Effect of a novel 5-HT3 receptor agonist MKC-733 on upper gastrointestinal motility in humans.

PubWeight™: 0.91‹?›

🔗 View Article (PMID 14616171)

Published in Aliment Pharmacol Ther on November 15, 2003

Authors

N S Coleman1, L Marciani, E Blackshaw, J Wright, M Parker, T Yano, S Yamazaki, P Q Chan, K Wilde, P A Gowland, A C Perkins, R C Spiller

Author Affiliations

1: Division of Gastroenterology, School of Medical and Surgical Sciences, University Hospital, Nottingham, UK.

Articles citing this

Impaired gastric accommodation and its role in dyspepsia. Gut (2006) 1.31

Serotonin pharmacology in the gastrointestinal tract: a review. Naunyn Schmiedebergs Arch Pharmacol (2008) 1.18

Physiological parameters for oral delivery and in vitro testing. Mol Pharm (2010) 1.18

Challenges to the therapeutic pipeline for irritable bowel syndrome: end points and regulatory hurdles. Gastroenterology (2008) 1.14

Serotonin is a sword and a shield of the bowel: serotonin plays offense and defense. Trans Am Clin Climatol Assoc (2012) 1.09

Pharmacology of serotonin: what a clinician should know. Gut (2004) 1.02

Classification and functions of enteroendocrine cells of the lower gastrointestinal tract. Int J Exp Pathol (2011) 0.98

Treating irritable bowel syndrome: overview, perspective and future therapies. Br J Pharmacol (2004) 0.96

Current and novel therapeutic options for irritable bowel syndrome management. Dig Liver Dis (2009) 0.93

Emerging Pharmacologic Therapies for Constipation-predominant Irritable Bowel Syndrome and Chronic Constipation. J Neurogastroenterol Motil (2014) 0.88

Role of central vagal 5-HT3 receptors in gastrointestinal physiology and pathophysiology. Front Neurosci (2015) 0.82

Glucose-dependent trafficking of 5-HT3 receptors in rat gastrointestinal vagal afferent neurons. Neurogastroenterol Motil (2012) 0.82

Effects of pregnane glycosides on food intake depend on stimulation of the melanocortin pathway and BDNF in an animal model. J Agric Food Chem (2013) 0.78

Aripiprazole an atypical antipsychotic protects against ethanol induced gastric ulcers in rats. Int J Clin Exp Med (2014) 0.77

Effects of 5-HT2B, 5-HT3 and 5-HT4 receptor antagonists on gastrointestinal motor activity in dogs. World J Gastroenterol (2013) 0.76

Effects of ondansetron on gastric tone and motility changes induced by a prolonged intraduodenal infusion of nutrients. Results of a placebo-controlled study. Dig Dis Sci (2007) 0.75

Serotonergic Mechanisms Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance. Handb Exp Pharmacol (2016) 0.75

Articles by these authors

(truncated to the top 100)

Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. J Mol Evol (1985) 47.78

Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States. Science (1999) 18.55

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med (2000) 13.13

Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol (1999) 7.60

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev (2001) 7.60

Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1. DNA Res (1999) 7.39

Management of proximal femoral fractures 2011: Association of Anaesthetists of Great Britain and Ireland. Anaesthesia (2012) 7.11

Entrainment of the circadian clock in the liver by feeding. Science (2001) 7.09

Cost analysis of early discharge after hip fracture. BMJ (1993) 6.64

The euthanasia controversy. Decision-making in extreme cases. Med J Aust (1995) 5.96

The role of the church in developing the law. J Med Ethics (2002) 5.39

Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science (2000) 4.94

Proteins of vesicular stomatitis virus: kinetics and cellular sites of synthesis. J Virol (1970) 4.85

Use of technology in children's dietary assessment. Eur J Clin Nutr (2009) 4.15

Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report. Surgery (1990) 3.93

Health-related quality of life after knee replacement. J Bone Joint Surg Am (1998) 3.88

Comparison of cross-sectional renal function measurements in African Americans with hypertensive nephrosclerosis and of primary formulas to estimate glomerular filtration rate. Am J Kidney Dis (2001) 3.68

Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Virology (1997) 3.62

Ultrasonically guided subsegmentectomy. Surg Gynecol Obstet (1985) 3.42

Independent introduction of two major HIV-1 genotypes into distinct high-risk populations in Thailand. Lancet (1993) 3.28

Occult vitamin D deficiency in postmenopausal US women with acute hip fracture. JAMA (1999) 3.14

