Published in BMJ on September 20, 2003
The effects of theophylline on hospital admissions and exacerbations in COPD patients: audit data from the Bavarian disease management program. Dtsch Arztebl Int (2014) 1.17
COPD exacerbations.5: management. Thorax (2006) 1.14
Management and prevention of chronic obstructive pulmonary disease exacerbations: a state of the art review. BMC Med (2009) 1.02
The Saudi Guidelines for the Diagnosis and Management of COPD. Ann Thorac Med (2014) 0.92
Chronic obstructive pulmonary disease: the clinical management of an acute exacerbation. Postgrad Med J (2004) 0.89
Treating COPD with PDE 4 inhibitors. Int J Chron Obstruct Pulmon Dis (2007) 0.83
Chronic obstructive pulmonary disease exacerbations: latest evidence and clinical implications. Ther Adv Chronic Dis (2014) 0.81
Acute lung failure. Semin Respir Crit Care Med (2011) 0.81
Theophylline. Pharmaceuticals (Basel) (2010) 0.78
Treatment of chronic obstructive pulmonary disease in hospitalized geriatric patients. Z Gerontol Geriatr (2014) 0.76
Review: methylxanthines are not effective for acute exacerbations of chronic obstructive pulmonary disease. ACP J Club (2004) 0.75
Management of acute ventilatory failure. Postgrad Med J (2006) 0.75
Doxofylline and theophylline: a comparative clinical study. J Clin Diagn Res (2012) 0.75
Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials (1996) 64.38
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med (2001) 27.83
BTS guidelines for the management of chronic obstructive pulmonary disease. The COPD Guidelines Group of the Standards of Care Committee of the BTS. Thorax (1997) 9.69
Optimal assessment and management of chronic obstructive pulmonary disease (COPD). The European Respiratory Society Task Force. Eur Respir J (1995) 7.03
Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. American Thoracic Society. Am J Respir Crit Care Med (1995) 6.99
Aminophylline therapy for acute bronchospastic disease in the emergency room. Ann Intern Med (1991) 2.51
Evidence base for management of acute exacerbations of chronic obstructive pulmonary disease. Ann Intern Med (2001) 1.88
Comparison of the oral and intravenous routes for treating asthma with methylprednisolone and theophylline. Chest (1988) 1.60
Theophylline serum concentration and therapeutic effect in severe acute bronchial obstruction: the optimal use of intravenously administered aminophylline. Am Rev Respir Dis (1982) 1.18
Theophylline in asthma. N Engl J Med (1996) 1.09
A controlled study of slow-release theophylline and aminophylline in patients with chronic bronchitis. Br J Dis Chest (1982) 1.04
Oral theophylline for chronic obstructive pulmonary disease. Cochrane Database Syst Rev (2002) 1.01
Theophylline target concentration in severe airways obstruction - 10 or 20 mg/L? A randomised concentration-controlled trial. Clin Pharmacokinet (1993) 0.96
Aminophylline for acute exacerbations of chronic obstructive pulmonary disease. A controlled trial. Ann Intern Med (1987) 0.95
Time and theophylline concentration help explain the recovery of peak flow following acute airways obstruction. Population analysis of a randomised concentration controlled trial. Clin Pharmacokinet (1993) 0.95
Therapeutic activities of theophylline in chronic obstructive pulmonary disease. Clin Exp Allergy (1998) 0.93
Theophylline and salbutamol improve pulmonary function in patients with irreversible chronic obstructive pulmonary disease. Chest (1992) 0.92
Intravenous aminophylline in the treatment of acute bronchospastic exacerbations of chronic obstructive pulmonary disease. Ann Emerg Med (1984) 0.89
Effect of three different bronchodilators during an exacerbation of chronic obstructive pulmonary disease. Eur Respir J (1988) 0.85
Comparison of intravenously administered doxofylline and placebo for the treatment of severe acute airways obstruction. J Int Med Res (1988) 0.82
Rapid assay of serum theophylline levels. Ann Emerg Med (1986) 0.81
[Increase of arterial oxygen pressure in therapy with theophylline in patients with obstructive ventilation disorder and partial respiratory insufficiency]. Prax Klin Pneumol (1988) 0.80
[Effects of theophylline on the course of hypercapnic respiratory insufficiency]. Clin Ter (1990) 0.80
Comparative trials including a beta 2 adrenergic agonist, a methylxanthine, and a mast cell stabilizer. Ann Allergy (1988) 0.80
