PubRank

J Harbott

Author PubWeight™ 98.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 New insights to the MLL recombinome of acute leukemias. Leukemia 2009 4.07
2 Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group. Blood 2000 3.13
3 Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000. Leukemia 2009 2.78
4 Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS) Blood 1997 2.40
5 Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by the polymerase chain reaction. Lancet 1991 2.33
6 Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Münster. Leukemia 2000 2.21
7 Myelodysplasia and acute myelogenous leukemia in Down's syndrome. A report of 40 children of the AML-BFM Study Group. Leukemia 1996 1.96
8 The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia. Proc Natl Acad Sci U S A 2001 1.82
9 Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23). Oncogene 1997 1.80
10 Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements. Leukemia 2003 1.64
11 Down's syndrome in childhood acute lymphoblastic leukemia: clinical characteristics and treatment outcome in four consecutive BFM trials. Berlin-Frankfurt-Münster Group. Leukemia 1998 1.44
12 A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells. Oncogene 1999 1.39
13 Prognostic impact of age in children and adolescents with acute lymphoblastic leukemia: data from the trials ALL-BFM 86, 90, and 95. Klin Padiatr 2005 1.32
14 Philadelphia chromosome-positive (Ph+) childhood acute lymphoblastic leukemia: good initial steroid response allows early prediction of a favorable treatment outcome. Blood 1998 1.31
15 Nineteen cases of the t(1;22)(p13;q13) acute megakaryblastic leukaemia of infants/children and a review of 39 cases: report from a t(1;22) study group. Leukemia 2000 1.28
16 Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome. Leukemia 2004 1.21
17 Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML. Leukemia 2008 1.18
18 Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Münster Study Group. Blood 1997 1.16
19 Acute megakaryoblastic leukemia in children and adolescents, excluding Down's syndrome: improved outcome with intensified induction treatment. Leukemia 2005 1.14
20 Mapping of the breakpoints on the short arm of chromosome 17 in neoplasms with an i(17q). Genes Chromosomes Cancer 1999 1.10
21 Phenotypic and genotypic heterogeneity in infant acute leukemia. II. Acute nonlymphoblastic leukemia. Leukemia 1989 1.10
22 TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia. Blood 2000 1.10
23 Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL). A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92. Leukemia 1996 1.10
24 The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q. Proc Natl Acad Sci U S A 2000 1.09
25 Trisomy 21 is a recurrent secondary aberration in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion. Genes Chromosomes Cancer 1999 1.08
26 Detection of four different 11q23 chromosomal abnormalities by multiplex-PCR and fluorescence-based automatic DNA-fragment analysis. Leukemia 1995 1.06
27 ALK fusion genes in children with atypical myeloproliferative leukemia. Leukemia 2010 1.05
28 The translocation t(1;22)(p13;q13) is a nonrandom marker specifically associated with acute megakaryocytic leukemia in young children. Blood 1992 1.04
29 Relapse and clonal disease in children with aplastic anemia (AA) after immunosuppressive therapy (IST): the SAA 94 experience. German/Austrian Pediatric Aplastic Anemia Working Group. Klin Padiatr 1998 1.02
30 Favorable outcome of B-cell acute lymphoblastic leukemia in childhood: a report of three consecutive studies of the BFM group. Blood 1992 1.02
31 The International Prognostic Scoring System (IPSS) for childhood myelodysplastic syndrome (MDS) and juvenile myelomonocytic leukemia (JMML). Leukemia 2004 0.98
32 In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype. Leukemia 2004 0.97
33 Loss of heterozygosity on chromosome 6q14-q24 is associated with poor outcome in children and adolescents with T-cell lymphoblastic lymphoma. Leukemia 2006 0.96
34 Clinical significance of P-glycoprotein expression and function for response to induction chemotherapy, relapse rate and overall survival in acute leukemia. Haematologica 2000 0.95