Surveillance of antibody to measles, mumps, and rubella by age. BMJ (1988) 3.11

Staining methods of Australia antigen in paraffin section--detection of cytoplasmic inclusion bodies. Jpn J Exp Med (1974) 3.08

Surgery for small liver cancers. Semin Surg Oncol (1993) 3.00

Cross-infection in Measles Patients. Br Med J (1945) 2.94

Complete nucleotide sequence and genetic organization of Aichi virus, a distinct member of the Picornaviridae associated with acute gastroenteritis in humans. J Virol (1998) 2.85

Continuous positive airways pressure for obstructive sleep apnoea in adults. Cochrane Database Syst Rev (2006) 2.82

Implementation of the Medical Information, Communication, and Archive System (MICAS). J Digit Imaging (1997) 2.80

Transmural extent of acute myocardial infarction predicts long-term improvement in contractile function. Circulation (2001) 2.73

Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax. Oncogene (1997) 2.69

Successful en-bloc resection of large superficial tumors in the stomach and colon using sodium hyaluronate and small-caliber-tip transparent hood. Endoscopy (2003) 2.67

The Otto E. Aufranc Award: The role of labral lesions to development of early degenerative hip disease. Clin Orthop Relat Res (2001) 2.63

The professional perception of orthodontic treatment complexity. Br Dent J (1997) 2.62

Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1. Cell (1998) 2.57

Purification and partial characterization of heat-stable enterotoxin of enterotoxigenic Escherichia coli. Infect Immun (1979) 2.55

Muir-Torre syndrome: case report of a patient with concurrent jejunal and ureteral cancer and a review of the literature. J Am Acad Dermatol (1999) 2.55

Structural organization and expression of the mouse estrogen receptor. Mol Endocrinol (1987) 2.54

Revealing false paternity: some ethical considerations. Lancet (2001) 2.48

Cost of extracorporeal life support in pediatric patients with acute respiratory failure. Crit Care Med (1998) 2.43

The molecular epidemiology of HIV in Asia. AIDS (1994) 2.37

Architecture of the sarcomere matrix of skeletal muscle: immunoelectron microscopic evidence that suggests a set of parallel inextensible nebulin filaments anchored at the Z line. J Cell Biol (1988) 2.35

Randomized, prospective trial of pressure-limited versus volume-controlled ventilation in severe respiratory failure. Crit Care Med (1994) 2.35

Direct percutaneous transluminal angioplasty for acute middle cerebral artery occlusion. AJNR Am J Neuroradiol (1998) 2.34

CD3+, CD56+ aggressive variant of large granular lymphocyte leukemia. Blood (1994) 2.33

Regulation of skeletal muscle stiffness and elasticity by titin isoforms: a test of the segmental extension model of resting tension. Proc Natl Acad Sci U S A (1991) 2.31

Viscoelasticity of the sarcomere matrix of skeletal muscles. The titin-myosin composite filament is a dual-stage molecular spring. Biophys J (1993) 2.31

Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus. Nucleic Acids Res (1988) 2.28

Safety of complementary medicines should be monitored. BMJ (1995) 2.27

Redesign of PCR primers for mitochondrial cytochrome c oxidase subunit I for marine invertebrates and application in all-taxa biotic surveys. Mol Ecol Resour (2013) 2.27

Oral appliances for obstructive sleep apnoea. Cochrane Database Syst Rev (2006) 2.24

Retracted A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA. EMBO J (2001) 2.21

Systematic review of clinical effectiveness of pressurised metered dose inhalers versus other hand held inhaler devices for delivering corticosteroids in asthma. BMJ (2001) 2.20

Are specialist outreach clinics for orthodontic consultation effective? A randomised controlled trial. Br Dent J (2001) 2.18

Genome of a mononucleosis Epstein-Barr virus contains DNA fragments previously regarded to be unique to Burkitt's lymphoma isolates. Cell (1981) 2.17

Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17

Effect of omeprazole on the distribution of metronidazole, amoxicillin, and clarithromycin in human gastric juice. Gastroenterology (1996) 2.13

Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients. Am Rev Respir Dis (1992) 2.12

Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns. J Endocrinol (1993) 2.12

Comparative genome analysis of Campylobacter jejuni using whole genome DNA microarrays. FEBS Lett (2003) 2.11

The ileal brake--inhibition of jejunal motility after ileal fat perfusion in man. Gut (1984) 2.11

