PRT1 of Arabidopsis is a ubiquitin protein ligase of the plant N-end rule pathway with specificity for aromatic amino-terminal residues.

PubWeight™: 1.05‹?› | Rank: Top 15%

🔗 View Article (PMC 281630)

Published in Plant Physiol on October 09, 2003

Authors

Susanne Stary1, Xiao-jun Yin, Thomas Potuschak, Peter Schlögelhofer, Victoria Nizhynska, Andreas Bachmair

Author Affiliations

1: Institute of Botany, University of Vienna, Rennweg 14, A-1030 Vienna, Austria.

Articles citing this

Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis. Plant Physiol (2005) 3.01

A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons. Mol Cell Biol (2005) 2.57

The N-end rule pathway. Annu Rev Biochem (2012) 1.88

The N-end rule pathway: emerging functions and molecular principles of substrate recognition. Nat Rev Mol Cell Biol (2011) 1.62

Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway. J Biol Chem (2008) 1.50

The N-end rule pathway promotes seed germination and establishment through removal of ABA sensitivity in Arabidopsis. Proc Natl Acad Sci U S A (2009) 1.44

The substrate recognition domains of the N-end rule pathway. J Biol Chem (2008) 1.31

The e3 ubiquitin ligase gene family in plants: regulation by degradation. Curr Genomics (2006) 1.29

The N-end rule pathway controls multiple functions during Arabidopsis shoot and leaf development. Proc Natl Acad Sci U S A (2009) 1.13

Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Plant Physiol (2009) 1.10

The ubiquitin-proteasome system regulates the accumulation of Turnip yellow mosaic virus RNA-dependent RNA polymerase during viral infection. Plant Cell (2010) 1.08

Plant oxygen sensing is mediated by the N-end rule pathway: a milestone in plant anaerobiosis. Plant Cell (2011) 1.06

ORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases. Plant J (2008) 1.00

The ubiquitination machinery of the ubiquitin system. Arabidopsis Book (2014) 0.93

Expression of the ubiquitin variant ubR48 decreases proteolytic activity in Arabidopsis and induces cell death. Planta (2005) 0.80

The UBR-box and its relationship to binuclear RING-like treble clef zinc fingers. Biol Direct (2015) 0.78

Phenotypes on demand via switchable target protein degradation in multicellular organisms. Nat Commun (2016) 0.76

Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis. Genes Dev (2017) 0.75

Plant arginyltransferases (ATEs). Genet Mol Biol (2017) 0.75

Articles cited by this

The ubiquitin system. Annu Rev Biochem (1998) 43.36

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene (1988) 42.65

Mechanisms underlying ubiquitination. Annu Rev Biochem (2001) 18.87

In vivo half-life of a protein is a function of its amino-terminal residue. Science (1986) 13.44

Themes and variations on ubiquitylation. Nat Rev Mol Cell Biol (2001) 8.68

A proteolytic pathway that recognizes ubiquitin as a degradation signal. J Biol Chem (1995) 7.79

RING finger proteins: mediators of ubiquitin ligase activity. Cell (2000) 7.75

The N-end rule: functions, mysteries, uses. Proc Natl Acad Sci U S A (1996) 6.51

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell (1999) 6.04

The recognition component of the N-end rule pathway. EMBO J (1990) 4.55

N-terminal acetyltransferases and sequence requirements for N-terminal acetylation of eukaryotic proteins. J Mol Biol (2003) 3.87

Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J (2000) 3.46

Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae. Gene (1983) 3.25

Polyubiquitination of p53 by a ubiquitin ligase activity of p300. Science (2003) 3.21

N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families. Trends Biochem Sci (1998) 3.14

An essential role of N-terminal arginylation in cardiovascular development. Science (2002) 3.06

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature (2001) 3.04

Ubiquitin as a degradation signal. EMBO J (1992) 2.73

The ubiquitin/26S proteasome pathway, the complex last chapter in the life of many plant proteins. Trends Plant Sci (2003) 2.57

Physical association of ubiquitin ligases and the 26S proteasome. Proc Natl Acad Sci U S A (2000) 2.27

ZZ and TAZ: new putative zinc fingers in dystrophin and other proteins. Trends Biochem Sci (1996) 1.94

Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature (2000) 1.90

Ubiquitylation in plants: a post-genomic look at a post-translational modification. Trends Plant Sci (2001) 1.73

The mouse and human genes encoding the recognition component of the N-end rule pathway. Proc Natl Acad Sci U S A (1998) 1.72

Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway. Mol Cell Biol (2000) 1.64

Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway. Mol Cell Biol (2001) 1.54

Using ubiquitin to follow the metabolic fate of a protein. Proc Natl Acad Sci U S A (1996) 1.43

PRT1 of Arabidopsis thaliana encodes a component of the plant N-end rule pathway. Proc Natl Acad Sci U S A (1998) 1.34

Inhibition of the N-end rule pathway in living cells. Proc Natl Acad Sci U S A (1991) 1.31

The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta. Mol Cell Biol (2002) 1.30

A delayed leaf senescence mutant is defective in arginyl-tRNA:protein arginyltransferase, a component of the N-end rule pathway in Arabidopsis. Plant J (2002) 1.28

A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway. J Biol Chem (1996) 1.16

Ubiquitin fusion technique and its descendants. Methods Enzymol (2000) 1.13

Engineering in vivo instability of firefly luciferase and Escherichia coli beta-glucuronidase in higher plants using recognition elements from the ubiquitin pathway. Plant Mol Biol (1998) 0.94

Use of a reporter transgene to generate arabidopsis mutants in ubiquitin-dependent protein degradation. Proc Natl Acad Sci U S A (1993) 0.89

