Published in J Clin Endocrinol Metab on October 01, 2003
A consensus on the diagnosis and treatment of acromegaly complications. Pituitary (2013) 1.26
Growth hormone tumor histological subtypes predict response to surgical and medical therapy. Endocrine (2014) 1.09
The multimodal management of GH-secreting pituitary adenomas: predictive factors, strategies and outcomes. J Med Life (2016) 0.75
A case of an acromegalic patient resistant to the recommended maximum GH receptor antagonist dosage. Hippokratia (2012) 0.75
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet (2004) 8.77
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron (2003) 6.05
Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med (2008) 4.85
Activation of p53 by MEG3 non-coding RNA. J Biol Chem (2007) 3.07
The effects of growth hormone on body composition and physical performance in recreational athletes: a randomized trial. Ann Intern Med (2010) 2.99
Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1). J Clin Endocrinol Metab (2012) 2.87
A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells. J Clin Endocrinol Metab (2003) 2.68
Absence of ghrelin protects against early-onset obesity. J Clin Invest (2005) 2.53
MEG3 noncoding RNA: a tumor suppressor. J Mol Endocrinol (2012) 2.41
Increased bone marrow fat in anorexia nervosa. J Clin Endocrinol Metab (2009) 2.31
Uncoupling of cardiovascular risk markers in adolescent girls with anorexia nervosa. J Pediatr (2006) 2.06
Elevated peptide YY levels in adolescent girls with anorexia nervosa. J Clin Endocrinol Metab (2005) 2.03
Acromegaly: an endocrine society clinical practice guideline. J Clin Endocrinol Metab (2014) 2.01
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes. J Neurochem (2006) 2.00
Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men. J Clin Endocrinol Metab (2008) 1.96
Vertebral bone marrow fat is positively associated with visceral fat and inversely associated with IGF-1 in obese women. Obesity (Silver Spring) (2010) 1.93
Acyl and total ghrelin are suppressed strongly by ingested proteins, weakly by lipids, and biphasically by carbohydrates. J Clin Endocrinol Metab (2008) 1.87
Which patients do not require a GH stimulation test for the diagnosis of adult GH deficiency? J Clin Endocrinol Metab (2002) 1.86
Measurement of free testosterone in normal women and women with androgen deficiency: comparison of methods. J Clin Endocrinol Metab (2004) 1.81
Visceral fat is a negative predictor of bone density measures in obese adolescent girls. J Clin Endocrinol Metab (2010) 1.80
Pituitary tumor-transforming gene: physiology and implications for tumorigenesis. Endocr Rev (2007) 1.79
Evidence for extrathyroidal formation of 3-iodothyronamine in humans as provided by a novel monoclonal antibody-based chemiluminescent serum immunoassay. J Clin Endocrinol Metab (2011) 1.79
Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: isoform structure, expression, and functions. Endocrinology (2009) 1.78
A critical appraisal of the prevalence and metabolic significance of brown adipose tissue in adult humans. Am J Physiol Endocrinol Metab (2010) 1.78
Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. Cancer Res (2010) 1.76
Effects of risedronate and low-dose transdermal testosterone on bone mineral density in women with anorexia nervosa: a randomized, placebo-controlled study. J Clin Endocrinol Metab (2011) 1.74
Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab (2006) 1.73
Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls. Pediatrics (2004) 1.73
Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models. Growth Horm IGF Res (2008) 1.72
Medical findings in outpatients with anorexia nervosa. Arch Intern Med (2005) 1.69
Fear conditioning and extinction: influence of sex and menstrual cycle in healthy humans. Behav Neurosci (2006) 1.68
Fracture risk and areal bone mineral density in adolescent females with anorexia nervosa. Int J Eat Disord (2014) 1.64
Bone, fat, and body composition: evolving concepts in the pathogenesis of osteoporosis. Am J Med (2009) 1.63
Effects of once-weekly sustained-release growth hormone: a double-blind, placebo-controlled study in adult growth hormone deficiency. J Clin Endocrinol Metab (2011) 1.62
Marrow fat and bone--new perspectives. J Clin Endocrinol Metab (2013) 1.60
High-sensitivity chemiluminescence immunoassays for detection of growth hormone doping in sports. Clin Chem (2009) 1.60
Quality of life, self-esteem, fatigue, and sexual function in young men after cancer: a controlled cross-sectional study. Cancer (2010) 1.59
Abnormal bone mineral accrual in adolescent girls with anorexia nervosa. J Clin Endocrinol Metab (2002) 1.58
Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11β-hydroxylase inhibitor metyrapone. Ann Clin Biochem (2011) 1.57
Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody. Structure (2012) 1.57
Intermuscular adipose tissue-free skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in adults. J Appl Physiol (1985) (2004) 1.57
FGF21 and the late adaptive response to starvation in humans. J Clin Invest (2015) 1.55
Estrogen regulation of growth hormone action. Endocr Rev (2004) 1.54
Estradiol modulates medial prefrontal cortex and amygdala activity during fear extinction in women and female rats. Biol Psychiatry (2011) 1.51
Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes. FEBS Lett (2008) 1.51
Plasma lipids and osteoporosis in postmenopausal women. Endocr J (2002) 1.51
Angiogenesis in endocrine tumors. Endocr Rev (2003) 1.50
EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas. J Clin Invest (2011) 1.49
Alterations in growth hormone secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism. J Clin Endocrinol Metab (2003) 1.49
High prevalence of brown adipose tissue in adult humans. J Clin Endocrinol Metab (2011) 1.49
Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. J Clin Endocrinol Metab (2002) 1.48
