Published in Nat Struct Biol on October 05, 2003
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Unusual water-mediated antigenic recognition of the proinflammatory cytokine interleukin-18. J Biol Chem (2009) 0.85
Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project. BMC Med Genet (2009) 0.84
Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain. J Neuroimmunol (2009) 0.83
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A (99m)Tc-labeled dual-domain cytokine ligand for imaging of inflammation. Nucl Med Biol (2011) 0.81
Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death. J Mol Cell Cardiol (2014) 0.81
Yaba monkey tumor virus encodes a functional inhibitor of interleukin-18. J Virol (2007) 0.79
Interleukin-12 to interleukin 'infinity': the rationale for future therapeutic cytokine targeting. Springer Semin Immunopathol (2006) 0.78
Purification, crystallization and preliminary X-ray crystallographic analysis of human IL-18 and its extracellular complexes. Acta Crystallogr F Struct Biol Commun (2014) 0.76
Crystallization of interleukin-18 for structure-based inhibitor design. Acta Crystallogr F Struct Biol Commun (2015) 0.75
The inflammasome as a target of modulation by DNA viruses. Future Virol (2013) 0.75
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Immunodeficiency in Two Female Patients with Incontinentia Pigmenti with Heterozygous NEMO Mutation Diagnosed by LPS Unresponsiveness. J Clin Immunol (2017) 0.75
Increased adipose tissue expression of IL-18R and its ligand IL-18 associates with inflammation and insulin resistance in obesity. Immun Inflamm Dis (2017) 0.75
Molluscum contagiosum prevents progression of staphylococcal scalded skin syndrome. Eur J Pediatr (2005) 0.75
Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity (2006) 4.75
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism. Nature (2008) 3.62
Two major Smad pathways in TGF-beta superfamily signalling. Genes Cells (2002) 2.85
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain. EMBO Rep (2009) 2.50
14-3-3 proteins act as intracellular receptors for rice Hd3a florigen. Nature (2011) 2.20
Glomus tumor of the kidney. Int J Urol (2010) 2.12
Crystal structure of thymine DNA glycosylase conjugated to SUMO-1. Nature (2005) 2.11
High-resolution multi-dimensional NMR spectroscopy of proteins in human cells. Nature (2009) 2.06
Structure of the UBA domain of Dsk2p in complex with ubiquitin molecular determinants for ubiquitin recognition. Structure (2005) 1.90
Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development. Proc Natl Acad Sci U S A (2006) 1.77
Protein structure determination in living cells by in-cell NMR spectroscopy. Nature (2009) 1.71
Insights into equilibrium dynamics of proteins from comparison of NMR and X-ray data with computational predictions. Structure (2007) 1.66
Autoantibodies and cell-mediated autoimmunity to NMDA-type GluRepsilon2 in patients with Rasmussen's encephalitis and chronic progressive epilepsia partialis continua. Epilepsia (2005) 1.65
Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling. Proc Natl Acad Sci U S A (2009) 1.65
Sorafenib rechallenge in patients with metastatic renal cell carcinoma. BJU Int (2012) 1.52
Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9. Mol Endocrinol (2004) 1.47
T cell protein tyrosine phosphatase deficiency results in spontaneous synovitis and subchondral bone resorption in mice. Arthritis Rheum (2012) 1.46
Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains. Genes Cells (2004) 1.45
Proton magnetic resonance spectroscopy in a case of subacute sclerosing panencephalitis. J Child Neurol (2002) 1.44
Ablation of the Sam68 RNA binding protein protects mice from age-related bone loss. PLoS Genet (2005) 1.44
Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM. J Biol Chem (2002) 1.41
Structure of the ubiquitin-interacting motif of S5a bound to the ubiquitin-like domain of HR23B. J Biol Chem (2003) 1.40
Skeletal affinity of Tc(V)-DMS is bone cell mediated and pH dependent. Eur J Nucl Med Mol Imaging (2003) 1.40
Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle. Mol Cell Biol (2005) 1.37
Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency. Proc Natl Acad Sci U S A (2009) 1.37
Propranolol for intractable diffuse lymphangiomatosis. N Engl J Med (2011) 1.32
Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis. Cancer Res (2012) 1.23
Roles of anti-hemagglutinin IgA and IgG antibodies in different sites of the respiratory tract of vaccinated mice in preventing lethal influenza pneumonia. Vaccine (2003) 1.23
Structure of the small ubiquitin-like modifier (SUMO)-interacting motif of MBD1-containing chromatin-associated factor 1 bound to SUMO-3. J Biol Chem (2008) 1.23
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function. Biochemistry (2007) 1.22
Intracellular phosphate serves as a signal for the regulation of the PHO pathway in Saccharomyces cerevisiae. J Biol Chem (2004) 1.22
Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1. Proc Natl Acad Sci U S A (2012) 1.22
Paramagnetic relaxation-based 19f MRI probe to detect protease activity. J Am Chem Soc (2007) 1.21
Methylated DNA-binding domain 1 and methylpurine-DNA glycosylase link transcriptional repression and DNA repair in chromatin. Proc Natl Acad Sci U S A (2003) 1.21
STXBP1 mutations in early infantile epileptic encephalopathy with suppression-burst pattern. Epilepsia (2010) 1.19
Propranolol as an alternative treatment option for pediatric lymphatic malformation. Tohoku J Exp Med (2013) 1.19
Plc1p, Arg82p, and Kcs1p, enzymes involved in inositol pyrophosphate synthesis, are essential for phosphate regulation and polyphosphate accumulation in Saccharomyces cerevisiae. J Biol Chem (2005) 1.18
Reduced expression of ubiquitin ligase FBXW7 mRNA is associated with poor prognosis in breast cancer patients. Cancer Sci (2010) 1.18
Development and testing of new screening method for keratan sulfate in mucopolysaccharidosis IVA. Pediatr Res (2004) 1.16
Self-assembling nanoprobes that display off/on 19F nuclear magnetic resonance signals for protein detection and imaging. Nat Chem (2009) 1.16
Reduced expression of the breast cancer metastasis suppressor 1 mRNA is correlated with poor progress in breast cancer. Clin Cancer Res (2006) 1.13
Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6). J Biol Chem (2013) 1.12
Analysis of genetic and predisposing factors in Japanese patients with atypical hemolytic uremic syndrome. Mol Immunol (2013) 1.10
In-cell NMR spectroscopy of proteins inside Xenopus laevis oocytes. J Biomol NMR (2006) 1.10
Defining the pathway for Tat-mediated delivery of beta-glucuronidase in cultured cells and MPS VII mice. Mol Ther (2005) 1.10
Crystal structure of SUMO-3-modified thymine-DNA glycosylase. J Mol Biol (2006) 1.09
Menopausal status should be taken into consideration for patients with luminal a breast cancer in terms of the effect of differential biology on prognosis. J Clin Oncol (2013) 1.09
Autosomal-dominant chronic mucocutaneous candidiasis with STAT1-mutation can be complicated with chronic active hepatitis and hypothyroidism. J Clin Immunol (2012) 1.08
Mouse model of N-acetylgalactosamine-6-sulfate sulfatase deficiency (Galns-/-) produced by targeted disruption of the gene defective in Morquio A disease. Hum Mol Genet (2003) 1.08
A PEX6-defective peroxisomal biogenesis disorder with severe phenotype in an infant, versus mild phenotype resembling Usher syndrome in the affected parents. Am J Hum Genet (2002) 1.07
Reduced hydraulic permeability of three-dimensional collagen scaffolds attenuates gel contraction and promotes the growth and differentiation of mesenchymal stem cells. Acta Biomater (2010) 1.06
Severe form of encephalopathy associated with 2009 pandemic influenza A (H1N1) in Japan. J Clin Virol (2012) 1.06
Solution structure of the fibronectin type III domain from Bacillus circulans WL-12 chitinase A1. J Biol Chem (2001) 1.06
The DNA methyltransferase Dnmt1 directly interacts with the SET and RING finger-associated (SRA) domain of the multifunctional protein Uhrf1 to facilitate accession of the catalytic center to hemi-methylated DNA. J Biol Chem (2013) 1.05
Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin. J Biol Chem (2011) 1.04
Estrogen receptor alpha gene ESR1 amplification may predict endocrine therapy responsiveness in breast cancer patients. Cancer Sci (2009) 1.04
