Published in Endocrinology on September 18, 2003
Vascular calcification: pathobiology of a multifaceted disease. Circulation (2008) 3.64
Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease. Endocr Rev (2007) 2.82
Control of RANKL gene expression. Bone (2009) 1.47
MyD88 but not TRIF is essential for osteoclastogenesis induced by lipopolysaccharide, diacyl lipopeptide, and IL-1alpha. J Exp Med (2004) 1.36
Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption. Am J Pathol (2005) 1.26
Alendronate treatment of the brtl osteogenesis imperfecta mouse improves femoral geometry and load response before fracture but decreases predicted material properties and has detrimental effects on osteoblasts and bone formation. J Bone Miner Res (2009) 1.21
Eph receptors and ephrin signaling pathways: a role in bone homeostasis. Int J Med Sci (2008) 1.17
Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice. Bone (2011) 1.06
Central IL-1 receptor signaling regulates bone growth and mass. Proc Natl Acad Sci U S A (2005) 1.04
Oxidative stress and gamma radiation-induced cancellous bone loss with musculoskeletal disuse. J Appl Physiol (1985) (2009) 1.03
Osteoprotegerin abrogated cortical porosity and bone marrow fibrosis in a mouse model of constitutive activation of the PTH/PTHrP receptor. Am J Pathol (2009) 1.03
Bone turnover and bone collagen maturation in osteoporosis: effects of antiresorptive therapies. Osteoporos Int (2007) 1.00
The roles of lipid oxidation products and receptor activator of nuclear factor-κB signaling in atherosclerotic calcification. Circ Res (2011) 0.96
The pathogenesis of vascular calcification in the chronic kidney disease mineral bone disorder: the links between bone and the vasculature. Semin Nephrol (2009) 0.96
Expression and synthesis of bone morphogenetic proteins by osteoclasts: a possible path to anabolic bone remodeling. J Histochem Cytochem (2008) 0.95
Stimulation of bone formation in cortical bone of mice treated with a receptor activator of nuclear factor-κB ligand (RANKL)-binding peptide that possesses osteoclastogenesis inhibitory activity. J Biol Chem (2013) 0.94
Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density. Proteomics (2008) 0.94
A histological assessment on the distribution of the osteocytic lacunar canalicular system using silver staining. J Bone Miner Metab (2007) 0.93
Cholesterol in vascular and valvular calcification. Circulation (2001) 0.92
The RANKL inhibitor OPG-Fc increases cortical and trabecular bone mass in young gonad-intact cynomolgus monkeys. Osteoporos Int (2007) 0.89
Alendronate treatment promotes bone formation with a less anisotropic microstructure during intramembranous ossification in rats. J Bone Miner Metab (2008) 0.87
Icariin Augments Bone Formation and Reverses the Phenotypes of Osteoprotegerin-Deficient Mice through the Activation of Wnt/ β -Catenin-BMP Signaling. Evid Based Complement Alternat Med (2013) 0.86
The expression of osteoprotegerin is required for maintaining the intervertebral disc endplate of aged mice. Bone (2011) 0.82
Serum N-Terminal Propeptide of Collagen Type I is Associated with the Number of Bone Metastases in Breast and Prostate Cancer and Correlates to Other Bone Related Markers. Biomark Cancer (2011) 0.81
Impact of recipient-related factors on structural dysfunction of xenoaortic bioprosthetic heart valves. Patient Prefer Adherence (2015) 0.81
Chondrocytes-Specific Expression of Osteoprotegerin Modulates Osteoclast Formation in Metaphyseal Bone. Sci Rep (2015) 0.81
Immobilized-OPG-Fc on a titanium surface inhibits RANKL-dependent osteoclast differentiation in vitro. J Mater Sci Mater Med (2009) 0.78
Influence of exercise on bone remodeling-related hormones and cytokines in ovariectomized rats: a model of postmenopausal osteoporosis. PLoS One (2014) 0.78
Effects of drug discontinuation after short-term daily alendronate administration on osteoblasts and osteocytes in mice. Histochem Cell Biol (2016) 0.78