Recurrent gastrointestinal bleeding of obscure origin: report of 17 cases and a guide to logical management. Br J Surg (1983) 2.09

The urea breath test for Helicobacter pylori. Gut (1994) 2.07

Continuous positive airways pressure for obstructive sleep apnoea in adults. Cochrane Database Syst Rev (2006) 2.05

New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat Cell Biol (2000) 2.05

Systematic review of clinical effectiveness of pressurised metered dose inhalers versus other hand held inhaler devices for delivering beta (2 )agonists bronchodilators in asthma. BMJ (2001) 2.04

Failure of repeated injection sclerotherapy to improve long-term survival after oesophageal variceal bleeding. A five-year prospective controlled clinical trial. Lancet (1983) 2.01

Chronic jet-lag increases mortality in aged mice. Curr Biol (2006) 2.01

Chronic granulomatous disease: a syndrome of phagocyte oxidase deficiencies. Medicine (Baltimore) (1983) 2.01

A controlled double blind study of azathioprine in the management of Crohn's disease. Gut (1995) 2.00

Video-assisted extended thymectomy in patients with thymoma by lifting the sternum. Ann Thorac Surg (2001) 1.99

Do case studies mislead about the nature of reality? J Med Ethics (1999) 1.99

Mechanisms of hypersensitivity in IBS and functional disorders. Neurogastroenterol Motil (2007) 1.98

Safety of hemihepatic vascular occlusion during resection of the liver. Surg Gynecol Obstet (1987) 1.98

Primary repair of obstetric uterine rupture can be safely undertaken by non-specialist clinicians in rural Ethiopia: a case series of 386 women. BJOG (2012) 1.97

Recombinant RNA replicons derived from attenuated Venezuelan equine encephalitis virus protect guinea pigs and mice from Ebola hemorrhagic fever virus. Vaccine (2000) 1.95

Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins. Proc Natl Acad Sci U S A (1984) 1.94

Does locoregional radiation therapy improve survival in breast cancer? A meta-analysis. J Clin Oncol (2000) 1.92

Use of ethanol-induced tumor necrosis to palliate dysphagia in patients with esophagogastric cancer. Gastrointest Endosc (1990) 1.91

Reversible cardiac dysfunction associated with interferon alfa therapy in AIDS patients with Kaposi's sarcoma. N Engl J Med (1989) 1.88

Demographic variation in the rate of knee replacement: a multi-year analysis. Health Serv Res (1996) 1.87

Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile. J Cell Biol (1991) 1.85

Do clinical trials improve quality of care? A comparison of clinical processes and outcomes in patients in a clinical trial and similar patients outside a trial where both groups are managed according to a strict protocol. Qual Saf Health Care (2005) 1.85

Quality improvement for patients with hip fracture: experience from a multi-site audit. Qual Saf Health Care (2002) 1.83

Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature. Health Technol Assess (2001) 1.82

Clinical trial guidelines for pharmacological treatment of irritable bowel syndrome. Aliment Pharmacol Ther (2003) 1.82

The nuclear receptor co-repressor nrip1 (RIP140) is essential for female fertility. Nat Med (2000) 1.79

Malignant transformation of adenomatous hyperplasia to hepatocellular carcinoma. Lancet (1990) 1.75

Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae. Cell (1999) 1.73

The neurochip: a new multielectrode device for stimulating and recording from cultured neurons. J Neurosci Methods (1999) 1.72

Radioimmunodetection of human colorectal cancers by an anti-tumour monoclonal antibody. Lancet (1982) 1.71

Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase. Genes Cells (1998) 1.71

Chronic subdural hematoma, as an initial manifestation of glutaric aciduria type-1. Brain Dev (1993) 1.70

Risk factors for venous thrombosis in medical inpatients: validation of a thrombosis risk score. J Thromb Haemost (2004) 1.70

The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas. Br J Cancer (2009) 1.70

Information provision for stroke patients and their caregivers. Cochrane Database Syst Rev (2008) 1.69

Expression of E-cadherin and beta-catenin in human non-small cell lung cancer and the clinical significance. Clin Cancer Res (2000) 1.69

p53 mutation is associated with progression in follicular lymphomas. Blood (1993) 1.69

Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J Dairy Sci (1995) 1.68

Magnetization transfer phenomenon in the human brain at 7 T. Neuroimage (2009) 1.67

Disruption of Thermus thermophilus genes by homologous recombination using a thermostable kanamycin-resistant marker. FEBS Lett (2001) 1.66