Structure of human PRL-3, the phosphatase associated with cancer metastasis. FEBS Lett (2004) 1.02
Toll-like receptor signaling is impaired in dendritic cells from patients with X-linked agammaglobulinemia. Clin Immunol (2008) 1.02
Real-time background-free selective imaging of fluorescent nanodiamonds in vivo. Nano Lett (2012) 1.02
A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1. J Biol Chem (2001) 1.02
MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain. Nucleic Acids Res (2004) 1.01
Dual-function probe to detect protease activity for fluorescence measurement and 19F MRI. Angew Chem Int Ed Engl (2009) 1.01
Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates. J Biol Chem (2004) 1.01
Autosomal dominant anhidrotic ectodermal dysplasia with immunodeficiency caused by a novel NFKBIA mutation, p.Ser36Tyr, presents with mild ectodermal dysplasia and non-infectious systemic inflammation. J Clin Immunol (2013) 1.00
Early sensitization to house dust mite is a major risk factor for subsequent development of bronchial asthma in Japanese infants with atopic dermatitis: results of a 4-year followup study. Ann Allergy Asthma Immunol (2002) 1.00
Identification of a new complementation group of the peroxisome biogenesis disorders and PEX14 as the mutated gene. Hum Mutat (2004) 1.00
Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN. J Biol Chem (2002) 0.99
Clinicopathological analyses of triple negative breast cancer using surveillance data from the Registration Committee of the Japanese Breast Cancer Society. Breast Cancer (2009) 0.99
Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4. J Biol Chem (2013) 0.99
Midkine in plasma as a novel breast cancer marker. Cancer Sci (2009) 0.98
Japanese guideline for food allergy. Allergol Int (2011) 0.98
Production of MPS VII mouse (Gus(tm(hE540A x mE536A)Sly)) doubly tolerant to human and mouse beta-glucuronidase. Hum Mol Genet (2003) 0.97
Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling. J Biol Chem (2004) 0.97
Japanese guideline for atopic dermatitis. Allergol Int (2011) 0.96
Autoantigenicity of DFS70 is restricted to the conformational epitope of C-terminal alpha-helical domain. J Autoimmun (2004) 0.96
Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable the identification of key residues for binding to replicative helicase Mcm proteins. J Biol Chem (2010) 0.96
Molecular basis for SUMOylation-dependent regulation of DNA binding activity of heat shock factor 2. J Biol Chem (2008) 0.96
The structure of the third intracellular loop of the muscarinic acetylcholine receptor M2 subtype. FEBS Lett (2005) 0.95
Two-metal ion, Ni(II) and Cu(II), binding alpha-helical coiled coil peptide. J Am Chem Soc (2004) 0.95
Loss of BRCA1 expression may predict shorter time-to-progression in metastatic breast cancer patients treated with taxanes. Anticancer Res (2006) 0.95
Structural characterization of the MIT domain from human Vps4b. Biochem Biophys Res Commun (2005) 0.95
Additive antitumor effects of gefitinib and imatinib on anaplastic thyroid cancer cells. Cancer Chemother Pharmacol (2006) 0.95
Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45. Proteins (2010) 0.94
Mitochondrial acetoacetyl-CoA thiolase (T2) deficiency: T2-deficient patients with "mild" mutation(s) were previously misinterpreted as normal by the coupled assay with tiglyl-CoA. Pediatr Res (2004) 0.94
Analysis and comparison of Radix Glycyrrhizae (licorice) from Europe and China by capillary-zone electrophoresis (CZE). J Pharm Biomed Anal (2005) 0.94
Development of a rhenium-186-labeled MAG3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals. Bioconjug Chem (2005) 0.94
Clinical relevance of Ki67 gene expression analysis using formalin-fixed paraffin-embedded breast cancer specimens. Breast Cancer (2012) 0.94
Cell cycle-dependent turnover of 5-hydroxymethyl cytosine in mouse embryonic stem cells. PLoS One (2013) 0.94
Evaluation of ADL in patients with Hunter disease using FIM score. Brain Dev (2007) 0.93
High resolution crystal structures of human cytosolic thiolase (CT): a comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I. J Mol Biol (2005) 0.93