Published in Structure on October 01, 2003
The death domain superfamily in intracellular signaling of apoptosis and inflammation. Annu Rev Immunol (2007) 3.59
The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. J Biol Chem (2005) 2.21
BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses. PLoS Pathog (2015) 0.89
Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly. J Biol Chem (2014) 0.86
The PYRIN domain in signal transduction. Curr Protein Pept Sci (2007) 0.85
NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain. Structure (2003) 2.15
A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins. J Mol Biol (2003) 2.97
Structural basis for recognition of diubiquitins by NEMO. Mol Cell (2009) 2.73
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer. J Biol Chem (2012) 2.31
Membrane-bound alpha-synuclein forms an extended helix: long-distance pulsed ESR measurements using vesicles, bicelles, and rodlike micelles. J Am Chem Soc (2008) 2.11
Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy. Biophys J (2006) 2.05
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein. J Biol Chem (2008) 1.94
Identification of a copper-binding metallothionein in pathogenic mycobacteria. Nat Chem Biol (2008) 1.90
Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein. Biochemistry (2004) 1.71
Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein. Curr Protein Pept Sci (2009) 1.66
The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states. Biochemistry (2007) 1.63
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. J Neurosci (2010) 1.46
Inter-helix distances in lysophospholipid micelle-bound alpha-synuclein from pulsed ESR measurements. J Am Chem Soc (2006) 1.44
Residual structure, backbone dynamics, and interactions within the synuclein family. J Mol Biol (2007) 1.43
Helix periodicity, topology, and dynamics of membrane-associated alpha-synuclein. Protein Sci (2005) 1.41
The lipid-binding domain of wild type and mutant alpha-synuclein: compactness and interconversion between the broken and extended helix forms. J Biol Chem (2010) 1.39
Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation. Proc Natl Acad Sci U S A (2010) 1.37
Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein. J Biol Chem (2012) 1.13
Charge neutralization and collapse of the C-terminal tail of alpha-synuclein at low pH. Protein Sci (2009) 1.12
In support of the BMRB. Nat Struct Mol Biol (2012) 1.09
Synaptic vesicles position complexin to block spontaneous fusion. Neuron (2013) 1.08
Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat. Structure (2006) 1.08
Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125. J Am Chem Soc (2012) 1.06
Folding and misfolding of alpha-synuclein on membranes. Biochim Biophys Acta (2011) 1.06
E46K Parkinson's-linked mutation enhances C-terminal-to-N-terminal contacts in alpha-synuclein. J Mol Biol (2009) 1.05
Secondary structure and dynamics of micelle bound beta- and gamma-synuclein. Protein Sci (2006) 1.04
STARD4 abundance regulates sterol transport and sensing. Mol Biol Cell (2011) 1.03
c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease. Hum Mol Genet (2014) 1.03
Structural effects of Parkinson's disease linked DJ-1 mutations. Protein Sci (2008) 1.02
NMR mapping of copper binding sites in alpha-synuclein. Biochim Biophys Acta (2005) 1.01
N-terminal acetylation stabilizes N-terminal helicity in lipid- and micelle-bound α-synuclein and increases its affinity for physiological membranes. J Biol Chem (2013) 0.97
Folding of the repeat domain of tau upon binding to lipid surfaces. J Mol Biol (2006) 0.94
The unfolded state of the C-terminal domain of the ribosomal protein L9 contains both native and non-native structure. Biochemistry (2009) 0.93
Biophysics: proteins hunt and gather. Nature (2007) 0.89
The low-pH unfolded state of the C-terminal domain of the ribosomal protein L9 contains significant secondary structure in the absence of denaturant but is no more compact than the low-pH urea unfolded state. Biochemistry (2008) 0.87
The cold denatured state of the C-terminal domain of protein L9 is compact and contains both native and non-native structure. J Am Chem Soc (2010) 0.85
Assigning backbone NMR resonances for full length tau isoforms: efficient compromise between manual assignments and reduced dimensionality. PLoS One (2012) 0.82
Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein. Biochim Biophys Acta (2012) 0.82
Structural transitions in tau k18 on micelle binding suggest a hierarchy in the efficacy of individual microtubule-binding repeats in filament nucleation. Protein Sci (2013) 0.81
Native chemical ligation in covalent caspase inhibition by p35. Chem Biol (2006) 0.80
Structural characterization of two alternate conformations in a calbindin D₉k-based molecular switch. Biochemistry (2011) 0.78
¹H, ¹³C, and ¹⁵N backbone resonance assignments of the L124D mutant of StAR-related lipid transfer domain protein 4 (StARD4). Biomol NMR Assign (2012) 0.77