35 Biology and clinical significance of the TEL/AML1 rearrangement. Curr Opin Pediatr 1999 0.94
36 Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease. German-Austrian Pediatric Hodgkin's Disease Group. J Clin Oncol 1997 0.94
37 Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87. Blood 1995 0.94
38 The T-ALL specific t(11;14)(p13;q11) translocation breakpoint cluster region is located near to the Wilms' tumour predisposition locus. Oncogene 1988 0.93
39 Detection and clinical relevance of genetic abnormalities in pediatric acute lymphoblastic leukemia: a comparison between cytogenetic and polymerase chain reaction analyses. Leukemia 1993 0.92
40 Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7. European Working Group on MDS in Childhood (EWOG-MDS). Leukemia 1999 0.90
41 Expression of the C-kit receptor (CD117) is a feature of almost all subtypes of de novo acute myeloblastic leukemia (AML), including cytogenetically good-risk AML, and lacks prognostic significance. Leuk Lymphoma 1999 0.90
42 The impact of TEL-AML1 (ETV6-RUNX1) expression in precursor B cells and implications for leukaemia using three different genome-wide screening methods. Blood Cancer J 2013 0.90
43 Infant acute lymphoblastic leukemia - combined cytogenetic, immunophenotypical and molecular analysis of 77 cases. Leukemia 2002 0.90
44 Phenotypic and genotypic heterogeneity in infant acute leukemia. I. Acute lymphoblastic leukemia. Leukemia 1989 0.89
45 Multiplex PCR--a rapid screening method for detection of gene rearrangements in childhood acute lymphoblastic leukemia. Ann Hematol 1999 0.89
46 An ins(X;11)(q24;q23) fuses the MLL and the Septin 6/KIAA0128 gene in an infant with AML-M2. Genes Chromosomes Cancer 2001 0.88
47 A non-random chromosome abnormality found in precursor-B lineage acute lymphoblastic leukaemia: dic(9;20)(p1?3;q11). Leukemia 1995 0.87
48 Constitutive expression levels of CD95 and Bcl-2 as well as CD95 function and spontaneous apoptosis in vitro do not predict the response to induction chemotherapy and relapse rate in childhood acute lymphoblastic leukaemia. Br J Haematol 2000 0.86
49 No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities. Leukemia 2005 0.86
50 Tumour karyotype may be important in the prognosis of human neuroblastoma. J Cancer Res Clin Oncol 1986 0.86
51 Key treatment questions in childhood acute lymphoblastic leukemia: results in 5 consecutive trials performed by the ALL-BFM study group from 1981 to 2000. Klin Padiatr 2013 0.86
52 Detection of acute leukemia cells with mixed lineage leukemia (MLL) gene rearrangements by flow cytometry using monoclonal antibody 7.1. Leukemia 2000 0.85
53 Evolution of tumor cytogenetic aberrations and N-myc oncogene amplification in a case of disseminated neuroblastoma. Cancer Genet Cytogenet 1987 0.85
54 Acute myeloid leukemia: analysis of ras gene mutations and clonality defined by polymorphic X-linked loci. Leukemia 1989 0.85
55 Minimal requirements for the diagnosis, classification, and evaluation of the treatment of childhood acute lymphoblastic leukemia (ALL) in the "BFM Family" Cooperative Group. Med Pediatr Oncol 1992 0.85
56 Monitoring of minimal residual disease (MRD) by real-time quantitative reverse transcription PCR (RQ-RT-PCR) in childhood acute myeloid leukemia with AML1/ETO rearrangement. Leukemia 2003 0.84
57 Identification of two distinct MYC breakpoint clusters and their association with various IGH breakpoint regions in the t(8;14) translocations in sporadic Burkitt-lymphoma. Leukemia 2007 0.84
58 Unsupervised proteome analysis of human leukaemia cells identifies the Valosin-containing protein as a putative marker for glucocorticoid resistance. Leukemia 2006 0.83
59 Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission. Blood 1994 0.82
60 Acute leukemia with chromosome translocation (4;11): 7 new patients and analysis of 71 cases. Blut 1987 0.82
61 Blastic phase chronic myeloid leukemia with a four-break rearrangement: t(11;9)(9;22)(q23;p22q34;q11). Cancer Genet Cytogenet 1993 0.81
62 Expression of cell-cell interacting genes distinguishes HLXB9/TEL from MLL-positive childhood acute myeloid leukemia. Leukemia 2010 0.81
63 Cytogenetic findings in acute leukaemias of infants. Br J Cancer Suppl 1992 0.81