Ca2+-calmodulin binds to the carboxyl-terminal domain of dystrophin. J Biol Chem (1996) 0.86

Articles by these authors

Arabidopsis TCP20 links regulation of growth and cell division control pathways. Proc Natl Acad Sci U S A (2005) 2.40

F-box proteins everywhere. Curr Opin Plant Biol (2006) 1.99

Chromosomal map of the model legume Lotus japonicus. Genetics (2002) 1.60

Interaction between the bHLH transcription factor FIT and ETHYLENE INSENSITIVE3/ETHYLENE INSENSITIVE3-LIKE1 reveals molecular linkage between the regulation of iron acquisition and ethylene signaling in Arabidopsis. Plant Cell (2011) 1.48

A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene. EMBO J (2007) 1.46

The N-end rule pathway promotes seed germination and establishment through removal of ABA sensitivity in Arabidopsis. Proc Natl Acad Sci U S A (2009) 1.44

Have a break: determinants of meiotic DNA double strand break (DSB) formation and processing in plants. J Exp Bot (2011) 1.35

The interplay of RecA-related proteins and the MND1-HOP2 complex during meiosis in Arabidopsis thaliana. PLoS Genet (2007) 1.32

Ubiquitin lysine 63 chain forming ligases regulate apical dominance in Arabidopsis. Plant Cell (2007) 1.30

Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics (2005) 1.29

Sufficient amounts of functional HOP2/MND1 complex promote interhomolog DNA repair but are dispensable for intersister DNA repair during meiosis in Arabidopsis. Plant Cell (2013) 1.21

Lysine63-linked ubiquitylation of PIN2 auxin carrier protein governs hormonally controlled adaptation of Arabidopsis root growth. Proc Natl Acad Sci U S A (2012) 1.19

The Arabidopsis thaliana F-box protein FBL17 is essential for progression through the second mitosis during pollen development. PLoS One (2009) 1.18

Repression of the floral transition via histone H2B monoubiquitination. Plant J (2008) 1.15

A genetic linkage map of the model legume Lotus japonicus and strategies for fast mapping of new loci. Genetics (2002) 1.12

Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Plant Physiol (2009) 1.10

The recombinases DMC1 and RAD51 are functionally and spatially separated during meiosis in Arabidopsis. Plant Cell (2012) 1.09

PRT6/At5g02310 encodes an Arabidopsis ubiquitin ligase of the N-end rule pathway with arginine specificity and is not the CER3 locus. FEBS Lett (2007) 1.09

SUMO conjugation in plants. Planta (2004) 1.07

The Arabidopsis thaliana MND1 homologue plays a key role in meiotic homologous pairing, synapsis and recombination. J Cell Sci (2006) 1.04

The Arabidopsis SWR1 chromatin-remodeling complex is important for DNA repair, somatic recombination, and meiosis. Plant Cell (2013) 0.89

Update on sumoylation: defining core components of the plant SUMO conjugation system by phylogenetic comparison. New Phytol (2012) 0.88

Lotus burttii takes a position of the third corner in the lotus molecular genetics triangle. DNA Res (2005) 0.88

Preferential up-regulation of G2/M phase-specific genes by overexpression of the hyperactive form of NtmybA2 lacking its negative regulation domain in tobacco BY-2 cells. Plant Physiol (2009) 0.83

Elevated salicylic acid levels conferred by increased expression of ISOCHORISMATE SYNTHASE 1 contribute to hyperaccumulation of SUMO1 conjugates in the Arabidopsis mutant early in short days 4. Plant J (2014) 0.83

Distinct roles for Arabidopsis SUMO protease ESD4 and its closest homolog ELS1. Planta (2010) 0.83

A novel ATM-dependent X-ray-inducible gene is essential for both plant meiosis and gametogenesis. Plant J (2009) 0.80

Virus-like particle formation and translational start site choice of the plant retrotransposon Tto1. Virology (2008) 0.80

Expression of the ubiquitin variant ubR48 decreases proteolytic activity in Arabidopsis and induces cell death. Planta (2005) 0.80

Unorthodox mRNA start site to extend the highly structured leader of retrotransposon Tto1 mRNA increases transposition rate. RNA (2005) 0.80

Deletion analysis of the 3' long terminal repeat sequence of plant retrotransposon Tto1 identifies 125 base pairs redundancy as sufficient for first strand transfer. Virology (2011) 0.79

A synthetic biology approach allows inducible retrotransposition in whole plants. Syst Synth Biol (2010) 0.79

Small ubiquitin-like modifier conjugating enzyme with active site mutation acts as dominant negative inhibitor of SUMO conjugation in arabidopsis(F). J Integr Plant Biol (2013) 0.78

Structural and evolutionary analysis of the transcribed sequence of Boudicca, a Schistosoma mansoni retrotransposon. Gene (2004) 0.77

The upstream Sal repeat-containing segment of Arabidopsis thaliana ribosomal DNA intergenic region (IGR) enhances the activity of adjacent protein-coding genes. Plant Mol Biol (2002) 0.76

Retinoblastoma protein goes green: the role of RBR in Arabidopsis meiosis. EMBO J (2011) 0.76

Benefit-of-doubt (BOD) scoring: a sequencing-based method for SNP candidate assessment from high to medium read number data sets. Genomics (2012) 0.75

Varshavsky's contributions. Science (2004) 0.75

A single recessive mutation in the proteolytic machinery of Arabidopsis chloroplasts impairs photoprotection and photosynthesis upon cold stress. Planta (2003) 0.75

Correction to "Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1". J Proteome Res (2016) 0.75