PATIENT WITH 46 CHROMOSOMES. Neurology (1963) 1.89
Alobar holoprosencephaly (arhinencephaly) with median cleft lip and palate: clinical, electroencephalographic and nosologic considerations. Confin Neurol (1963) 1.89
FINE STRUCTURE OF THE LIPID BODIES IN JUVENILE AMAUROTIC IDIOCY. Acta Neuropathol (1963) 1.70
Idiopathic dystonia musculorum deformans. II. The formes frustes. Neurology (1960) 1.52
PELIZAEUS-MERZBACHER DISEASE. A STUDY IN NOSOLOGY. J Neuropathol Exp Neurol (1964) 1.49
Idiopathic dystonia musculorum deformans. I. The hereditary pattern. Am J Hum Genet (1959) 1.29
Occult endemic encephalitozoonosis of the central nervous system of mice (Swiss-Bagg-O'Grady strain). J Neuropathol Exp Neurol (1962) 1.21
Impregnation of axons and terminal buttons in routine, paraffin, or frozen sections of central and peripheral nervous tissue; adaptation of Hortega's silver carbonate method for neurofibrils. Am J Clin Pathol (1958) 1.11
Histopathologic effect of high-energy-particle microbeams on the visual cortex of the mouse brain. Radiat Res (1961) 1.11
IMPLICATIONS OF GERSTMANN'S SYNDROME. J Neurol Neurosurg Psychiatry (1964) 1.09
The effect of surface active agents on the permeability to dye of the plasma membrane of Ehrlich ascites cells. Exp Cell Res (1960) 1.06
The nonspecific lesions of Hallervorden-Spatz disease; a histochemical study. J Neuropathol Exp Neurol (1958) 1.02
A 46 CHROMOSOME CEBOCEPHALY, WITH REMARKS ON THE RELATION OF 13-15 TRISOMY TO HOLOPROSENCEPHALY (ARHINENCEPHALY). Ann Paediatr (1964) 1.00
Number of axons and myelin sheaths in adult human medullary pyramids; study with silver impregnation and iron hematoxylin staining methods. Neurology (1959) 0.99
DISTURBANCES OF NUCLEIC ACID METABOLISM PRECEDING DELAYED RADIONECROSIS OF NERVOUS TISSUE. Proc Natl Acad Sci U S A (1963) 0.98
The quantitative corticoid origin of pyramidal axons of Macaca rhesus. With some remarks on the slow rate of axolysis. Neurology (1961) 0.95
Radiosensitivities of nervous tissues. Brookhaven Symp Biol (1961) 0.95
Possible use of synthetic surface-active agents for the preparation of tumour cell nuclei. Nature (1958) 0.94
The action of synthetic surfactants on membranes of tumor cells. I. Morphological observations. Exp Cell Res (1961) 0.93
ABERRANT PERIPHERAL NERVE FIBRES IN THE MEDULLA OBLONGATA OF MAN. J Neurol Neurosurg Psychiatry (1965) 0.93
EEG IN HOLOPROSENCEPHALY (ARHINENCEPHALY). Arch Neurol (1964) 0.92
The action of synthetic surfactants on membranes of tumor cells. II. Titration experiments. Exp Cell Res (1961) 0.90
Rabbit heart cell culture, strain RHF-1. I. Growth, cytology, histology, and susceptibility to some inclusion-inducing viruses. J Natl Cancer Inst (1961) 0.90
The number of axons in the right and left medullary pyramids of Macaca rhesus and the ratio of axons to myelin sheaths. Acta Morphol Neerl Scand (1958) 0.88
Juvenile and late forms of amaurotic idiocy in one family. J Neurol Neurosurg Psychiatry (1962) 0.85
Tolerance of mouse-brain tissue to high-energy deuterons. Science (1959) 0.84
Inhibition of Ehrlich ascites tumour growth by surface-active agents. Nature (1960) 0.83
The design and calibration of a deuteron microbeam for biological studies. Radiat Res (1961) 0.83
Tumors of the septum pellucidum and adjacent structures with abnormal affective behavior: an anterior midline structure syndrome. J Nerv Ment Dis (1958) 0.83
Infectivity experiments with nucleic acids of the Shope rabbit papilloma and derived carcinomas. J Natl Cancer Inst (1963) 0.82
The cytology of rabbit papillomas and derived carcinomas. J Natl Cancer Inst (1959) 0.81
Pathologic and behavioral changes in mice after deuteron irradiation of the central nervous system. Radiat Res (1963) 0.79