64 Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia. Leukemia 2008 0.81
65 Immunophenotype and clinical characteristics of CD45-negative and CD45-positive childhood acute lymphoblastic leukemia. Ann Hematol 1998 0.81
66 Ectopic expression of the HLXB9 gene is associated with an altered nuclear position in t(7;12) leukaemias. Leukemia 2009 0.81
67 t(7;12)(q36;p13), a new recurrent translocation involving ETV6 in infant leukemia. Genes Chromosomes Cancer 2000 0.81
68 Detection of translocations involving the HOX11/TCL3-locus in 10q24 by interphase fluorescence in situ hybridization. Cancer Genet Cytogenet 2001 0.80
69 Cluster analysis of genomic ETV6-RUNX1 (TEL-AML1) fusion sites in childhood acute lymphoblastic leukemia. Leuk Res 2008 0.80
70 Classification of deletions and identification of cryptic translocations involving 7q by fluorescence in situ hybridization (FISH). Leukemia 1996 0.80
71 Lack of expression of the chondroitin sulphate proteoglycan neuron-glial antigen 2 on candidate stem cell populations in paediatric acute myeloid leukaemia/abn(11q23) and acute lymphoblastic leukaemia/t(4;11). Br J Haematol 2006 0.80
72 T-cell acute childhood lymphoblastic leukemia with chromosome 14 q 11 anomaly: a morphologic, immunologic, and cytogenetic analysis of 10 patients. Blut 1988 0.80
73 Impact of CD133 (AC133) and CD90 expression analysis for acute leukemia immunophenotyping. Haematologica 2001 0.79
74 [Concept and interim result of the ALL-BFM 90 therapy study in treatment of acute lymphoblastic leukemia in children and adolescents: the significance of initial therapy response in blood and bone marrow]. Klin Padiatr 1994 0.79
75 Identification of new partner chromosomes involved in fusions with the ETV6 (TEL) gene in hematologic malignancies. Genes Chromosomes Cancer 1998 0.79
76 Fragile sites and neuroblastoma: fragile site at 1p13.1 and other points on lymphocyte chromosomes from patients and family members. Cancer Genet Cytogenet 1988 0.79
77 (11; 14) translocation in three boys with acute lymphoblastic leukemia of T-cell immunophenotype. Blut 1986 0.79
78 A new recurrent translocation, t(5;11)(q35;p15.5), associated with del(5q) in childhood acute myeloid leukemia. The UK Cancer Cytogenetics Group (UKCCG) Blood 1999 0.78
79 Asymmetric multiplex-polymerase chain reaction - a high throughput method for detection and sequencing genomic fusion sites in t(4;11). Br J Haematol 2004 0.78
80 A novel ABL1 fusion to the SH2 containing inositol phosphatase-1 (SHIP1) in acute lymphoblastic leukemia (ALL). Leukemia 2011 0.78
81 Incidence and clinical implications of acute hybrid leukemia in childhood. Haematol Blood Transfus 1990 0.78
82 [Classification of AML by morphologic, immunologic and cytogenetic criteria. Review with reference to subtypes in the AML-BFM-87 study]. Klin Padiatr 1993 0.77
83 In vitro drug resistance profile of Philadelphia positive acute lymphoblastic leukemia is heterogeneous and related to age: a report of the Dutch and German Leukemia Study Groups. Med Pediatr Oncol 2002 0.77
84 Quantification of leukaemic cells based on heteroduplex formation of tal-1 gene sequences after PCR coamplification. Br J Haematol 1993 0.77
85 A new fingerprint method for sequence analysis of chromosomal translocations at the genomic DNA level. Leukemia 1998 0.77
86 The GSTT1 deletion polymorphism is associated with initial response to glucocorticoids in childhood acute lymphoblastic leukemia. Leukemia 2004 0.77
87 Detection of HRX-FEL fusion transcripts in pre-pre-B-ALL with and without cytogenetic demonstration of t(4;11). Leukemia 1994 0.77
88 Double target in situ hybridization applied to the study of numerical aberrations in childhood acute lymphoblastic leukemia. Cancer Genet Cytogenet 1994 0.77
89 Detection of hyperdiploid karyotypes (>50 chromosomes) in childhood acute lymphoblastic leukemia (ALL) using fluorescence in situ hybridization (FISH). Leukemia 1998 0.76
90 Cytogenetic aspects of childhood leukemias. Klin Padiatr 2013 0.76
91 Prognostic significance of eosinophilia in acute myelomonocytic leukemia in relation to induction treatment. Haematol Blood Transfus 1990 0.75
92 Acute myelogenous leukaemia in children under 2 years--experiences of the West German AML studies BFM-78, -83 and -87. AML-BFM Study Group. Br J Cancer Suppl 1992 0.75
