Published in Acta Haematol on January 01, 2004
Role of apoptosis-inducing factor, proline dehydrogenase, and NADPH oxidase in apoptosis and oxidative stress. Cell Health Cytoskelet (2012) 1.04
T cell apoptosis and inflammatory bowel disease. Gut (2004) 1.00
Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim. Infect Immun (2008) 0.99
Differential expression of pro-inflammatory cytokines and a pro-apoptotic protein in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis. Tech Coloproctol (2008) 0.83
Alteration of mitochondrial function and cell sensitization to death. J Bioenerg Biomembr (2007) 0.82
Detection of epithelial apoptosis in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis. J Transl Med (2010) 0.78
Microarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibition. BMC Genomics (2010) 0.78
Pinus densiflora leaf essential oil induces apoptosis via ROS generation and activation of caspases in YD-8 human oral cancer cells. Int J Oncol (2011) 0.77
Reversal of Beta-Amyloid-Induced Neurotoxicity in PC12 Cells by Curcumin, the Important Role of ROS-Mediated Signaling and ERK Pathway. Cell Mol Neurobiol (2016) 0.76
Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways. Biosci Rep (2016) 0.75
Cellular apoptosis in the cardiorenal axis. Heart Fail Rev (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol (2006) 10.55
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature (2006) 9.77
Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature (2007) 7.17
Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity (2007) 6.75
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell (2008) 6.37
Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell (2007) 5.91
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity (2009) 4.49
Immunogenic cell death and DAMPs in cancer therapy. Nat Rev Cancer (2012) 3.76
RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome. Immunity (2011) 3.53
Necroptosis: the release of damage-associated molecular patterns and its physiological relevance. Immunity (2013) 3.22
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature (2011) 3.17
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. Biochim Biophys Acta (2006) 3.12
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity (2011) 3.10
RIP kinases at the crossroads of cell death and survival. Cell (2009) 3.04
Apoptosis and necrosis: detection, discrimination and phagocytosis. Methods (2008) 2.93
Caspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol (2007) 2.82
Neutrophil extracellular trap cell death requires both autophagy and superoxide generation. Cell Res (2010) 2.82
Toxic proteins released from mitochondria in cell death. Oncogene (2004) 2.78
The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology. Trends Immunol (2009) 2.74
Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes. Mol Cell Proteomics (2008) 2.64
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J (2012) 2.45
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood (2012) 2.43
Clearance of apoptotic and necrotic cells and its immunological consequences. Apoptosis (2006) 2.20
B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice. Blood (2010) 2.17
Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis. J Exp Med (2010) 2.15
Immunogenic cell death, DAMPs and anticancer therapeutics: an emerging amalgamation. Biochim Biophys Acta (2009) 2.07
Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation. Trends Immunol (2011) 2.05
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proc Natl Acad Sci U S A (2012) 1.97
Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice. Genome Biol (2013) 1.97
Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol (2011) 1.93
The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation. J Immunol (2007) 1.89
Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments. Expert Rev Vaccines (2009) 1.83
Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome. Sci Signal (2012) 1.82
Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection. J Immunol (2010) 1.79
Characterization of counterfeit artesunate antimalarial tablets from southeast Asia. Am J Trop Med Hyg (2006) 1.79
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis. Nat Genet (2011) 1.78
Major cell death pathways at a glance. Microbes Infect (2009) 1.77
Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1-mediated maturation and release of interleukin-1beta. J Biol Chem (2004) 1.70
Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock. Am J Respir Crit Care Med (2014) 1.68
Beclin1: a role in membrane dynamics and beyond. Autophagy (2012) 1.68