Treatment of respiratory failure due to advanced chronic obstructive lung disease. Arch Intern Med (1980) 0.80
A comparative trial of ipratropium bromide (Atrovent), controlled release theophylline (Phyllocontin), and a combination of these in patients with reversible airflow obstruction. Br J Clin Pract (1986) 0.80
A double-blind comparison of a microcrystalline theophylline tablet and salbutamol in reversible airways obstruction. Br J Clin Pract (1977) 0.79
Clinical trial of Theograd. Br J Clin Pract (1970) 0.79
Comparative study of the effects of intravenous administration of aminophylline, salbutamol and terbutaline in patients suffering from reversible airways obstruction. Curr Med Res Opin (1984) 0.79
[Clinical, functional and therapeutic aspects of chronic bronchitis and emphysema]. Nord Med (1980) 0.79
[The effect of an oral aminophylline compound with protracted activity on respiratory resistance and blood gases in obstructive respiratory diseases (author's transl)]. Arzneimittelforschung (1978) 0.79
Maintenance of bronchodilation in chronic reversible airways obstruction. Comparison between choline theophyllinate and salbutamol. Practitioner (1982) 0.78
Ultrasonography versus computed tomography for suspected nephrolithiasis. N Engl J Med (2014) 11.30
Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004. Arch Intern Med (2009) 6.84
Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev (2009) 6.70
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol (2006) 6.64
Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men. N Engl J Med (2003) 5.95
Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol (2010) 5.55
Body-mass index and symptoms of gastroesophageal reflux in women. N Engl J Med (2006) 5.24
Outpatient oral prednisone after emergency treatment of chronic obstructive pulmonary disease. N Engl J Med (2003) 5.12
Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med (2009) 4.93
Effects of exercise on breast cancer patients and survivors: a systematic review and meta-analysis. CMAJ (2006) 4.79
The Canadian C-spine rule versus the NEXUS low-risk criteria in patients with trauma. N Engl J Med (2003) 4.48
Activated injectable vitamin D and hemodialysis survival: a historical cohort study. J Am Soc Nephrol (2005) 4.44
Comparison of the Canadian CT Head Rule and the New Orleans Criteria in patients with minor head injury. JAMA (2005) 4.35
Increased US emergency department visits for skin and soft tissue infections, and changes in antibiotic choices, during the emergence of community-associated methicillin-resistant Staphylococcus aureus. Ann Emerg Med (2008) 3.88
The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study. Am J Cardiol (2005) 3.85
Clinical trial: comparative effectiveness of cephalexin plus trimethoprim-sulfamethoxazole versus cephalexin alone for treatment of uncomplicated cellulitis: a randomized controlled trial. Clin Infect Dis (2013) 3.78
A conceptual model of emergency department crowding. Ann Emerg Med (2003) 3.52
Second symposium on the definition and management of anaphylaxis: summary report--second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. Ann Emerg Med (2006) 3.00
Serum 25-hydroxyvitamin D levels among US children aged 1 to 11 years: do children need more vitamin D? Pediatrics (2009) 2.99
Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report. J Allergy Clin Immunol (2010) 2.98
Impact of activated vitamin D and race on survival among hemodialysis patients. J Am Soc Nephrol (2008) 2.96
Cardiac resynchronization therapy for patients with left ventricular systolic dysfunction: a systematic review. JAMA (2007) 2.93
Prospective multicenter study of viral etiology and hospital length of stay in children with severe bronchiolitis. Arch Pediatr Adolesc Med (2012) 2.87
Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group. Ann Allergy Asthma Immunol (2006) 2.85
Implementation of the Canadian C-Spine Rule: prospective 12 centre cluster randomised trial. BMJ (2009) 2.58
Overreliance on symptom quality in diagnosing dizziness: results of a multicenter survey of emergency physicians. Mayo Clin Proc (2007) 2.58
Amino-terminal pro-brain natriuretic peptide for the diagnosis of acute heart failure in patients with previous obstructive airway disease. Ann Emerg Med (2006) 2.57