93 Low frequency of RAS gene mutations and absence of mutations within the FLR exon of NF1 in patients with therapy-related leukemias. Leukemia 1995 0.75
94 Granulocyte colony-stimulating factor receptor expression and 11q23/MLL genotype in childhood acute lymphoblastic leukemia developing during the first 18 months of life. Leukemia 2000 0.75
95 Comparative genomic hybridization in childhood acute lymphoblastic leukemia: correlation with interphase cytogenetics and loss of heterozygosity analysis. Cancer Genet Cytogenet 2001 0.75
96 A complex translocation in a 5-year-old boy with acute myeloblastic leukemia. Cancer Genet Cytogenet 1986 0.75
97 Karyotypes in acute childhood leukemias may lose prognostic significance with more intensive and specific chemotherapy. Cancer Genet Cytogenet 1991 0.75
98 Acute promyelocytic leukaemia with hypogranular bone marrow blasts in a 16-year-old girl: diagnostic value of different genetic methods. Eur J Pediatr 1995 0.75
99 DNA aneuploidy in childhood acute lymphoblastic leukemia: relation to clinical determinants and prognosis within four consecutive BFM trials. Recent Results Cancer Res 1993 0.75
100 Treatment of relapsed acute myelogeneous leukaemia with MLL/AF 6 fusion after stem cell transplantation by intensive reinduction followed by adoptive immunotherapy. Leukemia 2005 0.75
101 t(5;14)(q33-34;q11), a new recurring cytogenetic abnormality in childhood acute leukemia. Leukemia 1994 0.75
102 Characterization of chromosome 8 abnormalities by fluorescence in situ hybridization in childhood B-acute lymphoblastic leukemia/non-Hodgkin lymphoma. Cancer Genet Cytogenet 1995 0.75
103 [Chromosome aberrations in acute leukemia in childhood: analysis of 1009 patients]. Klin Padiatr 1991 0.75
104 [Biclonal leukemia O-ALL/AMoL) with 11;19 translocation and trisomy X in an 8-month-old girl]. Klin Padiatr 1986 0.75
105 Clinical, morphologic, cytogenetic and prognostic implications of CD34 expression in childhood and adult de novo AML. Leuk Lymphoma 1995 0.75
106 Chromosomal aberrations in childhood acute nonlymphoblastic leukemia. Haematol Blood Transfus 1990 0.75
107 Frequency and DNA sequence of tal-1 rearrangement in children with T-cell acute lymphoblastic leukemia. Ann Hematol 1992 0.75
108 [Prognostic significance of eosinophilia in children with acute myeloid leukemia in the studies AML-BFM-78 and -83]. Klin Padiatr 1989 0.75
109 Incidence and prognostic significance of immunophenotypic subgroups in childhood acute lymphoblastic leukemia: experience of the BFM study 86. Recent Results Cancer Res 1993 0.75
110 Treatment response and residual-disease monitoring in initial and relapsed TEL-AML1 positive childhood ALL. Leukemia 2001 0.75
111 Alteration of blast phenotype after low-dose cytarabine in children with acute myeloid leukemia. Haematol Blood Transfus 1987 0.75
112 Ambiguous phenotypes and genotypes in 16 children with acute leukemia as characterized by multiparameter analysis. Blood 1988 0.75
113 [Specific chromosome aberrations in leukemias and tumors in childhood]. Monatsschr Kinderheilkd 1987 0.75
114 [Detection of aberrations in the karyotype of children with acute leukemia: a comparative analysis of cytogenetics and flow cytophotometry]. Klin Padiatr 1987 0.75
115 12q13, a new recurrent breakpoint in acute non-lymphoblastic leukemia. Cancer Genet Cytogenet 1995 0.75
116 Prognostic meaning of chromosome aberrations in acute lymphocytic leukemia and acute nonlymphocytic leukemia patients of the BFM Study Group. Haematol Blood Transfus 1987 0.75
117 Absence of point mutations within the AML-1 gene in patients with MDS/AML and loss of chromosome 5q or 7. Ann Hematol 2001 0.75
118 Expression of identical E2A/PBX1 fusion transcripts occurs in both pre-B and early pre-B immunological subtypes of childhood acute lymphoblastic leukemia. Leukemia 1993 0.75
119 BCR-ABL rearrangement in a child with acute myelogenous leukaemia without a Philadelphia chromosome. Br J Haematol 1993 0.75
120 [Acute myeloid leukemia in children with Down syndrome]. Klin Padiatr 1995 0.75
121 The prognostic meaning of marker chromosomes in human urinary bladder carcinoma. Prog Clin Biol Res 1984 0.75