Hepatic tumor necrosis factor signaling and nuclear factor-kappaB: effects on liver homeostasis and beyond. Endocr Rev (2007) 1.67
Autophagy: for better or for worse. Cell Res (2011) 1.65
The emerging roles of serine protease cascades in the epidermis. Trends Biochem Sci (2009) 1.64
Molecular mechanisms and pathophysiology of necrotic cell death. Curr Mol Med (2008) 1.63
The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity. Immunity (2011) 1.63
TNFR1- and TNFR2-mediated signaling pathways in human kidney are cell type-specific and differentially contribute to renal injury. FASEB J (2005) 1.60
Programmed necrosis from molecules to health and disease. Int Rev Cell Mol Biol (2011) 1.58
Are metacaspases caspases? J Cell Biol (2007) 1.57
Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway. Cancer Cell (2012) 1.55
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death. Autophagy (2013) 1.55
M2e-based universal influenza A vaccine. Vaccine (2009) 1.52
Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin. Cancer Immunol Immunother (2011) 1.51
An influenza A vaccine based on tetrameric ectodomain of matrix protein 2. J Biol Chem (2008) 1.51
Caspase-14 reveals its secrets. J Cell Biol (2008) 1.47
Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production. Mol Biol Cell (2003) 1.47
Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis. J Biol Chem (2002) 1.45
Tumor necrosis factor-mediated cell death: to break or to burst, that's the question. Cell Mol Life Sci (2010) 1.44
Mitochondrial intermembrane proteins in cell death. Biochem Biophys Res Commun (2003) 1.44
ER stress-induced inflammation: does it aid or impede disease progression? Trends Mol Med (2012) 1.41
Laser ablation-inductively coupled plasma mass spectrometry for the characterization of pigments in prehistoric rock art. Anal Chem (2007) 1.38
CTA1-M2e-DD: a novel mucosal adjuvant targeted influenza vaccine. Vaccine (2008) 1.38
IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain (2011) 1.37
The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress. Biol Cell (2012) 1.35
The death-fold superfamily of homotypic interaction motifs. Trends Biochem Sci (2011) 1.35
Proteome-wide Identification of HtrA2/Omi Substrates. J Proteome Res (2007) 1.34
Expression, biological activities and mechanisms of action of A20 (TNFAIP3). Biochem Pharmacol (2010) 1.33
Improved design and intranasal delivery of an M2e-based human influenza A vaccine. Vaccine (2006) 1.32
The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection. Vaccine (2005) 1.31
SitePredicting the cleavage of proteinase substrates. Trends Biochem Sci (2009) 1.29
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD. J Biol Chem (2003) 1.28
NOD-like receptors and the innate immune system: coping with danger, damage and death. Cytokine Growth Factor Rev (2011) 1.28
Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity. Mol Cell Proteomics (2009) 1.27
Mx proteins: antiviral gatekeepers that restrain the uninvited. Microbiol Mol Biol Rev (2013) 1.22
A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions. J Biol Chem (2007) 1.22
Cell death in the skin. Apoptosis (2009) 1.22
Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly. J Virol (2012) 1.22
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation. J Biol Chem (2004) 1.20
Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2. Am J Pathol (2007) 1.20
Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules. PLoS One (2011) 1.20
DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown. Photochem Photobiol Sci (2011) 1.20
Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals. Nat Immunol (2009) 1.19
Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain. Neurobiol Dis (2010) 1.17
Regulation of the expression and processing of caspase-12. J Cell Biol (2003) 1.16
Methods for distinguishing apoptotic from necrotic cells and measuring their clearance. Methods Enzymol (2008) 1.13
NLRP3/caspase-1-independent IL-1beta production mediates diesel exhaust particle-induced pulmonary inflammation. J Immunol (2011) 1.13
Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination. J Immunol (2010) 1.13
Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: role in the Ca2+ sensitization of myosin light chain20 phosphorylation. Mol Pharmacol (2003) 1.12
Enterocyte death and intestinal barrier maintenance in homeostasis and disease. Trends Mol Med (2011) 1.12
Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes. FASEB J (2004) 1.12
Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity. J Biol Chem (2004) 1.12