The effect of risedronate treatment on serum cytokines in postmenopausal osteoporosis: a 6-month randomized and controlled study. J Bone Miner Metab (2009) 0.77
The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts. J Bone Miner Metab (2015) 0.77
OPG rs2073617 polymorphism is associated with upregulated OPG protein expression and an increased risk of intervertebral disc degeneration. Exp Ther Med (2016) 0.77
Zoledronate reverses mandibular bone loss in osteoprotegerin-deficient mice. Osteoporos Int (2008) 0.76
Effects of the bisphosphonate risedronate on osteopenia in OASIS-deficient mice. J Bone Miner Metab (2009) 0.76
The Time Course Changes in Bone Metabolic Markers after Administering the Anti-Receptor Activator of Nuclear Factor-Kappa B Ligand Antibody and Drug Compliance among Patients with Osteoporosis. Asian Spine J (2015) 0.75
Localization of Minodronate in Mouse Femora Through Isotope Microscopy. J Histochem Cytochem (2016) 0.75
Auricular ossification: A newly recognized feature of osteoprotegerin-deficiency juvenile Paget disease. Am J Med Genet A (2016) 0.75
Treatment of OPG-deficient mice with WP9QY, a RANKL-binding peptide, recovers alveolar bone loss by suppressing osteoclastogenesis and enhancing osteoblastogenesis. PLoS One (2017) 0.75
Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays. Genome Res (2006) 5.97
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell (2007) 4.71
Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis. Nat Med (2012) 3.46
Image classification of idiopathic spinal cord herniation based on symptom severity and surgical outcome: a multicenter study. J Neurosurg Spine (2009) 1.98
Success rate of endodontic treatment of teeth with vital and nonvital pulps. A meta-analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2004) 1.96
The 2001 revised criteria for diagnosis, classification, and staging of idiopathic osteonecrosis of the femoral head. J Orthop Sci (2002) 1.84
Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis. Genes Cells (2002) 1.80
Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function. Arthritis Res Ther (2005) 1.79
Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy. J Am Coll Cardiol (2004) 1.79
Minimum 10-year followup after en bloc cervical laminoplasty. Clin Orthop Relat Res (2003) 1.79
Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads. Mol Biol Cell (2003) 1.78
Adjacent segment disease after anterior cervical interbody fusion. Spine J (2004) 1.75
Lineage-committed osteoclast precursors circulate in blood and settle down into bone. J Bone Miner Res (2011) 1.74
Prevalence and distribution of sarcomeric gene mutations in Japanese patients with familial hypertrophic cardiomyopathy. Circ J (2011) 1.64
Characteristic radiographic or magnetic resonance images of fresh osteoporotic vertebral fractures predicting potential risk for nonunion: a prospective multicenter study. Spine (Phila Pa 1976) (2011) 1.63
Clinical outcome and survival after palliative surgery for spinal metastases: palliative surgery in spinal metastases. Cancer (2003) 1.59
Chest wall deformity associated with osteochondroma of the scapula: a case report and review of the literature. J Shoulder Elbow Surg (2005) 1.57
p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function. Endocrinology (2002) 1.52
Low hepatic cytochrome P450 3A activity is a risk for corticosteroid-induced osteonecrosis. Clin Pharmacol Ther (2006) 1.51
Function of OPG as a traffic regulator for RANKL is crucial for controlled osteoclastogenesis. J Bone Miner Res (2010) 1.47
Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2. J Biol Chem (2006) 1.45
The murine glucagon-like peptide-1 receptor is essential for control of bone resorption. Endocrinology (2007) 1.45
Central control of fever and female body temperature by RANKL/RANK. Nature (2009) 1.42
