Published in Prog Cell Cycle Res on January 01, 2003
Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proc Natl Acad Sci U S A (2006) 1.75
p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress. Mol Biol Cell (2004) 1.35
Effects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53. Cancer Prev Res (Phila) (2008) 1.34
Viral and cell cycle-regulated kinases in cytomegalovirus-induced pseudomitosis and replication. PLoS Pathog (2007) 1.29
ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence. Cancer Res (2009) 1.27
Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy. Mol Cancer (2009) 1.23
Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells. Biochem J (2007) 1.20
Signaling pathways that regulate cell division. Cold Spring Harb Perspect Biol (2012) 1.12
TSPY potentiates cell proliferation and tumorigenesis by promoting cell cycle progression in HeLa and NIH3T3 cells. BMC Cancer (2006) 1.07
Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells. Nat Commun (2014) 1.07
Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy. Circ Res (2016) 1.05
Nuclear export is evolutionarily conserved in CVC paired-like homeobox proteins and influences protein stability, transcriptional activation, and extracellular secretion. Mol Cell Biol (2005) 1.02
Overexpressions of Cyclin B1, cdc2, p16 and p53 in human breast cancer: the clinicopathologic correlations and prognostic implications. Yonsei Med J (2011) 0.99
Activity of the heat shock protein 90 inhibitor ganetespib in melanoma. PLoS One (2013) 0.97
A rationally designed histone deacetylase inhibitor with distinct antitumor activity against ovarian cancer. Neoplasia (2009) 0.96
Chlamydia trachomatis infection induces cleavage of the mitotic cyclin B1. Infect Immun (2006) 0.95
Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1. Mol Cell Biol (2006) 0.94
Interferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cells. Cancer Lett (2011) 0.92
CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression. Proc Natl Acad Sci U S A (2005) 0.90
O2 enhancement of human trophoblast differentiation and hCYP19 (aromatase) gene expression are mediated by proteasomal degradation of USF1 and USF2. Mol Cell Biol (2005) 0.90
Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis. Oncotarget (2015) 0.88
β-elemene effectively suppresses the growth and survival of both platinum-sensitive and -resistant ovarian tumor cells. Anticancer Res (2012) 0.88
Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells. Mol Biol Cell (2008) 0.87
Varicella-zoster virus infection of human foreskin fibroblast cells results in atypical cyclin expression and cyclin-dependent kinase activity. J Virol (2006) 0.85
Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine. BMC Cell Biol (2006) 0.84
Molecular interactions of human immunodeficiency virus type 1 with primary human oral keratinocytes. J Virol (2005) 0.84
Thioredoxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest. Invest New Drugs (2010) 0.83
4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway. J Biol Chem (2013) 0.83
Platelet-activating factor induces cell cycle arrest and disrupts the DNA damage response in mast cells. Cell Death Dis (2015) 0.82
Aronia melanocarpa juice induces a redox-sensitive p73-related caspase 3-dependent apoptosis in human leukemia cells. PLoS One (2012) 0.82
Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins. Oncotarget (2015) 0.82
Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells. Cell Death Dis (2014) 0.80
Distinct pools of cdc25C are phosphorylated on specific TP sites and differentially localized in human mitotic cells. PLoS One (2010) 0.80
Polo-like kinase 1 enhances survival and mutagenesis after genotoxic stress in normal cells through cell cycle checkpoint bypass. Carcinogenesis (2010) 0.79
The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer. BMC Cancer (2012) 0.78
Transcription factor STOX1A promotes mitotic entry by binding to the CCNB1 promotor. PLoS One (2012) 0.78
Nicotine overrides DNA damage-induced G1/S restriction in lung cells. PLoS One (2011) 0.77
STIP overexpression confers oncogenic potential to human non-small cell lung cancer cells by regulating cell cycle and apoptosis. J Cell Mol Med (2015) 0.76
In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells. Br J Pharmacol (2014) 0.76
Novel combretastatin A-4 derivative XN0502 induces cell cycle arrest and apoptosis in A549 cells. Invest New Drugs (2010) 0.76
O-desmethylangolensin inhibits the proliferation of human breast cancer MCF-7 cells by inducing apoptosis and promoting cell cycle arrest. Oncol Lett (2013) 0.76
Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases. Proteomes (2015) 0.75
Dynamic Alterations to α-Actinin Accompanying Sarcomere Disassembly and Reassembly during Cardiomyocyte Mitosis. PLoS One (2015) 0.75
Single-cell, single-mRNA analysis of Ccnb1 promoter regulation. Sci Rep (2017) 0.75
CDK inhibitors for muscle stem cell differentiation and self-renewal. J Phys Fit Sports Med (2017) 0.75
Importance of tuberin in carcinogenesis. Oncol Lett (2017) 0.75
Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2. J Cell Biol (2002) 1.24
Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation. J Biol Chem (2002) 1.15
Constitutively activated FGFR3 mutants signal through PLCgamma-dependent and -independent pathways for hematopoietic transformation. Blood (2005) 1.13
A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids. PLoS One (2009) 1.07
Human Spy1 promotes survival of mammalian cells following DNA damage. Cancer Res (2003) 1.06
Spy1 interacts with p27Kip1 to allow G1/S progression. Mol Biol Cell (2003) 1.05
The Spy1/RINGO family represents a novel mechanism regulating mammary growth and tumorigenesis. Cancer Res (2008) 1.02
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27. Cell Cycle (2007) 1.01
Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation. J Biol Chem (2006) 0.95
Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells. Cancer Res (2008) 0.93
The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation. J Biol Chem (2004) 0.93
Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC. Oncogene (2005) 0.93
The receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling. PLoS One (2010) 0.91
The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis. Cell Cycle (2009) 0.90
Speedy/RINGO regulation of CDKs in cell cycle, checkpoint activation and apoptosis. Cell Cycle (2007) 0.89
Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling. Cell Cycle (2014) 0.85
KIDs rule: regulatory phosphorylation of RTKs. Trends Biochem Sci (2013) 0.82
Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1. EMBO Rep (2002) 0.81
The tumor suppressor tuberin regulates mitotic onset through the cellular localization of cyclin B1. Cell Cycle (2011) 0.80
Early human prostate adenocarcinomas harbor androgen-independent cancer cells. PLoS One (2013) 0.79
Suppression of severe achondroplasia with developmental delay and acanthosis nigricans by the p.Thr651Pro mutation. Am J Med Genet A (2013) 0.75