Vitamin D insufficiency in pregnant and nonpregnant women of childbearing age in the United States. Am J Obstet Gynecol (2010) 2.54
Symposium on the definition and management of anaphylaxis: summary report. J Allergy Clin Immunol (2005) 2.54
A controlled trial to increase detection and treatment of osteoporosis in older patients with a wrist fracture. Ann Intern Med (2004) 2.48
Multicenter study of repeat epinephrine treatments for food-related anaphylaxis. Pediatrics (2010) 2.45
Use of proton pump inhibitors and risk of hip fracture in relation to dietary and lifestyle factors: a prospective cohort study. BMJ (2012) 2.45
Variation in management of recent-onset atrial fibrillation and flutter among academic hospital emergency departments. Ann Emerg Med (2010) 2.44
Increasing United States hospital admissions for acute pancreatitis, 1988-2003. Ann Epidemiol (2007) 2.39
Exercise interventions for upper-limb dysfunction due to breast cancer treatment. Cochrane Database Syst Rev (2010) 2.35
Low plasma level of cathelicidin antimicrobial peptide (hCAP18) predicts increased infectious disease mortality in patients undergoing hemodialysis. Clin Infect Dis (2009) 2.34
Physical inactivity and idiopathic pulmonary embolism in women: prospective study. BMJ (2011) 2.34
Validation of ICD-9-CM coding algorithm for improved identification of hypoglycemia visits. BMC Endocr Disord (2008) 2.31
Direct medical costs of syncope-related hospitalizations in the United States. Am J Cardiol (2005) 2.30
Replacement of oral corticosteroids with inhaled corticosteroids in the treatment of acute asthma following emergency department discharge: a meta-analysis. Chest (2002) 2.28
Positive association between altitude and suicide in 2584 U.S. counties. High Alt Med Biol (2011) 2.28
Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial. JAMA (2012) 2.27
The accuracy of the enzyme-linked immunosorbent assay D-dimer test in the diagnosis of pulmonary embolism: a meta-analysis. Ann Emerg Med (2002) 2.25
Spectrum of dizziness visits to US emergency departments: cross-sectional analysis from a nationally representative sample. Mayo Clin Proc (2008) 2.25
The relation between hyperglycemia and outcomes in 2,471 patients admitted to the hospital with community-acquired pneumonia. Diabetes Care (2005) 2.24
A meta-analysis of asthma and risk of lung cancer (United States). Cancer Causes Control (2003) 2.24
Validation of self-reported chronic obstructive pulmonary disease in a cohort study of nurses. Am J Epidemiol (2002) 2.24
Association between prehospital vitamin D status and hospital-acquired bloodstream infections. Am J Clin Nutr (2013) 2.21
National study of US emergency department visits for attempted suicide and self-inflicted injury, 1997-2001. Ann Emerg Med (2005) 2.20
Access to emergency care in the United States. Ann Emerg Med (2009) 2.19
Availability of rapid human immunodeficiency virus testing in academic emergency departments. Acad Emerg Med (2008) 2.17
Characteristics and admission patterns of patients presenting with syncope to U.S. emergency departments, 1992-2000. Acad Emerg Med (2004) 2.15
Evaluation of pulmonary embolism in the emergency department and consistency with a national quality measure: quantifying the opportunity for improvement. Arch Intern Med (2012) 2.15
Trends in bronchiolitis hospitalizations in the United States, 2000-2009. Pediatrics (2013) 2.14
Asthma exacerbations in North American adults: who are the "frequent fliers" in the emergency department? Chest (2005) 2.10
Cigarette smoking among asthmatic adults presenting to 64 emergency departments. Chest (2003) 2.09
Frequency of leisure-time physical activity and serum 25-hydroxyvitamin D levels in the US population: results from the Third National Health and Nutrition Examination Survey. Am J Epidemiol (2008) 2.08
Population aging and emergency departments: visits will not increase, lengths-of-stay and hospitalizations will. Health Aff (Millwood) (2013) 2.01
Trends in U.S. emergency department visits for mental health conditions, 1992 to 2001. Psychiatr Serv (2005) 2.00
Prospective study of serum 25-hydroxyvitamin D level, cardiovascular disease mortality, and all-cause mortality in older U.S. adults. J Am Geriatr Soc (2009) 1.98
Chronic obstructive pulmonary disease, asthma, and risk of type 2 diabetes in women. Diabetes Care (2004) 1.98