Comparison of surgical outcomes between macro discectomy and micro discectomy for lumbar disc herniation: a prospective randomized study with surgery performed by the same spine surgeon. J Spinal Disord Tech (2006) 1.38
Action of RANKL and OPG for osteoclastogenesis. Crit Rev Eukaryot Gene Expr (2009) 1.37
MyD88 but not TRIF is essential for osteoclastogenesis induced by lipopolysaccharide, diacyl lipopeptide, and IL-1alpha. J Exp Med (2004) 1.36
IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL. Eur J Immunol (2005) 1.34
Soft synthesis of single-crystal silicon monolayer sheets. Angew Chem Int Ed Engl (2006) 1.32
Comparative roles of Twist-1 and Id1 in transcriptional regulation by BMP signaling. J Cell Sci (2007) 1.32
A novel stem cell source for vasculogenesis in ischemia: subfraction of side population cells from dental pulp. Stem Cells (2008) 1.32
Hypoxia-inducible factor regulates survival of antigen receptor-driven T cells. J Immunol (2003) 1.31
Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss. J Bone Miner Res (2009) 1.31
Objective assessment of reduced invasiveness in MED. Compared with conventional one-level laminotomy. Eur Spine J (2005) 1.30
Lipopolysaccharide promotes the survival of osteoclasts via Toll-like receptor 4, but cytokine production of osteoclasts in response to lipopolysaccharide is different from that of macrophages. J Immunol (2003) 1.29
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Dev Growth Differ (2005) 1.28
Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis. Arthritis Rheum (2006) 1.28
Loss of adherence ability to human gingival epithelial cells in S-layer protein-deficient mutants of Tannerella forsythensis. Microbiology (2007) 1.27
Complete pulp regeneration after pulpectomy by transplantation of CD105+ stem cells with stromal cell-derived factor-1. Tissue Eng Part A (2011) 1.27
Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach. Arthritis Res Ther (2006) 1.27
Comparative analysis of gene expression profiles in intact and damaged regions of human osteoarthritic cartilage. Arthritis Rheum (2006) 1.27
Comparison of the percutaneous screw placement precision of isocentric C-arm 3-dimensional fluoroscopy-navigated pedicle screw implantation and conventional fluoroscopy method with minimally invasive surgery. J Spinal Disord Tech (2009) 1.24
Generation of tendon-to-bone interface "enthesis" with use of recombinant BMP-2 in a rabbit model. J Orthop Res (2007) 1.20
Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion. Mol Endocrinol (2006) 1.19
Vertebral reconstruction with biodegradable calcium phosphate cement in the treatment of osteoporotic vertebral compression fracture using instrumentation. J Spinal Disord Tech (2004) 1.18
Surgical outcome of ossification of the posterior longitudinal ligament (OPLL) of the thoracic spine: implication of the type of ossification and surgical options. J Spinal Disord Tech (2005) 1.18
The efficacy and safety of blonanserin compared with haloperidol in acute-phase schizophrenia: a randomized, double-blind, placebo-controlled, multicentre study. CNS Drugs (2009) 1.18
Guidelines on the management and treatment of glucocorticoid-induced osteoporosis of the Japanese Society for Bone and Mineral Research (2004). J Bone Miner Metab (2005) 1.17
Prevalence and risk factors of knee osteoarthritis in Huang-Pu District, Shanghai, China. Rheumatol Int (2004) 1.17
Segmental pedicle screwing for idiopathic scoliosis using computer-assisted surgery. J Spinal Disord Tech (2008) 1.16
The molecular mechanism of osteoclastogenesis in rheumatoid arthritis. Arthritis Res (2002) 1.16
Transplantation of marrow-derived mesenchymal stem cells and platelet-rich plasma during distraction osteogenesis--a preliminary result of three cases. Bone (2004) 1.16
IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-alpha antibody: a novel mechanism of osteoclastogenesis by IL-17. J Cell Biochem (2009) 1.16