Transsphenoidal surgery for pituitary tumors in the United States, 1996-2000: mortality, morbidity, and the effects of hospital and surgeon volume. J Clin Endocrinol Metab (2003) 1.44
Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells. Endocrinology (2006) 1.43
Secretory dynamics of ghrelin in adolescent girls with anorexia nervosa and healthy adolescents. Am J Physiol Endocrinol Metab (2005) 1.43
Lower growth hormone and higher cortisol are associated with greater visceral adiposity, intramyocellular lipids, and insulin resistance in overweight girls. Am J Physiol Endocrinol Metab (2008) 1.41
Inducible brown adipogenesis of supraclavicular fat in adult humans. Endocrinology (2011) 1.41
Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis. Mol Endocrinol (2005) 1.40
Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance. Diabetes (2007) 1.36
The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects. Eur J Endocrinol (2013) 1.36
Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O(6)-methylguanine methyltransferase (MGMT) promoter methylation and expression. J Clin Endocrinol Metab (2010) 1.34
Brown adipose tissue in adult humans: a metabolic renaissance. Endocr Rev (2013) 1.34
Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. J Clin Endocrinol Metab (2005) 1.34
Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients. J Clin Endocrinol Metab (2011) 1.34
Secretory dynamics of leptin in adolescent girls with anorexia nervosa and healthy adolescents. Am J Physiol Endocrinol Metab (2005) 1.33
Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas. J Clin Endocrinol Metab (2008) 1.33
Late recurrences of Cushing's disease after initial successful transsphenoidal surgery. J Clin Endocrinol Metab (2007) 1.33
AutoDecon: a robust numerical method for the quantification of pulsatile events. Methods Enzymol (2009) 1.33
p21(Cip1) restrains pituitary tumor growth. Proc Natl Acad Sci U S A (2008) 1.31
Loss of expression of GADD45 gamma, a growth inhibitory gene, in human pituitary adenomas: implications for tumorigenesis. J Clin Endocrinol Metab (2002) 1.29
Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells. Endocrinology (2003) 1.29
Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development (2010) 1.28
Ghrelin modulates the downstream molecules of insulin signaling in hepatoma cells. J Biol Chem (2001) 1.28
The effects of vertical sleeve gastrectomy in rodents are ghrelin independent. Gastroenterology (2012) 1.28
Determinants of skeletal loss and recovery in anorexia nervosa. J Clin Endocrinol Metab (2006) 1.27
Alterations in cortisol secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism. J Clin Endocrinol Metab (2004) 1.26
Changing patterns in diagnosis and therapy of acromegaly over two decades. J Clin Endocrinol Metab (2008) 1.25
Nutrient intake in community-dwelling adolescent girls with anorexia nervosa and in healthy adolescents. Am J Clin Nutr (2006) 1.25
Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects. J Clin Endocrinol Metab (2003) 1.25
The influence of growth hormone status on physical impairments, functional limitations, and health-related quality of life in adults. Endocr Rev (2006) 1.24
Long-term safety of pegvisomant in patients with acromegaly: comprehensive review of 1288 subjects in ACROSTUDY. J Clin Endocrinol Metab (2012) 1.24
Functional role of estrogen in pituitary tumor pathogenesis. J Clin Invest (2002) 1.24
A critical analysis of pituitary tumor shrinkage during primary medical therapy in acromegaly. J Clin Endocrinol Metab (2005) 1.23
Acromegaly. Endocrinol Metab Clin North Am (2008) 1.23
Comparison of DXA and CT in the assessment of body composition in premenopausal women with obesity and anorexia nervosa. Obesity (Silver Spring) (2010) 1.23
Distal radius in adolescent girls with anorexia nervosa: trabecular structure analysis with high-resolution flat-panel volume CT. Radiology (2008) 1.23
Hypercortisolemia is associated with severity of bone loss and depression in hypothalamic amenorrhea and anorexia nervosa. J Clin Endocrinol Metab (2009) 1.22
Xanthomatous pituitary lesions: a report of two cases and review of the literature. Pituitary (2003) 1.22
Weight gain and restoration of menses as predictors of bone mineral density change in adolescent girls with anorexia nervosa-1. J Clin Endocrinol Metab (2007) 1.20
A critical analysis of clinically available somatostatin analog formulations for therapy of acromegaly. J Clin Endocrinol Metab (2008) 1.19
Increased expression of angiogenic genes in the brains of mouse meg3-null embryos. Endocrinology (2010) 1.19
Ipilimumab-induced hypophysitis: a detailed longitudinal analysis in a large cohort of patients with metastatic melanoma. J Clin Endocrinol Metab (2014) 1.19
Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes. Proc Natl Acad Sci U S A (2003) 1.19
Cloning and characterization of the 5(')-flanking region of the human ghrelin gene. Biochem Biophys Res Commun (2003) 1.18
Preadipocyte factor-1 is associated with marrow adiposity and bone mineral density in women with anorexia nervosa. J Clin Endocrinol Metab (2009) 1.18
Young women with cold-activated brown adipose tissue have higher bone mineral density and lower Pref-1 than women without brown adipose tissue: a study in women with anorexia nervosa, women recovered from anorexia nervosa, and normal-weight women. J Clin Endocrinol Metab (2012) 1.18
PPAR-gamma receptor ligands: novel therapy for pituitary adenomas. J Clin Invest (2003) 1.18
Early multipotential pituitary focal hyperplasia in the alpha-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice. Mol Endocrinol (2005) 1.18
Relationships between serum adipokines, insulin levels, and bone density in girls with anorexia nervosa. J Clin Endocrinol Metab (2007) 1.18
Effects of exercise training and metformin on body composition and cardiovascular indices in HIV-infected patients. AIDS (2004) 1.18
Endocrine late effects after bone marrow transplant. Br J Haematol (2002) 1.17