The relationship between obesity and asthma severity and control in adults. J Allergy Clin Immunol (2008) 1.96
Trends and disparities in U.S. emergency department visits for hypoglycemia, 1993-2005. Diabetes Care (2007) 1.96
Canadian Thoracic Society 2012 guideline update: diagnosis and management of asthma in preschoolers, children and adults. Can Respir J (2012) 1.96
Factors associated with positive D-dimer results in patients evaluated for pulmonary embolism. Acad Emerg Med (2010) 1.95
Alcohol drinking patterns and risk of type 2 diabetes mellitus among younger women. Arch Intern Med (2003) 1.95
Predictors of initiation of alcohol use among US adolescents: findings from a prospective cohort study. Arch Pediatr Adolesc Med (2007) 1.94
Increasing critical care admissions from U.S. emergency departments, 2001-2009. Crit Care Med (2013) 1.94
Vitamin D deficiency in pregnancy and gestational diabetes mellitus. Am J Obstet Gynecol (2012) 1.93
Emergency triage: comparing a novel computer triage program with standard triage. Acad Emerg Med (2005) 1.91
Variation in institutional review board responses to a standard, observational, pediatric research protocol. Acad Emerg Med (2007) 1.91
Review Article: The Role of Molecular Pathological Epidemiology in the Study of Neoplastic and Non-neoplastic Diseases in the Era of Precision Medicine. Epidemiology (2016) 1.89
Randomized controlled trial of emergency department interventions to improve primary care follow-up for patients with acute asthma. Chest (2006) 1.87
Parenteral metoclopramide for acute migraine: meta-analysis of randomised controlled trials. BMJ (2004) 1.83
US emergency department visits for alcohol-related diseases and injuries between 1992 and 2000. Arch Intern Med (2004) 1.82
Antibiotic treatment of acute respiratory infections in acute care settings. Acad Emerg Med (2006) 1.82
Emergency department management of acute exacerbations of chronic obstructive pulmonary disease in the elderly: the Multicenter Airway Research Collaboration. J Am Geriatr Soc (2003) 1.81
Pneumococcal pneumonia: potential for diagnosis through a urinary metabolic profile. J Proteome Res (2009) 1.78
Depression following traumatic spinal cord injury. Neuroepidemiology (2005) 1.76
Asthma outcomes: exacerbations. J Allergy Clin Immunol (2012) 1.76
Air pollution and emergency department visits for cardiac and respiratory conditions: a multi-city time-series analysis. Environ Health (2009) 1.76
Increasing length of stay among adult visits to U.S. Emergency departments, 2001-2005. Acad Emerg Med (2009) 1.75
Sexual orientation, gender, and alcohol use in a cohort study of U.S. adolescent girls and boys. Drug Alcohol Depend (2006) 1.75
Characteristics of U.S. emergency departments that offer routine human immunodeficiency virus screening. Acad Emerg Med (2012) 1.72
Perinatal predictors of atopic dermatitis occurring in the first six months of life. Pediatrics (2004) 1.72
Direct medical costs of acute pancreatitis hospitalizations in the United States. Pancreas (2007) 1.71
Trends in US emergency department visits for attempted suicide and self-inflicted injury, 1993-2008. Gen Hosp Psychiatry (2012) 1.71
The Psychiatric Emergency Research Collaboration-01: methods and results. Gen Hosp Psychiatry (2009) 1.71
Key indicators of overcrowding in Canadian emergency departments: a Delphi study. CJEM (2007) 1.70
National study of emergency department visits for sepsis, 1992 to 2001. Ann Emerg Med (2006) 1.69
A survey to determine the prevalence and characteristics of training in Evidence-Based Medicine in emergency medicine residency programs. J Emerg Med (2005) 1.69
Prospective study of vitamin D status at initiation of care in critically ill surgical patients and risk of 90-day mortality. Crit Care Med (2014) 1.67
Vitamin D, respiratory infections, and asthma. Curr Allergy Asthma Rep (2009) 1.66
Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma. Cochrane Database Syst Rev (2013) 1.65
The safety of emergency care systems: Results of a survey of clinicians in 65 US emergency departments. Ann Emerg Med (2008) 1.65
Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review. Allergy Asthma Proc (2007) 1.62
Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma. Cochrane Database Syst Rev (2012) 1.60