Clinical considerations in "Schilder's disease". Am J Dis Child (1962) 0.79
Neuronal dye-sorption as a histochemical indicator of nervous activity. Nature (1959) 0.79
VINBLASTINE-INDUCED MALFORMATIONS OF FACE AND NERVOUS SYSTEM IN TWO RAT STRAINS. Neurology (1964) 0.78
UNIQUE ANGIOGRAPHIC AND VENTRICULOGRAPHIC PATTERN OF ALOBAR HOLOPROSENCEPHALY (ARHINENCEPHALY). Radiology (1965) 0.78
AUTOSOMAL INACTIVATION AND SECONDARY CONSTRICTIONS. Lancet (1964) 0.77
HISTOCHEMISTRY OF PARTICLE MICROBEAM LESIONS IN THE BRAIN OF THE MOUSE. J Neuropathol Exp Neurol (1964) 0.77
[Dosage tolerance of cerebral tissue in deep roentgenotherapy]. Strahlentherapie (1950) 0.77
Primary reticuloses of the central nervous system in dogs. Am J Vet Res (1962) 0.77
[RADIATION INJURIES OF THE NERVOUS SYSTEM]. Arch Psychiatr Nervenkr (1964) 0.75
EEG ABNORMALITIES IN EARLY CHILDHOOD SCHIZOPHRENIA: A DOUBLE-BLIND STUDY OF PSYCHIATRICALLY DISTURBED AND NORMAL CHILDREN DURING PROMAZINE SEDATION. Am J Psychiatry (1964) 0.75
A CLINICAL, PATHOLOGICAL, AND GENETIC STUDY OF AN UNUSUAL FORM OF TAY-SACHS DISEASE WITH MACULAR DEGENERATION IN THE FAMILY. J Neurol Neurosurg Psychiatry (1964) 0.75
An unusual case of primary demyelinating disease. J Neuropathol Exp Neurol (1960) 0.75
[Neuropsychiatric syndromes in sarcoidosis]. Dtsch Med Wochenschr (1951) 0.75
CLOSED METOPIC SUTURE WITH TRIGONOCEPHALY IN DOWN'S SYNDROME. Neurology (1965) 0.75
[Not Available]. Dtsch Med Wochenschr (1949) 0.75
Differential dye-uptake in excited and non-excited nervous tissue after treatment with pepsin and neotetrazolium chloride. J Histochem Cytochem (1961) 0.75
LONG-TERM PATHOLOGIC AND BEHAVIORAL CHANGES IN MICE AFTER FOCAL DEUTERON IRRADIATION OF THE BRAIN. Radiat Res (1963) 0.75
[Transverse section syndrome in paramyeloblastosis]. Z Gesamte Inn Med (1951) 0.75
The Radiomicrography of the autopsy brain. I. The normal pattern. Radiology (1955) 0.75
Contribution to the pathogenesis of subacute combined degeneration of the spinal cord; report of two cases. Am J Clin Pathol (1957) 0.75
ON THE NATURE OF THE "STORED" LIPID SUBSTANCES IN JUVENILE AMAUROTIC IDIOCY (BATTEN-SPIELMEYER-VOGT). Ann Histochim (1964) 0.75
[Etiology of cardiovascular dysregulations; poisoning with tinperalcylen]. Dtsch Arch Klin Med (1951) 0.75
The syndrome of complete interruption of the corticospinal tract in the brainstem of man: a case report and comparison with the effects of pyramidotomy in the monkey. Trans Am Neurol Assoc (1959) 0.75
[Problem of injury to cerebral tissue in shock therapy]. Arch Psychiatr Nervenkr Z Gesamte Neurol Psychiatr (1950) 0.75
[Studies on the prophylaxis of experimental allergic encephalomyelitis]. Dtsch Z Nervenheilkd (1958) 0.75
Methods and advantages of random sampling in the census of nerve fibers and other histological elements. Anat Rec (1956) 0.75
[Results with hydergin therapy of arteriosclerotic circulatory disorders]. Dtsch Med Wochenschr (1951) 0.75
[Meningoencephalitis Besnier-Boeck-Schaumann]. Nervenarzt (1952) 0.75
A histopathological study of heterologous transplants of an unusual brain tumor. Cancer Res (1955) 0.75
[Pathology of the torula infection]. Dtsch Z Nervenheilkd (1952) 0.75
THE LEMNISCO-PYRAMIDAL INTERCALARY BUNDLE. A HITHERTO-UNRECOGNIZED BUNDLE OF AXONS LOCATED BETWEEN THE MEDIAL LEMNISCUS AND THE CORTICOSPINAL TRACT IN MACACA RHESUS. Neurology (1963) 0.75
Decortication as a result of widespread circulatory and anoxic damage. J Neuropathol Exp Neurol (1957) 0.75
A COMPARISON OF CYTOLOGIC EFFECTS OF LEUROSINE METHIODIDE AND VINBLASTINE IN THE TISSUE CULTURE. Cancer Chemother Rep (1963) 0.75
Oral procaine amide treatment of Huntington's chorea. Am J Med Sci (1954) 0.75