Regeneration of dental pulp after pulpotomy by transplantation of CD31(-)/CD146(-) side population cells from a canine tooth. Regen Med (2009) 1.15
Identification of cell cycle-arrested quiescent osteoclast precursors in vivo. J Cell Biol (2009) 1.15
Suppression of osteoprotegerin expression by prostaglandin E2 is crucially involved in lipopolysaccharide-induced osteoclast formation. J Immunol (2004) 1.15
Blonanserin for schizophrenia: systematic review and meta-analysis of double-blind, randomized, controlled trials. J Psychiatr Res (2012) 1.15
Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals. Front Biosci (Landmark Ed) (2011) 1.14
Palsy of the C5 nerve root after midsagittal-splitting laminoplasty of the cervical spine. Spine (Phila Pa 1976) (2003) 1.13
A potential role of 15-deoxy-delta(12,14)-prostaglandin J2 for induction of human articular chondrocyte apoptosis in arthritis. J Biol Chem (2004) 1.13
Osteocytic osteolysis observed in rats to which parathyroid hormone was continuously administered. J Bone Miner Metab (2004) 1.13
Capillary vessel network integration by inserting a vascular pedicle enhances bone formation in tissue-engineered bone using interconnected porous hydroxyapatite ceramics. Tissue Eng (2004) 1.13
Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAK1. J Biol Chem (2005) 1.12
Calcitonin gene-related peptide (CGRP)-containing nerve fibers in bone tissue and their involvement in bone remodeling. Microsc Res Tech (2002) 1.12
Hip-spine syndrome: total sagittal alignment of the spine and clinical symptoms in patients with bilateral congenital hip dislocation. Spine (Phila Pa 1976) (2004) 1.12
Generating murine osteoclasts from bone marrow. Methods Mol Med (2003) 1.11
Carbon nanotubes with high bone-tissue compatibility and bone-formation acceleration effects. Small (2008) 1.11
Separation of the outer membrane and identification of major outer membrane proteins from Porphyromonas gingivalis. Eur J Oral Sci (2002) 1.10
Increased detection rate of Strongyloides stercoralis by repeated stool examinations using the agar plate culture method. Am J Trop Med Hyg (2007) 1.10
A new biotechnology for articular cartilage repair: subchondral implantation of a composite of interconnected porous hydroxyapatite, synthetic polymer (PLA-PEG), and bone morphogenetic protein-2 (rhBMP-2). Osteoarthritis Cartilage (2005) 1.09
Role of the glucocorticoid receptor for regulation of hypoxia-dependent gene expression. J Biol Chem (2003) 1.08
p38 Mitogen-activated protein kinase is crucially involved in osteoclast differentiation but not in cytokine production, phagocytosis, or dendritic cell differentiation of bone marrow macrophages. Endocrinology (2003) 1.08
Secretion of L-glutamate from osteoclasts through transcytosis. EMBO J (2006) 1.07
Water-soluble C60 fullerene prevents degeneration of articular cartilage in osteoarthritis via down-regulation of chondrocyte catabolic activity and inhibition of cartilage degeneration during disease development. Arthritis Rheum (2007) 1.06
Reducing the risk of infection in the elderly by dietary intake of yoghurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1. Br J Nutr (2010) 1.06
Surgical complications and management of occipitothoracic fusion for cervical destructive lesions in RA patients. J Spinal Disord Tech (2010) 1.06
Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone. J Bone Miner Res (2012) 1.06
Efficacy and tolerability of once-weekly administration of 17.5 mg risedronate in Japanese patients with involutional osteoporosis: a comparison with 2.5-mg once-daily dosage regimen. J Bone Miner Metab (2006) 1.06
Hypoxia upregulates the expression of angiopoietin-like-4 in human articular chondrocytes: role of angiopoietin-like-4 in the expression of matrix metalloproteinases and cartilage degradation. J Orthop Res (2009) 1.05
Clinical problems after initial unplanned resection of sarcoma. Jpn J Clin Oncol (2008) 1.05